Emilio Russo

Summary

Affiliation: Magna Graecia University
Country: Italy

Publications

  1. doi request reprint Lamotrigine positively affects the development of psychiatric comorbidity in epileptic animals, while psychiatric comorbidity aggravates seizures
    Emilio Russo
    Science of Health Department, School of Medicine, University of Catanzaro, Italy
    Epilepsy Behav 28:232-40. 2013
  2. doi request reprint mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy
    Emilio Russo
    Science of Health Department, School of Medicine, University Magna Graecia of Catanzaro, Viale Europa Germaneto, 88100 Catanzaro, Italy
    Neuropharmacology 69:25-36. 2013
  3. doi request reprint Protective activity of α-lactoalbumin (ALAC), a whey protein rich in tryptophan, in rodent models of epileptogenesis
    E Russo
    Science of Health Department, School of Medicine, University Magna Graecia of Catanzaro, Italy
    Neuroscience 226:282-8. 2012
  4. doi request reprint Ameliorating effects of aripiprazole on cognitive functions and depressive-like behavior in a genetic rat model of absence epilepsy and mild-depression comorbidity
    Emilio Russo
    Science of Health Department, School of Medicine, University Magna Graecia of Catanzaro, Via T Campanella, 115, 88100 Catanzaro, Italy
    Neuropharmacology 64:371-9. 2013
  5. doi request reprint Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity
    Emilio Russo
    Chair of Pharmacology, Department of Experimental and Clinical Medicine, School of Medicine, University of Catanzaro, Italy
    Behav Brain Res 225:373-6. 2011
  6. ncbi request reprint Amino acid levels in some brain areas of inducible nitric oxide synthase knock out mouse (iNOS-/-) before and after pentylenetetrazole kindling
    Grazia De Luca
    Department of Biochemical, Physiological and Nutritional Sciences, School of Medicine, University of Messina, Messina, Italy
    Pharmacol Biochem Behav 85:804-12. 2006
  7. ncbi request reprint Effects of non-competitive AMPA receptor antagonists injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy
    Rita Citraro
    Section of Pharmacology, Department of Experimental and Clinical Medicine, Faculty of Medicine and Surgery, University of Catanzaro, School of Medicine at Catanzaro, Policlinico Mater Domini, Via Tommaso Campanella, 115, 88100 Catanzaro, Italy
    Neuropharmacology 51:1058-67. 2006
  8. doi request reprint CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations
    Rita Citraro
    Chair of Pharmacology, Department of Health Science, School of Medicine and Surgery, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Epilepsy Res 106:74-82. 2013
  9. doi request reprint Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model
    Emilio Russo
    Department of Experimental and Clinical Medicine, School of Medicine, University of Catanzaro, Via T Campanella 115, Catanzaro, Italy
    Epilepsia 52:1341-50. 2011
  10. doi request reprint Enhancement of anti-absence effects of ethosuximide by low doses of a noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist in a genetic animal model of absence epilepsy
    Emilio Russo
    Chair of Pharmacology, Department of Experimental and Clinical Medicine, School of Medicine, University of Catanzaro, Catanzaro, Italy
    Epilepsy Behav 13:295-9. 2008

Collaborators

Detail Information

Publications39

  1. doi request reprint Lamotrigine positively affects the development of psychiatric comorbidity in epileptic animals, while psychiatric comorbidity aggravates seizures
    Emilio Russo
    Science of Health Department, School of Medicine, University of Catanzaro, Italy
    Epilepsy Behav 28:232-40. 2013
    ....
  2. doi request reprint mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy
    Emilio Russo
    Science of Health Department, School of Medicine, University Magna Graecia of Catanzaro, Viale Europa Germaneto, 88100 Catanzaro, Italy
    Neuropharmacology 69:25-36. 2013
    ..Our experiments here suggest new insights into this intriguing field, which deserves to be further explored. This article is part of the Special Issue entitled 'New Targets and Approaches to the Treatment of Epilepsy'...
