M Maj

Summary

Country: Italy

Publications

  1. doi request reprint Validity and clinical utility of the current operational characterization of major depression
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Int Rev Psychiatry 24:530-7. 2012
  2. doi request reprint Development and validation of the current concept of major depression
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychopathology 45:135-46. 2012
  3. pmc Clinical decision making and outcome in routine care for people with severe mental illness (CEDAR): study protocol
    Bernd Puschner
    Department of Psychiatry and Psychotherapy II, Ulm University, Ludwig Heilmeyer Str 2, 89312 Günzburg, Germany
    BMC Psychiatry 10:90. 2010
  4. ncbi request reprint Diagnosis and treatment of rapidly cycling bipolar disorder
    M Maj
    Clinica Psichiatrica, Primo Policlinico Universitario, Napoli, Italy
    Eur Arch Psychiatry Clin Neurosci 251:II62-5. 2001
  5. ncbi request reprint Long-term outcome of lithium prophylaxis in bipolar disorder with mood-incongruent psychotic features: a prospective study
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, I 80138 Napoli, Italy
    J Affect Disord 71:195-8. 2002
  6. ncbi request reprint Agitated "unipolar" major depression: prevalence, phenomenology, and outcome
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Italy
    J Clin Psychiatry 67:712-9. 2006
  7. ncbi request reprint The prognostic significance of "switching" in patients with bipolar disorder: a 10-year prospective follow-up study
    Mario Maj
    Clinica Psichiatrica, Primo Policlinico Universitario, Largo Madonna delle Grazie, I 10138 Naples, Italy
    Am J Psychiatry 159:1711-7. 2002
  8. ncbi request reprint The effect of lithium in bipolar disorder: a review of recent research evidence
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Italy
    Bipolar Disord 5:180-8. 2003
  9. doi request reprint Financial and non-financial conflicts of interests in psychiatry
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Eur Arch Psychiatry Clin Neurosci 260:S147-51. 2010
  10. ncbi request reprint The impact of lithium prophylaxis on the course of bipolar disorder: a review of the research evidence
    M Maj
    Department of Psychiatry, University of Naples SUN, Italy
    Bipolar Disord 2:93-101. 2000

Detail Information

Publications109 found, 100 shown here

  1. doi request reprint Validity and clinical utility of the current operational characterization of major depression
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Int Rev Psychiatry 24:530-7. 2012
    ....
  2. doi request reprint Development and validation of the current concept of major depression
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychopathology 45:135-46. 2012
    ..This paper reviews the development and validation of the current concept of major depression and identifies priorities for future research...
  3. pmc Clinical decision making and outcome in routine care for people with severe mental illness (CEDAR): study protocol
    Bernd Puschner
    Department of Psychiatry and Psychotherapy II, Ulm University, Ludwig Heilmeyer Str 2, 89312 Günzburg, Germany
    BMC Psychiatry 10:90. 2010
    ..However, there is a lack of knowledge on CDM and its outcome in long-term illnesses, especially in care for people with severe mental illness...
  4. ncbi request reprint Diagnosis and treatment of rapidly cycling bipolar disorder
    M Maj
    Clinica Psichiatrica, Primo Policlinico Universitario, Napoli, Italy
    Eur Arch Psychiatry Clin Neurosci 251:II62-5. 2001
    ..One double-blind crossover study supports the clinical impression that the combination of at least two mood stabilizers may be needed in most rapid cyclers...
  5. ncbi request reprint Long-term outcome of lithium prophylaxis in bipolar disorder with mood-incongruent psychotic features: a prospective study
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, I 80138 Napoli, Italy
    J Affect Disord 71:195-8. 2002
    ..No study has assessed systematically up to now the long-term outcome of lithium prophylaxis in bipolar patients with vs. without mood-incongruent psychotic features...
  6. ncbi request reprint Agitated "unipolar" major depression: prevalence, phenomenology, and outcome
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Italy
    J Clin Psychiatry 67:712-9. 2006
    ....
  7. ncbi request reprint The prognostic significance of "switching" in patients with bipolar disorder: a 10-year prospective follow-up study
    Mario Maj
    Clinica Psichiatrica, Primo Policlinico Universitario, Largo Madonna delle Grazie, I 10138 Naples, Italy
    Am J Psychiatry 159:1711-7. 2002
    ..This study explored whether "switching" (i.e., the direct transition from one mood polarity to the other) has significant prognostic implications in patients with bipolar disorder...
