Research Topics
Species | Alessandro ZerbiSummaryAffiliation: Istituto Clinico Humanitas Country: Italy Publications
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Detail Information
Publications
Surgical treatment of pancreatic endocrine tumours in Italy: results of a prospective multicentre study of 262 casesAlessandro Zerbi
Pancreatic Surgery Section, Humanitas Scientific Institute, Via Manzoni 56, Rozzano, Milan, Italy
Langenbecks Arch Surg 396:313-21. 2011..Information on the treatment of pancreatic endocrine tumours (PETs) comes mostly from small, retrospective, uncontrolled studies...
Adjuvant PEFG (cisplatin, epirubicin, 5-fluorouracil, gemcitabine) or gemcitabine followed by chemoradiation in pancreatic cancer: a randomized phase II trialMichele Reni
Department of Oncology, S Raffaele Scientific Institute, Milan, Italy
Ann Surg Oncol 19:2256-63. 2012..This randomized phase II trial aimed to identify the most promising regimen warranting phase III evaluation...
Final results of a prospective trial of a PEFG (Cisplatin, Epirubicin, 5-Fluorouracil, Gemcitabine) regimen followed by radiotherapy after curative surgery for pancreatic adenocarcinomaMichele Reni
Department of Radiochemotherapy, S Raffaele H Scientific Institute, Milan, Italy
Oncology 68:239-45. 2005..Postoperative management of patients with pancreatic adenocarcinoma (PA) is controversial...
Intraoperative ultrasound with contrast medium in resective pancreatic surgery: a pilot studyAntonino Spinelli
Unità Operativa e Cattedra di Chirurgia Generale, Universita degli Studi di Milano, Istituto Clinico Humanitas IRCCS, Via Alessandro Manzoni 56, 20089, Rozzano, Milan, Italy
World J Surg 35:2521-7. 2011..The purpose of the present study was to prospectively evaluate the possible role of contrast-enhanced intraoperative ultrasound (CEIOUS) during resective pancreatic surgery for primary lesion characterization and intraoperative staging...
Efficacy of an absorbable fibrin sealant patch (TachoSil) after distal pancreatectomy: a multicenter, randomized, controlled trialMarco Montorsi
Department of General Surgery, University of Milan, Istituto Clinico Humanitas IRCCS, Via Manzoni 56, Rozzano, Milan, Italy
Ann Surg 256:853-9; discussion 859-60. 2012..To evaluate the role of an absorbable fibrin sealant patch (TachoSil) in reducing postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP)...
Clinicopathological features of pancreatic endocrine tumors: a prospective multicenter study in Italy of 297 sporadic casesAlessandro Zerbi
Department of Surgery, Pancreas Unit, San Raffaele Scientific Institute, Milan, Italy
Am J Gastroenterol 105:1421-9. 2010..The aim of the study was to describe the clinical and pathological features of PETs in a prospective, multicenter study...
Carbohydrate antigen 19-9 change during chemotherapy for advanced pancreatic adenocarcinomaMichele Reni
Department of Oncology, S Raffaele Scientific Institute, Milan, Italy
Cancer 115:2630-9. 2009..The objective of this study was to evaluate the correlation between a decline in carbohydrate antigen 19-9 (CA 19-9) and survival in patients with advanced pancreatic cancer who received upfront chemotherapy...
Effect of surgeon volume on outcome following pancreaticoduodenectomy in a high-volume hospitalNicolò Pecorelli
Department of Surgery, San Raffaele Hospital, Vita Salute San Raffaele University, Via Olgettina 60, 20132, Milan, Italy
J Gastrointest Surg 16:518-23. 2012..The aim of this study is to assess the independent impact of surgeon volume on outcome after PD in a single high-volume institution...
The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinomaFederica Marchesi
Department of Immunology and Inflammation, IRCCS Clinical Institute Humanitas, Rozzano, Milano, Italy
Cancer Res 68:9060-9. 2008..Thus, the CX3CR1-CX3CL1 axis could represent a valuable therapeutic target to prevent tumor perineural dissemination in pancreatic cancer...
Pancreatic metastasis from renal cell carcinoma: which patients benefit from surgical resection?Alessandro Zerbi
Pancreas Unit, Department of Surgery, S Raffaele Scientific Institute, V Olgettina 60, 20132, Milan, Italy
Ann Surg Oncol 15:1161-8. 2008..Pancreas is a possible site of metastases from renal cell carcinoma (RCC). The aim of this study was to define the role of surgery in their treatment...
Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4Federica Marchesi
Department of Immunology and Cell Biology, Mario Negri Institute, Milan, Italy
Cancer Res 64:8420-7. 2004..CXCR4 not only stimulates cell motility and invasion but also promotes survival and proliferation. Strategies to target CXCR4 expressed on tumor cells may be of benefit in patients with pancreatic cancer...
Surgical management of acute pancreatitis in Italy: lessons from a prospective multicentre studyPaolo De Rai
Department of Surgery and Emergency Surgery, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Institute for Scientific Care and Treatment Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
HPB (Oxford) 12:597-604. 2010..This study aimed to evaluate the surgical treatment of acute pancreatitis in Italy and to assess compliance with international guidelines...
Intraductal papillary mucinous tumors of the pancreas: incidence, clinical findings and natural historyGianpaolo Balzano
Pancreas Unit, Department of Surgery, S. Raffaele Hospital, Milan, Italy
JOP 6:108-11. 2005
Irrelevance of microsatellite instability in the epidemiology of sporadic pancreatic ductal adenocarcinomaLuigi Laghi
Laboratory of Molecular Gastroenterology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy
PLoS ONE 7:e46002. 2012..Aims of the study were to determine the prevalence of MSI in surgically resected pancreatic cancers in a multicentric, retrospective study, and to assess the occurrence of pancreatic cancer in LS...
Gemcitabine versus cisplatin, epirubicin, fluorouracil, and gemcitabine in advanced pancreatic cancer: a randomised controlled multicentre phase III trialMichele Reni
Department of Radiochemotherapy, S Raffaele H Scientific Institute, Milan, Italy
Lancet Oncol 6:369-76. 2005..We aimed to assess whether a four-drug regimen could improve 4 month progression-free survival compared with gemcitabine alone...
Double self-expandable total-coated metal stent for gastrojejunal leak after pancreatoduodenectomyEnzo Masci
Division of Gastroenterology and Gastrointestinal Endoscopy, Vita-Salute San Raffaele University, Scientific Institute San Raffaele, Milan, Italy
Gastrointest Endosc 66:1024-5. 2007
Strategies for tumor immune escapeLorenzo Piemonti
Laboratory of Experimental Surgery, Department of Surgery II, Fondazione Centro S Raffaele del Monte Tabor, Milan, Italy
Drugs Today (Barc) 39:701-24. 2003..The purpose of this review is to evaluate the current status of knowledge concerning these different tumor-escape strategies...
Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancersLuigi Laghi
Division of Gastroenterology, Istituto Clinico Humanitas, Rozzano, Milan, 20089 Italy
Oncogene 21:4301-6. 2002..Results show that multiple K-RAS mutations are frequent both in PC with associated PanIN and in biliary cancers, and indicate that clonally distinct precursor lesions of PC might variably contribute to tumor development...
