Luisa Minghetti

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. pmc Regulation of Glial Cell Functions by PPAR-gamma Natural and Synthetic Agonists
    Antonietta Bernardo
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, 00161 Rome, Italy
    PPAR Res 2008:864140. 2008
  2. pmc PPAR-gamma, Microglial Cells, and Ocular Inflammation: New Venues for Potential Therapeutic Approaches
    Fiorella Malchiodi-Albedi
    Departmento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanita, 00161 Rome, Italy
    PPAR Res 2008:295784. 2008
  3. doi request reprint Early-life sex-dependent vulnerability to oxidative stress: the natural twining model
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    J Matern Fetal Neonatal Med 26:259-62. 2013
  4. ncbi request reprint Isoprostanes as biomarkers and mediators of oxidative injury in infant and adult central nervous system diseases
    Anita Greco
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Curr Neurovasc Res 1:341-54. 2004
  5. ncbi request reprint Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Italy
    Brain Res Brain Res Rev 48:251-6. 2005
  6. ncbi request reprint Role of inflammation in neurodegenerative diseases
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Curr Opin Neurol 18:315-21. 2005
  7. ncbi request reprint Multiple actions of the human immunodeficiency virus type-1 Tat protein on microglial cell functions
    Luisa Minghetti
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Neurochem Res 29:965-78. 2004
  8. doi request reprint Oxidative stress in twin neonates is influenced by birth weight and weight discordance
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Clin Biochem 44:654-8. 2011
  9. ncbi request reprint Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration
    Luisa Minghetti
    From the Departments of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Rome, Italy
    J Neuropathol Exp Neurol 66:363-71. 2007
  10. ncbi request reprint Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Neuropathol Exp Neurol 63:901-10. 2004

Collaborators

Detail Information

Publications56

  1. pmc Regulation of Glial Cell Functions by PPAR-gamma Natural and Synthetic Agonists
    Antonietta Bernardo
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, 00161 Rome, Italy
    PPAR Res 2008:864140. 2008
    ....
  2. pmc PPAR-gamma, Microglial Cells, and Ocular Inflammation: New Venues for Potential Therapeutic Approaches
    Fiorella Malchiodi-Albedi
    Departmento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanita, 00161 Rome, Italy
    PPAR Res 2008:295784. 2008
    ..The development of new in vivo and in vitro models to study ocular inflammation and how to modulate for the eye benefit will be instrumental for the search of effective therapies...
  3. doi request reprint Early-life sex-dependent vulnerability to oxidative stress: the natural twining model
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    J Matern Fetal Neonatal Med 26:259-62. 2013
    ..Thus, we aimed at evaluating oxidative stress in newborn twins by measuring oxidative stress biomarkers in cord blood...
  4. ncbi request reprint Isoprostanes as biomarkers and mediators of oxidative injury in infant and adult central nervous system diseases
    Anita Greco
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Curr Neurovasc Res 1:341-54. 2004
    ....
  5. ncbi request reprint Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Italy
    Brain Res Brain Res Rev 48:251-6. 2005
    ....
  6. ncbi request reprint Role of inflammation in neurodegenerative diseases
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Curr Opin Neurol 18:315-21. 2005
    ..This review addresses some of the most recent advances in our understanding of neuroinflammation...
  7. ncbi request reprint Multiple actions of the human immunodeficiency virus type-1 Tat protein on microglial cell functions
    Luisa Minghetti
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Neurochem Res 29:965-78. 2004
    ....
  8. doi request reprint Oxidative stress in twin neonates is influenced by birth weight and weight discordance
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Clin Biochem 44:654-8. 2011
    ..To evaluate the extent of oxidative stress in neonates born from multiple gestation pregnancies who are at high risk of prematurity and growth abnormalities...
  9. ncbi request reprint Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration
    Luisa Minghetti
    From the Departments of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Rome, Italy
    J Neuropathol Exp Neurol 66:363-71. 2007
    ....
  10. ncbi request reprint Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Neuropathol Exp Neurol 63:901-10. 2004
    ..Furthermore, the emerging role of COX-2 in behavioral and cognitive functions will be discussed...
  11. doi request reprint Pro-gliogenic effect of IL-1alpha in the differentiation of embryonic neural precursor cells in vitro
    Maria Antonietta Ajmone-Cat
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Rome, Italy
    J Neurochem 113:1060-72. 2010
    ....
  12. doi request reprint Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice
    Alessandra Berry
    Section of Behavioural Neurosciences, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Exp Gerontol 45:343-50. 2010
    ..Overall, the greater resilience to inflammation-induced changes in the p66(Shc-/-) mutants might underlie the better health status and the longevity characterizing these mice...