  8. ncbi request reprint The effect of lithium in bipolar disorder: a review of recent research evidence
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Italy
    Bipolar Disord 5:180-8. 2003
    ..The recurrence risk is increased in the months following lithium discontinuation. Lithium seems to exert an antisuicidal effect in bipolar patients...
  9. doi request reprint Financial and non-financial conflicts of interests in psychiatry
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Eur Arch Psychiatry Clin Neurosci 260:S147-51. 2010
    ..Financial and non-financial conflicts of interests are widespread in psychiatric practice and research. They cannot be eradicated, but must be managed more effectively than is currently the case...
  10. ncbi request reprint The impact of lithium prophylaxis on the course of bipolar disorder: a review of the research evidence
    M Maj
    Department of Psychiatry, University of Naples SUN, Italy
    Bipolar Disord 2:93-101. 2000
    ....
  11. ncbi request reprint Agitated depression in bipolar I disorder: prevalence, phenomenology, and outcome
    Mario Maj
    Department of Psychiatry, University of Naples, Naples, Italy
    Am J Psychiatry 160:2134-40. 2003
    ..The study aimed to explore how prevalent agitated depression is in bipolar I disorder, whether it represents a mixed state, and whether it differs from nonagitated depression with respect to course and outcome...
  12. ncbi request reprint Phenomenology and prognostic significance of delusions in major depressive disorder: a 10-year prospective follow-up study
    Mario Maj
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    J Clin Psychiatry 68:1411-7. 2007
    ..The study explored the phenomenology and prognostic significance of delusions in major depressive disorder...
  13. ncbi request reprint Reliability and validity of four alternative definitions of rapid-cycling bipolar disorder
    M Maj
    Department of Psychiatry, University of Naples, Italy
    Am J Psychiatry 156:1421-4. 1999
    ..This study tested the reliability and validity of four definitions of rapid cycling...
  14. ncbi request reprint Circulating leptin in patients with anorexia nervosa, bulimia nervosa or binge-eating disorder: relationship to body weight, eating patterns, psychopathology and endocrine changes
    P Monteleone
    Institute of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138, Naples, Italy
    Psychiatry Res 94:121-9. 2000
    ....
  15. ncbi request reprint Neurocognitive functioning in subjects with eating disorders: the influence of neuroactive steroids
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Italy
    Biol Psychiatry 53:921-7. 2003
    ..Neuropsychological studies in subjects with eating disorders (EDs) have reported conflicting findings, which might be accounted for by several confounding variables, including neuroendocrine changes...
  16. ncbi request reprint Plamsa leptin response to acute fasting and refeeding in untreated women with bulimia nervosa
    P Monteleone
    Institute of Psychiatry, University of Naples SUN, Italy
    J Clin Endocrinol Metab 85:2499-503. 2000
    ..We conclude that in untreated women with BN, leptin, despite its very low plasma values, still holds its function as a sensor of body weight changes, but loses its role of signaling acute changes in energy balance...
  17. ncbi request reprint A multicenter Italian study of patients' relatives' beliefs about schizophrenia
    L Magliano
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, Italy
    Psychiatr Serv 52:1528-30. 2001
    ..The findings of this study may be useful for developing psychoeducational intervention and sensitization campaigns for the general population...
  18. ncbi request reprint The 3111T/C polymorphism of the CLOCK gene confers a predisposition to a lifetime lower body weight in patients with anorexia nervosa and bulimia nervosa: a preliminary study
    Alfonso Tortorella
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Am J Med Genet B Neuropsychiatr Genet 144:992-5. 2007
    ....
  19. ncbi request reprint Multilead quantitative EEG profile of clozapine in resting and vigilance-controlled conditions
    S Galderisi
    Department of Psychiatry, Medical School, University of Naples, Italy
    Psychiatry Res 67:113-22. 1996
    ..It is suggested that changes in the beta frequency range vary across subjects, whereas changes in slow and alpha activity are more consistent and critical for defining the QEEG profile of the drug...
  20. ncbi request reprint Long-term outcome of lithium prophylaxis in bipolar disorder: a 5-year prospective study of 402 patients at a lithium clinic
    M Maj
    Department of Psychiatry, First Medical School, University of Naples, Italy
    Am J Psychiatry 155:30-5. 1998
    ..In this prospective study, information was collected on all bipolar I patients who started lithium prophylaxis at a lithium clinic during more than 15 years...