  3. doi request reprint Protective activity of α-lactoalbumin (ALAC), a whey protein rich in tryptophan, in rodent models of epileptogenesis
    E Russo
    Science of Health Department, School of Medicine, University Magna Graecia of Catanzaro, Italy
    Neuroscience 226:282-8. 2012
    ..However, other mechanisms of action contributing to ALAC effects cannot be excluded...
  4. doi request reprint Ameliorating effects of aripiprazole on cognitive functions and depressive-like behavior in a genetic rat model of absence epilepsy and mild-depression comorbidity
    Emilio Russo
    Science of Health Department, School of Medicine, University Magna Graecia of Catanzaro, Via T Campanella, 115, 88100 Catanzaro, Italy
    Neuropharmacology 64:371-9. 2013
    ..This article is part of a Special Issue entitled 'Cognitive Enhancers'...
  5. doi request reprint Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity
    Emilio Russo
    Chair of Pharmacology, Department of Experimental and Clinical Medicine, School of Medicine, University of Catanzaro, Italy
    Behav Brain Res 225:373-6. 2011
    ....
  6. ncbi request reprint Amino acid levels in some brain areas of inducible nitric oxide synthase knock out mouse (iNOS-/-) before and after pentylenetetrazole kindling
    Grazia De Luca
    Department of Biochemical, Physiological and Nutritional Sciences, School of Medicine, University of Messina, Messina, Italy
    Pharmacol Biochem Behav 85:804-12. 2006
    ....
  7. ncbi request reprint Effects of non-competitive AMPA receptor antagonists injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy
    Rita Citraro
    Section of Pharmacology, Department of Experimental and Clinical Medicine, Faculty of Medicine and Surgery, University of Catanzaro, School of Medicine at Catanzaro, Policlinico Mater Domini, Via Tommaso Campanella, 115, 88100 Catanzaro, Italy
    Neuropharmacology 51:1058-67. 2006
    ..These findings suggest that AMPA receptor antagonists might play a role in absence epilepsies and that it might depend on the involvement of specific neuronal areas...
  8. doi request reprint CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations
    Rita Citraro
    Chair of Pharmacology, Department of Health Science, School of Medicine and Surgery, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Epilepsy Res 106:74-82. 2013
    ..In conclusion, our result might be useful for the identification of future drug therapies in absence epilepsy...
  9. doi request reprint Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model
    Emilio Russo
    Department of Experimental and Clinical Medicine, School of Medicine, University of Catanzaro, Via T Campanella 115, Catanzaro, Italy
    Epilepsia 52:1341-50. 2011
    ..Here, we examined the effects of long-term treatment with several AEDs on absence seizure development and onset of depressive-like behavior in WAG/Rij rats at different ages, using a forced swimming test (FST)...
  10. doi request reprint Enhancement of anti-absence effects of ethosuximide by low doses of a noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist in a genetic animal model of absence epilepsy
    Emilio Russo
    Chair of Pharmacology, Department of Experimental and Clinical Medicine, School of Medicine, University of Catanzaro, Catanzaro, Italy
    Epilepsy Behav 13:295-9. 2008
    ....
  11. doi request reprint Pharmacodynamic potentiation of antiepileptic drugs' effects by some HMG-CoA reductase inhibitors against audiogenic seizures in DBA/2 mice
    Emilio Russo
    Science of Health Department, Clinical Pharmacology Unit, School of Medicine, University Magna Graecia of Catanzaro, Viale Europa, Germaneto, 88100 Catanzaro, Italy
    Pharmacol Res 70:1-12. 2013
    ..The present results suggest that statins, besides the beneficial cardiovascular effects, might be able to affect brain areas, which might participate in the regulation of seizure susceptibility...
  12. doi request reprint Preclinical activity profile of α-lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy
    Rita Citraro
    Chair of Pharmacology, Department of Experimental and Clinical Medicine, School of Medicine, University Magna Graecia of Catanzaro, Via T Campanella 115, Catanzaro, Italy
    Epilepsy Res 95:60-9. 2011
    ..To evaluate the potential anticonvulsant activity of α-lactalbumin (ALAC), a whey protein rich in tryptophan (TRP) relative to other large neutral amino acids (LNAAs), in rodent models of seizures and epilepsy...
