Luca Pasina

Summary

Affiliation: Istituto di Ricerche Farmacologiche Mario Negri
Country: Italy

Publications

  1. pmc Critical appraisal of lurasidone in the management of schizophrenia
    Silvio Caccia
    Istituto di Ricerche Farmacologiche, Mario Negri, Milan, Italy
    Neuropsychiatr Dis Treat 8:155-68. 2012
  2. doi request reprint Medication non-adherence among elderly patients newly discharged and receiving polypharmacy
    L Pasina
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Drug Information Service for the Elderly, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156, Milan, Italy
    Drugs Aging 31:283-9. 2014
  3. doi request reprint Association of anticholinergic burden with cognitive and functional status in a cohort of hospitalized elderly: comparison of the anticholinergic cognitive burden scale and anticholinergic risk scale: results from the REPOSI study
    Luca Pasina
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Drug Information Service for the Elderly, Mario Negri Institute for Pharmacological Research, via Giuseppe La Masa, 19, 20156 Milan, Italy
    Drugs Aging 30:103-12. 2013
  4. doi request reprint Prevalence and appropriateness of drug prescriptions for peptic ulcer and gastro-esophageal reflux disease in a cohort of hospitalized elderly
    L Pasina
    Mario Negri Institute for Pharmacological Research, Milan, Italy
    Eur J Intern Med 22:205-10. 2011
  5. pmc A Population-based study of dementia in the oldest old: the Monzino 80-plus study
    Ugo Lucca
    Laboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    BMC Neurol 11:54. 2011
  6. doi request reprint Association between clusters of diseases and polypharmacy in hospitalized elderly patients: results from the REPOSI study
    Alessandro Nobili
    Mario Negri Institute for Pharmacological Research, Milano, Italy
    Eur J Intern Med 22:597-602. 2011
  7. doi request reprint Drug-drug interactions in a cohort of hospitalized elderly patients
    Luca Pasina
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Drug Information Service for the Elderly, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
    Pharmacoepidemiol Drug Saf 22:1054-60. 2013
  8. doi request reprint Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study
    Alessandro Nobili
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, via Giuseppe La Masa, 19, 20156 Milan, Italy
    Eur J Clin Pharmacol 67:507-19. 2011
  9. doi request reprint Changes in trend of antipsychotics prescription in patients treated with cholinesterase inhibitors after warnings from Italian Medicines Agency. Results from the EPIFARM-Elderly Project
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Eur Neuropsychopharmacol 22:569-77. 2012
  10. doi request reprint Antipsychotics prescription and cerebrovascular events in Italian older persons
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, IRCCS Istituto di Riceerche Farmacologiche Mario Negri, Milan, Italy
    J Clin Psychopharmacol 33:542-5. 2013