  21. ncbi request reprint Plasma levels of neuroactive steroids are increased in untreated women with anorexia nervosa or bulimia nervosa
    P Monteleone
    Institute of Psychiatry, University of Naples SUN, Italy
    Psychosom Med 63:62-8. 2001
    ..Therefore, we measured plasma levels of DHEA, DHEA-S, 3alpha,5alpha-THP and other hormones in patients with AN or BN and explored possible relationships between neuroactive steroids and psychopathology...
  22. doi request reprint Different temperament and character dimensions correlate with panic disorder comorbidity in bipolar disorder and unipolar depression
    Marco Mula
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    J Anxiety Disord 22:1421-6. 2008
    ..This study aimed to investigate temperament and character correlates of panic disorder (PD) comorbidity in euthymic patients with bipolar disorder (BD) or unipolar depression (UD)...
  23. doi request reprint Decreased levels of serum brain-derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disorders
    P Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Bipolar Disord 10:95-100. 2008
    ....
  24. ncbi request reprint Olanzapine-induced weight gain in anorexia nervosa: involvement of leptin and ghrelin secretion?
    F Brambilla
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychoneuroendocrinology 32:402-6. 2007
    ..Aim of this study was to determine whether in patients with Anorexia Nervosa (AN) OLA induces weight gain through the modulation of the hunger-satiety regulatory peptides leptin and ghrelin...
  25. doi request reprint Neurocognitive functioning in bulimia nervosa: the role of neuroendocrine, personality and clinical aspects
    S Galderisi
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychol Med 41:839-48. 2011
    ....
  26. ncbi request reprint Plasma concentrations of amino acids in chronic schizophrenics treated with clozapine
    A Tortorella
    Institute of Psychiatry, University of Naples SUN, Naples, Italy
    Neuropsychobiology 44:167-71. 2001
    ..These data show changes in serum amino acids that may influence central serotonergic, dopaminergic and glutamatergic transmission in neuroleptic-resistant schizophrenics...
  27. ncbi request reprint Psychological consequences of the 1998 landslide in Sarno, Italy: a community study
    F Catapano
    Department of Psychiatry, University of Naples SUN, Largo Madonna della Grazie, 80138 Naples, Italy
    Acta Psychiatr Scand 104:438-42. 2001
    ..CONCLUSION: This study emphasizes the negative impact of a natural catastrophic event on mental health, and the need for preventive interventions...
  28. ncbi request reprint Insight and resistance in patients with obsessive-compulsive disorder
    F Catapano
    Department of Psychiatry, First Medical School, University of Naples, Italy
    Psychopathology 34:62-8. 2001
    ..These results suggest the utility of the assessment of insight and resistance in obsessive-compulsive patients, also for the prediction of response to treatment with SRIs...
  29. ncbi request reprint Patient functioning and family burden in a controlled, real-world trial of family psychoeducation for schizophrenia
    Lorenza Magliano
    Department of Psychiatry, Second University of Naples SUN, Largo Madonna delle Grazie, Naples I 80138, Italy lorenza
    Psychiatr Serv 57:1784-91. 2006
    ..This study explored the effectiveness of a psychoeducational family intervention for schizophrenia on patients' personal and social functioning as well as on relatives' burden and perceived support...
  30. doi request reprint Asymmetry of salivary cortisol and α-amylase responses to psychosocial stress in anorexia nervosa but not in bulimia nervosa
    P Monteleone
    Department of Psychiatry, University of Naples SUN, Italy
    Psychol Med 41:1963-9. 2011
    ..Therefore, we assessed salivary cortisol and α-amylase responses to the Trier Social Stress Test (TSST) in symptomatic patients with AN and BN compared to healthy controls...
  31. ncbi request reprint Brain electrical microstates in subjects with panic disorder
    S Galderisi
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Brain Res Bull 54:427-35. 2001
    ..Topographical abnormalities found for the LPC microstate in the LC were associated with a higher number of panic attacks, suggesting a pathogenetic role of the right temporo-hippocampal dysfunction in PD...
  32. ncbi request reprint Interleukin-1beta and tumor necrosis factor-alpha in children with major depressive disorder or dysthymia
    F Brambilla
    Clinica Psichiatrica dell Università, SUN, Naples, Italy
    J Affect Disord 78:273-7. 2004
    ..The aim of our study was to see whether or not cytokine secretion is impaired at a very young phase of development of depressive disorders, possibly being pathogenetically involved in their course...
