Vincenzo Mazzaferro

Summary

Affiliation: Istituto Nazionale Tumori
Country: Italy

Publications

  1. ncbi request reprint Neuroendocrine tumors metastatic to the liver: how to select patients for liver transplantation?
    Vincenzo Mazzaferro
    Gastrointestinal Surgery and Liver Transplantation Unit, National Cancer Institute, Istituto Nazionale Tumori Fondazione IRCCS, Via Venezian 1, Milan 20133, Italy
    J Hepatol 47:460-6. 2007
  2. pmc Radiofrequency ablation of small hepatocellular carcinoma in cirrhotic patients awaiting liver transplantation: a prospective study
    Vincenzo Mazzaferro
    Gastrointestinal Surgery and Liver Transplantation, National Cancer Institute Istituto Nazionale Tumori, Milan, 20133 Italy
    Ann Surg 240:900-9. 2004
  3. ncbi request reprint Yttrium-90 radioembolization for intermediate-advanced hepatocellular carcinoma: a phase 2 study
    Vincenzo Mazzaferro
    Departments of Surgery, Liver Transplantation and Gastroenterology, Fondazione Istituto Nazionale Tumori IRCCS, National Cancer Institute, Milan, Italy
    Hepatology 57:1826-37. 2013
  4. pmc A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma
    Andreas A Schnitzbauer
    University Hospital Regensburg, Department of Surgery, Regensburg, Germany
    BMC Cancer 10:190. 2010
  5. ncbi request reprint Prevention of hepatocellular carcinoma recurrence with alpha-interferon after liver resection in HCV cirrhosis
    Vincenzo Mazzaferro
    Department of Surgery, Biomedical Statistics, Pathology, National Cancer Institute of Milan and Chair of Gastroenterology, Policlinico Foundation, Department of Medicine, University of Milan, Italy
    Hepatology 44:1543-54. 2006
  6. ncbi request reprint Nonhepatic glucose production in humans
    Alberto Battezzati
    International Center for the Assessment of Nutritional Status, DISTAM, University of Milan, 20133 Milan, Italy
    Am J Physiol Endocrinol Metab 286:E129-35. 2004
  7. doi request reprint The challenges of liver transplantation for hepatocellular carcinoma on cirrhosis
    Sherrie Bhoori
    Liver Unit and Hepato Oncology Group, National Cancer Institute, Fondazione Istituto Nazionale Tumori, Milan, Italy
    Transpl Int 23:712-22. 2010
  8. doi request reprint Comparative efficacy of sorafenib versus best supportive care in recurrent hepatocellular carcinoma after liver transplantation: a case-control study
    Carlo Sposito
    The Hepato Oncology Group, Gastro Intestinal Surgery, Liver Transplantation and Hepatology, Fondazione IRCCS Istituto Nazionale Tumori National Cancer Institute, Milan, Italy
    J Hepatol 59:59-66. 2013
  9. ncbi request reprint Heat shock proteins and their use as anticancer vaccines
    Giorgio Parmiani
    Istituto Nazionale Tumori, Milan, Italy
    Clin Cancer Res 10:8142-6. 2004
  10. ncbi request reprint Assessment of insulin sensitivity based on a fasting blood sample in men with liver cirrhosis before and after liver transplantation
    Gianluca Perseghin
    Nutrition Metabolism, Istituto Scientifico H San Raffaele, Milan, Italy
    Transplantation 76:697-702. 2003

Detail Information

Publications50

  1. ncbi request reprint Neuroendocrine tumors metastatic to the liver: how to select patients for liver transplantation?
    Vincenzo Mazzaferro
    Gastrointestinal Surgery and Liver Transplantation Unit, National Cancer Institute, Istituto Nazionale Tumori Fondazione IRCCS, Via Venezian 1, Milan 20133, Italy
    J Hepatol 47:460-6. 2007
  2. pmc Radiofrequency ablation of small hepatocellular carcinoma in cirrhotic patients awaiting liver transplantation: a prospective study
    Vincenzo Mazzaferro
    Gastrointestinal Surgery and Liver Transplantation, National Cancer Institute Istituto Nazionale Tumori, Milan, 20133 Italy
    Ann Surg 240:900-9. 2004
    ..Investigate possible predictors of response and assess efficacy and safety of RFA as a bridge to liver transplantation (OLT)...
