Luca Massimi

Summary

Country: Italy

Publications

  1. ncbi Late closure of the stoma by spreading of a periaqueductal glioma: an unusual failure of endoscopic third ventriculostomy. Case report
    Luca Massimi
    Pediatric Neurosurgery Unit, Catholic University Medical School, Rome, Italy
    J Neurosurg 104:197-201. 2006
  2. ncbi Mozart: a metropolitan legend with pediatric neurosurgical implications
    Luca Massimi
    Pediatric Neurosurgery Unit, Institute of Neurosurgery, Catholic University Medical School, Largo A Gemelli, 8, 00168, Rome, Italy
    Childs Nerv Syst 22:451-3. 2006
  3. ncbi Surgical treatment of posthemorrhagic infantile hydrocephalus
    L Massimi
    Department of Pediatric Neurosurgery, Sacro Cuore Catoholic University, Policlinico A Gemelli, Rome, Italy
    Minerva Pediatr 65:417-25. 2013
  4. doi Mini-invasive surgical technique for sagittal craniosynostosis
    Luca Massimi
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    Childs Nerv Syst 28:1341-5. 2012
  5. doi Isolated sagittal craniosynostosis: definition, classification, and surgical indications
    Luca Massimi
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    Childs Nerv Syst 28:1311-7. 2012
  6. doi Abrupt clinical onset of Chiari type I/syringomyelia complex: clinical and physiopathological implications
    Luca Massimi
    Institute of Neurosurgery A Gemelli Hospital, Largo A Gemelli, 8, 00168, Rome, Italy
    Neurosurg Rev 35:321-9; discussion 329. 2012
  7. doi History of Chiari type I malformation
    Luca Massimi
    Department of Neurosciences, Pediatric Neurosurgery, A Gemelli Hospital, Rome, Italy
    Neurol Sci 32:S263-5. 2011
  8. doi Natural history of Chiari type I malformation in children
    Luca Massimi
    Department of Neurosciences, Pediatric Neurosurgery, A Gemelli Hospital, Rome, Italy
    Neurol Sci 32:S275-7. 2011
  9. doi Section of the filum terminale: is it worthwhile in Chiari type I malformation?
    Luca Massimi
    Department of Neurosciences, Pediatric Neurosurgery, A Gemelli Hospital, Rome, Italy
    Neurol Sci 32:S349-51. 2011
  10. ncbi Segmental spinal myoclonus and metastatic cervical ganglioglioma: an unusual association
    Luca Massimi
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    J Child Neurol 24:365-9. 2009

Collaborators

Detail Information

Publications63

  1. ncbi Late closure of the stoma by spreading of a periaqueductal glioma: an unusual failure of endoscopic third ventriculostomy. Case report
    Luca Massimi
    Pediatric Neurosurgery Unit, Catholic University Medical School, Rome, Italy
    J Neurosurg 104:197-201. 2006
    ..The authors suggest tumor extension along the diencephalic neural pathways as the possible cause of ETV failure in this patient...
  2. ncbi Mozart: a metropolitan legend with pediatric neurosurgical implications
    Luca Massimi
    Pediatric Neurosurgery Unit, Institute of Neurosurgery, Catholic University Medical School, Largo A Gemelli, 8, 00168, Rome, Italy
    Childs Nerv Syst 22:451-3. 2006
  3. ncbi Surgical treatment of posthemorrhagic infantile hydrocephalus
    L Massimi
    Department of Pediatric Neurosurgery, Sacro Cuore Catoholic University, Policlinico A Gemelli, Rome, Italy
    Minerva Pediatr 65:417-25. 2013
    ..Immaturity of the CSF re-adsorption pathways, obstruction of the subarachnoid spaces and low intracranial pressure are the main causes of endoscopy failures. ..
  4. doi Mini-invasive surgical technique for sagittal craniosynostosis
    Luca Massimi
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    Childs Nerv Syst 28:1341-5. 2012
    ..Herein, the surgical steps of a personal, mini-invasive technique used to decrease the impact of the surgical scar are described...
