Mercadante S, Ferrera P, Villari P, Casuccio A, Intravaia G, Mangione S. Frequency, indications, outcomes, and predictive factors of opioid switching in an acute palliative care unit. J Pain Symptom Manage. 2009;37:632-41 pubmed publisher
..The presence of both poor pain relief and adverse effects is a negative factor for switching prognosis, whereas renal failure is not. ..
Mercadante S, Ferrera P, Villari P. Is there a ceiling effect of transdermal buprenorphine? Preliminary data in cancer patients. Support Care Cancer. 2007;15:441-4 pubmed
..Further studies should clarify the role and the benefit of TD-BUP in specific clinical circumstances. ..
Mercadante S, Bruera E. Opioid switching in cancer pain: From the beginning to nowadays. Crit Rev Oncol Hematol. 2016;99:241-8 pubmed publisher