  3. ncbi request reprint Yttrium-90 radioembolization for intermediate-advanced hepatocellular carcinoma: a phase 2 study
    Vincenzo Mazzaferro
    Departments of Surgery, Liver Transplantation and Gastroenterology, Fondazione Istituto Nazionale Tumori IRCCS, National Cancer Institute, Milan, Italy
    Hepatology 57:1826-37. 2013
    ..5% of patients, with no differences among stages. On multivariate analysis, tumor response was the sole variable affecting TTP (P < 0.001) and the second affecting survival (after Child-Pugh class)...
  4. pmc A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma
    Andreas A Schnitzbauer
    University Hospital Regensburg, Department of Surgery, Regensburg, Germany
    BMC Cancer 10:190. 2010
    ..Therefore, we designed a prospective RCT to determine if the mTOR inhibitor sirolimus can improve hepatocellular carcinoma (HCC)-free patient survival in liver transplant (LT) recipients with a pre-transplant diagnosis of HCC...
  5. ncbi request reprint Prevention of hepatocellular carcinoma recurrence with alpha-interferon after liver resection in HCV cirrhosis
    Vincenzo Mazzaferro
    Department of Surgery, Biomedical Statistics, Pathology, National Cancer Institute of Milan and Chair of Gastroenterology, Policlinico Foundation, Department of Medicine, University of Milan, Italy
    Hepatology 44:1543-54. 2006
    ..3; 95% CI: 0.09-0.9; P = .04). In conclusion, IFN does not affect overall prevention of HCC recurrence after resection, but it may reduce late recurrence in HCV-pure patients receiving effective treatment...
  6. ncbi request reprint Nonhepatic glucose production in humans
    Alberto Battezzati
    International Center for the Assessment of Nutritional Status, DISTAM, University of Milan, 20133 Milan, Italy
    Am J Physiol Endocrinol Metab 286:E129-35. 2004
    ..The kidney is the main, but possibly not the unique, source of extrahepatic glucose production...
  7. doi request reprint The challenges of liver transplantation for hepatocellular carcinoma on cirrhosis
    Sherrie Bhoori
    Liver Unit and Hepato Oncology Group, National Cancer Institute, Fondazione Istituto Nazionale Tumori, Milan, Italy
    Transpl Int 23:712-22. 2010
    ..Accepting this challenge has been part of the history of LT and will endure so also for the future...
  8. doi request reprint Comparative efficacy of sorafenib versus best supportive care in recurrent hepatocellular carcinoma after liver transplantation: a case-control study
    Carlo Sposito
    The Hepato Oncology Group, Gastro Intestinal Surgery, Liver Transplantation and Hepatology, Fondazione IRCCS Istituto Nazionale Tumori National Cancer Institute, Milan, Italy
    J Hepatol 59:59-66. 2013
    ..The aim of this study was to evaluate the efficacy of sorafenib, compared to best supportive care (BSC), in two cohorts of patients which presented with hepatocellular carcinoma (HCC) recurrence after LT...
  9. ncbi request reprint Heat shock proteins and their use as anticancer vaccines
    Giorgio Parmiani
    Istituto Nazionale Tumori, Milan, Italy
    Clin Cancer Res 10:8142-6. 2004
  10. ncbi request reprint Assessment of insulin sensitivity based on a fasting blood sample in men with liver cirrhosis before and after liver transplantation
    Gianluca Perseghin
    Nutrition Metabolism, Istituto Scientifico H San Raffaele, Milan, Italy
    Transplantation 76:697-702. 2003
    ..This study aimed to test whether these simple indices are reliable measures of insulin sensitivity in patients with liver cirrhosis before and after liver transplantation (LTx)...