  13. ncbi request reprint Antiabsence effects of carbenoxolone in two genetic animal models of absence epilepsy (WAG/Rij rats and lh/lh mice)
    Pietro Gareri
    Section of Pharmacology, Department of Experimental and Clinical Medicine, Faculty of Medicine and Surgery, University of Catanzaro, Via T Campanella 115, 88100 Catanzaro, Italy
    Neuropharmacology 49:551-63. 2005
    ..No effects were observed in both animal models following systemic or focal administration of glycyrrhizin into the same brain areas where CBX was shown to be effective...
  14. doi request reprint Comparison of the antiepileptogenic effects of an early long-term treatment with ethosuximide or levetiracetam in a genetic animal model of absence epilepsy
    Emilio Russo
    Department of Experimental and Clinical Medicine, School of Medicine, University of Catanzaro, Catanzaro, Italy
    Epilepsia 51:1560-9. 2010
    ....
  15. ncbi request reprint Seizure susceptibility to various convulsant stimuli in dystrophin-deficient mdx mice
    Giovambattista De Sarro
    Department of Experimental and Clinical Medicine G Salvatore, School of Medicine, University Magna Graecia of Catanzaro, Policlinico Mater Domini, Via T Campanella, 115, 88100 Catanzaro, Italy
    Neurosci Res 50:37-44. 2004
    ..The present data suggests that the dystrophin deficiency in mdx mice affects the pathophysiology and pharmacology of acute and chronic epileptic seizures in an opposite manner...
  16. ncbi request reprint Comparative anticonvulsant activity of N-acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives in rodents
    Guido Ferreri
    Department of Experimental and Clinical Medicine, Faculty of Medicine and Surgery, School of Medicine at Catanzaro, University of Catanzaro, Policlinico Mater Domini, Via T Campanella, 115, 88100, Catanzaro, Italy
    Pharmacol Biochem Behav 77:85-94. 2004
    ....
  17. doi request reprint Huperzine a restores cortico-hippocampal functional connectivity after bilateral AMPA lesion of the nucleus basalis of meynert
    Vincenzo Rispoli
    Laboratory for Preclinical Researches in Neuropharmacology and Neurodegenerative Diseases, Department of Health Sciences, University Magna Graecia of Catanzaro, Italy
    J Alzheimers Dis 35:833-46. 2013
    ..In conclusion, the present results are in agreement with other experimental evidence that promote the clinical use of this natural drug...
  18. doi request reprint Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice
    Giovambattista De Sarro
    Clinical Pharmacology Unit, Science of Health Department, School of Medicine, University Magna Graecia of Catanzaro, Viale Europa, LocalitàGermaneto, 88100 Catanzaro, Italy
    Pharmacol Res 65:285-96. 2012
    ....
  19. ncbi request reprint Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy
    Emilio Russo
    Department of Experimental and Clinical Medicine G Salvatore, Faculty of Medicine and Surgery, University of Catanzaro Magna Graecia, School of Medicine, Catanzaro, Policlinico Mater Domini, 115 Via Tommaso Campanella, 88100 Catanzaro, Italy
    Neuropharmacology 46:865-78. 2004
    ..These results confirm TPM's broad spectrum of anticonvulsant activity and support the proposal that a modulation of neuronal L-type Ca(2+) channel activity plays an important role in its antiepileptic activity...
  20. doi request reprint Effects of ethanol on the development of genetically determined epilepsies in rats
    Emilio Russo
    Department of Experimental and Clinical Medicine, School of Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Int J Dev Neurosci 26:739-44. 2008
    ....
  21. ncbi request reprint Effects of some neurosteroids injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy
    Rita Citraro
    Section of Pharmacology, Department of Experimental and Clinical Medicine, Faculty of Medicine and Surgery, University of Catanzaro, Policlinico Mater Domini, Via T Campanella, 115, 88100 Catanzaro, Italy
    Neuropharmacology 50:1059-71. 2006
    ..These findings suggest that neurosteroids might play a role in absence epilepsies and that it might depend on the involvement of specific neuronal areas...