  5. doi Isolated sagittal craniosynostosis: definition, classification, and surgical indications
    Luca Massimi
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    Childs Nerv Syst 28:1311-7. 2012
    ..On the other hand, the surgical correction may show a protective effect on some visual skills, like the ability to fix and follow, and the fixation shift...
  6. doi Abrupt clinical onset of Chiari type I/syringomyelia complex: clinical and physiopathological implications
    Luca Massimi
    Institute of Neurosurgery A Gemelli Hospital, Largo A Gemelli, 8, 00168, Rome, Italy
    Neurosurg Rev 35:321-9; discussion 329. 2012
    ..About 87 % of patients of this review were asymptomatic prior to their acute onset. The problem of the management of asymptomatic subjects is still open...
  7. doi History of Chiari type I malformation
    Luca Massimi
    Department of Neurosciences, Pediatric Neurosurgery, A Gemelli Hospital, Rome, Italy
    Neurol Sci 32:S263-5. 2011
    ....
  8. doi Natural history of Chiari type I malformation in children
    Luca Massimi
    Department of Neurosciences, Pediatric Neurosurgery, A Gemelli Hospital, Rome, Italy
    Neurol Sci 32:S275-7. 2011
    ..This analysis shows a favorable natural outcome of CIM in children, thus suggesting a conservative management in asymptomatic cases. However, multicentric studies are required to validate this data...
  9. doi Section of the filum terminale: is it worthwhile in Chiari type I malformation?
    Luca Massimi
    Department of Neurosciences, Pediatric Neurosurgery, A Gemelli Hospital, Rome, Italy
    Neurol Sci 32:S349-51. 2011
    ..On these grounds, a relationship between CIM and OTCS is hard to be demonstrated, (3) a subgroup of patients with CIM suffering from OTCS may exist and benefit from SFT...
  10. ncbi Segmental spinal myoclonus and metastatic cervical ganglioglioma: an unusual association
    Luca Massimi
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    J Child Neurol 24:365-9. 2009
    ....
  11. ncbi Effectiveness of a limited invasive scalp approach in the correction of sagittal craniosynostosis
    Luca Massimi
    Pediatrc Neurosurgery, Catholic University Medical School, Rome, Italy
    Childs Nerv Syst 23:1389-401. 2007
    ..Mini-invasive approaches are particularly useful in the very young infant as they are associated with a minor surgical risk. Furthermore, they are weighted by a minor cosmetic impact related to a less extended surgical scar...
  12. doi On the changing epidemiology of hydrocephalus
    Luca Massimi
    Paediatric Neurosurgery Institute of Neurosurgery, Policlinico A Gemelli, Largo A Gemelli, 8, 00168, Rome, Italy
    Childs Nerv Syst 25:795-800. 2009
    ..The purpose of this study is to evaluate the changing epidemiology of paediatric hydrocephalus over the past three decades in a single institution...
  13. doi Endoscopic third ventriculostomy for the management of Chiari I and related hydrocephalus: outcome and pathogenetic implications
    Luca Massimi
    Institute of Neurosurgery, A Gemelli Hospital, Rome, Italy
    Neurosurgery 68:950-6. 2011
    ..Hydrocephalus affects 7% to 10% of patients with Chiari I malformation (CIM). It can be successfully treated by endoscopic third ventriculostomy (ETV), possibly improving related CIM and syringomyelia...
  14. doi Sudden onset of Chiari malformation Type I in previously asymptomatic patients
    Luca Massimi
    Department of Neurosciences, Institute of Neurosurgery, A Gemelli Hospital, Rome, Italy
    J Neurosurg Pediatr 8:438-42. 2011
    ..All 3 patients showed a CM-I/syringomyelia complex at diagnosis, and all of them had a good neurological outcome after surgery despite the ominous clinical presentation...
  15. doi Quality of postoperative course in children: endoscopic endonasal surgery versus sublabial microsurgery
    Luca Massimi
    Paediatric Neurosurgery, A Gemelli Hospital, Rome, Italy
    Acta Neurochir (Wien) 153:843-9. 2011
    ..No information on the trend of the postoperative course is currently available. The goal of this paper is to assess the impact of these two different transsphenoidal approaches on the postoperative course...
