M Migliore

Summary

Affiliation: Istituto di Biofisica
Country: Italy

Publications

  1. ncbi Emerging rules for the distributions of active dendritic conductances
    Michele Migliore
    Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520-8001, USA
    Nat Rev Neurosci 3:362-70. 2002
  2. ncbi Signal propagation in oblique dendrites of CA1 pyramidal cells
    Michele Migliore
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT06520, USA
    J Neurophysiol 94:4145-55. 2005
  3. ncbi Electrophysiological properties and modeling of murine vomeronasal sensory neurons in acute slice preparations
    Ranken Shimazaki
    International School for Advanced Studies, SISSA, Sector of Neurobiology, Via Beirut 2-4, 34014 Trieste, Italy
    Chem Senses 31:425-35. 2006
  4. ncbi Dendritic action potentials connect distributed dendrodendritic microcircuits
    M Migliore
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT, USA
    J Comput Neurosci 24:207-21. 2008
  5. ncbi Distinct classes of pyramidal cells exhibit mutually exclusive firing patterns in hippocampal area CA3b
    Peter Hemond
    Department of Biology, The University of Texas at San Antonio, San Antonio, Texas 78249, USA
    Hippocampus 18:411-24. 2008
  6. ncbi Parallel network simulations with NEURON
    M Migliore
    Institute of Biophysics, National Research Council, via U La Malfa 153, 90146, Palermo, Italy
    J Comput Neurosci 21:119-29. 2006
  7. ncbi A modeling study suggesting a possible pharmacological target to mitigate the effects of ethanol on reward-related dopaminergic signaling
    Michele Migliore
    Insatritute of Biophysics, National Research Council, via U La Malfa 153, Palermo, Italy
    J Neurophysiol 99:2703-7. 2008
  8. ncbi A model for long-term potentiation and depression
    M Migliore
    Institute for Interdisciplinary Applications of Physics, National Research Council, Palermo, Italy
    J Comput Neurosci 2:335-43. 1995
  9. ncbi The role of distal dendritic gap junctions in synchronization of mitral cell axonal output
    M Migliore
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT, USA
    J Comput Neurosci 18:151-61. 2005
  10. ncbi Role of an A-type K+ conductance in the back-propagation of action potentials in the dendrites of hippocampal pyramidal neurons
    M Migliore
    National Research Council, Institute of Advanced Diagnostic Methodologies, Palermo, Italy
    J Comput Neurosci 7:5-15. 1999

