Serge Masson

Summary

Affiliation: Istituto di Ricerche Farmacologiche Mario Negri
Country: Italy

Publications

  1. ncbi request reprint Cardiovascular oxidative stress is reduced by an ACE inhibitor in a rat model of streptozotocin-induced diabetes
    Fabio Fiordaliso
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milan, Italy
    Life Sci 79:121-9. 2006
  2. pmc Anaesthesiological strategies in elective craniotomy: randomized, equivalence, open trial--the NeuroMorfeo trial
    Giuseppe Citerio
    Neuroanaesthesia and Neurointensive Care Unit, Department of Perioperative Medicine and Intensive Care, San Gerardo Hospital, Monza, Milano, Italy
    Trials 10:19. 2009
  3. ncbi request reprint Direct comparison of B-type natriuretic peptide (BNP) and amino-terminal proBNP in a large population of patients with chronic and symptomatic heart failure: the Valsartan Heart Failure (Val-HeFT) data
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Clin Chem 52:1528-38. 2006
  4. doi request reprint Prognostic value of changes in N-terminal pro-brain natriuretic peptide in Val-HeFT (Valsartan Heart Failure Trial)
    Serge Masson
    Department of Cardiovascular Reearch, Istituto Mario Negri, Milan, Italy
    J Am Coll Cardiol 52:997-1003. 2008
  5. ncbi request reprint Clinical, neurohormonal, and inflammatory markers and overall prognostic role of chronic obstructive pulmonary disease in patients with heart failure: data from the Val-HeFT heart failure trial
    Lidia Staszewsky
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    J Card Fail 13:797-804. 2007
  6. ncbi request reprint Incremental prognostic value of changes in B-type natriuretic peptide in heart failure
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Am J Med 119:70.e23-30. 2006
  7. ncbi request reprint Effect of beta-adrenergic and renin-angiotensin system blockade on myocyte apoptosis and oxidative stress in diabetic hypertensive rats
    Fabio Fiordaliso
    Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research, 20157 Milan, Italy
    Life Sci 81:951-9. 2007
  8. ncbi request reprint The prognostic value of big endothelin-1 in more than 2,300 patients with heart failure enrolled in the Valsartan Heart Failure Trial (Val-HeFT)
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    J Card Fail 12:375-80. 2006
  9. ncbi request reprint The comparative prognostic value of plasma neurohormones at baseline in patients with heart failure enrolled in Val-HeFT
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur Heart J 25:292-9. 2004
  10. doi request reprint The predictive value of stable precursor fragments of vasoactive peptides in patients with chronic heart failure: data from the GISSI-heart failure (GISSI-HF) trial
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, Milan, Italy
    Eur J Heart Fail 12:338-47. 2010

Collaborators

Detail Information

Publications51

  1. ncbi request reprint Cardiovascular oxidative stress is reduced by an ACE inhibitor in a rat model of streptozotocin-induced diabetes
    Fabio Fiordaliso
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milan, Italy
    Life Sci 79:121-9. 2006
    ..The absence of an additive effect, suggests a common mechanism of action, through the reduction of oxidative stress...
  2. pmc Anaesthesiological strategies in elective craniotomy: randomized, equivalence, open trial--the NeuroMorfeo trial
    Giuseppe Citerio
    Neuroanaesthesia and Neurointensive Care Unit, Department of Perioperative Medicine and Intensive Care, San Gerardo Hospital, Monza, Milano, Italy
    Trials 10:19. 2009
    ..This trial, named NeuroMorfeo, aims to assess the equivalence between volatile and intravenous anaesthetics for neurosurgical procedures...
  3. ncbi request reprint Direct comparison of B-type natriuretic peptide (BNP) and amino-terminal proBNP in a large population of patients with chronic and symptomatic heart failure: the Valsartan Heart Failure (Val-HeFT) data
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Clin Chem 52:1528-38. 2006
    ..This work aimed to provide a direct comparison of the prognostic value of BNP and NT-proBNP in patients with chronic and stable HF...
  4. doi request reprint Prognostic value of changes in N-terminal pro-brain natriuretic peptide in Val-HeFT (Valsartan Heart Failure Trial)
    Serge Masson
    Department of Cardiovascular Reearch, Istituto Mario Negri, Milan, Italy
    J Am Coll Cardiol 52:997-1003. 2008
    ..This study sought to evaluate the association between changes over time of N-terminal pro-brain natriuretic peptide (NT-proBNP) expressed in different ways and outcome in patients with stable and chronic heart failure (HF)...
