Research Topics
| Alessandro NobiliSummaryAffiliation: Istituto di Ricerche Farmacologiche Mario Negri Country: Italy Publications
| Collaborators
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Detail Information
Publications
Low folate and the risk of cognitive and functional deficits in the very old: the Monzino 80-plus studyMauro Tettamanti
Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
J Am Coll Nutr 25:502-8. 2006....
Association of mild anemia with cognitive, functional, mood and quality of life outcomes in the elderly: the "Health and Anemia" studyUgo Lucca
Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
PLoS ONE 3:e1920. 2008..The objective of the present study was to cross-sectionally investigate the association of mild grade anemia with cognitive, functional, mood, and quality of life (QoL) variables in community-dwelling elderly persons...- The effect of a structured intervention on caregivers of patients with dementia and problem behaviors: a randomized controlled pilot studyAlessandro Nobili
Geriatric Neuropsychiatry Laboratory, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
Alzheimer Dis Assoc Disord 18:75-82. 2004..The number of families lost to follow-up, the relatively short duration of the study, and the ceiling effect due to the severity of the clinical characteristics of patients probably all partly dilute the observed findings... - Use and misuse of antipsychotic drugs in patients with dementia in Alzheimer special care unitsAlessandro Nobili
Laboratory of Quality Assessment of Geriatric Therapies and Services, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, Milan 20156, Italy
Int Clin Psychopharmacol 24:97-104. 2009..61-3.26). This study found high rate of use of antipsychotics in patients with dementia resident in Alzheimer special care units, frequent associations with other psychotropic medications and a strong correlation with BPSD... 
Drug utilization and polypharmacy in an Italian elderly population: the EPIFARM-elderly projectAlessandro Nobili
Laboratory of Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
Pharmacoepidemiol Drug Saf 20:488-96. 2011..To investigate the prescribing patterns and the prevalence of polypharmacy in community-dwelling elderly people, and to analyze the association of chronic medications and number of drug prescriptions with age and sex...- Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI studyAlessandro Nobili
Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, via Giuseppe La Masa, 19, 20156 Milan, Italy
Eur J Clin Pharmacol 67:507-19. 2011..We evaluated the prevalence and factors associated with polypharmacy and investigated the role of polypharmacy as a predictor of length of hospital stay and in-hospital mortality... - Potentially severe drug interactions in elderly outpatients: results of an observational study of an administrative prescription databaseA Nobili
Laboratory of Quality Assessment of Geriatric Therapies and Services, and Drug Information Services for the Elderly, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
J Clin Pharm Ther 34:377-86. 2009..To estimate the prevalence of potentially severe drug-drug interactions (DDIs) and their relationship with age, sex and number of prescribed drugs... - Alzheimer special care units compared with traditional nursing home for dementia care: are there differences at admission and in clinical outcomes?Alessandro Nobili
Laboratory of Quality Assessment of Geriatric Therapies and Services for the Elderly, Lombardy Region, Italy
Alzheimer Dis Assoc Disord 22:352-61. 2008..Studies comparing Alzheimer Special Care Units (ASCUs) with traditional nursing homes (NHs) have reported conflicting results... - Association between clusters of diseases and polypharmacy in hospitalized elderly patients: results from the REPOSI studyAlessandro Nobili
Mario Negri Institute for Pharmacological Research, Milano, Italy
Eur J Intern Med 22:597-602. 2011..We assessed which clusters of diseases are associated with polypharmacy in acute-care elderly in-patients... - Changes in trend of antipsychotics prescription in patients treated with cholinesterase inhibitors after warnings from Italian Medicines Agency. Results from the EPIFARM-Elderly ProjectCarlotta Franchi
Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
Eur Neuropsychopharmacol 22:569-77. 2012..Awaiting further studies to clarify their therapeutic role, physicians should prescribe antipsychotics very cautiously and only after careful risk-benefit assessment... - Association of mild anemia with hospitalization and mortality in the elderly: the Health and Anemia population-based studyEmma Riva
Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