  16. ncbi Management of optic-hypothalamic gliomas in children: still a challenging problem
    Luca Massimi
    Catholic University Medical School, Pediatric Neurosurgery, Institute of Neurosurgery, Largo A Gemelli 8, 00168, Rome, Italy
    Expert Rev Anticancer Ther 7:1591-610. 2007
    ..The prognosis of OPHGs is quite good, with regard to the overall survival rate (70-100% at 5 years), but less favorable in terms of late morbidity...
  17. doi Preoperative and postoperative neurological, neuropsychological and behavioral impairment in children with posterior cranial fossa astrocytomas and medulloblastomas: the role of the tumor and the impact of the surgical treatment
    Concezio Di Rocco
    Paediatric Neurosurgery Unit, Catholic University Medical School, Largo Agostino Gemelli 8, Rome, Italy
    Childs Nerv Syst 26:1173-88. 2010
    ....
  18. doi Heralding cerebellar mutism: evidence for pre-surgical language impairment as primary risk factor in posterior fossa surgery
    Concezio Di Rocco
    Paediatric Neurosurgery, Catholic University Medical School, Policlinic A Gemelli, Largo Agostino Gemelli, 8, 00168, Rome, Italy
    Cerebellum 10:551-62. 2011
    ..In the present series, children with normal pre-operative language function did not develop post-operative mutism...
  19. doi The use of a reconstituted collagen foil dura mater substitute in paediatric neurosurgical procedures--experience in 47 patients
    Benedetta Ludovica Pettorini
    Paediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    Br J Neurosurg 24:51-4. 2010
    ..We report our experience with a new collagen foil (TissuDura, Baxter Healthcare SA, Switzerland) utilized as dural substitute in paediatric neurosurgical procedures...
  20. doi Antibiotic impregnated external ventricular drainage and third ventriculostomy in the management of hydrocephalus associated with posterior cranial fossa tumours
    Gianpiero Tamburrini
    Paediatric Neurosurgery, Institute of Neurosurgery, Catholic University Medical School, Largo A Gemelli, 8, 00168 Rome, Italy
    Acta Neurochir (Wien) 150:1049-55; discussion 1055-6. 2008
    ....
  21. doi Lim mineralization protein is involved in the premature calvarial ossification in sporadic craniosynostoses
    Wanda Lattanzi
    Institute of Anatomy and Cell Biology, Universita Cattolica S Cuore, Rome, Italy
    Bone 52:474-84. 2013
    ..the molecular basis of the overactive osteogenic process may at least in part involve a deregulation of the LMP-related pathway in calvarial cells...
  22. doi Retrieval of ventricular catheter with the aid of endoscopy: technical note
    Benedetta Ludovica Pettorini
    Institute of Neurosurgery, Division of Pediatric Neurosurgery, Catholic University of Rome, Rome, Italy
    J Neurosurg Pediatr 2:71-4. 2008
    ..The removal of an unnecessary and no longer useful prosthetic device that is a possible focus of infection justifies endoscopic treatment, which, in this experience, is not associated with morbidity...
  23. doi Severe subdural hemorrhage due to minimal prenatal trauma
    Marco Piastra
    Paediatric Intensive Care Unit, Catholic University Medical School, A Gemelli Hospital, L go Gemelli 8, 00168 Rome, Italy
    J Neurosurg Pediatr 4:543-6. 2009
    ..After birth, brain compression required a complex neurosurgical intervention because simple hematoma evacuation was not possible. The clinical and neurological outcome at 6 months was excellent, as confirmed by the neuroimaging findings...
  24. pmc Sleep disordered breathing in children and adolescents with Chiari malformation type I
    Anna Losurdo
    Institute of Neurology, Catholic University, Rome, Italy
    J Clin Sleep Med 9:371-7. 2013
    ..Chiari malformation Type I (CM-I) has been associated with sleep disordered breathing (SDB). The aim of this study was to evaluate the prevalence of SDB in CM-I and its clinical correlates in a population of children and adolescents...