Collaborators

Detail Information

Publications35

  1. ncbi Emerging rules for the distributions of active dendritic conductances
    Michele Migliore
    Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520-8001, USA
    Nat Rev Neurosci 3:362-70. 2002
    ....
  2. ncbi Signal propagation in oblique dendrites of CA1 pyramidal cells
    Michele Migliore
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT06520, USA
    J Neurophysiol 94:4145-55. 2005
    ..Thus the anatomical variability of CA1 pyramidal cells and their local distribution of voltage-gated channels may suit a powerful functional compartmentalization of the apical tree...
  3. ncbi Electrophysiological properties and modeling of murine vomeronasal sensory neurons in acute slice preparations
    Ranken Shimazaki
    International School for Advanced Studies, SISSA, Sector of Neurobiology, Via Beirut 2-4, 34014 Trieste, Italy
    Chem Senses 31:425-35. 2006
    ....
  4. ncbi Dendritic action potentials connect distributed dendrodendritic microcircuits
    M Migliore
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT, USA
    J Comput Neurosci 24:207-21. 2008
    ..Together they suggest a functional wiring of the olfactory bulb that could greatly expand the computational roles of the mitral-granule cell network...
  5. ncbi Distinct classes of pyramidal cells exhibit mutually exclusive firing patterns in hippocampal area CA3b
    Peter Hemond
    Department of Biology, The University of Texas at San Antonio, San Antonio, Texas 78249, USA
    Hippocampus 18:411-24. 2008
    ....
  6. ncbi Parallel network simulations with NEURON
    M Migliore
    Institute of Biophysics, National Research Council, via U La Malfa 153, 90146, Palermo, Italy
    J Comput Neurosci 21:119-29. 2006
    ..8 seconds and communication time of 1.3 seconds. The potential for speed-ups of several orders of magnitude makes practical the running of large network simulations that could otherwise not be explored...
  7. ncbi A modeling study suggesting a possible pharmacological target to mitigate the effects of ethanol on reward-related dopaminergic signaling
    Michele Migliore
    Insatritute of Biophysics, National Research Council, via U La Malfa 153, Palermo, Italy
    J Neurophysiol 99:2703-7. 2008
    ....
  8. ncbi A model for long-term potentiation and depression
    M Migliore
    Institute for Interdisciplinary Applications of Physics, National Research Council, Palermo, Italy
    J Comput Neurosci 2:335-43. 1995
    ..An interpretation of a number of experiments in terms of the molecular processes involved in LTP and LTD induction and maintenance, and the roles of a retrograde signal are presented and discussed...
  9. ncbi The role of distal dendritic gap junctions in synchronization of mitral cell axonal output
    M Migliore
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT, USA
    J Comput Neurosci 18:151-61. 2005
    ....
  10. ncbi Role of an A-type K+ conductance in the back-propagation of action potentials in the dendrites of hippocampal pyramidal neurons
    M Migliore
    National Research Council, Institute of Advanced Diagnostic Methodologies, Palermo, Italy
    J Comput Neurosci 7:5-15. 1999
    ..The simulations suggest that the time relationship between pre- and postsynaptic activity could help regulate the amplitude of back-propagating action potentials, especially in the distal portion of the dendritic tree...
  11. ncbi Modeling the attenuation and failure of action potentials in the dendrites of hippocampal neurons
    M Migliore
    National Research Council, Institute for Interdisciplinary Applications of Physics, Palermo, Italy
    Biophys J 71:2394-403. 1996
    ..The conditions under which branch point failures can be observed, and a few experimentally testable predictions, are presented and discussed...
  12. ncbi Long-term potentiation and depression induced by a stochastic conditioning of a model synapse
    M Migliore
    Institute of Advanced Diagnostic Methodologies, National Research Council, Palermo, Italy
    Biophys J 77:1234-43. 1999
    ....
  13. ncbi Computational model of the effects of stochastic conditioning on the induction of long-term potentiation and depression
    M Migliore
    Institute of Advanced Diagnostic Methodologies, National Research Council, Palermo, Italy
    Biol Cybern 81:291-8. 1999
    ....
  14. ncbi Quantitative modeling of perception and production of time intervals
    M Migliore
    Section of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520 8001, USA
    J Neurophysiol 86:2754-60. 2001
    ....
  15. ncbi Possible roles of retrograde messengers on LTP, LTD, and associative memory
    M Migliore
    Institute for Interdisciplinary Applications of Physics, National Research Council, Palermo, Italy
    Biosystems 40:127-32. 1997
    ..The model suggests that retrograde messengers could have a critical role in the induction and maintenance of associative LTP and LTD, by controlling the coupling between the two populations of synapses...
  16. ncbi A model of the effects of cognitive load on the subjective estimation and production of time intervals
    M Migliore
    Institute of Advanced Diagnostic Methodologies, National Research Council, CNR ISMEDA, Palermo, Italy
    Biosystems 58:187-93. 2000
    ..These effects are predicted to be independent of the number, location or specific implementations of the internal timing systems...
  17. ncbi Energy efficient modulation of dendritic processing functions
    M Migliore
    Institute for Interdisciplinary Applications of Physics, National Research Council, Palermo, Italy
    Biosystems 48:157-63. 1998
    ....
  18. ncbi Dendritic Ih selectively blocks temporal summation of unsynchronized distal inputs in CA1 pyramidal neurons
    M Migliore
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT, USA
    J Comput Neurosci 16:5-13. 2004
    ..The results allowed us to make the experimentally testable prediction that the Ih in these neurons is needed to reduce neuronal excitability selectively for distal unsynchronized, but not for synchronized, inputs...
  19. ncbi On the integration of subthreshold inputs from Perforant Path and Schaffer Collaterals in hippocampal CA1 pyramidal neurons
    Michele Migliore