  5. ncbi request reprint Clinical, neurohormonal, and inflammatory markers and overall prognostic role of chronic obstructive pulmonary disease in patients with heart failure: data from the Val-HeFT heart failure trial
    Lidia Staszewsky
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    J Card Fail 13:797-804. 2007
    ..Because little information is available about the population of patients with both syndromes, we assessed the characteristics and the independent contribution of COPD to outcomes in patients with stable chronic heart failure...
  6. ncbi request reprint Incremental prognostic value of changes in B-type natriuretic peptide in heart failure
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Am J Med 119:70.e23-30. 2006
    ..We hypothesized that B-type natriuretic peptide changes during treatment of heart failure may provide independent information on disease progression and outcome in patients enrolled in the Val-HeFT trial...
  7. ncbi request reprint Effect of beta-adrenergic and renin-angiotensin system blockade on myocyte apoptosis and oxidative stress in diabetic hypertensive rats
    Fabio Fiordaliso
    Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research, 20157 Milan, Italy
    Life Sci 81:951-9. 2007
    ..In conclusion, hypertensive rat is no more susceptible than its normotensive control to acute apoptosis induced by diabetes. Oxidative stress might be considered the common trigger for cardiac myocyte apoptosis in both conditions...
  8. ncbi request reprint The prognostic value of big endothelin-1 in more than 2,300 patients with heart failure enrolled in the Valsartan Heart Failure Trial (Val-HeFT)
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    J Card Fail 12:375-80. 2006
    ..Here, we examined its prognostic value in a large population of patients with chronic heart failure...
  9. ncbi request reprint The comparative prognostic value of plasma neurohormones at baseline in patients with heart failure enrolled in Val-HeFT
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur Heart J 25:292-9. 2004
    ..Mainly because of small sample size, the predictive value of different NH has never been compared, while taking into account demographic, clinical and echocardiographic markers of risk in HF...
  10. doi request reprint The predictive value of stable precursor fragments of vasoactive peptides in patients with chronic heart failure: data from the GISSI-heart failure (GISSI-HF) trial
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, Milan, Italy
    Eur J Heart Fail 12:338-47. 2010
    ..We measured the plasma concentrations of four stable precursor fragments of neurohormonal systems in patients with chronic HF and evaluated their relationship with outcome...
  11. doi request reprint Serial measurement of cardiac troponin T using a highly sensitive assay in patients with chronic heart failure: data from 2 large randomized clinical trials
    Serge Masson
    Department of Cardiovascular Research, Istituto Mario Negri, Via Giuseppe La Masa 19, 20156 Milan, Italy
    Circulation 125:280-8. 2012
    ..We determined the association between changes over time in hs-cTnT and outcome in patients with chronic HF...
  12. doi request reprint Left atrial remodeling and response to valsartan in the prevention of recurrent atrial fibrillation: the GISSI-AF echocardiographic substudy
    Lidia Staszewsky
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Circ Cardiovasc Imaging 4:721-8. 2011
    ..Angiotensin receptor blockers were proposed for reversing LA remodeling. We evaluated the effect of valsartan on LA remodeling in patients with a recent episode of AF and the effect of LA size on AF recurrence (AFr)...
  13. ncbi request reprint Neurohormonal modulation in heart failure of ischemic etiology: correlates with left ventricular remodeling
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Curr Heart Fail Rep 3:157-63. 2006
    ..Whether knowledge of biomarkers' concentration can improve the clinical outcome of patients with HF by helping in guiding and monitoring their therapy treatment is a stimulating working hypothesis still to be verified...
  14. doi request reprint Elevated plasma renin activity predicts adverse outcome in chronic heart failure, independently of pharmacologic therapy: data from the Valsartan Heart Failure Trial (Val-HeFT)
    Serge Masson
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    J Card Fail 16:964-70. 2010
    ..We evaluated the association between PRA and outcome in patients with chronic HF treated with ACEi and beta-blockers...
  15. doi request reprint Predictors of mortality in 6975 patients with chronic heart failure in the Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico-Heart Failure trial: proposal for a nomogram
    Simona Barlera
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Circ Heart Fail 6:31-9. 2013
    ..We developed a prognostic model to assess the risk of all-cause mortality in patients with chronic heart failure...
  16. ncbi request reprint Effects of valsartan on circulating brain natriuretic peptide and norepinephrine in symptomatic chronic heart failure: the Valsartan Heart Failure Trial (Val-HeFT)
    Roberto Latini
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Circulation 106:2454-8. 2002
    ..The long-term effects of angiotensin receptor blockers on BNP and NE in heart failure patients are not known...
  17. ncbi request reprint Valsartan for the treatment of heart failure
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche, Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Expert Opin Pharmacother 5:181-93. 2004
    ....