  25. doi CSF otorrhea after anterior temporal craniotomy due to hyperpneumatization of the temporal bone
    Benedetta Ludovica Pettorini
    Institute of Neurosurgery, Catholic University, Rome, Italy
    Pediatr Neurosurg 44:176-7. 2008
  26. ncbi Thoracic lipomeningocele associated with diastematomyelia, tethered spinal cord, and hydrocephalus. Case report
    Benedetta Ludovica Pettorini
    Department of Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    J Neurosurg 106:394-7. 2007
    ..The authors discuss the rare association of these clinical entities and conclude that complete spine and brain neuroimaging studies are necessary for the correct surgical planning of this kind of malformation...
  27. doi Long-term neuropsychological development in single-suture craniosynostosis treated early
    Daniela Chieffo
    Department of Pediatric Neurology, Catholic University Medical School, Rome, Italy
    J Neurosurg Pediatr 5:232-7. 2010
    ..The authors evaluated the results of complete cognitive function examinations in a series of 65 adolescents who had undergone surgery for sagittal or unicoronal craniosynostosis when they were younger than 1 year old...
  28. doi The natural history of the Chiari Type I anomaly
    Federica Novegno
    Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A Gemelli 1, Rome, Italy
    J Neurosurg Pediatr 2:179-87. 2008
    ..The decision of whether or not to operate is more difficult in these patients than in those with clear symptoms because of the lack of information about the natural course of this disease...
  29. doi The role of inflammation in the genesis of the cystic component of craniopharyngiomas
    Benedetta Ludovica Pettorini
    Institute of Neurosurgery, Division of Paediatric Neurosurgery, Catholic University of Rome, Largo Agostino Gemelli, 8, 00168, Rome, Italy
    Childs Nerv Syst 26:1779-84. 2010
    ..Only a few studies have addressed the molecular characterization of the cyst fluid so far and the mechanisms of action of intracystic agents are not clearly understood yet...
  30. doi Giant subcortical heterotopia involving the temporo-parieto-occipital region: a challenging cause of drug-resistant epilepsy
    Federica Novegno
    Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A Gemelli, 8, 00168 Rome, Italy
    Epilepsy Res 87:88-94. 2009
    ..Patients affected by giant subcortical heterotopias can have a favourable prognosis after the surgical removal of the malformation, even following long-lasting epilepsy...
  31. ncbi The role of endoscopic choroid plexus coagulation in the surgical management of bilateral choroid plexuses hyperplasia
    Gianpiero Tamburrini
    Section of Pediatric Neurosurgery, Institute of Neurosurgery, Catholic University Medical School, Largo Gemelli 8, 00168, Rome, Italy
    Childs Nerv Syst 22:605-8. 2006
    ..Endoscopic coagulation of the choroid plexuses has been recently proposed as an alternative to open surgical plexectomy. However, the effectiveness of the procedure in controlling CSF overproduction is still debated...
  32. doi Endoscopic transventricular positioning of intracystic catheter for treatment of craniopharyngioma. Technical note
    Benedetta L Pettorini
    Pediatric Neurosurgery Unit, Catholic University Medical School, Largo Agostino Gemelli, Rome, Italy
    J Neurosurg Pediatr 4:245-8. 2009
    ..The authors' experience favors the use of neuroendoscopic positioning of intracystic catheters as safer than open and stereotactic approaches...
  33. ncbi Surgical management of craniopharyngiomas--experience with a pediatric series
    Concezio Di Rocco
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    J Pediatr Endocrinol Metab 19:355-66. 2006
    ..In case of huge tumors involving the hypothalamus, a more conservative resection should be performed, followed by a 'wait and see' policy or possible radiotherapy...
  34. ncbi 12-year-old boy with multiple brain masses
    Luca Massimi
    Department of Bio images and Radiological Sciences, Catholic University Medical School, Rome, Italy
    Brain Pathol 20:679-82. 2010
    ..Explanations of this very unusual association include radio-induced tumors, second tumors developing from remnants of medulloblastoma cancer stem cells, or the changing histology after adjuvant therapy...
