M A Tabocchini

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. doi request reprint DNA and cellular effects of charged particles
    Maria Antonella Tabocchini
    Health and Technology Department, Istituto Superiore di Sanita, Roma, Italy
    Health Phys 103:547-55. 2012
  2. ncbi request reprint Induction and repair of DNA damage in human cells at different stages of differentiation
    M A Tabocchini
    Physics Laboratory, Istituto Superiore di Sanita, INFN Gr coll Sanità, Rome, Italy
    Radiat Prot Dosimetry 99:123-8. 2002
  3. doi request reprint DNA fragmentation induced in human fibroblasts by 56Fe ions: experimental data and Monte Carlo simulations
    A Campa
    Health and Technology Department, Istituto Superiore di Sanita, and INFN Sezione di Roma1, Gruppo Collegato Sanità, Roma, Italy
    Radiat Res 171:438-45. 2009
  4. ncbi request reprint DNA DSB induced by iron ions in human fibroblasts: LET dependence and shielding efficiency
    G Esposito
    Laboratorio di Fisica, Technology and Health Department, Istituto Superiore di Sanita, Rome, Italy
    Adv Space Res 35:243-8. 2005
  5. ncbi request reprint DNA fragments induction in human fibroblasts by radiations of different qualities
    G Esposito
    Health and Technology Department, Istituto Superiore di Sanita, Viale Regina Elena 299, Roma, Italy
    Radiat Prot Dosimetry 122:166-8. 2006
  6. ncbi request reprint DNA fragmentation induced in K562 cells by nitrogen ions
    M Belli
    Physics Laboratory, Istituto Superiore di Sanita, Rome, Italy
    Phys Med 17:219-21. 2001
  7. doi request reprint Adaptive response: modelling and experimental studies
    G Esposito
    Health and Technology Department, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy
    Radiat Prot Dosimetry 143:320-4. 2011
  8. ncbi request reprint DNA DSB induced in human cells by charged particles and gamma rays: experimental results and theoretical approaches
    A Campa
    Health and Technology Department, Istituto Superiore di Sanita, INFN Sezione di Roma1, Gruppo Collegato Sanità, Roma, Italy
    Int J Radiat Biol 81:841-54. 2005
  9. ncbi request reprint DNA fragmentation induced by Fe ions in human cells: shielding influence on spatially correlated damage
    F Antonelli
    Istituto Superiore di Sanita, Rome, Italy
    Adv Space Res 34:1353-7. 2004
  10. ncbi request reprint Mutation induction and RBE-LET relationship of low-energy protons in V79 cells
    M Belli
    Laboratorio di Fisica, Istituto Superiore di Sanita, Rome, Italy
    Int J Radiat Biol 59:459-65. 1991

