Marco Silano

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. doi request reprint Early tissue transglutaminase-mediated response underlies K562(S)-cell gliadin-dependent agglutination
    Marco Silano
    Unit of Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy
    Pediatr Res 71:532-8. 2012
  2. ncbi request reprint The new European legislation on traditional herbal medicines: main features and perspectives
    Marco Silano
    Department of Metabolism and Pathological Biochemistry, Istituto Superiore di Sanita, Rome, Italy
    Fitoterapia 75:107-16. 2004
  3. pmc Effect of the timing of gluten introduction on the development of celiac disease
    Marco Silano
    Unit of Human Nutrition and Health, Italian National Institute of Health, Viale Regina Elena 299, Rome, Italy
    World J Gastroenterol 16:1939-42. 2010
  4. ncbi request reprint Toxic, immunostimulatory and antagonist gluten peptides in celiac disease
    Marco Silano
    Department of Food Sciences, Human Nutrition and Health, Istituto Superiore di Sanita, Roma, Italy
    Curr Med Chem 16:1489-98. 2009
  5. doi request reprint The fifth anniversary of the European Food Safety Authority (EFSA): mission, organization, functioning and main results
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Roma, Italy
    Fitoterapia 79:149-60. 2008
  6. ncbi request reprint Effect of a gluten-free diet on the risk of enteropathy-associated T-cell lymphoma in celiac disease
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Dig Dis Sci 53:972-6. 2008
  7. ncbi request reprint Avenins from different cultivars of oats elicit response by coeliac peripheral lymphocytes
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy
    Scand J Gastroenterol 42:1302-5. 2007
  8. ncbi request reprint In vitro tests indicate that certain varieties of oats may be harmful to patients with coeliac disease
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Higher Institute of Health, Rome, Italy
    J Gastroenterol Hepatol 22:528-31. 2007
  9. pmc Delayed diagnosis of coeliac disease increases cancer risk
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, Italy
    BMC Gastroenterol 7:8. 2007
  10. ncbi request reprint Environmental factors of celiac disease: cytotoxicity of hulled wheat species Triticum monococcum, T. turgidum ssp. dicoccum and T. aestivum ssp. spelta
    Olimpia Vincentini
    Division of Food Science, Human Nutrition and Health, National Institute of Health, Rome, Italy
    J Gastroenterol Hepatol 22:1816-22. 2007

