Research Topics
| D PerottiSummaryAffiliation: Istituto Nazionale Tumori Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Immunomodulation in a treatment program including pre- and post-operative interleukin-2 and chemotherapy for childhood osteosarcomaRoberto Luksch
Department of Medical Oncology, Pediatric Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
Tumori 89:263-8. 2003..An additional aim was to assess whether any correlation between the immune modifications and the clinical outcome could be found...- Bilateral preaxial polydactyly in a WAGR syndrome patientSiranoush Manoukian
Department of Experimental Oncology, Istituto Nazionale Tumori, Milan, Italy
Am J Med Genet A 134:426-9. 2005..These observations indicate that preaxial polydactyly may be another feature of the WAGR syndrome and suggest the existence of a related gene in the WAGR critical region or in its proximity... 
Genomic profiling by whole-genome single nucleotide polymorphism arrays in Wilms tumor and association with relapseDaniela Perotti
Department of Preventive and Predictive Medicine, Unit of Molecular Bases of Genetic Risk and Genetic Testing, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
Genes Chromosomes Cancer 51:644-53. 2012..Our study, besides confirming the role of 1q gains, identified a number of additional candidate genetic markers, warranting further molecular investigations...- Functional inactivation of the WTX gene is not a frequent event in Wilms' tumorsD Perotti
Department of Experimental Oncology and Laboratories, Genetic Susceptibility to Cancer Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
Oncogene 27:4625-32. 2008..Our findings indicate that previously reported estimates on the proportion of Wilms' tumors due to WTX alterations should be reconsidered... - Wilms tumor in monozygous twins: clinical, pathological, cytogenetic and molecular case reportDaniela Perotti
Department of Experimental Oncology and Laboratories, Istituto Nazionale Tumori, Milan, Italy
J Pediatr Hematol Oncol 27:521-5. 2005..To the authors' knowledge, this is the first report describing at both the clinical and genetic level a couple of monozygotic twins concordant for WT development... - WT1 gene analysis in sporadic early-onset and bilateral wilms tumor patients without associated abnormalitiesDaniela Perotti
Department of Experimental Oncology and Laboratories, Istituto Nazionale Tumori, 20133 Milan, Italy
J Pediatr Hematol Oncol 27:197-201. 2005..These results suggest that early age of diagnosis and bilaterality are not by themselves efficient predictors of germline WT1 alterations in WT patients without associated abnormalities... - Germline mutations of the POU6F2 gene in Wilms tumors with loss of heterozygosity on chromosome 7p14Daniela Perotti
Department of Experimental Oncology and Laboratories, Istituto Nazionale Tumori, Milan, Italy
Hum Mutat 24:400-7. 2004..Together with the finding of the expression of the POU6F2 mouse homolog in both fetal and adult kidney, our observations suggest that the gene is a tumor suppressor and is involved in hereditary predisposition to WT... - Molecular analysis of 1p32 genetic involvement in pediatric T-cell non-Hodgkin's lymphomaD Perotti
Division of Pediatric Oncology, Istituto Nazionale Tumori, Milan, Italy
Haematologica 84:110-3. 1999..The objective of this study was to assess the possibility of TAL1 involvement also in T-NHL... - Refinement within single yeast artificial chromosome clones of a minimal region commonly deleted on the short arm of chromosome 7 in Wilms tumoursD Perotti
Department of Experimental Oncology, Istituto Nazionale Tumori, Milano, Italy
Genes Chromosomes Cancer 31:42-7. 2001..For this reason, we speculate that the identified interval contains a gene whose inactivation is important for the development of at least a fraction of WTs... - Adult Wilms' tumor: A monoinstitutional experience and a review of the literatureMonica Terenziani
Unità di Oncologia Pediatrica, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
Cancer 101:289-93. 2004..The authors reviewed their institutional experience regarding adult patients with Wilms' tumor (WT) to assess their clinical characteristics and compliance with respect to children's treatment guidelines... - Treatment of high-risk relapsed Wilms tumor with dose-intensive chemotherapy, marrow-ablative chemotherapy, and autologous hematopoietic stem cell support: experience by the Italian Association of Pediatric Hematology and OncologyFilippo Spreafico
Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
Pediatr Blood Cancer 51:23-8. 2008..We evaluated an intensified chemotherapy strategy in children with Wilms tumor who relapsed with high-risk features... - Retrospective analysis of ploidy in primary osseous and extraosseous Ewing family tumors in childrenD Perotti
Division of Pediatric Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italy
Tumori 84:493-8. 1998..To retrospectively study the DNA content in a series of childhood Ewing Family Tumors (EFT), and to investigate its prognostic value... - Cytogenetic and molecular characterization of T-cell acute lymphoblastic leukemia as a second tumor after anaplastic large-cell lymphoma in a boyD Perotti
Division of Pediatric Oncology, Istituto Nazionale Tumori, Via G Venezian 1, 20133 Milan, Italy
Haematologica 84:554-7. 1999..The different T-cell receptor rearrangement evidenced in the two tumors indicates that this second malignancy most likely emerged de novo, but was plausibly related to the previous radiation and chemotherapy... - The murine Pou6f2 gene is temporally and spatially regulated during kidney embryogenesis and its human homolog is overexpressed in a subset of Wilms tumorsFrancesca Di Renzo
Department of Biology, University of Milan, Milan, Italy
J Pediatr Hematol Oncol 28:791-7. 2006.... - Non-chromosome 11-p syndromes in Wilms tumor patients: Clinical and cytogenetic report of two Down syndrome cases and one Turner syndrome caseFilippo Spreafico
Unit of Pediatric Oncology, Istituto Nazionale Tumori, Milano, Italy
Am J Med Genet A 143:85-8. 2007 - A novel WT1 mutation in a 46,XY boy with congenital bilateral cryptorchidism, nystagmus and Wilms tumorMonica Terenziani
Department of Medical Oncology, Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
Pediatr Nephrol 24:1413-7. 2009.... - Different mechanisms cause imprinting defects at the IGF2/H19 locus in Beckwith-Wiedemann syndrome and Wilms' tumourFlavia Cerrato
Dipartimento di Scienze Ambientali, Seconda Universita di Napoli, Via Vivaldi 43, 81100 Caserta, Italy
Hum Mol Genet 17:1427-35. 2008..Distinguishing between these two groups of cases is important for genetic counselling... - Molecular evidence of the independent origin of multiple Wilms tumors in a case of WAGR syndromeStefania Uccini
Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy
Pediatr Blood Cancer 51:344-8. 2008..This study investigated the genetic events leading to tumorigenesis in a patient affected with WAGR syndrome who developed multiple distinct Wilms tumors (WTs)...