Emilio Marengo

Summary

Country: Italy

Publications

  1. ncbi 2D-PAGE maps analysis
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Alessandria, Italy
    Methods Mol Biol 428:291-325. 2008
  2. ncbi A new algorithm for the simulation of SDS 2D-PAGE datasets
    Emilio Marengo
    Department of Sciences and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy
    Methods Mol Biol 869:407-25. 2012
  3. ncbi GENOCOP algorithm and hierarchical grid transformation for image warping of two dimensional gel eletrophoretic maps
    Emilio Marengo
    Department of Science and Technological Innovation, University of Eastern Piedmont, viale Teresa Michel 11, 15121 Alessandria, Italy
    Mol Biosyst 8:975-84. 2012
  4. ncbi Development of a technique based on multi-spectral imaging for monitoring the conservation of cultural heritage objects
    Emilio Marengo
    University of Eastern Piedmont, Department of Environmental and Life Sciences, via T Michel 11, 15121 Alessandria, Italy
    Anal Chim Acta 706:229-37. 2011
  5. ncbi The principle of exhaustiveness versus the principle of parsimony: a new approach for the identification of biomarkers from proteomic spot volume datasets based on principal component analysis
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Viale T Michel 11, 15121, Alessandria, Italy
    Anal Bioanal Chem 397:25-41. 2010
  6. ncbi Use of Legendre moments for the fast comparison of two-dimensional polyacrylamide gel electrophoresis maps images
    Emilio Marengo
    Department of Life and Environmental Science, University of Eastern Piedmont, Via Bellini 25 G, 15100 Alessandria, Italy
    J Chromatogr A 1096:86-91. 2005
  7. ncbi Multivariate statistical tools applied to the characterization of the proteomic profiles of two human lymphoma cell lines by two-dimensional gel electrophoresis
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Alessandria, Italy
    Electrophoresis 27:484-94. 2006
  8. ncbi Modeling of the polluting emissions from a cement production plant by partial least-squares, principal component regression, and artificial neural networks
    Emilio Marengo
    Department of Environmental Sciences and Life, University of Eastern Piedmont, Via Bellini 25 G, 15100 Alessandria, Italy
    Environ Sci Technol 40:272-80. 2006
  9. ncbi Butene concentration prediction in ethylene/propylene/1-butene terpolymers by FT-IR spectroscopy through multivariate statistical analysis and artificial neural networks
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Alessandria, Italy
    Talanta 77:1111-9. 2009
  10. ncbi Application of partial least squares discriminant analysis and variable selection procedures: a 2D-PAGE proteomic study
    Emilio Marengo
    Dipartimento di Scienze dell Ambiente e della Vita, Universita degli Studi del Piemonte Orientale, Via Bellini 25 G, 15100, Alessandria, Italy
    Anal Bioanal Chem 390:1327-42. 2008