  35. doi Endoscopic septostomy through a standard precoronal ventricular access: feasibility and effectiveness
    Gianpiero Tamburrini
    Pediatric Neurosurgery Unit, Catholic University Medical School, Largo Agostino Gemelli, 8, 00168, Rome, Italy
    Acta Neurochir (Wien) 154:1517-22. 2012
    ..In particular, the choice of the ventricular access has been recently debated. We investigated the results of endoscopic septostomy performed through a standard precoronal ventricular access using a rigid endoscope...
  36. doi Complications of delayed cranial repair after decompressive craniectomy in children less than 1 year old
    Paolo Frassanito
    Pediatric Neurosurgery, Policlinic A Gemelli, Catholic Medical School, Rome, Italy
    Acta Neurochir (Wien) 154:927-33. 2012
    ..However, only a few dedicated papers can be found in the literature...
  37. doi Radiation-induced brain tumours after central nervous system irradiation in childhood: a review
    Benedetta Ludovica Pettorini
    Institute of Neurosurgery, Division of Paediatric Neurosurgery, Catholic University of Rome, Largo Agostino Gemelli, 8, 00168, Rome, Italy
    Childs Nerv Syst 24:793-805. 2008
    ..Age-related cerebral vulnerability could be a specific factor in the genesis of these complications...
  38. ncbi Unusual presentation of intradural endodermal cysts in young children under 2 years of age. Report of two cases
    Federica Novegno
    Department of Pediatric Neurosurgery, Catholic University Medical School, Largo A Gemelli 1, 00168 Rome, Italy
    Eur J Pediatr 165:613-7. 2006
    ....
  39. doi Unilateral hyperplasia of the left posterior arch and associated vertebral schisis at C6 level
    Giuseppe Esposito
    Department of Pediatric Neurosurgery, Catholic University, School of Medicine, Rome, Italy
    Skeletal Radiol 38:1191-5. 2009
    ..Only one previous study has reported a similar congenital anomaly, but it was limited to the left side of the spinous process...
  40. doi Occipital sinus pericranii superseding both jugular veins: description of two rare pediatric cases
    Paolo Frassanito
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    Neurosurgery 72:E1054-8; dicussion 1058. 2013
    ..The extracranial venous drainage of the brain is provided mainly by the jugular veins with the variable participation of extrajugular pathways...
  41. doi Anterior plagiocephaly: epidemiology, clinical findings,diagnosis, and classification. A review
    Concezio Di Rocco
    Paediatric Neurosurgery, Catholic University Medical School, A Gemelli Hospital, L go A Gemelli 8, 00168, Rome, Italy
    Childs Nerv Syst 28:1413-22. 2012
    ..Anterior plagiocephaly is the direct cause of oculomotor anomalies, with a characteristic strabismus, and of progressive asymmetrical maldevelopment of the face, craniovertebral junction, and cervical spine...
  42. doi Cerebrospinal fluid top-down proteomics evidenced the potential biomarker role of LVV- and VV-hemorphin-7 in posterior cranial fossa pediatric brain tumors
    Claudia Desiderio
    Istituto di Chimica del Riconoscimento Molecolare, Consiglio Nazionale delle Ricerche, Rome, Italy
    Proteomics 12:2158-66. 2012
    ..These results ascribed a relevant biological role to LVV- and VV-h7 peptides in the disease and a strong potential as biomarkers. Their analysis in POST surgery CSF could be used to predict patient prognosis...
  43. doi Sudden paraplegia in a case of apparently isolated frontal embryonal tumour with abundant neuropil and true rosettes
    Paolo Frassanito
    Paediatric Neurosurgery, Catholic University of Rome, Rome, Italy
    Br J Neurosurg 26:284-6. 2012
    ..The diagnosis of embryonal tumour with abundant neuropil and true rosettes was posed...