  33. doi request reprint Deficit schizophrenia: an overview of clinical, biological and treatment aspects
    S Galderisi
    Department of Psychiatry, Medical School, University of Naples SUN, Largo Madonna delle Grazie, Naples, Italy
    Eur Psychiatry 24:493-500. 2009
    ..Two decades of research on deficit schizophrenia have failed to prove that it represents the extreme end of a severity continuum in schizophrenia, while some findings support the claim that it may be a separate disease entity...
  34. ncbi request reprint 'Simple schizophrenia': a controlled MRI and clinical/neuropsychological study
    S Galderisi
    Department of Psychiatry, Medical School, University of Naples SUN, Italy
    Psychiatry Res 91:175-84. 1999
    ..Patients with simple schizophrenia, as compared to those with other schizophrenia subtypes, presented a higher frequency of soft neurological signs and a greater impairment of social relationships...
  35. ncbi request reprint Aggressive behavioral characteristics and endogenous hormones in women with Bulimia nervosa
    P Cotrufo
    Institute of Psychiatry, University of Naples SUN, Naples, Italy
    Neuropsychobiology 42:58-61. 2000
    ..These findings suggest that in BN, increased plasma levels of testosterone may play a role in the modulation of aggressiveness...
  36. ncbi request reprint Opposite modifications in circulating leptin and soluble leptin receptor across the eating disorder spectrum
    P Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Mol Psychiatry 7:641-6. 2002
    ..The relevance of these findings to the pathophysiology and treatment of eating disorders remains to be elucidated...
  37. ncbi request reprint No association of the Arg51Gln and Leu72Met polymorphisms of the ghrelin gene with anorexia nervosa or bulimia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Neurosci Lett 398:325-7. 2006
    ..These results suggest that the Arg51Gln and the Leu72Met polymorphisms of the human ghrelin gene do not contribute to the genetic susceptibility to AN and BN...
  38. ncbi request reprint The 196G/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Italy
    Neurosci Lett 406:133-7. 2006
    ..These results suggest that the 196G/A SNP of the human BDNF gene does not contribute to the genetic susceptibility to BN and BED, but may predispose those patients to a more severe binge eating behavior...
  39. doi request reprint Investigation of 3111T/C polymorphism of the CLOCK gene in obese individuals with or without binge eating disorder: association with higher body mass index
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Neurosci Lett 435:30-3. 2008
    ..Present findings show for the first time that the 3111T/C SNP of the CLOCK gene is not associated to human obesity and/or BED, but it seems to predispose obese individuals to a higher BMI...
  40. ncbi request reprint The Leu72Met polymorphism of the ghrelin gene is significantly associated with binge eating disorder
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychiatr Genet 17:13-6. 2007
    ..Genes involved in the ghrelin physiology may therefore contribute to the biological vulnerability to binge eating disorder...
  41. ncbi request reprint Double dissociation of N1 and P3 abnormalities in deficit and nondeficit schizophrenia
    Armida Mucci
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Schizophr Res 92:252-61. 2007
    ..The N1 was affected in DS but not in NDS patients, whereas P3 was affected in NDS only. This double dissociation is consistent with the hypothesis that DS represents a separate disease entity within schizophrenia...
  42. pmc Patterns of structural MRI abnormalities in deficit and nondeficit schizophrenia
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Schizophr Bull 34:393-401. 2008
    ..These findings do not support the hypothesis that DS is the extreme end of a severity continuum within schizophrenia...
  43. ncbi request reprint Association between A218C polymorphism of the tryptophan-hydroxylase-1 gene, harm avoidance and binge eating behavior in bulimia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Neurosci Lett 421:42-6. 2007
    ....
  44. doi request reprint Alexithymia and cognitive dysfunctions in patients with panic disorder
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychother Psychosom 77:182-8. 2008
    ....
  45. doi request reprint Deranged secretion of ghrelin and obestatin in the cephalic phase of vagal stimulation in women with anorexia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Biol Psychiatry 64:1005-8. 2008
    ..Therefore, we investigated the responses of ghrelin and its recently discovered sibling peptide obestatin to modified sham feeding (MSF) in both AN and healthy women...
  46. doi request reprint Investigation of factors associated to crossover from anorexia nervosa restricting type (ANR) and anorexia nervosa binge-purging type (ANBP) to bulimia nervosa and comparison of bulimia nervosa patients with or without previous ANR or ANBP
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, 80138 Naples, Italy
    Compr Psychiatry 52:56-62. 2011
    ....