Collaborators

Detail Information

Publications39

  1. ncbi 2D-PAGE maps analysis
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Alessandria, Italy
    Methods Mol Biol 428:291-325. 2008
    ..The theoretical basis of each procedure is briefly introduced, together with a review of the most interesting applications present in recent literature...
  2. ncbi A new algorithm for the simulation of SDS 2D-PAGE datasets
    Emilio Marengo
    Department of Sciences and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy
    Methods Mol Biol 869:407-25. 2012
    ....
  3. ncbi GENOCOP algorithm and hierarchical grid transformation for image warping of two dimensional gel eletrophoretic maps
    Emilio Marengo
    Department of Science and Technological Innovation, University of Eastern Piedmont, viale Teresa Michel 11, 15121 Alessandria, Italy
    Mol Biosyst 8:975-84. 2012
    ..The optimal positions of the nodes of the grid can be successfully used for defining a good warping of the gels...
  4. ncbi Development of a technique based on multi-spectral imaging for monitoring the conservation of cultural heritage objects
    Emilio Marengo
    University of Eastern Piedmont, Department of Environmental and Life Sciences, via T Michel 11, 15121 Alessandria, Italy
    Anal Chim Acta 706:229-37. 2011
    ....
  5. ncbi The principle of exhaustiveness versus the principle of parsimony: a new approach for the identification of biomarkers from proteomic spot volume datasets based on principal component analysis
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Viale T Michel 11, 15121, Alessandria, Italy
    Anal Bioanal Chem 397:25-41. 2010
    ..The method is successfully applied to three different proteomic datasets to prove its effectiveness...
  6. ncbi Use of Legendre moments for the fast comparison of two-dimensional polyacrylamide gel electrophoresis maps images
    Emilio Marengo
    Department of Life and Environmental Science, University of Eastern Piedmont, Via Bellini 25 G, 15100 Alessandria, Italy
    J Chromatogr A 1096:86-91. 2005
    ..The results demonstrate that the Legendre moments can be successfully applied for fast classification purposes and similarity analysis...
  7. ncbi Multivariate statistical tools applied to the characterization of the proteomic profiles of two human lymphoma cell lines by two-dimensional gel electrophoresis
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Alessandria, Italy
    Electrophoresis 27:484-94. 2006
    ..It is thus suggested that, in future work in differential proteomic profiling, both univariate and multivariate statistical tools should be adopted...
  8. ncbi Modeling of the polluting emissions from a cement production plant by partial least-squares, principal component regression, and artificial neural networks
    Emilio Marengo
    Department of Environmental Sciences and Life, University of Eastern Piedmont, Via Bellini 25 G, 15100 Alessandria, Italy
    Environ Sci Technol 40:272-80. 2006
    ..This showed that it is possible to satisfactorily predict the two responses. Such a prediction will result in the prevention of environmental and legal problems connected to the polluting emissions...
  9. ncbi Butene concentration prediction in ethylene/propylene/1-butene terpolymers by FT-IR spectroscopy through multivariate statistical analysis and artificial neural networks
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Alessandria, Italy
    Talanta 77:1111-9. 2009
    ..The proposed approach allows the monitoring in real time of the polymer synthesis and the estimation of the characteristics of the product attainable from the concentration of 1-butene...
  10. ncbi Application of partial least squares discriminant analysis and variable selection procedures: a 2D-PAGE proteomic study
    Emilio Marengo
    Dipartimento di Scienze dell Ambiente e della Vita, Universita degli Studi del Piemonte Orientale, Via Bellini 25 G, 15100, Alessandria, Italy
    Anal Bioanal Chem 390:1327-42. 2008
    ..From this point of view, the multivariate procedure applied can be considered a good alternative to standard differential analysis, also taking into account the interdependencies existing among the variables...
  11. ncbi A new method of comparing 2D-PAGE maps based on the computation of Zernike moments and multivariate statistical tools
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Via Bellini 25 G, 15100, Alessandria, Italy
    Anal Bioanal Chem 391:1163-73. 2008
    ..The results demonstrate that the Zernike moments can be successfully applied for fast classification purposes. The final aim is to build models that can be used to achieve rapid diagnosis of these illnesses...
  12. ncbi A new algorithm for the simulation of sodium dodecil sulfate two-dimensional polyacrylamide gel electrophoresis data sets
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, viale Teresa Michel 11, Alessandria, Italy
    J Proteome Res 9:1864-72. 2010
    ....
  13. ncbi Investigation of the applicability of Zernike moments to the classification of SDS 2D-PAGE maps
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, viale Teresa Michel 11, 15121 Alessandria, Italy
    Anal Bioanal Chem 400:1419-31. 2011
    ....
  14. ncbi Technique based on LED multispectral imaging and multivariate analysis for monitoring the conservation state of the Dead Sea Scrolls
    Emilio Marengo
    Department of Environmental and Life Sciences, Universita del Piemonte Orientale, Viale T Michel 11, 15121 Alessandria, Italy
    Anal Chem 83:6609-18. 2011
    ..Results showed that we could detect and locate changing pixels, on the basis of reflectance changes, after only a few "hours" of aging...
