Research Topics
| Emiliano PavoniSummaryAffiliation: Kenton Labs Country: Italy Publications
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Detail Information
Publications
Identification of a panel of tumor-associated antigens from breast carcinoma cell lines, solid tumors and testis cDNA libraries displayed on lambda phageEmiliano Pavoni
Kenton Labs, c o Sigma Tau, Pomezia, Rome, Italy
BMC Cancer 4:78. 2004..Recent advances in molecular techniques have led to molecular definition of immunogenic tumor proteins based on their reactivity with autologous patient sera (SEREX)...
Selection, affinity maturation, and characterization of a human scFv antibody against CEA proteinEmiliano Pavoni
Kenton Labs, c o Sigma Tau, Via Pontina, km 30, 400, 00040 Pomezia RM, Italy
BMC Cancer 6:41. 2006..The selection and characterization of human anti-CEA single-chain antibody fragments (scFv) is a first step toward the construction of new anticancer monoclonal antibodies designed for optimal blood clearance and tumor penetration...
Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cellsEmiliano Pavoni
Kenton Srl, c o Sigma Tau SpA, Via Pontina, km 30, 400, 00040 Pomezia RM, Italy
BMC Biotechnol 7:70. 2007..In the present study, we analyzed the significance of local humoral response provided by tumor-infiltrating lymphocytes in breast cancer patients...
A study of the humoral immune response of breast cancer patients to a panel of human tumor antigens identified by phage displayEmiliano Pavoni
Kenton Labs, c/o Sigma-Tau, S.p.A, Via Pontina Km 30.400, Pomezia 00040, Rome, Italy
Cancer Detect Prev 30:248-56. 2006..001). CONCLUSIONS: Our data confirm association between breast cancer diagnosis of patients and presence in their peripheral blood of antibodies against several autoantigens identified by phage display...
Identification of tumor-associated antigens by screening phage-displayed human cDNA libraries with sera from tumor patientsOlga Minenkova
Kenton Labs, c o Sigma Tau, Pomezia Roma, Italy
Int J Cancer 106:534-44. 2003..Screening these phage-displayed libraries required limited amounts of sera from patients and efficiently identified several tumor antigens specifically reacting with sera from breast cancer patients...
Efficient display of scFv antibodies on bacteriophage lambdaPaola Vaccaro
Kenton Labs, c/o Sigma-Tau, Pomezia (Rome, Italy
J Immunol Methods 310:149-58. 2006....
New display vector reduces biological bias for expression of antibodies in E. coliEmiliano Pavoni
Kenton Labs, c o Sigma Tau, Via Pontina Km 30 400, Pomezia RM, 00040 Italy
Gene 391:120-9. 2007..The pKM19 plasmid facilitates an efficient maturation process, resulting in selection of antibodies with improved affinity without any stop codons...
Molecular dissection of the human B-cell response against Toxoplasma gondii infection by lambda display of cDNA librariesElisa Beghetto
Kenton Laboratories, Via Pontina Km 30.400, 00040 Rome, Italy
Int J Parasitol 33:163-73. 2003..gondii infection. These results demonstrate potential of lambda-display technology for antigen discovery and for the study of the human antibody response against infectious agents...
A novel approach for identification of tumor-associated antigens expressed on the surface of tumor cellsManlio Di Cristina
Kenton Laboratories, Via Pontina Km 30 400, 00040 Pomezia Rome, Italy
Int J Cancer 120:1293-303. 2007..The latter may represent novel tumor-specific targets...