  47. doi request reprint Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359G/A CNR1 polymorphism is associated with antipsychotic-induced weight gain
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    J Clin Psychopharmacol 30:441-5. 2010
    ..Present findings, although obtained in a small population and in a naturalistic setting, suggest that the cDNA 385C/A SNP of the FAAH gene may predispose subjects to get a clinically meaningful weight gain after antipsychotic exposure...
  48. doi request reprint Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms in bipolar disorder and major depression
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Pharmacol Res 61:400-4. 2010
    ..These findings, although preliminary, suggest that the CNR1 1359 G/A and the FAAH cDNA 385C to A gene variants may contribute to the susceptibility to mood disorders...
  49. doi request reprint Management of schizophrenia with obesity, metabolic, and endocrinological disorders
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Largo Madonna delle Grazie, 80138, Napoli, Italy
    Psychiatr Clin North Am 32:775-94. 2009
    ..Psychiatrists should be aware of metabolic and endocrine side effects of antipsychotics and should make every effort to prevent or minimize them to improve the patients' compliance and quality of life...
  50. doi request reprint Social skills and neurocognitive individualized training in schizophrenia: comparison with structured leisure activities
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138, Naples, Italy
    Eur Arch Psychiatry Clin Neurosci 260:305-15. 2010
    ....
  51. doi request reprint Glucagon-like peptide-1 secretion in bulimia nervosa
    Francesca Brambilla
    Department of Mental Health, Naples University SUN, Largo Madonna delle Grazie, Naples 80138, Italy
    Psychiatry Res 169:82-5. 2009
    ..GLP-1 levels correlated positively with bingeing-vomiting frequency, with B.I.T.E. scores and the "bulimia" subitem scores of the EDI-2 scale, and negatively with the "ascetism" subitem score of the same scale...
  52. doi request reprint Enhanced ghrelin secretion in the cephalic phase of food ingestion in women with bulimia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Psychoneuroendocrinology 35:284-8. 2010
    ....
  53. doi request reprint Genetic susceptibility to eating disorders: associated polymorphisms and pharmacogenetic suggestions
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Pharmacogenomics 9:1487-520. 2008
    ..Future studies should focus on more homogeneous subgroups, either relying on specific ED traits or identifying endophenotypes. This will be useful also for prevention and treatment of EDs...
  54. doi request reprint Plasma obestatin, ghrelin, and ghrelin/obestatin ratio are increased in underweight patients with anorexia nervosa but not in symptomatic patients with bulimia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples, Largo Madonna delle Grazie, 80138 Naples, Italy
    J Clin Endocrinol Metab 93:4418-21. 2008
    ....
  55. doi request reprint The circadian basis of mood disorders: recent developments and treatment implications
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Large Madonna delle Grazie, Naples, Italy
    Eur Neuropsychopharmacol 18:701-11. 2008
    ....
  56. doi request reprint Views of persons with schizophrenia on their own disorder: an Italian participatory study
    Lorenza Magliano
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, Naples, Italy
    Psychiatr Serv 59:795-9. 2008
    ..This study explored the views of 241 patients with schizophrenia about their own disorder...
  57. doi request reprint Neuroendocrine dysregulation of food intake in eating disorders
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Regul Pept 149:39-50. 2008
    ..Future studies should clarify whether neuroendocrine alterations are part of the genetically transmitted biological vulnerability to eating disorders...
  58. doi request reprint The cDNA 385C to A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) is associated with overweight/obesity but not with binge eating disorder in overweight/obese women
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Psychoneuroendocrinology 33:546-50. 2008
    ....
  59. ncbi request reprint Investigation of the serotonin transporter regulatory region polymorphism in bulimia nervosa: relationships to harm avoidance, nutritional parameters, and psychiatric comorbidity
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychosom Med 68:99-103. 2006
    ....
  60. ncbi request reprint Association of a functional serotonin transporter gene polymorphism with binge eating disorder
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Am J Med Genet B Neuropsychiatr Genet 141:7-9. 2006
    ..01, CI = 1.33-3.57). Although these data should be regarded as preliminary because of the small size of our sample, they suggest that the 5HTTPRL may contribute to the genetic susceptibility to BED...
  61. ncbi request reprint Hemispheric lateralization patterns and psychotic experiences in healthy subjects
    Armida Mucci
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Psychiatry Res 139:141-54. 2005
    ..Our results demonstrated gender-related differences in the pattern of hemispheric imbalance associated with psychotic experiences in healthy subjects...