  15. ncbi A new approach to the statistical treatment of 2D-maps in proteomics using fuzzy logic
    Emilio Marengo
    Dipartimento di Scienze e Tecnologie Avanzate Università del Piemonte Orientale Spalto Marengo 33 15100 Alessandria, Italy
    Ann Chim 93:105-16. 2003
    ..The effect of changing the standard deviation and the digitalisation resolution are investigated...
  16. ncbi A new integrated statistical approach to the diagnostic use of two-dimensional maps
    Emilio Marengo
    Dipartimento di Scienze e Tecnologie Avanzate, Universita del Piemonte Orientale, Alessandria, Italy
    Electrophoresis 24:225-36. 2003
    ..Multidimensional scaling allowed the separation of the two classes of samples without any misclassification...
  17. ncbi Optimisation of the formulation of a bubble bath by a chemometric approach market segmentation and optimisation
    Emilio Marengo
    Dipartimento di Scienze e Tecnologie Avanzate, Universita del Piemonte Orientale A Avogadro, Corso Borsalino 54, 15100 Alessandria, Italy
    Ann Chim 93:257-68. 2003
    ..The regression models allowed to identify the best formulations for the two segments ofthe market...
  18. ncbi Monitoring of an industrial process by multivariate control charts based on principal component analysis
    Emilio Marengo
    Dipartimento di Scienze e Tecnologie Avanzate, Universita del Piemonte Orientale, Spalto Marengo 33, 15100 Alessandria, Italy
    Ann Chim 93:525-38. 2003
    ..In spite of the successful identification of the presence of problems in the monitored process, the Smart chart did not allow an easy identification of the special causes of variation which casued the problems themselves...
  19. ncbi New approach based on fuzzy logic and principal component analysis for the classification of two-dimensional maps in health and disease. Application to lymphomas
    Emilio Marengo
    Dipartimento di Scienze e Tecnologie Avanzate, Universita del Piemonte Orientale, 15100 Alessandria, Italy
    J Chromatogr A 1004:13-28. 2003
    ..75 and 2.25. Principal component analysis and linear discriminant analysis allowed the separation of the two classes of samples without any misclassification...
  20. ncbi Application of three-way principal component analysis to the evaluation of two-dimensional maps in proteomics
    Emilio Marengo
    Dipartimento di Scienze e Tecnologie Avanzate, Universita del Piemonte Orientale, Spalto Marengo 33, 15100 Alessandria, Italy
    J Proteome Res 2:351-60. 2003
    ....
  21. ncbi Comparison of different calibration methods for the determination by FT-NIR spectroscopy of the hydroxyl number in polyester resins
    Emilio Marengo
    Universita del Piemonte Orientale Amedeo Avogadro, Dipartimento di Scienze e Tecnologie Avanzate, Spalto Marengo 33, 15100 Alessandria, Italy
    Ann Chim 94:219-28. 2004
    ..The linear methods (OLS-GEN, PLS and PCR) showed comparable results while artificial neural networks provided the best results both in fitting and prediction...
  22. ncbi Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Via Bellini 25 G, 15100 Alessandria, Italy
    J Proteome Res 7:2789-96. 2008
    ..The method successfully allowed the identification of the relevant spots from 2D maps...
  23. ncbi Numerical approaches for quantitative analysis of two-dimensional maps: a review of commercial software and home-made systems
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Alessandria, Italy
    Proteomics 5:654-66. 2005
    ..These statistical tools appear to perform well in differential proteomic studies...
  24. ncbi Identification of the regulatory proteins in human pancreatic cancers treated with Trichostatin A by 2D-PAGE maps and multivariate statistical analysis
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Spalto Marengo 33, 15100 Alessandria, Italy
    Anal Bioanal Chem 379:992-1003. 2004
    ..The treatment of both the cell lines with Trichostatin A therefore showed an appreciable effect on the proteomic pattern of the treated samples. Identification of some of the most relevant spots was also performed by mass spectrometry...
  25. ncbi Determination of perfluorochemicals in biological, environmental and food samples by an automated on-line solid phase extraction ultra high performance liquid chromatography tandem mass spectrometry method
    Fabio Gosetti
    University of Piemonte Orientale, DISAV Dipartimento di Scienze dell Ambiente e della Vita, Viale T Michel 11, 15121 Alessandria, Italy
    J Chromatogr A 1217:7864-72. 2010
    ..9%. In the whole, the results obtained for samples of river waters, blood serum, blood plasma, and fish confirm the ubiquitous presence of perfluorinated compounds, as recently denounced by many sources...
  26. ncbi Simultaneous determination of thirteen polycyclic aromatic hydrocarbons and twelve aldehydes in cooked food by an automated on-line solid phase extraction ultra high performance liquid chromatography tandem mass spectrometry
    Fabio Gosetti
    University of Piemonte Orientale, DISAV Dipartimento di Scienze dell Ambiente e della Vita, Viale T Michel 11, 15121 Alessandria, Italy
    J Chromatogr A 1218:6308-18. 2011
    ..R was shown not to depend on analyte concentration in the explored concentration range (LOQ - 50.000 μg L(-1)): the average R percent ranges from 70.6% to 120.0%...
  27. ncbi Study of proteomic changes associated with healthy and tumoral murine samples in neuroblastoma by principal component analysis and classification methods
    Emilio Marengo
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Spalto Marengo 33 15100 Alessandria, Italy
    Clin Chim Acta 345:55-67. 2004
    ..The adrenal gland is the election organ forming primary neuroblastoma (NB) tumours, the most common extracranial solid tumours of infancy and childhood...