  44. doi Vertex scalp mass as presenting sign of a complex intracranial vascular malformation
    Luca Massimi
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    J Neurosurg Pediatr 3:307-10. 2009
    ..The neuroimaging investigations pointed out a temporal AVM causing dilation of the intracranial sinuses and ectasia of the vein of the scalp; one of the veins was appreciable as a lump on the vertex...
  45. ncbi BaS analysis: a new cephalometric study for craniofacial malformations
    Sandro Pelo
    Maxillofacial Surgery, Catholic University Medical School, Via G Moscati 31 33, Rome 00168, Italy
    Childs Nerv Syst 25:997-1006. 2009
    ..The authors present a new cephalometric technique that could be used as a more objective mean of follow-up evaluation of patients undergoing craniofacial advancement...
  46. ncbi Cartilage differentiation in ependymoma: histogenetic considerations on a new case
    Antonella Coli
    Department of Anatomic Pathology, Catholic University, Largo F Vito 1, 00168, Rome, Italy
    Childs Nerv Syst 30:1301-5. 2014
    ..The immunohistochemical expression of fibronectin, tenascin-C, and CD44 was investigated, and the possible role of these molecules in the process of cartilage formation is discussed. Moreover, the literature on the subject is reviewed. ..
  47. ncbi Teaching NeuroImages: Postoperative bifocal stroke of the pontine tegmentum: Why don't you smile anymore?
    Paolo Frassanito
    From Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    Neurology 82:e165-6. 2014
    ..1) We hypothesized a mechanism of postoperative spasm of long circumferential branches of the basilar artery. This mechanism should be considered in cases of postoperative neurologic deficits with delayed onset.(2.) ..
  48. doi Epilepsy in Tuberous Sclerosis Complex
    Federica Novegno
    Department of Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    Adv Tech Stand Neurosurg 39:131-63. 2012
    ..There is also a section dedicated to the common association with cognitive impairment and the role of epilepsy control on its outcome...
  49. ncbi Vestibular evoked myogenic potentials in children affected by myelomeningocele
    Pasqualina M Picciotti
    Department of Otorhinolaryngology, Catholic University of the Sacred Heart, Rome, Italy
    Childs Nerv Syst 28:1761-5. 2012
    ..The aim of the present study is to establish if the vestibular evoked myogenic potentials (VEMPs) could be used as a clinical test for the evaluation of vestibular function in children affected by myelomeningocele (MMC)...
  50. doi Gene expression profiling in human craniosynostoses: a tool to investigate the molecular basis of suture ossification
    Camilla Bernardini
    Institute of Anatomy and Cell Biology, Universita Cattolica del Sacro Cuore, Largo F Vito, 1, 00168, Rome, Italy
    Childs Nerv Syst 28:1295-300. 2012
    ..A promising tool to investigate the molecular mechanisms that may orchestrate this event is the comparative analysis of suture- and synostosis-derived tissues and cells...
  51. doi Hydrocephalus and Chiari type I malformation
    Concezio Di Rocco
    Pediatric Neurosurgery, Catholic University Medical School, Policlinic A Gemelli, Largo Agostino Gemelli, 8, 00168 Rome, Italy
    Childs Nerv Syst 27:1653-64. 2011
    ..Hydrocephalus has been related to Chiari type I malformation (CIM) for a long time. The pathogenesis of this association is complex and still debated...
  52. doi Video-assisted microsurgical transoral approach to the craniovertebral junction: personal experience in childhood
    Massimiliano Visocchi
    Institute of Neurosurgery, Catholic University of Rome, Rome, Italy
    Childs Nerv Syst 27:825-31. 2011
    ..In particular we analyzed the opportunity for endoscopic video-assisted approach to the CVJ along with neuronavigation for anterior decompression by the transoral approach in paediatric patients...
  53. doi Cerebellar mutism after spontaneous intratumoral bleeding involving the upper cerebellar vermis: a contribution to the physiopathogenic interpretation
    Paolo Frassanito
    Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
    Childs Nerv Syst 25:7-11. 2009
    ..Transient mutism as a consequence of posterior fossa surgery is a well-known phenomenon. However, it has rarely been reported after focal nonsurgically induced cerebellar damage...