Haematologica 94:22-8. 2009..The aim of the present population-based study was to prospectively investigate the association of mild grade anemia with hospitalization and mortality... - Prevalence, incidence and types of mild anemia in the elderly: the "Health and Anemia" population-based studyMauro Tettamanti
Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156 Milan, Italy
Haematologica 95:1849-56. 2010..The objectives of this study were to estimate the prevalence and incidence of mild grade anemia and to assess the frequency of anemia types in the elderly... - Cholinesterase inhibitor use in Alzheimer's disease: the EPIFARM-Elderly ProjectCarlotta Franchi
Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
Pharmacoepidemiol Drug Saf 20:497-505. 2011.... - Antidepressants utilization among elderly in Lombardy from 2000 to 2007: dispensing trends and appropriatenessAlberto Parabiaghi
Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
Eur J Clin Pharmacol 67:1077-83. 2011..To investigate the prevalence and incidence of antidepressant (AD) use in the elderly during an 8-year period and to evaluate AD treatment appropriateness... - Association of anticholinergic burden with cognitive and functional status in a cohort of hospitalized elderly: comparison of the anticholinergic cognitive burden scale and anticholinergic risk scale: results from the REPOSI studyLuca Pasina
Laboratory for Quality Assessment of Geriatric Therapies and Services, Drug Information Service for the Elderly, Mario Negri Institute for Pharmacological Research, via Giuseppe La Masa, 19, 20156 Milan, Italy
Drugs Aging 30:103-12. 2013..Drugs with anticholinergic effects are associated with adverse events such as delirium and falls as well as cognitive decline and loss of independence... - Risk factors for hospital readmission of elderly patientsCarlotta Franchi
Mario Negri Institute for Pharmacological Research, Milan, Italy
Eur J Intern Med 24:45-51. 2013..The aim of this study was to identify which factors were associated with a risk of hospital readmission within 3 months after discharge of a sample of elderly patients admitted to internal medicine and geriatric wards... - Trends in drug prescriptions to diabetic patients from 2000 to 2008 in Italy's Lombardy Region: a large population-based studyMarta Baviera
Laboratory of General Practice Research, Mario Negri Institute for Pharmacological Research, Via Giuseppe La Masa 19, 20156 Milan, Italy
Diabetes Res Clin Pract 93:123-30. 2011..To analyze the prescribing patterns of antidiabetic and cardiovascular medications among diabetics in the most highly populated Italian Region, from 2000 to 2008... - A Population-based study of dementia in the oldest old: the Monzino 80-plus studyUgo Lucca
Laboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
BMC Neurol 11:54. 2011.... - Predicting the clinical relevance of drug interactions from pre-approval studiesSilvio Caccia
Laboratory of Drug Metabolism, Mario Negri Institute for Pharmacological Research, Milan, Italy
Drug Saf 32:1017-39. 2009.... - How pre-marketing data can be used for predicting the weight of drug interactions in clinical practiceSilvio Caccia
Laboratory for Quality Assessment of Geriatric Therapies Services, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
Eur J Intern Med 24:217-21. 2013.... - Critical appraisal of lurasidone in the management of schizophreniaSilvio Caccia
Istituto di Ricerche Farmacologiche, Mario Negri, Milan, Italy
Neuropsychiatr Dis Treat 8:155-68. 2012..Ongoing trials in patients with bipolar disorder are being completed but, again, efficacy and safety have been investigated only in a few short-term clinical trials... - New atypical antipsychotics for schizophrenia: iloperidoneSilvio Caccia
Laboratory of Drug Metabolism, Mario Negri Institute for Pharmacological Research, 20156, Milan, Italy
Drug Des Devel Ther 4:33-48. 2010..Further comparative studies are needed to clarify the benefit/risk profile of iloperidone and its role in the treatment of schizophrenia... - A critical review of the full economic evaluations of pharmacological treatments for colorectal cancerLivio Garattini
CESAV, Centre for Health Economics, Mario Negri Institute for Pharmacological Research, 24020 Ranica BG, Italy
J Med Econ 11:177-97. 2008..This literature review makes a critical assessment of the methodology of the full economic evaluations (FEEs) conducted on colorectal cancer (CRC) pharmacological treatments... - Utilization and costs of antiepileptic drugs in the elderly: still an unsolved issueMassimiliano Beghi
Department of Clinical Psychiatry, University of Milano Bicocca, Milan, Italy
Drugs Aging 26:157-68. 2009..However, there are no cost-effectiveness studies in the elderly and further evidence is needed to confirm these assumptions...