  11. ncbi request reprint CT cholangiography: assessment of feasibility and diagnostic reliability
    Carlo Morosi
    Department of Radiology, National Cancer Institute, Via Venezian 1, Milan 20100, Italy
    Eur J Radiol 72:114-7. 2009
    ..To assess the reliability of computed tomography (CT) cholangiography in evaluating the anatomy of the intrahepatic biliary ducts...
  12. ncbi request reprint Natural killer and NK-Like T-cell activation in colorectal carcinoma patients treated with autologous tumor-derived heat shock protein 96
    Lorenzo Pilla
    Unit of Immunotherapy of Human Tumors, Istituto Nazionale Tumori, Milan, Italy
    Cancer Res 65:3942-9. 2005
    ..Altogether, these findings identify the activation of the NK compartment as an additional immunologic effect of autologous tumor-derived HSP96 administration in cancer patients...
  13. doi request reprint Personalized molecular targeted therapy in advanced, recurrent hepatocellular carcinoma after liver transplantation: a proof of principle
    Sherrie Bhoori
    Liver Unit, Hepato Oncology Group and Molecular Pathology, National Cancer Institute, Fondazione Istituto Nazionale Tumori, Milan, Italy
    J Hepatol 52:771-5. 2010
    ..For several aberrantly activated pathways in hepatocarcinoma, surrogate markers of activation can be assessed by immunohistochemistry, although associations with in vivo response to targeted therapies are still lacking...
  14. doi request reprint Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis
    Vincenzo Mazzaferro
    National Cancer Institute, Milan, Italy
    Lancet Oncol 10:35-43. 2009
    ....
  15. ncbi request reprint Resting energy expenditure in diabetic and nondiabetic patients with liver cirrhosis: relation with insulin sensitivity and effect of liver transplantation and immunosuppressive therapy
    Gianluca Perseghin
    Division of Internal Medicine, Istituto H San Raffaele, Milan, Italy
    Am J Clin Nutr 76:541-8. 2002
    ..Hypermetabolism, insulin resistance, and diabetes are common in patients with liver cirrhosis...
  16. ncbi request reprint Heat shock proteins: biological functions and clinical application as personalized vaccines for human cancer
    Chiara Castelli
    Unit of Immunotherapy of Human Tumors, Istituto Nazionale per lo Studio e la Cura dei Tumori, Via G Venezian 1, 20133, Milan, Italy
    Cancer Immunol Immunother 53:227-33. 2004
    ..The immunological properties of these proteins and their implications for vaccine in human cancer will be discussed. Immunological and clinical data of phase I/II studies in melanoma and colorectal cancer patients will be reviewed...
  17. doi request reprint Transhepatic anterior approach to the inferior vena cava in large retroperitoneal tumors resected en bloc with the right liver lobe
    Jorgelina Coppa
    Hepato Pancreato Biliary Surgery and Liver Transplantation Unit, Istituto Nazionale Tumori National Cancer Institute IRCCS Foundation, Milan, Italy
    Surgery 154:1061-8. 2013
    ..The anterior approach to the IVC associated with the hanging maneuver for liver transection, originally described in large hepatic tumors, may also facilitate removal of large masses set behind the liver...
  18. pmc Liver transplantation for hepatocellular carcinoma
    Vincenzo Mazzaferro
    Department of Surgery, National Cancer Institute, Milan, Italy
    Ann Surg Oncol 15:1001-7. 2008
    ....
  19. pmc Evidence of distinct tumour-propagating cell populations with different properties in primary human hepatocellular carcinoma
    Federico Colombo
    Experimental Hepatology Laboratory, Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    PLoS ONE 6:e21369. 2011
    ..The aim of this study was to investigate and characterise tumour-propagating cell (TPC) compartments within human hepatocellular carcinoma (HCC)...
  20. ncbi request reprint Results of liver transplantation: with or without Milan criteria?