  54. pmc Ectopic immature renal tissue: clues for diagnosis and management
    Antonella Coli
    Department of Anatomic Pathology, Catholic University, Rome, Italy
    Int J Clin Exp Pathol 5:977-81. 2012
    ..From an extensive analysis of cases reported in literature we draw some practical suggestions for the diagnosis and treatment of this rare condition...
  55. ncbi Intracranial midline dermoid and epidermoid cysts in children
    Massimo Caldarelli
    Department of Pediatrics, Operative Unit of Pediatric Neurosurgery, Catholic University, Medical School, Rome, Italy
    J Neurosurg 100:473-80. 2004
    ..Authors of large series have only occasionally reported on pediatric cases, and these reports often lack a specific analysis of those cerebral midline lesions...
  56. pmc Hedgehog controls neural stem cells through p53-independent regulation of Nanog
    Agnese Po
    Department of Experimental Medicine, Sapienza University, Rome, Italy
    EMBO J 29:2646-58. 2010
    ..Our data reveal a mechanism for the function of Hh in the control of stemness that represents a crucial component of an integrated circuitry determining cell fate decision and involved in the maintenance of cancer SCs...
  57. doi Improvement of obstructive sleep apneas caused by hydrocephalus associated with Chiari malformation Type II following surgery
    Marco Luigetti
    Department of Neurosciences, Catholic University of Sacred Heart, Rome, Italy
    J Neurosurg Pediatr 6:336-9. 2010
    ..However, the striking improvement of symptoms after ventriculoatrial shunt placement suggested that hydrocephalus plays a major role in this condition. Assessment and effective treatment of SDB is crucial in the care of patients with CM...
  58. doi Unaffected motor cortex remodeling after hemispherectomy in an epileptic cerebral palsy patient. A TMS and fMRI study
    Fabio Pilato
    Institute of Neurology, Universita Cattolica, Largo A Gemelli 8, 00168 Rome, Italy
    Epilepsy Res 85:243-51. 2009
    ..Our findings demonstrate the feasibility of transcranial magnetic stimulation (TMS) and fMRI for predicting a post-surgical outcome and for evaluating functional cortical reorganization...
  59. doi Ollier disease
    Luca D'Angelo
    Paediatric Neurosurgical Unit, Catholic University of Rome, Rome, Italy
    Childs Nerv Syst 25:647-53. 2009
    ..The only effective treatment is represented by surgery that allows to resect the tumors and to treat their complications, such as pathological fractures, growth defect, and neurological symptoms...
  60. doi Recurrent tethered cord: radiological investigation and management
    Massimo Caldarelli
    Pediatric Neurosurgery, Catholic University Medical School, Largo A Gemelli, 8, 00168 Rome, Italy
    Childs Nerv Syst 29:1601-9. 2013
    ..The goal of this review is to provide information about the pathophysiology, the radiological picture, and the management of RTV according to the pertinent literature and the authors' experience...
  61. doi Sewing needles in the brain: infanticide attempts or accidental insertion?
    Carmelo Lucio Sturiale
    Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy
    Neurosurgery 67:E1170-9; discussion E1179. 2010
    ..In nonmedical literature, this practice was frequently described in Persian novels, and it has been thought that this ritual could have been diffused with the Persian Empire domination over the centuries...
  62. doi GDNF plasma levels in spina bifida: correlation with severity of spinal damage and motor function
    Antonio Chiaretti
    Pediatric Intensive Care Unit, Catholic University Medical School, Rome, Italy
    J Neurotrauma 25:1477-81. 2008
    ....
  63. doi Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation
    Caterina Cenci
    RNA editing Laboratory, Ospedale Pediatrico Bambino Gesu Research Institute, Piazza S Onofrio 4, 00165 Rome, Italy
    J Biol Chem 283:7251-60. 2008
    ..We show that elevated levels of ADAR1, as found in astrocytomas, do indeed interfere with ADAR2 specific editing activity. Furthermore, we show that the endogenous ADAR1 can form heterodimers with ADAR2 in astrocytes...