  22. ncbi request reprint Seizure susceptibility to various convulsant stimuli of knockout interleukin-6 mice
    Giovambattista De Sarro
    Department of Experimental and Clinical Medicine G Salvatore, School of Medicine, University of Catanzaro, Policlinico Mater Domini, Via T Campanella, 115, 88100 Catanzaro, Italy
    Pharmacol Biochem Behav 77:761-6. 2004
    ..The present data suggest that IL-6(-/-) mice might be a valid novel epileptic model for the study of pathophysiology and pharmacology of epileptic seizures...
  23. ncbi request reprint AMPA receptor antagonists as potential anticonvulsant drugs
    Giovambattista De Sarro
    Department of Experimental and Clinical Medicine, University of Catanzaro, Italy
    Curr Top Med Chem 5:31-42. 2005
    ..In particular, extensive work was addressed to the discovery of selective antagonists some of which proved to be potent anticonvulsant agents...
  24. ncbi request reprint Amino acid levels in some lethargic mouse brain areas before and after pentylenetetrazole kindling
    Grazia De Luca
    Department of Biochemical, Physiological and Nutritional Sciences, School of Medicine, University of Messina, AOU G Martino via Consolare Valeria, 98125 Messina, Italy
    Pharmacol Biochem Behav 81:47-53. 2005
    ..In conclusion, our results indicate that lethargic mice show a range of biochemical and behavioral changes, correlated in particular with a higher susceptibility to develop kindled seizures...
  25. ncbi request reprint Apomorphine-induced neurodegeneration in Mongolian gerbil hippocampus
    Emilio Russo
    Department of Experimental and Clinical Medicine, Faculty of Medicine and Surgery, University of Catanzaro, Catanzaro, Italy
    Schizophr Res 95:223-7. 2007
    ....
  26. doi request reprint New AMPA antagonists in epilepsy
    Emilio Russo
    University Magna Graecia of Catanzaro, School of Medicine, Science of Health Department, Catanzaro, Italy
    Expert Opin Investig Drugs 21:1371-89. 2012
    ..Evidences support their role during seizures and neurodegeneration. Development of AMPAR ligands has led to two different branches of research, with the identification of competitive and noncompetitive antagonists...
  27. ncbi request reprint Anticonvulsant effects of carbenoxolone in genetically epilepsy prone rats (GEPRs)
    Pietro Gareri
    Section of Pharmacology, Department of Experimental and Clinical Medicine, Faculty of Medicine and Surgery, University of Catanzaro, 88100 Catanzaro, Italy
    Neuropharmacology 47:1205-16. 2004
    ..No anticonvulsant effects were observed following focal bilateral microinjections of glycyrrhizin into the same brain areas where CBX was shown to be effective...
  28. doi request reprint Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy
    Rita Citraro
    Department of Health Science, School of Medicine and Surgery, University Magna Graecia of Catanzaro, Viale Europa Germaneto, 88100 Catanzaro, Italy
    Neuropharmacology 69:115-26. 2013
    ..This article is part of the Special Issue entitled 'New Targets and Approaches to the Treatment of Epilepsy'...
  29. doi request reprint The mTOR signaling pathway in the brain: focus on epilepsy and epileptogenesis
    Emilio Russo
    Science of Health Department, School of Medicine, University Magna Graecia of Catanzaro, Viale Europa, Germaneto, 88100 Catanzaro, Italy
    Mol Neurobiol 46:662-81. 2012
    ....
  30. ncbi request reprint The safety of clozapine in the elderly
    Pietro Gareri
    University Magna Graecia of Catanzaro, Mater Domini University Hospital, Clinical Pharmacology and Pharmacovigilance Unit, Faculty of Medicine and Surgery, Department of Experimental and Clinical Medicine, Catanzaro, Italy
    Expert Opin Drug Saf 7:525-38. 2008
    ..It is also effective for the treatment of aggressive behaviour in schizophrenic and demented patients and in the management of psychosis and aggression in Parkinson's disease and Lewy body dementia...