    Vincenzo Mazzaferro
    Gastrointestinal Surgery and Liver Transplantation Unit, National Cancer Institute, Milan, Italy
    Liver Transpl 13:S44-7. 2007
  21. ncbi request reprint Amino acid kinetics during the anhepatic phase of liver transplantation
    Alberto Battezzati
    Universita degli Studi di Milano, Milan, Italy
    Diabetes 51:1690-8. 2002
    ..The initial events after liver removal are an accumulation of three-carbon compounds, an acceleration of alanine turnover, and limited nitrogen storage in alanine and glutamine...
  22. ncbi request reprint Fibroblastic reticular cell tumor of the spleen: report of a case and review of the entity
    Maritza Martel
    Department of Pathology, Hepato Pancreato Biliary Unit, National Cancer Institute, Milan, Italy
    Hum Pathol 34:954-7. 2003
    ..To the best of our knowledge, this is the first report of malignant FBRC tumor arising in the spleen. The differential diagnosis of splenic tumors with inflammatory pseudotumor-like features is discussed...
  23. ncbi request reprint Solid-pseudopapillary tumor of the pancreas (Frantz tumor) in children
    Michela Casanova
    Pediatric Oncology Unit, Istituto Nazionale Tumori, Via G Venezian, Milano, Italy
    Med Pediatr Oncol 41:74-6. 2003
  24. ncbi request reprint Etoposide, cisplatin, epirubicin chemotherapy in the treatment of pediatric liver tumors
    Michela Casanova
    Pediatric Oncology Unit, Istituto Nazionale Tumori, Via Venezian, 1 20133 Milano, Italy
    Pediatr Hematol Oncol 22:189-98. 2005
    ..EPE chemotherapy seems to be effective in the treatment of childhood malignant liver tumors. Etoposide could be suggested as part of intensive multidrug regimens for HCC and high-risk HB...
  25. ncbi request reprint Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer
    Vincenzo Mazzaferro
    Units of Hepatobiliary and Gastro Pancreatic Surgery, Istituto Nazionale per lo Studio e la Cura Tumori, 20133 Milan, Italy
    Clin Cancer Res 9:3235-45. 2003
    ..We tested in humans whether vaccination with HSPPC-gp96 (Oncophage) from autologous liver metastases of colorectal carcinoma induces cancer-specific T-cell responses in patients rendered disease free by surgery...
  26. ncbi request reprint Prognostic role of pancreatic metastases from renal cell carcinoma: results from an Italian center
    Paolo Grassi
    Medical Oncology Unit 1, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
    Clin Genitourin Cancer 11:484-8. 2013
    ..The prognostic value of pancreatic metastases in the era of TTs is unclear. We evaluated outcomes in a cohort of mRCC patients with pancreatic metastases (PmRCC) who were treated with TTs...
  27. ncbi request reprint Percutaneous transhepatic biliary drainage in the management of postsurgical biliary leaks in patients with nondilated intrahepatic bile ducts
    Guido Cozzi
    Department of Radiology, Radiologia 3 Unit, National Cancer Institute Istituto Nazionale Tumori, Milan, Italy
    Cardiovasc Intervent Radiol 29:380-8. 2006
    ....
  28. ncbi request reprint Thyroid as a target of metastases. A case of foregut neuroendocrine carcinoma with multiple abdominal metastases and a thyroid localization after 21 years
    Franco Mattavelli
    Otorhinolaryngology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
    Tumori 94:110-3. 2008
    ..e., a medullary thyroid carcinoma. This case report is peculiar because of the multiple sites of abdominal relapses, the long time interval between relapses (21 years), and the positive outcome after surgical treatment...
  29. pmc Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes
    Daniela Sia
    Barcelona Clínic Liver Cancer Group HCC Translational Research Laboratory, Liver Unit, Pathology Department, Institut d Investigacions Biomediques August Pi i Sunyer, Liver Unit, Hospital Clinic, Universitat de Barcelona, Barcelona, Catalonia, Spain
    Gastroenterology 144:829-40. 2013
    ..We performed an integrative genomic analysis of ICC samples from a large series of patients...
  30. ncbi request reprint Candidates for liver transplantation for cancer: physical, psychological, and social conditions
    Laura Gangeri
    Psychology and Liver Surgery and Transplantation Units, National Cancer Institute, 20133 Milan, Italy
    Transplantation 73:1627-35. 2002
    ..There is little knowledge of the psychological and social conditions of candidates for liver transplantation and the meaning that these patients attribute to those conditions...
