Ines Mancini

Summary

Country: Italy

Publications

  1. ncbi On the first polyarsenic organic compound from nature: arsenicin A from the New Caledonian marine sponge Echinochalina bargibanti
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita di Trento, I 38050 Povo Trento, Italy
    Chemistry 12:8989-94. 2006
  2. doi Temperature effect on the vibrational dynamics of cyclodextrin inclusion complexes: investigation by FTIR-ATR spectroscopy and numerical simulation
    Vincenza Crupi
    Dipartimento di Fisica, Universita degli Studi di Messina, CNISM, UdR Messina, C da Papardo, S ta Sperone 31, P O Box 55, 98166 S Agata, Messina, Italy
    J Phys Chem A 114:6811-7. 2010
  3. doi Synthesis and in-vitro cytotoxicity evaluation of novel naphtindolizinedione derivatives, part II: improved activity for aza-analogues
    Andrea Defant
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita degli Studi di Trento, Povo Trento, Italy
    Arch Pharm (Weinheim) 342:80-6. 2009
  4. doi Vibrational analysis as a powerful tool in structure elucidation of polyarsenicals: a DFT-based investigation of arsenicin A
    Graziano Guella
    Dipartimento di Fisica, Universita di Trento, Via Sommarive 14, 38050 Povo, Trento, Italy
    Phys Chem Chem Phys 11:2420-7. 2009
  5. ncbi Synthesis of marine natural products with antimalarial activity
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita di Trento, Povo Trento, Italy
    Mini Rev Med Chem 8:1265-84. 2008
  6. doi Fatty acid composition of common barbel (Barbus barbus) roe and evaluation of its haemolytic and cytotoxic activities
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita di Trento, Via Sommarive 14, I 38123 Povo Trento, Italy
    Toxicon 57:1017-22. 2011
  7. ncbi New 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidinium alkaloids (phloeodictynes) from the New Caledonian shallow-water haplosclerid sponge Oceanapia fistulosa. Structural elucidation from mainly LC-tandem-MS-soft-ionization techniques and discovery of antiplas
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Universita di Trento, I 38050 Povo Trento, Italy
    Org Biomol Chem 2:783-7. 2004
  8. ncbi Synthesis and bioactivity of linear oligomers related to polymeric alkylpyridinium metabolites from the Mediterranean sponge Reniera sarai
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Universita di Trento, Povo Trento, Italy
    Org Biomol Chem 2:1368-75. 2004
  9. ncbi Synthesis and in vitro cytotoxicity evaluation of novel naphthindolizinedione derivatives
    Andrea Defant
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita degli Studi di Trento, Trento, Italy
    Arch Pharm (Weinheim) 340:147-53. 2007
  10. ncbi Benzene-assisted atmospheric-pressure chemical ionization: a new liquid chromatography/mass spectrometry approach to the analysis of selected hydrophobic compounds
    Chiara Perazzolli
    Dipartimento di Fisica, Laboratorio di Chimica Bioorganica, Universita di Trento, 38050 Via Sommarive 14, Povo Trento, Italy
    Rapid Commun Mass Spectrom 19:461-9. 2005

