M E Mancuso

Summary

Country: Italy

Publications

  1. ncbi request reprint Interferon lambda 3 rs12979860 polymorphism in patients with haemophilia and HCV infection: a predictor of spontaneous viral clearance and sustained virological response
    Maria Elisa Mancuso
    Maria Elisa Mancuso, MD, PhD, Angelo Bianchi Bonomi Haemophilia and Thrombosis Center, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico, Via Pace 9, 20122 Milan, Italy, Tel 39 02 5503 4072, Fax 39 02 5503 2072, E mail
    Thromb Haemost 111:1067-76. 2014
  2. pmc Fc-fusion technology and recombinant FVIII and FIX in the management of the hemophilias
    Maria Elisa Mancuso
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy
    Drug Des Devel Ther 8:365-71. 2014
  3. doi request reprint Source and purity of factor VIII products as risk factors for inhibitor development in patients with hemophilia A
    M E Mancuso
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico and University of Milan, Milan, Italy
    J Thromb Haemost 10:781-90. 2012
  4. doi request reprint Arteriovenous fistula as stable venous access in children with severe haemophilia
    M E Mancuso
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Medicine and Medical Specialities, Milan, Italy
    Haemophilia 16:25-8. 2010
  5. doi request reprint Hepatitis C virus/human immunodeficiency virus coinfection in hemophiliacs: high rates of sustained virologic response to pegylated interferon and ribavirin therapy
    M E Mancuso
    Department of Medicine and Medical Specialities, Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, Milan, Italy
    J Thromb Haemost 7:1997-2005. 2009
  6. ncbi request reprint Radiosynoviorthesis in children with haemophilia
    G Pasta
    Traumatology Department and Angelo Bianchi Bonomi Haemophilia Centre, IRCCS Maggiore Hospital Foundation, Via Pace 9, 20122 Milano, Italy
    Hamostaseologie 29:S62-4. 2009
  7. doi request reprint Severe hemophilia with mild bleeding phenotype: molecular characterization and global coagulation profile
    E Santagostino
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Department of Medicine and Medical Specialties, IRCCS Ca Granda Foundation, Policlinico Maggiore Hospital, Luigi Villa Foundation and University of Milan, Milan, Italy
    J Thromb Haemost 8:737-43. 2010
  8. doi request reprint Prevention of arthropathy in haemophilia: prophylaxis
    E Santagostino
    Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre, Department of Internal Medicine and Medical Specialties, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation and University of Milan, Milan, Italy
    Haemophilia 14:16-9. 2008
  9. doi request reprint Haemophilia care in children--benefits of early prophylaxis for inhibitor prevention
    M E Mancuso
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, University of Milan, Milan, Italy
    Haemophilia 15:8-14. 2009
  10. doi request reprint Integrated postural analysis in children with haemophilia
    E Boccalandro
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Milan, Italy
    Haemophilia 20:263-7. 2014