  31. doi request reprint Importance of early nutritional screening in patients with gastric cancer
    Cecilia Gavazzi
    Clinical Nutrition Unit, National Cancer Institute, Via Venezian 1, 20133 Milan, Italy
    Br J Nutr 106:1773-8. 2011
    ..Moreover, NRS is directly correlated with tumour stage and inversely correlated with QoL, which makes it a useful tool to identify patients in need of an early nutritional intervention during oncological treatments...
  32. pmc Gene-expression signature of vascular invasion in hepatocellular carcinoma
    Beatriz Minguez
    Mount Sinai Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Surgical Oncology, Department of Surgery, Department of Pathology, Department of Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Hepatol 55:1325-31. 2011
    ..While macroscopic vascular invasion can be detected by radiological techniques, pre-operative detection of microscopic vascular invasion, which complicates 30-40% of patients with early tumors, remains elusive...
  33. doi request reprint Simultaneous characterization of progenitor cell compartments in adult human liver
    Laura Porretti
    Center of Transfusion Medicine, Cellular Therapy and Cryobiology, IRCCS Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Cytometry A 77:31-40. 2010
    ..We also optimized a flow cytometry approach that will be useful in exploring the contribution of these cells to the pathogenesis of liver disease...
  34. ncbi request reprint Feasibility of peritonectomy associated with intraperitoneal hyperthermic perfusion in patients with Pseudomyxoma peritonei
    Marcello Deraco
    Department of Surgery, Melanoma and Sarcoma Unit, National Cancer Institute of Milan, Italy
    Tumori 88:370-5. 2002
    ....
  35. pmc Failure of Intravenous Silibinin Monotherapy to Prevent Hepatitis C Genotype 2A Liver Graft Reinfection
    Alessio Aghemo
    Angela Maria e Antonio Migliavacca Center for Liver Disease, First Division of Gastroenterology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
    Hepat Mon 12:411-4. 2012
    ..Based on these findings, we decided to offer such a therapy to a 65 year old woman on the oLT list...
  36. ncbi request reprint Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of melanoma- and colon carcinoma-specific T cells
    Licia Rivoltini
    Unit of Immunotherapy of Human Tumor, Gastrointestinal and Liver Surgery Unit, and Colorectal Surgery Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
    J Immunol 171:3467-74. 2003
    ....
  37. ncbi request reprint Helicobacter species sequences in liver samples from patients with and without hepatocellular carcinoma
    Rinaldo Pellicano
    Ambulatorio di Gastroenterologia, Ospedale S Giovanni Battista, Via Chiabrera 34, III piano, 10126 Torino, Italy
    World J Gastroenterol 10:598-601. 2004
    ..We investigated whether Helicobacter spp. sequences could be detected in the liver of patients with cirrhosis and HCC compared to subjects with metastasis to liver from colon cancer...
  38. pmc Focal gains of VEGFA and molecular classification of hepatocellular carcinoma
    Derek Y Chiang
    Department of Medical Oncology and Center for Cancer Genome Discovery, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Cancer Res 68:6779-88. 2008
    ..Furthermore, the prevalence of VEGFA high-level gains in multiple tumor types suggests indications for clinical trials of antiangiogenic therapies...
  39. ncbi request reprint Living donor liver transplantation for hepatocellular carcinoma exceeding conventional criteria: questions, answers and demands for a common language
    Pietro Majno
    Liver Transpl 12:896-8. 2006
  40. ncbi request reprint A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis
    Josep M Llovet
    Mount Sinai Liver Cancer Program, Department of Medicine, Mount Sinai School of Medicine, New York 10029, USA
    Gastroenterology 131:1758-67. 2006
    ..Small liver nodules approximately 2 cm are difficult to characterize by radiologic or pathologic examination. Our aim was to identify a molecular signature to diagnose early hepatocellular carcinoma (HCC)...
