Research Topics
Genomes and Genes | Marco SilanoSummaryAffiliation: Istituto Superiore di Sanit Country: Italy Publications
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Detail Information
Publications
Early tissue transglutaminase-mediated response underlies K562(S)-cell gliadin-dependent agglutinationMarco Silano
Unit of Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy
Pediatr Res 71:532-8. 2012....
Effect of the timing of gluten introduction on the development of celiac diseaseMarco Silano
Unit of Human Nutrition and Health, Italian National Institute of Health, Viale Regina Elena 299, Rome, Italy
World J Gastroenterol 16:1939-42. 2010..Here, we present and review the most recent evidences regarding the effect of timing of gluten introduction during weaning, the amount of gluten introduced and simultaneous breastfeeding, on the development of CD...
Toxic, immunostimulatory and antagonist gluten peptides in celiac diseaseMarco Silano
Department of Food Sciences, Human Nutrition and Health, Istituto Superiore di Sanita, Roma, Italy
Curr Med Chem 16:1489-98. 2009....
The fifth anniversary of the European Food Safety Authority (EFSA): mission, organization, functioning and main resultsMarco Silano
Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Roma, Italy
Fitoterapia 79:149-60. 2008....
Effect of a gluten-free diet on the risk of enteropathy-associated T-cell lymphoma in celiac diseaseMarco Silano
Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
Dig Dis Sci 53:972-6. 2008..8 P = 0.01). These results show that a strict gluten-free diet is protective towards the development of enteropathy-associated T-cell lymphoma...
Avenins from different cultivars of oats elicit response by coeliac peripheral lymphocytesMarco Silano
Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy
Scand J Gastroenterol 42:1302-5. 2007..The aim of this work was to evaluate whether avenins from different varieties of oats show different abilities in the activation of coeliac peripheral lymphocytes...
In vitro tests indicate that certain varieties of oats may be harmful to patients with coeliac diseaseMarco Silano
Division of Food Science, Human Nutrition and Health, Higher Institute of Health, Rome, Italy
J Gastroenterol Hepatol 22:528-31. 2007..The presence of oats in gluten-free diet is controversial. The aim of this work is to evaluate if different varieties of oats exert different toxicity in coeliac disease...
Delayed diagnosis of coeliac disease increases cancer riskMarco Silano
Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, Italy
BMC Gastroenterol 7:8. 2007..The aim of this paper is to estimate the risk of developing a neoplasm among non diagnosed coeliac patients and to evaluate if this risk correlates with the age of patients at diagnosis of coeliac disease...
The new European legislation on traditional herbal medicines: main features and perspectivesMarco Silano
Department of Metabolism and Pathological Biochemistry, Istituto Superiore di Sanita, Rome, Italy
Fitoterapia 75:107-16. 2004....
Environmental factors of celiac disease: cytotoxicity of hulled wheat species Triticum monococcum, T. turgidum ssp. dicoccum and T. aestivum ssp. speltaOlimpia Vincentini
Division of Food Science, Human Nutrition and Health, National Institute of Health, Rome, Italy
J Gastroenterol Hepatol 22:1816-22. 2007..The purpose of this study was to investigate if species from ancient wheat could be considered as healthy food crops devoid or poor in cytotoxic prolamines for celiac disease...
A 10-residue peptide from durum wheat promotes a shift from a Th1-type response toward a Th2-type response in celiac diseaseMarco Silano
Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy
Am J Clin Nutr 87:415-23. 2008..Molecules able to shift the immune response from a Th1- to a Th2-type response have been suggested as therapeutic agents for Th1 autoimmune diseases...
Exogenous HIV-1 Nef upsets the IFN-γ-induced impairment of human intestinal epithelial integrityMaria Giovanna Quaranta
Department of Therapeutic Research and Medicine Evaluation, Istituto Superiore di Sanita, Roma, Italy
PLoS ONE 6:e23442. 2011..In the present study, we analyzed the effect of the accessory HIV-1 Nef protein on human epithelial cell line...
Antagonist peptides of the gliadin T-cell stimulatory sequences: a therapeutic strategy for celiac diseaseMarco Silano
Division of Food Sciences, Human Nutrition and Health, Istituto Superiore di Sanita, Viale Regina Elena, Roma, Italy
J Clin Gastroenterol 42:S191-2. 2008..These peptides have been obtained artificially by amino acids substitution of gliadin T-cell stimulatory sequences and an immunomodulatory sequence has been identified in the alcohol-soluble protein fraction of cultivars of durum wheat...