  13. doi request reprint Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves
    Chiara De Nuccio
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    J Neuropathol Exp Neurol 70:900-12. 2011
    ....
  14. doi request reprint Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells
    Maria Antonietta Ajmone-Cat
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    J Neurosci Res 90:575-87. 2012
    ....
  15. ncbi request reprint Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases
    Antonietta Bernardo
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Neurobiol Dis 22:25-32. 2006
    ..The dynamic regulation of the functional state of activated microglia by NCX 2216 helps explaining recent findings in Alzheimer's disease animal models and may offer new therapeutic opportunities for treating neurodegenerative diseases...
  16. ncbi request reprint Altered expression of cyclooxygenase-2, presenilins and oxygen radical scavenging enzymes in a rat model of global perinatal asphyxia
    Paola Piscopo
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161, Roma, Italy
    Exp Neurol 209:192-8. 2008
    ....
  17. doi request reprint Microglial polarization and plasticity: evidence from organotypic hippocampal slice cultures
    Maria Antonietta Ajmone-Cat
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, 00185 Rome, Italy
    Glia 61:1698-711. 2013
    ..Similar phenomena could occur in the intact brain and differently affect the vulnerability of mature and newborn neurons to noxious signals...
  18. doi request reprint Branched-chain amino acids influence the immune properties of microglial cells and their responsiveness to pro-inflammatory signals
    Roberta De Simone
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Biochim Biophys Acta 1832:650-9. 2013
    ..In addition to excitotoxicity, the altered immune profile of microglia might represent a further mechanism by which BCAAs might turn into toxicants and facilitate neurodegeneration...
  19. doi request reprint In vitro neuronal and glial differentiation from embryonic or adult neural precursor cells are differently affected by chronic or acute activation of microglia
    Emanuele Cacci
    Department of Cell and Developmental Biology, La Sapienza University, Piazzale Aldo Moro 5, 00185, Rome, Italy
    Glia 56:412-25. 2008
    ..Our data suggest that, in a chronically altered environment, persistently activated microglia can display protective functions that favor rather than hinder brain repair processes...
  20. doi request reprint Striatal 6-OHDA lesion in mice: Investigating early neurochemical changes underlying Parkinson's disease
    Igor Branchi
    Section of Behavioural Neurosciences, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, 00161 Rome, Italy
    Behav Brain Res 208:137-43. 2010
    ..Overall, the present findings suggest that a change of 5-HT metabolism and a modification of oxidative stress levels may play a role in the early PD degeneration phases...
  21. ncbi request reprint Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells
    Antonietta Bernardo
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    J Neuropathol Exp Neurol 68:797-808. 2009
    ..Thus, PPAR-gamma may promote recovery from demyelination by direct effects on oligodendrocytes...
  22. ncbi request reprint Differential lipid peroxidation, Mn superoxide, and bcl-2 expression contribute to the maturation-dependent vulnerability of oligodendrocytes to oxidative stress
    Antonietta Bernardo
    Neurobiology Section, Laboratory of Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    J Neuropathol Exp Neurol 62:509-19. 2003
    ....
  23. doi request reprint The stimulation of adenosine A2A receptors ameliorates the pathological phenotype of fibroblasts from Niemann-Pick type C patients
    Sergio Visentin
    Department of Cell Biology and Neuroscience, and Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Neurosci 33:15388-93. 2013
    ..Our findings strongly support the hypothesis that A2AR agonists may represent a therapeutic option for NPC1 and provide insights on their mechanisms of action. ..
  24. ncbi request reprint Cyclo-oxygenase-1 and -2 differently contribute to prostaglandin E2 synthesis and lipid peroxidation after in vivo activation of N-methyl-D-aspartate receptors in rat hippocampus
    Olimpia Pepicelli
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    J Neurochem 93:1561-7. 2005
    ..We suggest that both isoforms should be considered as possible therapeutic targets to prevent brain damage caused by excitotoxicity...
  25. ncbi request reprint Cognitive and neurological deficits induced by early and prolonged basal forebrain cholinergic hypofunction in rats
    Laura Ricceri
    Section of Behavioural Neurosciences, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, 00161 Rome, Italy
    Exp Neurol 189:162-72. 2004
    ....
  26. ncbi request reprint Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase
    Anita Greco
    Laboratory of Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    J Neurosci Res 71:844-52. 2003
    ....