    Section of Neurobiology, Yale University School of Medicine, New Haven, CT, USA
    J Comput Neurosci 14:185-92. 2003
    ....
  20. ncbi The olfactory granule cell: from classical enigma to central role in olfactory processing
    Gordon M Shepherd
    Department of Neurobiology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA
    Brain Res Rev 55:373-82. 2007
    ..Among other important properties, granule cells undergo neurogenesis from precursor cells throughout adult life. This originally enigmatic cell thus appears to play a critical role in olfactory processing...
  21. ncbi Single neuron binding properties and the magical number 7
    Michele Migliore
    Institute of Biophysics, National Research Council, Palermo, Italy
    Hippocampus 18:1122-30. 2008
    ..Our analysis predicts a straightforward physiological explanation for the observed puzzling limit of about 7 short-term memory items that can be stored by humans...
  22. ncbi Signaling properties of stratum oriens interneurons in the hippocampus of transgenic mice expressing EGFP in a subset of somatostatin-containing cells
    Federico Minneci
    Neuroscience Programme, International School for Advanced Studies, Trieste, Italy
    Hippocampus 17:538-53. 2007
    ....
  23. ncbi Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons
    Mala M Shah
    Department of Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
    Proc Natl Acad Sci U S A 105:7869-74. 2008
    ..These results indicate that axonal Kv7 channels, by controlling axonal RMP and action potential threshold, are fundamental for regulating the inherent firing properties of CA1 hippocampal neurons...
  24. ncbi Activity-dependent adjustments of the inhibitory network in the olfactory bulb following early postnatal deprivation
    Armen Saghatelyan
    Laboratory of Perception and Memory, Pasteur Institute, Centre National de la Recherche, Scientifique (URA 2182, 75015 Paris Cedex, France
    Neuron 46:103-16. 2005
    ..Together, this study reveals a unique form of adaptive response brought about exclusively by the cohort of newborn cells and used to maintain normal functioning of the MOB...
  25. ncbi On the initiation and propagation of dendritic spikes in CA1 pyramidal neurons
    Sonia Gasparini
    Neuroscience Center, Louisiana State University Health Science Center, New Orleans, Louisiana 70112, USA
    J Neurosci 24:11046-56. 2004
    ..Therefore, dendritic spikes function as efficient detectors of specific input patterns, ensuring that the neuronal response to high levels of input synchrony is a precisely timed action potential output...
  26. ncbi Dendritic K+ channels contribute to spike-timing dependent long-term potentiation in hippocampal pyramidal neurons
    Shigeo Watanabe
    Division of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 99:8366-71. 2002
    ..These results support the hypothesis that dendritic K(+) channels and the boosting of back-propagating action potentials contribute to the induction of LTP in CA1 neurons...
  27. ncbi Computational models of neuronal biophysics and the characterization of potential neuropharmacological targets
    Michele Ferrante
    Krasnow Institute for Advanced Study, George Mason University, 4400 University Drive, MS 2A1, Fairfax, Virginia 22030 4444, USA
    Curr Med Chem 15:2456-71. 2008
    ....
  28. ncbi Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites
    Nicholas P Poolos
    Division of Neuroscience, Department of Neurology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nat Neurosci 5:767-74. 2002
    ..These results demonstrate that neuronal excitability can be altered by drugs acting selectively on dendrites, and suggest an important role for I(h) in controlling dendritic excitability and epileptogenesis...
  29. ncbi Normalization of Ca2+ signals by small oblique dendrites of CA1 pyramidal neurons
    Andreas Frick
    Division of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 23:3243-50. 2003
    ..The higher density of I(K(A)) may have important implications for our understanding of synaptic integration and plasticity in these structures...
  30. ncbi Opinion: an integrated approach to classifying neuronal phenotypes
    Michele Migliore
    Yale University School of Medicine, Department of Neurobiology, P.O. Box 208001, New Haven, Connecticut 06520-8001, USA
    Nat Rev Neurosci 6:810-8. 2005
    ..This more comprehensive neuronal classification should be an improvement on traditional classifications for relating genotype to functional phenotype...
  31. ncbi A new bursting model of CA3 pyramidal cell physiology suggests multiple locations for spike initiation
    Maciej T Lazarewicz
    Krasnow Institute for Advanced Study, MS2A1 George Mason University, 4400 University Dr, Fairfax, VA 22030-4444, USA
    Biosystems 67:129-37. 2002
    ..In addition, these simulations demonstrate that models with considerably different distributions of active conductances can reproduce the same experimental bursting behavior with distinct biophysical mechanisms...
  32. ncbi Text mining neuroscience journal articles to populate neuroscience databases
    Chiquito J Crasto
    Center for Medical Informatics, Yale University, New Haven, CT, USA
    Neuroinformatics 1:215-37. 2003
    ..Software that uses the NeuroText approach can facilitate the creation of curated, special-interest, bibliography databases...
  33. ncbi SenseLab: new developments in disseminating neuroscience information
    Chiquito J Crasto
    Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Brief Bioinform 8:150-62. 2007
    ..We describe here: the new features for each database, the evolution of SenseLab's unifying database architecture and instances of SenseLab database interoperation with other neuroscience online resources...
  34. ncbi Semi-automated population of an online database of neuronal models (ModelDB) with citation information, using PubMed for validation
    Andrew P Davison
    Centre National de la Recherche Scientifique, 1 Avenue de la Terrasse (Bat. 33) 91198 Gif-sur-Yvette, France
    Neuroinformatics 2:327-32. 2004
    ..Our PERL scripts are available via a link in the web references section of this article...
  35. ncbi ModelDB: making models publicly accessible to support computational neuroscience
    Michele Migliore
    Neuroinformatics 1:135-9. 2003