Collaborators

Detail Information

Publications17

  1. ncbi On the first polyarsenic organic compound from nature: arsenicin A from the New Caledonian marine sponge Echinochalina bargibanti
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita di Trento, I 38050 Povo Trento, Italy
    Chemistry 12:8989-94. 2006
    ..Arsenicin A is endowed with potent bactericidal and fungicidal activities on human pathogenic strains. All this may revive pharmacological interest in arsenic compounds while prompting us to rethink the arsenic cycle in nature...
  2. doi Temperature effect on the vibrational dynamics of cyclodextrin inclusion complexes: investigation by FTIR-ATR spectroscopy and numerical simulation
    Vincenza Crupi
    Dipartimento di Fisica, Universita degli Studi di Messina, CNISM, UdR Messina, C da Papardo, S ta Sperone 31, P O Box 55, 98166 S Agata, Messina, Italy
    J Phys Chem A 114:6811-7. 2010
    ..By comparing these results, Me-beta-CD has been shown to be the most effective carrier for IBP...
  3. doi Synthesis and in-vitro cytotoxicity evaluation of novel naphtindolizinedione derivatives, part II: improved activity for aza-analogues
    Andrea Defant
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita degli Studi di Trento, Povo Trento, Italy
    Arch Pharm (Weinheim) 342:80-6. 2009
    ..Compound 14 is efficiently synthesized by aminolysis of the ester obtained as a single regio-isomer by an one-pot three-component procedure involving metal-assisted cyclization under microwave irradiation conditions...
  4. doi Vibrational analysis as a powerful tool in structure elucidation of polyarsenicals: a DFT-based investigation of arsenicin A
    Graziano Guella
    Dipartimento di Fisica, Universita di Trento, Via Sommarive 14, 38050 Povo, Trento, Italy
    Phys Chem Chem Phys 11:2420-7. 2009
    ....
  5. ncbi Synthesis of marine natural products with antimalarial activity
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita di Trento, Povo Trento, Italy
    Mini Rev Med Chem 8:1265-84. 2008
    ..Syntheses of the most promising molecules are summarized, with emphasis on structure-activity relationship (SAR) studies and their mechanism of action...
  6. doi Fatty acid composition of common barbel (Barbus barbus) roe and evaluation of its haemolytic and cytotoxic activities
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita di Trento, Via Sommarive 14, I 38123 Povo Trento, Italy
    Toxicon 57:1017-22. 2011
    ..Arachidonic acid (C20:4), docosahexaenoic acid (C22:6) and eicosapentaenoic acid (C20:5) proved to be the three most abundant members of a complex series of free fatty acids ranging from C14:0 to C24:5...
  7. ncbi New 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidinium alkaloids (phloeodictynes) from the New Caledonian shallow-water haplosclerid sponge Oceanapia fistulosa. Structural elucidation from mainly LC-tandem-MS-soft-ionization techniques and discovery of antiplas
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Universita di Trento, I 38050 Povo Trento, Italy
    Org Biomol Chem 2:783-7. 2004
    ..6 to 6 microM, while cytotoxicity against human A-549 cell line was low. This makes these alkaloids a good prospect as leads for novel antimalarial agents...
  8. ncbi Synthesis and bioactivity of linear oligomers related to polymeric alkylpyridinium metabolites from the Mediterranean sponge Reniera sarai
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Universita di Trento, Povo Trento, Italy
    Org Biomol Chem 2:1368-75. 2004
    ..Relatively high antibacterial and anti-acetylcholinesterase activities were observed that increase with higher degrees of oligomerization...
  9. ncbi Synthesis and in vitro cytotoxicity evaluation of novel naphthindolizinedione derivatives
    Andrea Defant
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita degli Studi di Trento, Trento, Italy
    Arch Pharm (Weinheim) 340:147-53. 2007
    ..Moreover, its cytotoxicity against the adriamicine-resistant breast tumour cell line at a concentration lower than 1 microM turned out to be higher than the values using the clinical anticancer agents, daunorubicin and mitoxantrone...
  10. ncbi Benzene-assisted atmospheric-pressure chemical ionization: a new liquid chromatography/mass spectrometry approach to the analysis of selected hydrophobic compounds
    Chiara Perazzolli
    Dipartimento di Fisica, Laboratorio di Chimica Bioorganica, Universita di Trento, 38050 Via Sommarive 14, Povo Trento, Italy
    Rapid Commun Mass Spectrom 19:461-9. 2005
    ..By using benzene as post-column reagent, positive ion mode detection was proven to be significantly enhanced as compared with APCI measurements carried out without benzene assistance...
  11. ncbi Calenzanane sesquiterpenes from the red seaweed Laurencia microcladia from the Bay of Calenzana, Elba Island: acid-catalyzed stereospecific conversion of calenzanol into indene- and guaiazulene-type sesquiterpenes
    Graziano Guella
    Laboratorio di Chimica Bioorganica, Universita di Trento, 38050 Povo Trento, Italy
    Chemistry 9:5770-7. 2003
    ..A unifying mechanistic view of these branching and cascade transformations may have both heuristic value, suggesting possible artefact origin of azulenoids, and synthetic applications...
  12. doi Bioactive poly(arsenic) compounds
    Ines Mancini
    Laboratorio di Chimica Bioorganica, Dipartimento di Fisica, Universita di Trento, Via Sommarive 14, 38123, Povo Trento, Italy
    Prog Mol Subcell Biol 54:175-95. 2013
    ....
  13. ncbi A new solution for an old problem: the regiochemical distribution of the acyl chains in galactolipids can be established by electrospray ionization tandem mass spectrometry
    Graziano Guella
    Laboratorio di Chimica Bioorganica, Facoltà di Scienze MFN, Universita di Trento, 38050 Povo Trento, Italy
    Rapid Commun Mass Spectrom 17:1982-94. 2003
    ..These results were validated by comparison with ESI-MS data obtained for the sn-2 lysoglyceroglycolipids synthesized via regiospecific enzymatic hydrolysis of the corresponding diacylglycerols by Rhizopus arrhizus lipase...
  14. ncbi Vibrational properties of inclusion complexes: the case of indomethacin-cyclodextrin
    Barbara Rossi
    Dipartimento di Fisica, Universita di Trento, 38050 Povo, Trento, Italy and INFM CRS SOFT, Universita di Roma La Sapienza, 00185 Roma, Italy
    J Chem Phys 125:44511. 2006
    ....
  15. pmc A comparative study of the actions of alkylpyridinium salts from a marine sponge and related synthetic compounds in rat cultured hippocampal neurones
    David J Koss
    School of Medical Sciences, College of Life Sciences and Medicine, Institute of Medical Science, The University of Aberdeen, Foresterhill, Aberdeen, Scotland, UK
    BMC Pharmacol 7:1. 2007
    ..Using electrophysiology, calcium imaging and 1,6-diphenyl-1,3,5-hexatriene imaging, the pore forming properties of poly-APS and four related synthetic oligomers have been tested on primary cultured rat hippocampal neurones...
  16. ncbi Antisettlement activity of synthetic analogues of polymeric 3-alkylpyridinium salts isolated from the sponge Reniera sarai
    Marco Faimali
    CNR Istituto di Scienze Marine ISMAR Sezione Tecnologie Marine, Genova, Italy
    Biofouling 21:49-57. 2005
    ..The compound 1,8-di(3-pyridyl)octane was the most efficient (EC50sett. = 0.44 microgml(-1)), although with a higher toxicity on naupliar stage of B. amphitrite than the natural polymers...
  17. ncbi Comparative antibacterial activity of polymeric 3-alkylpyridinium salts isolated from the Mediterranean sponge Reniera sarai and their synthetic analogues
    Elisabetta Chelossi
    Institute of Marine Sciences, Section of Marine Technologies, CNR, Via De Marini 6, 16149 Genoa, Italy
    Biomol Eng 23:317-23. 2006
    ....