Collaborators

Detail Information

Publications27

  1. doi request reprint Early tissue transglutaminase-mediated response underlies K562(S)-cell gliadin-dependent agglutination
    Marco Silano
    Unit of Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy
    Pediatr Res 71:532-8. 2012
    ....
  2. ncbi request reprint The new European legislation on traditional herbal medicines: main features and perspectives
    Marco Silano
    Department of Metabolism and Pathological Biochemistry, Istituto Superiore di Sanita, Rome, Italy
    Fitoterapia 75:107-16. 2004
    ....
  3. pmc Effect of the timing of gluten introduction on the development of celiac disease
    Marco Silano
    Unit of Human Nutrition and Health, Italian National Institute of Health, Viale Regina Elena 299, Rome, Italy
    World J Gastroenterol 16:1939-42. 2010
    ..Here, we present and review the most recent evidences regarding the effect of timing of gluten introduction during weaning, the amount of gluten introduced and simultaneous breastfeeding, on the development of CD...
  4. ncbi request reprint Toxic, immunostimulatory and antagonist gluten peptides in celiac disease
    Marco Silano
    Department of Food Sciences, Human Nutrition and Health, Istituto Superiore di Sanita, Roma, Italy
    Curr Med Chem 16:1489-98. 2009
    ....
  5. doi request reprint The fifth anniversary of the European Food Safety Authority (EFSA): mission, organization, functioning and main results
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Roma, Italy
    Fitoterapia 79:149-60. 2008
    ....
  6. ncbi request reprint Effect of a gluten-free diet on the risk of enteropathy-associated T-cell lymphoma in celiac disease
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Dig Dis Sci 53:972-6. 2008
    ..8 P = 0.01). These results show that a strict gluten-free diet is protective towards the development of enteropathy-associated T-cell lymphoma...
  7. ncbi request reprint Avenins from different cultivars of oats elicit response by coeliac peripheral lymphocytes
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy
    Scand J Gastroenterol 42:1302-5. 2007
    ..The aim of this work was to evaluate whether avenins from different varieties of oats show different abilities in the activation of coeliac peripheral lymphocytes...
  8. ncbi request reprint In vitro tests indicate that certain varieties of oats may be harmful to patients with coeliac disease
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Higher Institute of Health, Rome, Italy
    J Gastroenterol Hepatol 22:528-31. 2007
    ..The presence of oats in gluten-free diet is controversial. The aim of this work is to evaluate if different varieties of oats exert different toxicity in coeliac disease...
  9. pmc Delayed diagnosis of coeliac disease increases cancer risk
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, Italy
    BMC Gastroenterol 7:8. 2007
    ..The aim of this paper is to estimate the risk of developing a neoplasm among non diagnosed coeliac patients and to evaluate if this risk correlates with the age of patients at diagnosis of coeliac disease...
  10. ncbi request reprint Environmental factors of celiac disease: cytotoxicity of hulled wheat species Triticum monococcum, T. turgidum ssp. dicoccum and T. aestivum ssp. spelta
    Olimpia Vincentini
    Division of Food Science, Human Nutrition and Health, National Institute of Health, Rome, Italy
    J Gastroenterol Hepatol 22:1816-22. 2007
    ..The purpose of this study was to investigate if species from ancient wheat could be considered as healthy food crops devoid or poor in cytotoxic prolamines for celiac disease...
  11. ncbi request reprint A 10-residue peptide from durum wheat promotes a shift from a Th1-type response toward a Th2-type response in celiac disease
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy
    Am J Clin Nutr 87:415-23. 2008
    ..Molecules able to shift the immune response from a Th1- to a Th2-type response have been suggested as therapeutic agents for Th1 autoimmune diseases...
  12. ncbi request reprint Potential new mechanisms of placental damage in celiac disease: anti-transglutaminase antibodies impair human endometrial angiogenesis
    Nicoletta Di Simone
    Department of Obstetrics and Gynecology, Policlinico A Gemelli, Universita Cattolica del Sacro Cuore, Rome, Italy
    Biol Reprod 89:88. 2013
    ..Our results identify pathogenic mechanisms of placental damage in CD. ..
  13. doi request reprint Two wheat decapeptides prevent gliadin-dependent maturation of human dendritic cells
    Luciana Giordani
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Viale Regina Elena, 299, 00161 Rome, Italy
    Exp Cell Res 321:248-54. 2014
    ..This finding could have implication for CD, raising the perspective of a potential therapeutic strategy alternative to a gluten free diet. ..
  14. pmc Exogenous HIV-1 Nef upsets the IFN-γ-induced impairment of human intestinal epithelial integrity
    Maria Giovanna Quaranta
    Department of Therapeutic Research and Medicine Evaluation, Istituto Superiore di Sanita, Roma, Italy
    PLoS ONE 6:e23442. 2011
    ..In the present study, we analyzed the effect of the accessory HIV-1 Nef protein on human epithelial cell line...
  15. ncbi request reprint Antagonist peptides of the gliadin T-cell stimulatory sequences: a therapeutic strategy for celiac disease
    Marco Silano