  27. ncbi request reprint Adenosine A2A receptor antagonism and neuroprotection: mechanisms, lights, and shadows
    Patrizia Popoli
    Department of Drug Research and Evaluation, Istituto Superiore di Sanita, Roma, Italy
    Crit Rev Neurobiol 16:99-106. 2004
    ....
  28. ncbi request reprint Apoptotic PC12 cells exposing phosphatidylserine promote the production of anti-inflammatory and neuroprotective molecules by microglial cells
    Roberta De Simone
    Laboratory of Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    J Neuropathol Exp Neurol 62:208-16. 2003
    ....
  29. doi request reprint TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression
    Roberta De Simone
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    J Neurochem 115:450-9. 2010
    ..They also suggest that the modulation of microglial purinergic receptors expression by local factors, through direct and/or astrocyte-mediated actions, may represent a novel mechanism affecting neuroinflammatory response...
  30. ncbi request reprint 15-deoxy-delta12,14-prostaglandin J2 regulates the functional state and the survival of microglial cells through multiple molecular mechanisms
    Antonietta Bernardo
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Rome, Italy
    J Neurochem 87:742-51. 2003
    ....
  31. doi request reprint Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation, and differentiation
    Federica De Angelis
    Department of Biology and Biotechnologies Charles Darwin, Center of Neurobiology Research Daniel Bovet, La Sapienza University of Rome, Rome, Italy
    Dev Neurobiol 72:713-28. 2012
    ..This hypothesis is further supported by increased expression of Notch-1 in OL on muscarinic activation...
  32. ncbi request reprint Prostaglandin E2 and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: no impact on survival of seizure-generated neurons
    Maria Antonietta Ajmone-Cat
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Neurobiol Dis 23:23-35. 2006
    ..We propose that they modulate other aspects of synaptic and cellular plasticity, and thereby may influence epileptogenesis...
  33. pmc Transplacental exposure to AZT induces adverse neurochemical and behavioral effects in a mouse model: protection by L-acetylcarnitine
    Anna Rita Zuena
    Department of Physiology and Pharmacology Vittorio Erspamer, I Faculty of Medicine, Sapienza University of Rome, Rome, Italy
    PLoS ONE 8:e55753. 2013
    ....
  34. ncbi request reprint Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity
    Patrizia Popoli
    Department of Pharmacology, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Neurochem 89:1479-89. 2004
    ....
  35. ncbi request reprint Plasma levels of 15-F(2t)-isoprostane in newborn infants are affected by mode of delivery
    Anita Greco
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Clin Biochem 40:1420-2. 2007
    ..To investigate how the mode of delivery affects the level oxidative stress in newborns...
  36. ncbi request reprint Cerebrospinal fluid isoprostanes are not related to inflammatory activity in relapsing-remitting multiple sclerosis
    Anita Greco
    Department of Cell Biology and Neuroscience, Instituto Superiore di Sanita, Viale Regina Elena, 299, 00161, Rome, Italy
    J Neurol Sci 224:23-7. 2004
    ..We suggest that isoprostanes are not useful as surrogate inflammatory markers in MS. However, they may represent a sensitive index of degenerative phenomena, which can persist also in the absence of inflammatory activity...
  37. doi request reprint Prolonged lifespan with enhanced exploratory behavior in mice overexpressing the oxidized nucleoside triphosphatase hMTH1
    Gabriele De Luca
    Department of Environment and Primary Prevention, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Aging Cell 12:695-705. 2013
    ..Longevity conferred by overexpression of a single nucleotide hydrolase in hMTH1-Tg animals is an example of lifespan extension associated with healthy aging. It provides a link between aging and oxidative damage to nucleic acids. ..
  38. doi request reprint The matrix metalloproteinase inhibitor marimastat promotes neural progenitor cell differentiation into neurons by gelatinase-independent TIMP-2-dependent mechanisms
    Maddalena Sinno
    Department of Biology and Biotechnology Charles Darwin, Sapienza, University of Rome, Rome, Italy
    Stem Cells Dev 22:345-58. 2013
    ....
  39. ncbi request reprint Modulation of PGE(2) and TNFalpha by nitric oxide and LPS-activated RAW 264.7 cells
    Cecilia Guastadisegni
    Laboratory of Environmental Hygiene, Institito Superiore di Sanità, Rome, Italy
    Cytokine 19:175-80. 2002
    ....
  40. ncbi request reprint Non steroidal anti-inflammatory drugs and neurogenesis in the adult mammalian brain
    Maria Antonietta Ajmone-Cat
    Department of Cell Biology and Neurosciences, Section of Degenerative and Inflammatory Neurological Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299, 00161 Rome, Italy
    Curr Pharm Des 14:1435-42. 2008
    ..In the present article, we will review the current literature on the effects of NSAIDs on neurogenesis and briefly discuss the cellular or molecular mechanisms by which these drugs can modulate brain restorative processes...