  18. ncbi request reprint Prognostic value of very low plasma concentrations of troponin T in patients with stable chronic heart failure
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Circulation 116:1242-9. 2007
    ..We assessed the prognostic value of circulating cardiac troponin T in patients with stable chronic HF with a traditional (cTnT) and a new precommercial highly sensitive assay (hsTnT)...
  19. ncbi request reprint Antioxidant treatment attenuates hyperglycemia-induced cardiomyocyte death in rats
    Fabio Fiordaliso
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milan, Italy
    J Mol Cell Cardiol 37:959-68. 2004
    ..NAC effectively protects from hyperglycemia-induced myocyte cell death and compensatory hypertrophy through direct scavenging of ROS and replenishment of the intracellular glutathione content...
  20. ncbi request reprint Significance of measurable cardiac troponin by high-sensitivity assays in patients with chronic stable heart failure
    Roberto Latini
    Department of Cardiovascular Research, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Coron Artery Dis 24:716-9. 2013
    ....
  21. ncbi request reprint Pentraxin-3 in chronic heart failure: the CORONA and GISSI-HF trials
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156 Milan, Italy
    Eur J Heart Fail 14:992-9. 2012
    ..Since the role of inflammation in the progression of chronic heart failure (HF) is debated, we investigated the prognostic value of PTX3 and the effect of a statin in two large populations of patients with HF...
  22. ncbi request reprint Eplerenone, a selective aldosterone blocker, improves diastolic function in aged rats with small-to-moderate myocardial infarction
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    J Card Fail 10:433-41. 2004
    ..05). Eplerenone normalized echocardiographic and hemodynamic evidences of diastolic dysfunction, as well as myocardial interstitial collagen and aortic fibrosis (all parameters statistically different from untreated MI)...
  23. doi request reprint Adiponectin in chronic heart failure: influence of diabetes and genetic variants
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur J Clin Invest 41:1330-8. 2011
    ..We also assessed the influence of these confounders on the prognostic value of adiponectin...
  24. doi request reprint Amino-terminal pro-B-type natriuretic peptides and prognosis in chronic heart failure
    Serge Masson
    Department of Cardiovascular Research, Laboratory of Cardiovascular Clinical Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Am J Cardiol 101:56-60. 2008
    ..Thus, serial assessment of NT-proBNP is valuable for prognostication in chronic HF in outpatients, and, as such, a measurement at each patient visit or the following of changes in clinical stability is recommended...
  25. ncbi request reprint In vivo cardioprotection by N-acetylcysteine and isosorbide 5-mononitrate in a rat model of ischemia-reperfusion
    Laura Calvillo
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milano
    Cardiovasc Drugs Ther 17:199-208. 2003
    ..We evaluated the effect of N-acetylcysteine (NAC, infused i.v.), isosorbide 5-mononitrate (IS5MN, by gavage), or their combination on cardiac injury in an in vivo rat model of 30-min ischemia followed by 24 hours or 7 days of reperfusion...
  26. ncbi request reprint Appraisal of the role of angiotensin II and aldosterone in ventricular myocyte apoptosis in adult normotensive rat
    Noeleen De Angelis
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri Milan, Italy
    J Mol Cell Cardiol 34:1655-65. 2002
    ....
  27. ncbi request reprint Role of brain natriuretic peptide in the diagnosis and management of heart failure: current concepts
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    J Card Fail 8:288-99. 2002
    ..Brain natriuretic peptide (BNP), a member of the natriuretic peptide family, has recently emerged as an important neurohormone in the pathophysiology of heart failure...
  28. doi request reprint Plasma n-3 polyunsaturated fatty acids in chronic heart failure in the GISSI-Heart Failure Trial: relation with fish intake, circulating biomarkers, and mortality
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Am Heart J 165:208-15.e4. 2013
    ..Circulating levels of n-3 PUFA, an objective estimation of exposure, have never been measured in a large cohort of patients with HF...
  29. ncbi request reprint Comparative measurement of N-terminal pro-brain natriuretic peptide and brain natriuretic peptide in ambulatory patients with heart failure
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Clin Chem Lab Med 40:761-3. 2002
    ..16 pM, ratio 24) and NT-proBNP (1306 vs. 57 pM, ratio 23). We conclude that N-terminal proBNP, as assayed in the present study, correlates equally to BNP with clinical variables in patients with heart failure...
  30. doi request reprint Levels of circulating pro-angiogenic cells predict cardiovascular outcomes in patients with chronic heart failure
    Giovanna Balconi
    Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research, Milano, Italy
    J Card Fail 15:747-55. 2009
    ..A low level of PACs is associated with worse outcome in patients with coronary heart disease. However, little is known about PACs in heart failure (HF)...