  62. ncbi request reprint Family burden in long-term diseases: a comparative study in schizophrenia vs. physical disorders
    Lorenza Magliano
    Department of Psychiatry, University of Naples, Largo Madonna delle Grazie, I 80138 Naples, Italy
    Soc Sci Med 61:313-22. 2005
    ....
  63. ncbi request reprint Differential responses of circulating ghrelin to high-fat or high-carbohydrate meal in healthy women
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, 80138 Naples, Italy
    J Clin Endocrinol Metab 88:5510-4. 2003
    ..007). These findings show that circulating ghrelin is differently suppressed by diet manipulations. The mechanisms responsible for such a phenomenon and its possible implication in the physiology of human satiety remain to be elucidated...
  64. ncbi request reprint Leptin functioning in eating disorders
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    CNS Spectr 9:523-9. 2004
    ..However, malnutrition-induced alterations in its physiology may contribute to the genesis and/or the maintenance of some clinical manifestations of AN and BN and may have an impact on the prognosis of AN...
  65. ncbi request reprint Enhanced serum cholesterol and triglyceride levels in bulimia nervosa: relationships to psychiatric comorbidity, psychopathology and hormonal variables
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Psychiatry Res 134:267-73. 2005
    ..This alteration may be involved in the pathophysiology of certain psychopathological characteristics of BN and cannot be explained by the co-occurrence of other psychiatric disorders...
  66. ncbi request reprint Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary study
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    J Clin Psychopharmacol 24:437-40. 2004
    ....
  67. ncbi request reprint Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Neuropsychopharmacology 30:1216-21. 2005
    ....
  68. ncbi request reprint Opposite changes in the serum brain-derived neurotrophic factor in anorexia nervosa and obesity
    Palmiero Monteleone
    Department of Psychiatry, Institution University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Psychosom Med 66:744-8. 2004
    ..Therefore, the possibility exists that alterations in BDNF production and/or activity are involved in the pathophysiology of anorexia nervosa (AN) and obesity...
  69. ncbi request reprint Investigation of peptide YY and ghrelin responses to a test meal in bulimia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Biol Psychiatry 57:926-31. 2005
    ..Therefore, we aimed to assess plasma PYY and ghrelin responses to a test meal in symptomatic bulimics...
  70. ncbi request reprint Circulating ghrelin is decreased in non-obese and obese women with binge eating disorder as well as in obese non-binge eating women, but not in patients with bulimia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Psychoneuroendocrinology 30:243-50. 2005
    ..The reduction of plasma ghrelin in non-obese and obese binge eaters as well as in obese non-binge eaters may represent a secondary change aiming to counteract their positive energy imbalance...
  71. ncbi request reprint Is the time course of clozapine response correlated to the time course of clozapine plasma levels? A one-year prospective study in drug-resistant patients with schizophrenia
    Michele Fabrazzo
    Institute of Psychiatry, University of Naples SUN, Naples, Italy
    Neuropsychopharmacology 27:1050-5. 2002
    ..The present findings show, for the first time, that the time course of the clinical response to clozapine may be linked to the time course of plasma levels of clozapine and its major metabolites...
  72. ncbi request reprint Circulating brain-derived neurotrophic factor is decreased in women with anorexia and bulimia nervosa but not in women with binge-eating disorder: relationships to co-morbid depression, psychopathology and hormonal variables
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychol Med 35:897-905. 2005
    ..In the present study, we investigated serum levels of BDNF in patients with anorexia nervosa (AN), bulimia nervosa (BN) and binge-eating disorder (BED)...
  73. ncbi request reprint Historical, psychopathological, neurological, and neuropsychological aspects of deficit schizophrenia: a multicenter study
    Silvana Galderisi
    University of Naples Department of Psychiatry, Italy
    Am J Psychiatry 159:983-90. 2002
    ....
  74. ncbi request reprint Impaired reduction of enhanced levels of dehydroepiandrosterone by oral dexamethasone in anorexia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Psychoneuroendocrinology 31:537-42. 2006
    ..These data support the view that in AN, the increased production of DHEA may be linked to mechanisms other than the enhanced CRF/ACTH drive...
  75. ncbi request reprint Pronounced early increase in circulating leptin predicts a lower weight gain during clozapine treatment
    Palmiero Monteleone
    Institute of Psychiatry, University of Naples SUN, Naples, Italy
    J Clin Psychopharmacol 22:424-6. 2002
    ..These findings suggest that early changes in leptin secretion may predict long-term weight gain in the course of clozapine administration...