T-cell response to different cultivars of farro wheat, Triticum turgidum ssp. dicoccum, in celiac disease patientsOlimpia Vincentini
Division of Food Safety and Veterinary Public Health, National Institute of Health, Viale Regina Elena 299, Rome, Italy
Clin Nutr 28:272-7. 2009..dicoccum) with contrasting storage protein compositions...
A decapeptide from durum wheat prevents celiac peripheral blood lymphocytes from activation by gliadin peptidesMarco Silano
Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy 00161
Pediatr Res 61:67-71. 2007..These data indicate that a peptide naturally occurring in durum wheat exerts in vitro an antagonist effect against gliadin toxicity and could have a protective effect in CD disease...
Low-molecular-weight heparins induce decidual heparin-binding epidermal growth factor-like growth factor expression and promote survival of decidual cells undergoing apoptosisNicoletta Di Simone
Department of Obstetrics and Gynecology, Universita Cattolica del Sacro Cuore, Rome, Italy
Fertil Steril 97:169-77.e1. 2012..To evaluate the effects of low-molecular-weight heparins (LMWHs) on decidual heparin-binding epidermal growth factor-like growth factor (HB-EGF) expression/secretion and on TNF-α-induced decidual apoptosis...
Docosahexaenoic acid modulates in vitro the inflammation of celiac disease in intestinal epithelial cells via the inhibition of cPLA2Olimpia Vincentini
Unit of Human Nutrition and Health, Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanita, Viale Regina Elena, 299, 00161 Roma, Italy
Clin Nutr 30:541-6. 2011..The aims of the present work were to evaluate if: 1) intestinal epithelial cells have a role in the celiac inflammation, releasing AA, and 2) if DHA is able to modulate the celiac inflammation, down-regulating the release of AA...
Role of magnified ileoscopy in the diagnosis of cases of coeliac disease with predominant abdominal symptomsAntonello Trecca
Division of Operative Endoscopy and Gastroenterology, Fabio Di Giovambattista USI, Rome, Italy
Scand J Gastroenterol 44:320-4. 2009..This would be of clinical value in coeliac patients who show predominant abdominal symptoms and who undergo colonoscopy with ileoscopy as first clinical examination...
Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage via apoptosis in vitroNicoletta Di Simone
Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy
Am J Gastroenterol 105:2254-61. 2010..The aim of this study was to determine whether anti-tissue transglutaminase (anti-tTG) antibodies are involved in the damage of trophoblastic cells in vitro...
Clinical evolution of celiac disease in Italy 1982-2002Marco Silano
Department of Metabolism and Pathological Biochemistry, Istituto Superiore di Sanit, Roma, Italy
J Clin Gastroenterol 38:877-9. 2004..The relevance of the analysis is supported by the fact that Italy is one of the countries with the highest incidence of celiac disease. These findings underline the importance of a timely diagnosis of celiac disease...
Highly efficient gluten degradation by lactobacilli and fungal proteases during food processing: new perspectives for celiac diseaseCarlo G Rizzello
Department of Plant Protection and Applied Microbiology, University of Bari, Bari, Italy
Appl Environ Microbiol 73:4499-507. 2007..Bread making was standardized to show the suitability of the detoxified wheat flour. Food processing by selected sourdough lactobacilli and fungal proteases may be considered an efficient approach to eliminate gluten toxicity...
VSL#3 probiotic preparation has the capacity to hydrolyze gliadin polypeptides responsible for Celiac SprueMaria de Angelis
Department of Plant Protection and Applied Microbiology, University of Bari, 70126 Bari, Italy
Biochim Biophys Acta 1762:80-93. 2006..Proteolytic activity by probiotic VSL#3 may have an importance during food processing to produce pre-digested and tolerated gliadins for increasing the palatability of gluten-free products...
Prevention by a decapeptide from durum wheat of in vitro gliadin peptide-induced apoptosis in small-bowel mucosa from coeliac patientsMarco Silano
Scand J Gastroenterol 42:786-7. 2007
Pasta made from durum wheat semolina fermented with selected lactobacilli as a tool for a potential decrease of the gluten intoleranceRaffaella di Cagno
Department of Plant Protection and Applied Microbiology, University of Bari, 70126 Bari, Italy
J Agric Food Chem 53:4393-402. 2005....
Risk of gastrointestinal non-Hodgkin's lymphoma at diagnosis of celiac diseaseMarco Silano
J Gastroenterol Hepatol 20:657. 2005
