Marotta F, Yoshida C, Barreto R, Naito Y, Packer L. Oxidative-inflammatory damage in cirrhosis: effect of vitamin E and a fermented papaya preparation. J Gastroenterol Hepatol. 2007;22:697-703 pubmed
..05). Although the present data seem to suggest a potential supportive role of antioxidants/immunomodulators as FPP in HCV patients, more studies are needed to substantiate their effect on the natural history of the disease. ..
Marotta F, Naito Y, Bishier M, Jain S, Yadav H, Minelli E, et al
. Subclinical candiduria in patients with gastrointestinal malignancies: a preliminary study on the protective effect of a natural phytocompound. J Biol Regul Homeost Agents. 2010;24:317-24 pubmed
..A therapeutic approach with a natural antifungal phytocompound seems a safe and effective measure and a tentative prophylactic approach might also be envisaged...
Marotta F, Catanzaro R, Yadav H, Jain S, Tomella C, Polimeni A, et al
. Functional foods in genomic medicine: a review of fermented papaya preparation research progress. Acta Biomed. 2012;83:21-9 pubmed
Marotta F, Naito Y, Minelli E, Tajiri H, Bertuccelli J, Wu C, et al
. Chemopreventive effect of a probiotic preparation on the development of preneoplastic and neoplastic colonic lesions: an experimental study. Hepatogastroenterology. 2003;50:1914-8 pubmed
..has the potential to exert significant antimutagenic properties against colon cancer. ..
Marotta F, Barreto R, Wu C, Naito Y, Gelosa F, Lorenzetti A, et al
. Experimental acute alcohol pancreatitis-related liver damage and endotoxemia: synbiotics but not metronidazole have a protective effect. Chin J Dig Dis. 2005;6:193-7 pubmed
..Metronidazole did not produce such a beneficial effect; in fact, it further worsened liver damage when alcohol was added to the background of ongoing acute pancreatic inflammation. ..
Marotta F, Chui D, Lorenzetti A, Fayet F, Liu T, Marandola P. Muscular metabolism in aged rats under exhaustive exercise: effect of a modified alkaline supplementation. Rejuvenation Res. 2008;11:519-22 pubmed publisher
..05). This study suggests that MAS can improve fast and endurance muscle metabolism in aged rats by increasing cellular acetyl group availability and tricarboxylic acid turnover. ..
Marotta F, Pavasuthipaisit K, Yoshida C, Albergati F, Marandola P. Relationship between aging and susceptibility of erythrocytes to oxidative damage: in view of nutraceutical interventions. Rejuvenation Res. 2006;9:227-30 pubmed
..05). These preliminary data suggest that nutraceuticals with antioxidant/NO-regulating properties significantly protect from RBC oxidative damage, and are potential weapons for the aging process and chronic and degenerative diseases. ..
Marotta F, Weksler M, Naito Y, Yoshida C, Yoshioka M, Marandola P. Nutraceutical supplementation: effect of a fermented papaya preparation on redox status and DNA damage in healthy elderly individuals and relationship with GSTM1 genotype: a randomized, placebo-controlled, cross-over study. Ann N Y Acad Sci. 2006;1067:400-7 pubmed
Marotta F, Koike K, Lorenzetti A, Naito Y, Fayet F, Shimizu H, et al
. Nutraceutical strategy in aging: targeting heat shock protein and inflammatory profile through understanding interleukin-6 polymorphism. Ann N Y Acad Sci. 2007;1119:196-202 pubmed
..A nutraceutical intervention seems able to beneficially modulate such a phenomenon. ..