  31. doi request reprint Prevalence and prognostic value of elevated urinary albumin excretion in patients with chronic heart failure: data from the GISSI-Heart Failure trial
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Circ Heart Fail 3:65-72. 2010
    ..There is, however, only limited information on the prevalence and prognostic role of urinary albumin excretion in patients with established chronic heart failure...
  32. doi request reprint An update on cardiac troponins as circulating biomarkers in heart failure
    Serge Masson
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156, Milan, Italy
    Curr Heart Fail Rep 7:15-21. 2010
    ..In the absence of further experimental evidences, the pathophysiologic basis for the elevation of circulating cardiac troponins in patients with stable chronic heart failure remains speculative...
  33. doi request reprint Efficacy of aminaftone in a rat model of monocrotaline-induced pulmonary hypertension
    Vanessa Zambelli
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, 20156 Milano MI, Italy
    Eur J Pharmacol 667:287-91. 2011
    ..Aminaftone may represent a novel treatment strategy of pulmonary hypertension...
  34. ncbi request reprint Myocardial infarction: animal models
    Stefano Chimenti
    Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Methods Mol Med 98:217-26. 2004
    ..Moreover, this model allows testing of the protective effects of anti-inflammatory drugs in experimental myocardial infarction...
  35. ncbi request reprint Biomarkers of myocyte injury in heart failure
    Roberto Latini
    Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Heart Fail Clin 5:529-36. 2009
    ..The advent of a new generation of high-sensitivity immunoassays for cardiac troponins offers challenges for scientists and clinicians and will likely change the understanding and interpretation of cardiac injury...
  36. doi request reprint Early kynurenine pathway activation following cardiac arrest in rats, pigs, and humans
    Giuseppe Ristagno
    Department of Cardiovascular Research, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy Electronic address
    Resuscitation 84:1604-10. 2013
    ..In the present study, TRP and KP metabolites concentrations were measured in plasma from rats, pigs and humans after cardiac arrest (CA) in order to assess KP activation and its potential role in post-resuscitation outcome...
  37. doi request reprint Predicting atrial fibrillation recurrence with circulating inflammatory markers in patients in sinus rhythm at high risk for atrial fibrillation: data from the GISSI atrial fibrillation trial
    Serge Masson
    Department of Cardiovascular Research, Istituto Mario Negri, Via Giuseppe La Masa 19, Milan, Italy
    Heart 96:1909-14. 2010
    ..Inflammation may play a significant role in the pathogenesis of atrial fibrillation (AF)...
  38. doi request reprint Natriuretic peptides in acute chest pain and acute coronary syndrome: from pathophysiology to clinical and prognostic applications
    Nadia Aspromonte
    Cardiovascular Department, San Filippo Neri Hospital, Rome, Italy
    Coron Artery Dis 24:33-9. 2013
    ..Plasma levels of natriuretic peptides (NPs) appear to have an important prognostic value in many clinical settings including coronary artery disease and provide additional information about cardiovascular risk...
  39. ncbi request reprint Statins and symptomatic chronic systolic heart failure: a post-hoc analysis of 5010 patients enrolled in Val-HeFT
    Henry Krum
    NHMRC Centre of Clinical Research Excellence in Therapeutics, Monash University, Melbourne, Australia
    Int J Cardiol 119:48-53. 2007
    ..To address this, we retrospectively analyzed the Valsartan Heart Failure Trial (Val-HeFT) database to determine outcomes in CHF patients according to statin use at baseline...
  40. ncbi request reprint [Refractory heart failure. Antagonism of tumor necrosis factor alpha and endothelin in humans: 2 promises still to be honored]
    Marco Valgimigli
    Cattedra di Cardiologia, Universita degli Studi, Ferrara, e Centro di Fisiopatologia Cardiovascolare
    Ital Heart J Suppl 3:793-803. 2002
    ..The mechanisms by which TNF-alpha and ET might exert their negative biological actions are discussed together with an analysis of the possible reasons why they have failed so far in human CHF...
  41. ncbi request reprint [Recommendations for the clinical use of cardiac natriuretic peptides]
    Michele Emdin
    Istituto di Fisiologia Clinica del CNR, Pisa
    Ital Heart J Suppl 6:308-25. 2005
  42. ncbi request reprint [The AREA IN-CHF trial (antiremodeling effect of aldosterone receptors blockade with canrenone in mild chronic heart failure): rationale and design]
    Giuseppe Cacciatore
    U O C di Cardiologia, Azienda Ospedaliera San Giovanni Addolorata, Roma
    Ital Heart J 6:66S-74S. 2005
    ..Therefore it seems interesting to evaluate the effect of canrenone, an aldosterone receptor blocker, on the progression of left ventricular dysfunction in patients with mild heart failure assuming standard therapy...