  76. ncbi request reprint Correlations between negative symptoms and peripheral G protein levels in mononuclear leukocytes of deficit and nondeficit schizophrenics. Preliminary results
    Palmiero Monteleone
    Department of Psychiatry, University of Naples S U N, Largo Madonna delle Grazie, 80138 Naples, Italy
    Eur Arch Psychiatry Clin Neurosci 252:214-8. 2002
    ..These results must be regarded as preliminary because of the possible interference of antipsychotic drugs on the explored parameters...
  77. ncbi request reprint Leptin secretion is related to chronicity and severity of the illness in bulimia nervosa
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychosom Med 64:874-9. 2002
    ....
  78. ncbi request reprint Subthreshold mania as predictor of depression during interferon treatment in HCV+ patients without current or lifetime psychiatric disorders
    Stefano Pini
    Department of Psychiatry, University of Pisa, Pisa, Italy
    J Psychosom Res 62:349-55. 2007
    ..We analyzed the impact of lifetime manic-hypomanic symptoms and anxiety on the development of depression in hepatitis-C-virus-infected subjects treated with two different types of IFN-alpha...
  79. ncbi request reprint Persistent amenorrhoea in weight-recovered anorexics: psychological and biological aspects
    Francesca Brambilla
    Istituto di Clinica Psichiatrica, Universita, SUN, Naples, Italy
    Psychiatry Res 118:249-57. 2003
    ....
  80. ncbi request reprint Circulating levels of neuroactive steroids in patients with binge eating disorder: a comparison with nonobese healthy controls and non-binge eating obese subjects
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Int J Eat Disord 34:432-40. 2003
    ..To assess whether those changes are related to malnutrition, we investigated plasma levels of neuroactive steroids in women with binge eating disorder (BED) who compulsively binge as bulimic patients, but do not incur malnutrition...
  81. ncbi request reprint Opposite changes in circulating adiponectin in women with bulimia nervosa or binge eating disorder
    Palmiero Monteleone
    Department of Psychiatry, University of Naples SUN, 80138 Naples, Italy
    J Clin Endocrinol Metab 88:5387-91. 2003
    ....
  82. ncbi request reprint Catechol-O-methyltransferase Val158Met polymorphism in schizophrenia: associations with cognitive and motor impairment
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Neuropsychobiology 52:83-9. 2005
    ..These results support the hypothesis that the COMT Val(158)Met polymorphism influences executive functions in schizophrenia and the neuromotor performance in the deficit subtype only...
  83. ncbi request reprint COMT Val(158)Met and BDNF C(270)T polymorphisms in schizophrenia: a case-control study
    Silvana Galderisi
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie 1, 80138 Naples, Italy
    Schizophr Res 73:27-30. 2005
    ..These results do not support the hypothesis that the COMT Val(158)Met or BDNF C(270)T gene polymorphisms are associated with liability to schizophrenia...
  84. ncbi request reprint Ghrelin and leptin responses to food ingestion in bulimia nervosa: implications for binge-eating and compensatory behaviours
    P Monteleone
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychol Med 33:1387-94. 2003
    ..In the present study, we investigated ghrelin and leptin responses to food ingestion in patients with bulimia nervosa...
  85. ncbi request reprint Qualitative MRI findings in patients with schizophrenia: a controlled study
    S Galderisi
    Department of Psychiatry, Medical School, University of Naples SUN, Largo Madonna delle Grazie, I 80138, Naples, Italy
    Psychiatry Res 98:117-26. 2000
    ..The association of LVE and third VE with a poor outcome indicates that qualitative MRI evaluation might be of clinical relevance...
  86. ncbi request reprint The cortical generators of P3a and P3b: a LORETA study
    U Volpe
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Brain Res Bull 73:220-30. 2007
    ..Our findings on cortical generators are in line with the hypothesis that P3a reflects the automatic allocation of attention, while P3b is related to the effortful processing of task-relevant events...
  87. doi request reprint Obsessive-compulsive disorder with poor insight: a three-year prospective study
    Francesco Catapano
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, I 80138 Naples, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 34:323-30. 2010
    ..Further research is needed to identify alternative strategies for the management of these patients...