  31. doi request reprint Targeting α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors in epilepsy
    Rita Citraro
    University Magna Graecia of Catanzaro, School of Medicine, Science of Health Department, Catanzaro, Italy
    Expert Opin Ther Targets 18:319-34. 2014
    ..Glutamate activation of α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors (AMPARs) have long ago been identified as suitable targets for the development of anti seizure drugs...
  32. pmc Interactions among Low Dose of Methotrexate and Drugs Used in the Treatment of Rheumatoid Arthritis
    Marinella Patanè
    Department of Health Science, School of Medicine, University of Catanzaro, Viale Europa, 88100 Catanzaro, Italy Pharmacovigilance s Center Regione Calabria, University Hospital Mater Domini, 88100 Catanzaro, Italy
    Adv Pharmacol Sci 2013:313858. 2013
    ..In conclusion, during the treatment with MTX, DDIs play an important role in both the development of ADRs and therapeutic failure...
  33. pmc Pharmacovigilance and drug safety 2011 in Calabria (Italy): Adverse events analysis
    Francesca Scicchitano
    Department of Science of Health, School of Medicine, University of Catanzaro, Italy and Pharmacovigilance s Centre Calabria Region, University Hospital Mater Domini, Catanzaro, Italy
    J Res Med Sci 17:872-5. 2012
    ..The Italian Drug Agency (AIFA; Agenzia Italiana del Farmaco) is financing several projects to the aim of increasing reporting, and in Calabria a Pharmacovigilance Information Centre has been created...
  34. ncbi request reprint Sodium valproate induced tremor in a patient with epilepsy and Down's syndrome
    Antonio Siniscalchi
    Department of Neuroscience, Neurology Division, Annunziata Hospital, Cosenza, Italy
    Curr Drug Saf 8:69-71. 2013
    ....
  35. doi request reprint Tryptase-positive mast cells and angiogenesis in keloids: a new possible post-surgical target for prevention
    Michele Ammendola
    University of Catanzaro, Catanzaro, Italy
    Updates Surg 65:53-7. 2013
    ..In this context, several tryptase inhibitors might be clinically evaluated as a possible new anti-angiogenetic approach to prevent keloid formation after surgery...
  36. pmc Immunohistochemical analysis of the ubiquitin-conjugating enzyme UbcH10 in lung cancer: a useful tool for diagnosis and therapy
    Ida Perrotta
    Department of Ecology, University of Calabria, Rende, Italy
    J Histochem Cytochem 60:359-65. 2012
    ..The results suggest that UbcH10 might represent a new and promising diagnostic and prognostic marker in both histologic and cytologic specimens of lung cancer...
  37. doi request reprint Expression of tenascin-c and CD44 receptors in cardiac myxomas
    Giuseppe Donato
    Department of Pathology, School of Medicine, University Magna Graecia, Catanzaro, Italy
    Cardiovasc Pathol 18:173-7. 2009
    ..The expression of tenascin-c and hyaluran receptors in cardiac myxoma has never been investigated. Moreover, it is now well recognized that cells of cardiac myxoma differentiate along endothelial lines...
  38. ncbi request reprint Comparative anticonvulsant activity of some 2,3-benzodiazepine derivatives in rodents
    Giovambattista De Sarro
    Department of Experimental and Clinical Medicine, School of Medicine at Catanzaro, Policlinico Mater Domini, Via T Campanella, 115, 88100, Catanzaro, Italy
    Pharmacol Biochem Behav 74:595-602. 2003
    ....
  39. doi request reprint Phthalates: European regulation, chemistry, pharmacokinetic and related toxicity
    Pasquale Ventrice
    Chair of Pharmacology, Science of Health Department, School of Medicine, University of Catanzaro, Italy
    Environ Toxicol Pharmacol 36:88-96. 2013
    ..This article discusses the molecular and cellular mechanisms involved in organ toxicity of phthalates; furthermore, pharmacokinetic, chemistry and the European regulation are summarized...