G Zifarelli

Summary

Affiliation: Istituto di Biofisica
Country: Italy

Publications

  1. doi request reprint CLC transport proteins in plants
    G Zifarelli
    Istituto di Biofisica, CNR, Via De Marini 6, I 16149 Genova, Italy
    FEBS Lett 584:2122-7. 2010
  2. pmc Extracellular determinants of anion discrimination of the Cl-/H+ antiporter protein CLC-5
    Silvia De Stefano
    Istituto di Biofisica, CNR, Via De Marini 6, I 16149 Genova, Italy
    J Biol Chem 286:44134-44. 2011
  3. pmc A single point mutation reveals gating of the human ClC-5 Cl-/H+ antiporter
    Silvia De Stefano
    G Zifarelli Istituto di Biofisica, CNR, Via De Marini 6, I 16149 Genova, Italy
    J Physiol 591:5879-93. 2013
  4. pmc Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels
    G Zifarelli
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Genova, Italy
    Br J Pharmacol 160:1652-61. 2010
  5. ncbi request reprint CLC chloride channels and transporters: a biophysical and physiological perspective
    G Zifarelli
    CNR, Istituto di Biofisica, Via De Marini 6, 16149 Genova, Italy
    Rev Physiol Biochem Pharmacol 158:23-76. 2007
  6. ncbi request reprint Channel or transporter? The CLC saga continues
    M Pusch
    Istituto di Biofisica, CNR, Via De Marini 6, I 16149 Genova, Italy
    Exp Physiol 91:149-52. 2006

Collaborators

Detail Information

Publications6

  1. doi request reprint CLC transport proteins in plants
    G Zifarelli
    Istituto di Biofisica, CNR, Via De Marini 6, I 16149 Genova, Italy
    FEBS Lett 584:2122-7. 2010
    ..Despite the different NO(3)(-) over Cl(-) selectivity of AtClC-a compared to the other CLC antiporters, it has similar transport properties. Other CLC homologues have been cloned in Arabidopsis, tobacco, rice and soybean...
  2. pmc Extracellular determinants of anion discrimination of the Cl-/H+ antiporter protein CLC-5
    Silvia De Stefano
    Istituto di Biofisica, CNR, Via De Marini 6, I 16149 Genova, Italy
    J Biol Chem 286:44134-44. 2011
    ..At saturating extracellular anion concentrations, neutralization of Lys210 is of little impact on the anion preference, suggesting an important role of Lys210 on the association rate of extracellular anions to Sext...
  3. pmc A single point mutation reveals gating of the human ClC-5 Cl-/H+ antiporter
    Silvia De Stefano
    G Zifarelli Istituto di Biofisica, CNR, Via De Marini 6, I 16149 Genova, Italy
    J Physiol 591:5879-93. 2013
    ..These results elucidate the biophysical properties of ClC-5 and contribute to the understanding of its physiological role. ..
  4. pmc Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels
    G Zifarelli
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Genova, Italy
    Br J Pharmacol 160:1652-61. 2010
    ..We attempted to identify the amino acids involved in the activation of ClC-Ka by NFA...
  5. ncbi request reprint CLC chloride channels and transporters: a biophysical and physiological perspective
    G Zifarelli
    CNR, Istituto di Biofisica, Via De Marini 6, 16149 Genova, Italy
    Rev Physiol Biochem Pharmacol 158:23-76. 2007
    ..The physiological significance of the Cl-/H+ antiport activity remains to be established...
  6. ncbi request reprint Channel or transporter? The CLC saga continues
    M Pusch
    Istituto di Biofisica, CNR, Via De Marini 6, I 16149 Genova, Italy
    Exp Physiol 91:149-52. 2006
    ..Apart from being useful biophysical tools, such drugs may provide a way to modulate protein function in vivo. With these tasks to be accomplished, it is definitely an exciting time in the chloride transport field...