  28. ncbi Development of a classification and ranking method for the identification of possible biomarkers in two-dimensional gel-electrophoresis based on principal component analysis and variable selection procedures
    Elisa Robotti
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Viale T Michel 11, 15121 Alessandria, Italy
    Mol Biosyst 7:677-86. 2011
    ..The method was applied to an artificial dataset and a real case-study: Ranking-PCA exhaustively identified the potential biomarkers and provided reliable and robust results...
  29. ncbi A new on-line solid phase extraction high performance liquid chromatography tandem mass spectrometry method to study the sun light photodegradation of mono-chloroanilines in river water
    Fabio Gosetti
    University of Piemonte Orientale, DISAV Dipartimento di Scienze dell Ambiente e della Vita, Viale T Michel 11, 15121 Alessandria, Italy
    J Chromatogr A 1217:3427-34. 2010
    ..Two photoproducts (aniline and 3-aminophenol), for which standards are available, have also been quantified...
  30. ncbi Monitoring of the surface of paper samples exposed to UV light by ATR-FT-IR spectroscopy and use of multivariate control charts
    Elisa Robotti
    Department of Environmental and Life Sciences, University of Eastern Piedmont, Via Bellini 25 G, Alessandria, Italy
    Anal Bioanal Chem 388:1249-63. 2007
    ..Finally, multivariate statistical tools were applied to the final dataset, coupled with construction of multivariate control charts, to identify the effects of UV light on the sample surfaces...
  31. ncbi Non-target screening of Allura Red AC photodegradation products in a beverage through ultra high performance liquid chromatography coupled with hybrid triple quadrupole/linear ion trap mass spectrometry
    Fabio Gosetti
    University of Piemonte Orientale, Dipartimento di Scienze e Innovazione Tecnologica DISIT, Viale T Michel 11, 15121 Alessandria, Italy Electronic address
    Food Chem 136:617-23. 2013
    ..The presence of aromatic amine or amide functionalities in the chemical structures proposed for the degradation products might suggest potential hazards to consumer health...
  32. ncbi Identification of photodegradation products of Allura Red AC (E129) in a beverage by ultra high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry
    Fabio Gosetti
    University of Piemonte Orientale, Department of Science and Technological Innovation, Viale T Michel 11, 15121 Alessandria, Italy
    Anal Chim Acta 746:84-9. 2012
    ..The presence of aromatic amine or amide groups in the chemical structures of the degradation products suggests the potential hazard for the consumer health...
  33. ncbi High-performance liquid chromatography-ultraviolet detection method for the simultaneous determination of typical biogenic amines and precursor amino acids. Applications in food chemistry
    Eleonora Mazzucco
    DISAV Dipartimento di Scienze dell Ambiente e della Vita, University of Piemonte Orientale Amedeo Avogadro, viale Teresa Michel 11, 15121 Alessandria, Italy
    J Agric Food Chem 58:127-34. 2010
    ..The results are discussed as a function of the total biogenic amine content and of the concentration ratio between amines and precursor amino acids...
  34. ncbi A traceability study on the Moscato wine chain
    Maurizio Aceto
    Universita del Piemonte Orientale, Dipartimento di Scienze e Innovazione Tecnologica, viale Michel 11, 15121 Alessandria, Italy Electronic address
    Food Chem 138:1914-22. 2013
    ....
  35. ncbi Iterative optimization of an ESI IT mass spectrometer using regular simplex and a multivariate target function representing the S/N ratio
    Elisa Robotti
    Department of Environmental and Life Sciences, University of Eastern Piedmont, viale Michel 11, 15121 Alessandria, Italy
    J Am Soc Mass Spectrom 22:118-29. 2011
    ....
  36. ncbi Chemometric investigations on environmental data from Carlo Alberto irrigation canal (Alessandria, Piedmont, Italy)
    Emilio Marengo
    Dipartimento di Scienze e Tecnologie Avanzate, Corso Borsalino, 54, 15100 Alessandria, Italy
    Ann Chim 92:541-50. 2002
    ..New samplings are now being performed and a larger set of environmental variables is determined on each sample...
  37. ncbi Simultaneous determination of sixteen underivatized biogenic amines in human urine by HPLC-MS/MS
    Fabio Gosetti
    Department of Science and Technological Innovation, University of Piemonte Orientale, Alessandria, Italy
    Anal Bioanal Chem 405:907-16. 2013
    ..9 to 100.0 %. Particular attention is devoted to the matrix effect and the correlated phenomena of ion enhancement or suppression in mass spectrometry detection...
  38. ncbi Classification of Nebbiolo-based wines from Piedmont (Italy) by means of solid-phase microextraction-gas chromatography-mass spectrometry of volatile compounds
    Emilio Marengo
    Department of Sciences and Advanced Technologies, University of East Piedmont, Alessandria, Italy
    J Chromatogr A 943:123-37. 2002
    ..A main factor, strictly connected to wine vintage, was identified and found to be related to some analytes...
  39. ncbi Cytotoxicity of cis-platinum(II) conjugate models. The effect of chelating arms and leaving groups on cytotoxicity: a quantitative structure-activity relationship approach
    Elena Monti
    Dipartimento di Biologia Strutturale e Funzionale, , via A. da Giussano 10, 21052 Busto Arsizio (VA, Italy
    J Med Chem 48:857-66. 2005
    ..6%, making it possible to discard 50% of the molecules from the test set following for cross-validation procedure. A four-variable regression model also proved effective in predicting the resistance index RI, Q2(LMO-50%) = 84.4%...