  41. pmc Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation
    Sigal Kremer-Tal
    Division of Liver Diseases and Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA
    J Hepatol 46:645-54. 2007
    ..Hepatocellular carcinoma (HCC) has the most rapidly rising cancer incidence in the US and Europe. The KLF6 tumor suppressor is frequently inactivated in HCC by loss-of-heterozygosity (LOH) and/or mutation...
  42. ncbi request reprint Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma
    Elisa Wurmbach
    Mount Sinai Liver Cancer Program, Division of Hematology Oncology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Hepatology 45:938-47. 2007
    ....
  43. ncbi request reprint Resection, transplantation, either, or both? Other pieces of the puzzle
    Pietro Majno
    Liver Transpl 11:1177-80. 2005
  44. ncbi request reprint Split and whole liver transplantation outcomes: a comparative cohort study
    Massimo Cardillo
    Transplant Immunology and Blood Bank, Maggiore Policlinico Hospital, Milano, Italy
    Liver Transpl 12:402-10. 2006
    ..2 to 16.2% was observed. Such results justify a more widespread adoption of SLT protocols, organizational difficulties not being a limit for the application of such technique...
  45. ncbi request reprint Resection and liver transplantation for hepatocellular carcinoma
    Josep M Llovet
    BCLC Group, Liver Unit, Digestive Disease Institute, IDIBAPS, Hospital Clinic, University of Barcelona, Catalonia, Spain
    Semin Liver Dis 25:181-200. 2005
    ..Living donor liver transplantation is having a minor impact in HCC management. Molecular markers are needed to better select the candidates for surgery...
  46. ncbi request reprint Prophylaxis of hepatitis B virus recurrence after liver transplantation in carriers of lamivudine-resistant mutants
    Alfredo Marzano
    Department of Gastroenterology, San Giovanni Battista Hospital, Turin, Italy
    Liver Transpl 11:532-8. 2005
    ....
  47. doi request reprint Sorafenib in advanced hepatocellular carcinoma
    Josep M Llovet
    Barcelona Clinic Liver Cancer Group, Institut d Investigacions Biomediques August Pi i Sunyer, Centro de Investigaciones en Red de Enfermedades Hepáticas y Digestivas Hospital Clínic Barcelona, Barcelona
    N Engl J Med 359:378-90. 2008
    ..A preliminary study suggested that sorafenib, an oral multikinase inhibitor of the vascular endothelial growth factor receptor, the platelet-derived growth factor receptor, and Raf may be effective in hepatocellular carcinoma...
  48. ncbi request reprint The place of liver transplantation in the treatment of hepatic epitheloid hemangioendothelioma: report of the European liver transplant registry
    Jan P Lerut
    Abdominal Transplant Unit, University Hospitals St Luc, Brussels, Belgium
    Ann Surg 246:949-57; discussion 957. 2007
    ..Hepatic epitheloid hemangioendothelioma (HEHE) is a rare low-grade vascular tumor. Its treatment algorithm is still unclear mainly due to a lack of larger clinical experiences with detailed long-term follow-up...
  49. ncbi request reprint Chromosome instability in human hepatocellular carcinoma depends on p53 status and aflatoxin exposure
    Pascal Pineau
    Unité d Organisation Nucléaire et Oncogénèse, INSERM U579, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mutat Res 653:6-13. 2008
    ..4% vs. 16.7%, p<0.0001). We suggest that AFB1-associated mutagenesis represents a plausible cause for the higher chromosome instability observed in Chinese HCCs, when compared with European primary liver carcinomas...
  50. ncbi request reprint Transthyretin RNA profiling in livers from transplanted patients affected by familial amyloidotic polyneuropathy, and identification of a dual transcription start point
    Paola Rimessi
    Dipartimento di Medicina Sperimentale e Diagnostica, Sezione di Genetica Medica, University of Ferrara, Ferrara, Italy
    Liver Int 26:211-20. 2006
    ..RNA analysis revealed that this region is represented in all foetal/adult tissues analysed. We discussed the implications of this finding which might provide perspectives for better understanding the TTR gene expression...