  43. ncbi request reprint Usefulness of temporal changes in neurohormones as markers of ventricular remodeling and prognosis in patients with left ventricular systolic dysfunction and heart failure receiving either candesartan or enalapril or both
    Raymond T Yan
    The University Health Network, University of Toronto, Toronto, Ontario, Canada
    Am J Cardiol 96:698-704. 2005
    ..Serial measurements of these neurohormones may serve as useful surrogate markers of ventricular remodeling and prognosticators for clinical risk stratification...
  44. ncbi request reprint Baseline characteristics of patients recruited in the AREA IN-CHF study (Antiremodelling Effect of Aldosterone Receptors Blockade with Canrenone in Mild Chronic Heart Failure)
    Alessandro Boccanelli
    Department of Cardiology, San Giovanni Addolorata Hospital, Rome, Italy
    J Cardiovasc Med (Hagerstown) 8:683-91. 2007
    ..AREA IN-CHF was planned to investigate the effects of canrenone on progression of LV remodelling in mild HF...
  45. ncbi request reprint Changes in brain natriuretic peptide and norepinephrine over time and mortality and morbidity in the Valsartan Heart Failure Trial (Val-HeFT)
    Inder S Anand
    VA Medical Center and University of Minnesota, Minneapolis, Minn 55417, USA
    Circulation 107:1278-83. 2003
    ..We examined whether changes in brain natriuretic peptide (BNP) and norepinephrine (NE) over time are associated with corresponding changes in mortality and morbidity in the Valsartan Heart Failure Trial...
  46. ncbi request reprint Valsartan reduces the incidence of atrial fibrillation in patients with heart failure: results from the Valsartan Heart Failure Trial (Val-HeFT)
    Aldo P Maggioni
    ANMCO Research Center, Florence, Italy
    Am Heart J 149:548-57. 2005
    ..The aims of these subanalyses of Val-HeFT were to assess (a) the effects of valsartan in the prevention of AF, (b) the independent predictors of this event, and (c) the prognostic role of AF occurrence...
  47. ncbi request reprint Sustained reduction of aldosterone in response to the angiotensin receptor blocker valsartan in patients with chronic heart failure: results from the Valsartan Heart Failure Trial
    Jay N Cohn
    Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, 420 Delaware St SE, Minneapolis, Minn 55455, USA
    Circulation 108:1306-9. 2003
    ..The Valsartan Heart Failure Trial (Val-HeFT) provided the first opportunity to examine the long-term effects of an angiotensin receptor blocker on plasma aldosterone levels in patients with NYHA class II through IV heart failure...
  48. ncbi request reprint C-reactive protein in heart failure: prognostic value and the effect of valsartan
    Inder S Anand
    VA Medical Center, Minneapolis, MN 55417, USA
    Circulation 112:1428-34. 2005
    ..We assessed the prognostic value of CRP in patients randomized in Val-HeFT (Valsartan Heart Failure Trial) and studied changes in CRP that were associated with valsartan...
  49. ncbi request reprint Recommendations for the clinical use of cardiac natriuretic peptides
    Michele Emdin
    Institute of Clinical Physiology, National Research Council, Pisa, Italy
    Ital Heart J 6:430-46. 2005
  50. doi request reprint Lung injury and recovery in a murine model of unilateral acid aspiration: functional, biochemical, and morphologic characterization
    Maria Amigoni
    Department of Experimental Medicine, University of Milano Bicocca and Department of Perioperative Medicine and Intensive Care, San Gerardo Hospital, Monza, Italy
    Anesthesiology 108:1037-46. 2008
    ..Most animal models developed to define its pathophysiology have focused on the acute (< or =24 h) phase of the injury. The authors describe a model of acid aspiration allowing the study of this type of lung injury over time...
  51. doi request reprint Comparison of brain natriuretic peptide plasma levels versus logistic EuroSCORE in predicting in-hospital and late postoperative mortality in patients undergoing aortic valve replacement for symptomatic aortic stenosis
    Giovanni Battista Pedrazzini
    Division of Cardiology, Cardiocentro Ticino, Lugano, Switzerland
    Am J Cardiol 102:749-54. 2008
    ..In conclusion, in symptomatic patients with severe AS, high preoperative BNP plasma level and high logES confirm their predicting value for short- and long-term outcome...