  41. ncbi request reprint Nuclear receptor peroxisome proliferator-activated receptor-gamma is activated in rat microglial cells by the anti-inflammatory drug HCT1026, a derivative of flurbiprofen
    Antonietta Bernardo
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Rome, Italy
    J Neurochem 92:895-903. 2005
    ..The results suggest that HCT1026 may exert additional anti-inflammatory actions through PPAR-gamma activation, allowing a more effective control of microglial activation and brain inflammation...
  42. ncbi request reprint Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration
    Igor Branchi
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Rome, Italy
    J Neuropathol Exp Neurol 63:429-40. 2004
    ..Our findings support a role of DYRK1A overexpression in the neuronal abnormalities seen in Down syndrome and suggest that this pathology is linked to altered levels of proteins involved in the regulation of cell cycle...
  43. doi request reprint Isoprostanes in clinically isolated syndrome and early multiple sclerosis as biomarkers of tissue damage and predictors of clinical course
    Emilia Sbardella
    Department of Neurology and Psychiatry, Sapienza University, Rome, Italy
    Mult Scler 19:411-7. 2013
    ..Although axonal loss is present in MS patients since their first clinical symptoms, IsoP levels at this early stage have not been evaluated yet...
  44. ncbi request reprint Increased brain levels of F2-isoprostane are an early marker of behavioral sequels in a rat model of global perinatal asphyxia
    Gemma Calamandrei
    Section of Comparative Psychology, Laboratorio di Fisiopatologia, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161 Roma, Italy
    Pediatr Res 55:85-92. 2004
    ..The present 20-min asphyxia model might serve for the assessment of preventive and curative strategies to treat neurologic/behavioral disturbances associated with perinatal asphyxia...
  45. ncbi request reprint Atypical antiinflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction
    Roberta De Simone
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Italy
    Mol Neurobiol 29:197-212. 2004
    ....
  46. ncbi request reprint Increased levels of acute-phase inflammatory proteins in plasma of patients with sporadic CJD
    Federica Fratini
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Neurology 79:1012-8. 2012
    ..Screening plasma samples from patients with sporadic Creutzfeldt-Jakob disease (CJD) to discover diagnostic biomarkers...
  47. ncbi request reprint PPAR-gamma agonists as regulators of microglial activation and brain inflammation
    Antonietta Bernardo
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Curr Pharm Des 12:93-109. 2006
    ....
  48. ncbi request reprint Role of COX-2 in inflammatory and degenerative brain diseases
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Subcell Biochem 42:127-41. 2007
    ....
  49. pmc Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity
    Simona Capsoni
    European Brain Research Institute, Rome, Italy
    PLoS ONE 6:e17321. 2011
    ....
  50. ncbi request reprint Expression of phosphatidylserine receptor and down-regulation of pro-inflammatory molecule production by its natural ligand in rat microglial cultures
    Simone Roberta De
    Laboratory of Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    J Neuropathol Exp Neurol 61:237-44. 2002
    ..Our data suggest that, as for peripheral macrophages, PS through its receptor can modulate microglial activation toward an anti-inflammatory phenotype...
  51. ncbi request reprint Cyclooxygenase-2, prostaglandin E2, and microglial activation in prion diseases
    Luisa Minghetti
    Department of Cell Biology and Neurosciences, Degenerative and Inflammatory Neurological Diseases Unit, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Int Rev Neurobiol 82:265-75. 2007
    ....
  52. ncbi request reprint Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice
    Alessandra Berry
    Section of Behavioural Neurosciences, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, I 00161 Rome, Italy
    Exp Gerontol 42:37-45. 2007
    ..These data are discussed in relation to recent views, indicating new and complex interactions between oxidative stress and emotional stress...
  53. ncbi request reprint Minocycline in phenotypic models of Huntington's disease
    Kadiombo Bantubungi
    Laboratory of Neurophysiology, ULB Erasme, Brussels, Belgium
    Neurobiol Dis 18:206-17. 2005
    ..Altogether, these data suggested that, in HD, minocycline may counteract the development of caspase-dependent neurodegeneration, inflammation, but not calpain-dependent neuronal death...
  54. ncbi request reprint Cyclooxygenases and cyclooxygenase inhibitors in neurological and psychiatric diseases
    Luisa Minghetti
    Curr Pharm Des 14:1400. 2008