Detail Information

Publications18

  1. doi request reprint DNA and cellular effects of charged particles
    Maria Antonella Tabocchini
    Health and Technology Department, Istituto Superiore di Sanita, Roma, Italy
    Health Phys 103:547-55. 2012
    ..Development of biophysical models aimed to describe the kinetics of the DNA repair process is underway, and it is expected to support the experimental investigation of the mechanisms underlying the cellular radiation response...
  2. ncbi request reprint Induction and repair of DNA damage in human cells at different stages of differentiation
    M A Tabocchini
    Physics Laboratory, Istituto Superiore di Sanita, INFN Gr coll Sanità, Rome, Italy
    Radiat Prot Dosimetry 99:123-8. 2002
    ..An overview is presented of these results together with preliminary data recently obtained on radiation induced DNA fragmentation as a function of radiation quality...
  3. doi request reprint DNA fragmentation induced in human fibroblasts by 56Fe ions: experimental data and Monte Carlo simulations
    A Campa
    Health and Technology Department, Istituto Superiore di Sanita, and INFN Sezione di Roma1, Gruppo Collegato Sanità, Roma, Italy
    Radiat Res 171:438-45. 2009
    ..The analysis performed with the GBS model proved to be quite sensitive to showing, with a phenomenological single parameter, variations in double-strand break (DSB) correlation...
  4. ncbi request reprint DNA DSB induced by iron ions in human fibroblasts: LET dependence and shielding efficiency
    G Esposito
    Laboratorio di Fisica, Technology and Health Department, Istituto Superiore di Sanita, Rome, Italy
    Adv Space Res 35:243-8. 2005
    ..Protection is only observed at high iron ions energy, especially at 5 GeV/u, where PMMA shield gives higher protection compared to Al or Pb shields of the same thickness expressed in g/cm2...
  5. ncbi request reprint DNA fragments induction in human fibroblasts by radiations of different qualities
    G Esposito
    Health and Technology Department, Istituto Superiore di Sanita, Viale Regina Elena 299, Roma, Italy
    Radiat Prot Dosimetry 122:166-8. 2006
    ..The highest yield was found for the 5 GeV u(-1) iron beam, that gave a value 30% higher than the 1 GeV u(-1) iron beam. A phenomenological method is used to parametrise deviation from randomness in fragment size spectra...
  6. ncbi request reprint DNA fragmentation induced in K562 cells by nitrogen ions
    M Belli
    Physics Laboratory, Istituto Superiore di Sanita, Rome, Italy
    Phys Med 17:219-21. 2001
    ..Comparison between gamma-rays and N-ions in AP cells shows that no significant differences are detected by the FAR analysis; otherwise fragmentation analysis demonstrates a higher effectiveness of nitrogen ions...
  7. doi request reprint Adaptive response: modelling and experimental studies
    G Esposito
    Health and Technology Department, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy
    Radiat Prot Dosimetry 143:320-4. 2011
    ..The results obtained after gamma irradiation suggest that cell density is a crucial factor for observing an AR...
  8. ncbi request reprint DNA DSB induced in human cells by charged particles and gamma rays: experimental results and theoretical approaches
    A Campa
    Health and Technology Department, Istituto Superiore di Sanita, INFN Sezione di Roma1, Gruppo Collegato Sanità, Roma, Italy
    Int J Radiat Biol 81:841-54. 2005
    ..To quantify the role played by radiation track structure and background fragments in modulating DNA fragmentation in human cells exposed to gamma-rays and light ions...
  9. ncbi request reprint DNA fragmentation induced by Fe ions in human cells: shielding influence on spatially correlated damage
    F Antonelli
    Istituto Superiore di Sanita, Rome, Italy
    Adv Space Res 34:1353-7. 2004
    ....
  10. ncbi request reprint Mutation induction and RBE-LET relationship of low-energy protons in V79 cells
    M Belli
    Laboratorio di Fisica, Istituto Superiore di Sanita, Rome, Italy
    Int J Radiat Biol 59:459-65. 1991
    ..0, 4.6 and 7.3 were obtained at the same LETs), and indicates that for mutation induction, also, the RBE-LET relationship may depend on the type of radiation...
  11. ncbi request reprint DNA fragmentation in V79 cells irradiated with light ions as measured by pulsed-field gel electrophoresis. II. Simulation with a generalized broken stick model
    A Campa
    Physics Laboratory, Istituto Superiore di Sanita, and INFN Sezione di Roma, Gruppo Collegato Sanità, Viale Regina Elena 299, I 00161 Rome, Italy
    Int J Radiat Biol 80:229-38. 2004
    ..To characterize the differences among the experimental DNA fragmentation spectra induced in Chinese hamster V79 cells by gamma-rays, low-energy protons and alpha-particles through the use of a phenomenological model...
  12. ncbi request reprint A 244Cm irradiator for protracted exposure of cultured Mammalian cells with alpha particles
    G Esposito
    Laboratorio di Fisica, Istituto Superiore di Sanita, Roma, Italy
    Health Phys 90:66-73. 2006
    ..69 x 10 Gy s(-1), with +12% and -8% variations at the center and the edge, respectively. The irradiator has been successfully tested and used for several experiments involving 16-d exposure of human fibroblasts monolayers...
  13. ncbi request reprint DNA fragmentation in V79 cells irradiated with light ions as measured by pulsed-field gel electrophoresis. I. Experimental results
    M Belli
    Physics Laboratory, Istituto Superiore di Sanita, Rome, Italy
    Int J Radiat Biol 78:475-82. 2002
    ..To compare the results on DNA fragmentation induced in Chinese hamster V79 cells by various doses of gamma-rays and low-energy protons and helium-4 ions...
  14. doi request reprint The Cosmic Silence experiment: on the putative adaptive role of environmental ionizing radiation
    M C Carbone
    Museo Storico della Fisica e Centro Studi e Ricerche Enrico Fermi, Rome, Italy
    Radiat Environ Biophys 48:189-96. 2009
    ..Our results are compatible with the hypothesis that ultra-low dose rate ionizing radiation, i.e. environmental radiation, may act as a conditioning agent in the radiation-induced adaptive response...
  15. ncbi request reprint Direct comparison of biological effectiveness of protons and alpha-particles of the same LET. II. Mutation induction at the HPRT locus in V79 cells
    M Belli
    Laboratorio di Fisica, Instituto Superiore di Sanita, Rome, Italy
    Int J Radiat Biol 61:625-9. 1992
    ..This finding is similar to, although slightly larger than, the factors 1.5-1.8 found for inactivation of the same cells in the same series of experiments...
  16. ncbi request reprint Influence of a low background radiation environment on biochemical and biological responses in V79 cells
    L Satta
    Energetics Department, Rome University La Sapienza, Via A Scarpa 14, 00161 Rome Italy
    Radiat Environ Biophys 41:217-24. 2002
    ..Overall, these data suggest a role of background ionizing radiation in determining an adaptive response, although they cannot be considered conclusive...
  17. ncbi request reprint DNA fragmentation in mammalian cells exposed to various light ions
    M Belli
    Istituto Superiore di Sanita and INFN-Gr. Coll. Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Adv Space Res 27:393-9. 2001
    ....
  18. ncbi request reprint Inactivation of human cells exposed to fractionated doses of low energy protons: relationship between cell sensitivity and recovery efficiency
    F Antonelli
    , Viale Regina Elena 299, I-00161 Roma, Italy
    J Radiat Res (Tokyo) 42:347-59. 2001
    ..These data show that radiosensitivity may not be related to a deficient recovery, and suggest a possible involvement of inducible repair mechanisms...