    Division of Food Sciences, Human Nutrition and Health, Istituto Superiore di Sanita, Viale Regina Elena, Roma, Italy
    J Clin Gastroenterol 42:S191-2. 2008
    ..These peptides have been obtained artificially by amino acids substitution of gliadin T-cell stimulatory sequences and an immunomodulatory sequence has been identified in the alcohol-soluble protein fraction of cultivars of durum wheat...
  16. doi request reprint T-cell response to different cultivars of farro wheat, Triticum turgidum ssp. dicoccum, in celiac disease patients
    Olimpia Vincentini
    Division of Food Safety and Veterinary Public Health, National Institute of Health, Viale Regina Elena 299, Rome, Italy
    Clin Nutr 28:272-7. 2009
    ..dicoccum) with contrasting storage protein compositions...
  17. ncbi request reprint A decapeptide from durum wheat prevents celiac peripheral blood lymphocytes from activation by gliadin peptides
    Marco Silano
    Division of Food Science, Human Nutrition and Health, Istituto Superiore di Sanita, Rome, Italy 00161
    Pediatr Res 61:67-71. 2007
    ..These data indicate that a peptide naturally occurring in durum wheat exerts in vitro an antagonist effect against gliadin toxicity and could have a protective effect in CD disease...
  18. doi request reprint Low-molecular-weight heparins induce decidual heparin-binding epidermal growth factor-like growth factor expression and promote survival of decidual cells undergoing apoptosis
    Nicoletta Di Simone
    Department of Obstetrics and Gynecology, Universita Cattolica del Sacro Cuore, Rome, Italy
    Fertil Steril 97:169-77.e1. 2012
    ..To evaluate the effects of low-molecular-weight heparins (LMWHs) on decidual heparin-binding epidermal growth factor-like growth factor (HB-EGF) expression/secretion and on TNF-α-induced decidual apoptosis...
  19. doi request reprint Docosahexaenoic acid modulates in vitro the inflammation of celiac disease in intestinal epithelial cells via the inhibition of cPLA2
    Olimpia Vincentini
    Unit of Human Nutrition and Health, Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanita, Viale Regina Elena, 299, 00161 Roma, Italy
    Clin Nutr 30:541-6. 2011
    ..The aims of the present work were to evaluate if: 1) intestinal epithelial cells have a role in the celiac inflammation, releasing AA, and 2) if DHA is able to modulate the celiac inflammation, down-regulating the release of AA...
  20. doi request reprint Role of magnified ileoscopy in the diagnosis of cases of coeliac disease with predominant abdominal symptoms
    Antonello Trecca
    Division of Operative Endoscopy and Gastroenterology, Fabio Di Giovambattista USI, Rome, Italy
    Scand J Gastroenterol 44:320-4. 2009
    ..This would be of clinical value in coeliac patients who show predominant abdominal symptoms and who undergo colonoscopy with ileoscopy as first clinical examination...
  21. doi request reprint Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage via apoptosis in vitro
    Nicoletta Di Simone
    Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy
    Am J Gastroenterol 105:2254-61. 2010
    ..The aim of this study was to determine whether anti-tissue transglutaminase (anti-tTG) antibodies are involved in the damage of trophoblastic cells in vitro...
  22. ncbi request reprint Clinical evolution of celiac disease in Italy 1982-2002
    Massimo D'Archivio
    Department of Metabolism and Pathological Biochemistry, Istituto Superiore di Sanita, Roma, Italy
    J Clin Gastroenterol 38:877-9. 2004
    ..The aim of this work is to assess how the clinical features of celiac disease have changed in Italy after the widespread introduction of serologic tests in 1993...
  23. ncbi request reprint VSL#3 probiotic preparation has the capacity to hydrolyze gliadin polypeptides responsible for Celiac Sprue
    Maria de Angelis
    Department of Plant Protection and Applied Microbiology, University of Bari, 70126 Bari, Italy
    Biochim Biophys Acta 1762:80-93. 2006
    ..Proteolytic activity by probiotic VSL#3 may have an importance during food processing to produce pre-digested and tolerated gliadins for increasing the palatability of gluten-free products...
  24. pmc Highly efficient gluten degradation by lactobacilli and fungal proteases during food processing: new perspectives for celiac disease
    Carlo G Rizzello
    Department of Plant Protection and Applied Microbiology, University of Bari, Bari, Italy
    Appl Environ Microbiol 73:4499-507. 2007
    ..Bread making was standardized to show the suitability of the detoxified wheat flour. Food processing by selected sourdough lactobacilli and fungal proteases may be considered an efficient approach to eliminate gluten toxicity...
  25. ncbi request reprint Risk of gastrointestinal non-Hodgkin's lymphoma at diagnosis of celiac disease
    Marco Silano
    J Gastroenterol Hepatol 20:657. 2005
  26. ncbi request reprint Pasta made from durum wheat semolina fermented with selected lactobacilli as a tool for a potential decrease of the gluten intolerance
    Raffaella di Cagno
    Department of Plant Protection and Applied Microbiology, University of Bari, 70126 Bari, Italy
    J Agric Food Chem 53:4393-402. 2005
    ....
  27. ncbi request reprint Prevention by a decapeptide from durum wheat of in vitro gliadin peptide-induced apoptosis in small-bowel mucosa from coeliac patients
    Marco Silano
    Scand J Gastroenterol 42:786-7. 2007