Detail Information

Publications19

  1. pmc Critical appraisal of lurasidone in the management of schizophrenia
    Silvio Caccia
    Istituto di Ricerche Farmacologiche, Mario Negri, Milan, Italy
    Neuropsychiatr Dis Treat 8:155-68. 2012
    ..Ongoing trials in patients with bipolar disorder are being completed but, again, efficacy and safety have been investigated only in a few short-term clinical trials...
  2. doi request reprint Medication non-adherence among elderly patients newly discharged and receiving polypharmacy
    L Pasina
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Drug Information Service for the Elderly, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156, Milan, Italy
    Drugs Aging 31:283-9. 2014
    ..Little is known about medication adherence among older adults living at home and requiring complex medication regimens...
  3. doi request reprint Association of anticholinergic burden with cognitive and functional status in a cohort of hospitalized elderly: comparison of the anticholinergic cognitive burden scale and anticholinergic risk scale: results from the REPOSI study
    Luca Pasina
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Drug Information Service for the Elderly, Mario Negri Institute for Pharmacological Research, via Giuseppe La Masa, 19, 20156 Milan, Italy
    Drugs Aging 30:103-12. 2013
    ..Drugs with anticholinergic effects are associated with adverse events such as delirium and falls as well as cognitive decline and loss of independence...
  4. doi request reprint Prevalence and appropriateness of drug prescriptions for peptic ulcer and gastro-esophageal reflux disease in a cohort of hospitalized elderly
    L Pasina
    Mario Negri Institute for Pharmacological Research, Milan, Italy
    Eur J Intern Med 22:205-10. 2011
    ..Inappropriate prescription is of particular concern among elderly patients, who have often multiple comorbidities and need many drugs...
  5. pmc A Population-based study of dementia in the oldest old: the Monzino 80-plus study
    Ugo Lucca
    Laboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    BMC Neurol 11:54. 2011
    ....
  6. doi request reprint Association between clusters of diseases and polypharmacy in hospitalized elderly patients: results from the REPOSI study
    Alessandro Nobili
    Mario Negri Institute for Pharmacological Research, Milano, Italy
    Eur J Intern Med 22:597-602. 2011
    ..We assessed which clusters of diseases are associated with polypharmacy in acute-care elderly in-patients...
  7. doi request reprint Drug-drug interactions in a cohort of hospitalized elderly patients
    Luca Pasina
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Drug Information Service for the Elderly, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
    Pharmacoepidemiol Drug Saf 22:1054-60. 2013
    ....
  8. doi request reprint Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study
    Alessandro Nobili
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, via Giuseppe La Masa, 19, 20156 Milan, Italy
    Eur J Clin Pharmacol 67:507-19. 2011
    ..We evaluated the prevalence and factors associated with polypharmacy and investigated the role of polypharmacy as a predictor of length of hospital stay and in-hospital mortality...
  9. doi request reprint Changes in trend of antipsychotics prescription in patients treated with cholinesterase inhibitors after warnings from Italian Medicines Agency. Results from the EPIFARM-Elderly Project
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Eur Neuropsychopharmacol 22:569-77. 2012
    ..Awaiting further studies to clarify their therapeutic role, physicians should prescribe antipsychotics very cautiously and only after careful risk-benefit assessment...
  10. doi request reprint Antipsychotics prescription and cerebrovascular events in Italian older persons
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, IRCCS Istituto di Riceerche Farmacologiche Mario Negri, Milan, Italy
    J Clin Psychopharmacol 33:542-5. 2013
    ..92). In conclusion, only typical antipsychotics were associated with an increased odd of CVEs, but the association was duration dependent. Persons prescribed simultaneously with AChEI and antipsychotics may be at a lower risk of CVEs. ..
  11. doi request reprint Cholinesterase inhibitor use in Alzheimer's disease: the EPIFARM-Elderly Project
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Pharmacoepidemiol Drug Saf 20:497-505. 2011
    ....
  12. doi request reprint Risk factors for hospital readmission of elderly patients
    Carlotta Franchi
    Mario Negri Institute for Pharmacological Research, Milan, Italy
    Eur J Intern Med 24:45-51. 2013
    ..The aim of this study was to identify which factors were associated with a risk of hospital readmission within 3 months after discharge of a sample of elderly patients admitted to internal medicine and geriatric wards...
  13. doi request reprint Geographical differences in the prevalence of chronic polypharmacy in older people: eleven years of the EPIFARM-Elderly Project
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, via Giuseppe La Masa, 19, 20156, Milan, Italy
    Eur J Clin Pharmacol 69:1477-83. 2013
    ..To compare the geographical differences in the prevalence of chronic polypharmacy in community-dwelling older people over 11 years...
  14. ncbi request reprint Use and misuse of antipsychotic drugs in patients with dementia in Alzheimer special care units
    Alessandro Nobili
    Laboratory of Quality Assessment of Geriatric Therapies and Services, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, Milan 20156, Italy
    Int Clin Psychopharmacol 24:97-104. 2009
    ..61-3.26). This study found high rate of use of antipsychotics in patients with dementia resident in Alzheimer special care units, frequent associations with other psychotropic medications and a strong correlation with BPSD...
  15. doi request reprint Changes in drug prescribing to Italian community-dwelling elderly people: the EPIFARM-Elderly Project 2000-2010
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, via Giuseppe La Masa, 19, 20156, Milan, Italy
    Eur J Clin Pharmacol 70:437-43. 2014
    ..To investigate the changes in the last decade (2000-2010) in drug prescribing among community-dwelling elderly people aged 65-94 years, in relation to age and sex...
  16. doi request reprint Drug utilization and polypharmacy in an Italian elderly population: the EPIFARM-elderly project
    Alessandro Nobili
    Laboratory of Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Pharmacoepidemiol Drug Saf 20:488-96. 2011
    ..To investigate the prescribing patterns and the prevalence of polypharmacy in community-dwelling elderly people, and to analyze the association of chronic medications and number of drug prescriptions with age and sex...
  17. doi request reprint How pre-marketing data can be used for predicting the weight of drug interactions in clinical practice
    Silvio Caccia
    Laboratory for Quality Assessment of Geriatric Therapies Services, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur J Intern Med 24:217-21. 2013
    ....
  18. doi request reprint Predicting the clinical relevance of drug interactions from pre-approval studies
    Silvio Caccia
    Laboratory of Drug Metabolism, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Drug Saf 32:1017-39. 2009
    ....
  19. pmc New atypical antipsychotics for schizophrenia: iloperidone
    Silvio Caccia
    Laboratory of Drug Metabolism, Mario Negri Institute for Pharmacological Research, 20156, Milan, Italy
    Drug Des Devel Ther 4:33-48. 2010
    ..Further comparative studies are needed to clarify the benefit/risk profile of iloperidone and its role in the treatment of schizophrenia...