  88. ncbi request reprint Melanocortin-4 receptor molecular scanning and pro-opiomelanocortin R236G variant screening in binge eating disorder
    Alfonso Tortorella
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Psychiatr Genet 15:161. 2005
  89. ncbi request reprint Perception of patients' unpredictability and beliefs on the causes and consequences of schizophrenia- a community survey
    Lorenza Magliano
    Department of Psychiatry, University of Naples, Largo Madonna delle Grazie, 80138, Naples, Italy
    Soc Psychiatry Psychiatr Epidemiol 39:410-6. 2004
    ....
  90. ncbi request reprint Obsessive-compulsive disorder: a 3-year prospective follow-up study of patients treated with serotonin reuptake inhibitors OCD follow-up study
    Francesco Catapano
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    J Psychiatr Res 40:502-10. 2006
    ..The development of alternative strategies is needed to improve the treatment approaches for treatment-resistant OCD patients...
  91. ncbi request reprint Intestinal permeability is decreased in anorexia nervosa
    P Monteleone
    Department of Psychiatry, University of Naples S U N, Naples, Italy
    Mol Psychiatry 9:76-80. 2004
    ..Since IP reflects the anatomo-functional status of intestinal mucosa, the present findings support the idea that changes in the anatomo-physiology of intestinal mucosa occur in anorexia nervosa...
  92. ncbi request reprint Neurocognitive indices of executive hypercontrol in obsessive-compulsive disorder
    P Bucci
    Department of Psychiatry, University of Naples SUN, Naples, Italy
    Acta Psychiatr Scand 115:380-7. 2007
    ....
  93. doi request reprint Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effects
    P Monteleone
    Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
    Genes Brain Behav 8:728-32. 2009
    ....
  94. ncbi request reprint The impact of professional and social network support on the burden of families of patients with schizophrenia in Italy
    L Magliano
    Department of Psychiatry, University of Naples SUN, Italy
    Acta Psychiatr Scand 106:291-8. 2002
    ....
  95. ncbi request reprint Altered immunoreactive levels of G proteins in peripheral mononuclear cells of patients with anorexia nervosa and bulimia nervosa
    P Monteleone
    Department of Psychiatry, University of Naples S U N, Naples, Italy
    Mol Psychiatry 8:680-4. 2003
    ..These findings, although obtained in peripheral blood cells, may suggest a derangement of G protein-mediated signal transduction in the pathophysiology of eating disorders...
  96. ncbi request reprint [Family psychoeducational interventions for schizophrenia in routine settings: impact on patients' clinical status and social functioning and on relatives' burden and resources]
    Lorenza Magliano
    Dipartimento di Psichiatria, Università di Napoli SUN, Napoli
    Epidemiol Psichiatr Soc 15:219-27. 2006
    ..This study explored the effectiveness of a psychoeducational family intervention for schizophrenia on patients' clinical status and disability and relatives' burden and perceived support...
  97. ncbi request reprint [Burden, attitudes and social support in the families of patients with long-term physical diseases]
    Lorenza Magliano
    Dipartimento di Psichiatria, Università di Napoli SUN, Napoli
    Epidemiol Psichiatr Soc 13:255-61. 2004
    ..To describe in a sample of 646 relatives of patients with physical long-term illnesses: a) the relatives' burden of care; b) the relatives' attitudes towards the patients; c) the social and professional support received by the families...
  98. ncbi request reprint Motion standstill leads to activation of inferior parietal lobe
    Andrea Federspiel
    Department of Psychiatric Neurophysiology, University Hospital of Clinical Psychiatry, Bern, Switzerland
    Hum Brain Mapp 27:340-9. 2006
    ..We interpret this observation as a manifestation of an orienting reaction in IPL towards stimulus motion that might be detected but not resolved by other motion-processing areas (i.e., MT/V5)...
  99. ncbi request reprint Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia
    Isabel Matias
    Endocannabinoid Research Group, Institute of Biomolecular Chemistry of the National Research Council, Via Campi Flegrei 34, 80078 Pozzuoli Naples, Italy
    J Clin Endocrinol Metab 91:3171-80. 2006
    ..Cannabinoid CB(1) receptor blockade decreases weight and hyperinsulinemia in obese animals and humans in a way greatly independent from food intake...
  100. ncbi request reprint Plasma leptin and antipsychotic-induced body weight gain
    Palmiero Monteleone
    Neuropsychopharmacology 30:1769; author reply 1770-1. 2005
  101. ncbi request reprint "Psychiatric comorbidity": an artefact of current diagnostic systems?
    Mario Maj
    Br J Psychiatry 186:182-4. 2005