Detail Information

Publications13

  1. ncbi request reprint Interferon lambda 3 rs12979860 polymorphism in patients with haemophilia and HCV infection: a predictor of spontaneous viral clearance and sustained virological response
    Maria Elisa Mancuso
    Maria Elisa Mancuso, MD, PhD, Angelo Bianchi Bonomi Haemophilia and Thrombosis Center, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico, Via Pace 9, 20122 Milan, Italy, Tel 39 02 5503 4072, Fax 39 02 5503 2072, E mail
    Thromb Haemost 111:1067-76. 2014
    ..001) and higher sustained response rates were observed in patients with the CC genotype who did not achieve rapid virological response (61% vs 30% in T allele patients; p=0.006). ..
  2. pmc Fc-fusion technology and recombinant FVIII and FIX in the management of the hemophilias
    Maria Elisa Mancuso
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy
    Drug Des Devel Ther 8:365-71. 2014
    ..Similar data have been obtained in the Phase III clinical studies with rFVIIIFc and rFIX-Fc published recently. Both drugs were satisfactorily safe, particularly with respect to immunogenicity, and no serious adverse event was observed...
  3. doi request reprint Source and purity of factor VIII products as risk factors for inhibitor development in patients with hemophilia A
    M E Mancuso
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico and University of Milan, Milan, Italy
    J Thromb Haemost 10:781-90. 2012
    ..Inhibitor development is influenced by several factors and the type of factor VIII (FVIII) products may play a role...
  4. doi request reprint Arteriovenous fistula as stable venous access in children with severe haemophilia
    M E Mancuso
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Medicine and Medical Specialities, Milan, Italy
    Haemophilia 16:25-8. 2010
    ..A regular follow-up is mandatory to allow early remedial interventions. Surgical AVF dismantlement is recommended as soon as transition to peripheral vein access is possible...
  5. doi request reprint Hepatitis C virus/human immunodeficiency virus coinfection in hemophiliacs: high rates of sustained virologic response to pegylated interferon and ribavirin therapy
    M E Mancuso
    Department of Medicine and Medical Specialities, Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, Milan, Italy
    J Thromb Haemost 7:1997-2005. 2009
    ..Nonetheless, in HCV-infected hemophiliacs, who are considered to constitute a difficult-to-treat population, current treatment strategies yielded rates of SVR similar to those obtained in non-hemophiliacs...
  6. ncbi request reprint Radiosynoviorthesis in children with haemophilia
    G Pasta
    Traumatology Department and Angelo Bianchi Bonomi Haemophilia Centre, IRCCS Maggiore Hospital Foundation, Via Pace 9, 20122 Milano, Italy
    Hamostaseologie 29:S62-4. 2009
    ..For all these reasons this procedure should be implemented and supported, particularly in developing countries...
  7. doi request reprint Severe hemophilia with mild bleeding phenotype: molecular characterization and global coagulation profile
    E Santagostino
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Department of Medicine and Medical Specialties, IRCCS Ca Granda Foundation, Policlinico Maggiore Hospital, Luigi Villa Foundation and University of Milan, Milan, Italy
    J Thromb Haemost 8:737-43. 2010
    ..Such global coagulation tests as thrombin generation assays are tools with which to investigate different coagulation profiles among severe hemophiliacs...
  8. doi request reprint Prevention of arthropathy in haemophilia: prophylaxis
    E Santagostino
    Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre, Department of Internal Medicine and Medical Specialties, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation and University of Milan, Milan, Italy
    Haemophilia 14:16-9. 2008
    ..The efficacy of primary prophylaxis was finally demonstrated also in the setting of a randomized clinical trial...
  9. doi request reprint Haemophilia care in children--benefits of early prophylaxis for inhibitor prevention
    M E Mancuso
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, University of Milan, Milan, Italy
    Haemophilia 15:8-14. 2009
    ..Practical approaches to early prophylaxis as implemented in the haemophilia centres in Milan and Bremen are discussed in this respect...
  10. doi request reprint Integrated postural analysis in children with haemophilia
    E Boccalandro
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Milan, Italy
    Haemophilia 20:263-7. 2014
    ....
  11. ncbi request reprint A prospective randomized trial of high and standard dosages of recombinant factor VIIa for treatment of hemarthroses in hemophiliacs with inhibitors
    E Santagostino
    Department of Internal Medicine and Dermatology, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation and University of Milan, Milan, Italy
    J Thromb Haemost 4:367-71. 2006
    ....
  12. doi request reprint Venous access in haemophilic children: choice and management
    E Santagostino
    Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Internal Medicine and Medical Specialties, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation and University of Milan, Milan, Italy
    Haemophilia 16:20-4. 2010
    ..More recently, arteriovenous fistula was shown to be a suitable alternative to CVADs because it is easy to use and is associated with a lower rate of complication...
  13. doi request reprint Synoviorthesis in haemophilia patients with inhibitors
    G Pasta
    Traumatology Department and Angelo Bianchi Bonomi Haemophilia Centre, IRCCS Maggiore Hospital Foundation, Milan, Italy
    Haemophilia 14:52-5. 2008
    ..For all these reasons this procedure should be implemented and supported, particularly in developing countries...