Carla Marchetti

Summary

Affiliation: Istituto di Biofisica
Country: Italy

Publications

  1. pmc Role of calcium channels in heavy metal toxicity
    Carla Marchetti
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, 16149 Genova, Italy
    ISRN Toxicol 2013:184360. 2013
  2. doi request reprint Multiple effects of copper on NMDA receptor currents
    Carla Marchetti
    Institute of Biophysics, National Research Council, Genova, Italy Electronic address
    Brain Res 1542:20-31. 2014
  3. doi request reprint South African plants used in traditional medicine to treat epilepsy have an antagonistic effect on NMDA receptor currents
    Carla Marchetti
    Institute of Biophysics, National Research Council, Via De Marini 6, 16149 Genova, Italy
    J Ethnopharmacol 137:382-8. 2011
  4. doi request reprint Molecular determinants of multiple effects of nickel on NMDA receptor channels
    Paola Gavazzo
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Via De Marini, 6, 16149 Genoa, Italy
    Neurotox Res 15:38-48. 2009
  5. ncbi request reprint Nickel differentially affects NMDA receptor channels in developing cultured rat neurons
    Paola Gavazzo
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Via De Marini, 6, 16149 Genova, Italy
    Brain Res 1078:71-9. 2006
  6. ncbi request reprint NMDA receptors as targets of heavy metal interaction and toxicity
    Carla Marchetti
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, 16149 Genoa, Italy
    Neurotox Res 8:245-58. 2005
  7. doi request reprint The influence of calcium ions on nickel modulation of NMDA receptor currents
    Paola Gavazzo
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Genova, Italy
    Metallomics 3:1376-83. 2011
  8. ncbi request reprint Molecular determinants of Pb2+ interaction with NMDA receptor channels
    Paola Gavazzo
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Via De Marini 6, 16149 Genova, Italy
    Neurochem Int 52:329-37. 2008
  9. ncbi request reprint Subunit-dependent effects of nickel on NMDA receptor channels
    Carla Marchetti
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Via De Marini, 6, 16149 Genova, Italy
    Brain Res Mol Brain Res 117:139-44. 2003
  10. ncbi request reprint Two-photon analysis of lead accumulation in rat cerebellar granule neurons
    Alessandro Esposito
    INFM, Dipartimento di Fisica, Universita di Genova, Via Dodecaneso, 33, 16146, Genova, Italy
    Neurochem Res 30:949-54. 2005

Detail Information

Publications12

  1. pmc Role of calcium channels in heavy metal toxicity
    Carla Marchetti
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, 16149 Genova, Italy
    ISRN Toxicol 2013:184360. 2013
    ....
  2. doi request reprint Multiple effects of copper on NMDA receptor currents
    Carla Marchetti
    Institute of Biophysics, National Research Council, Genova, Italy Electronic address
    Brain Res 1542:20-31. 2014
    ..These results indicate that Cu can facilitate the NR current at lower concentrations than those required for blocking it; this effect can have consequences on the activity of the metal at synaptic and extrasynaptic sites...
  3. doi request reprint South African plants used in traditional medicine to treat epilepsy have an antagonistic effect on NMDA receptor currents
    Carla Marchetti
    Institute of Biophysics, National Research Council, Via De Marini 6, 16149 Genova, Italy
    J Ethnopharmacol 137:382-8. 2011
    ..Ethanol leaf extracts of these plants have been shown to act as possible antagonists of N-methyl-d-aspartate (NMDA)-type glutamate receptors...
  4. doi request reprint Molecular determinants of multiple effects of nickel on NMDA receptor channels
    Paola Gavazzo
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Via De Marini, 6, 16149 Genoa, Italy
    Neurotox Res 15:38-48. 2009
    ..The block was also partially, but not as prominently, reduced by the double mutation H705AH709A in the same region of NR1. This additional binding site can be responsible of specific heavy metal interaction with NR channels...
  5. ncbi request reprint Nickel differentially affects NMDA receptor channels in developing cultured rat neurons
    Paola Gavazzo
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Via De Marini, 6, 16149 Genova, Italy
    Brain Res 1078:71-9. 2006
    ..All these data indicate that Ni(2+) is a suitable marker for the identification of NR2A and NR2B native channel subunits and can be used to trace the development of NMDA receptor composition...
  6. ncbi request reprint NMDA receptors as targets of heavy metal interaction and toxicity
    Carla Marchetti
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, 16149 Genoa, Italy
    Neurotox Res 8:245-58. 2005
    ..The NR2B-dependent facilitation bears close similarities with the polyamine-mediated potentiation...
  7. doi request reprint The influence of calcium ions on nickel modulation of NMDA receptor currents
    Paola Gavazzo
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Genova, Italy
    Metallomics 3:1376-83. 2011
    ....
  8. ncbi request reprint Molecular determinants of Pb2+ interaction with NMDA receptor channels
    Paola Gavazzo
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Via De Marini 6, 16149 Genova, Italy
    Neurochem Int 52:329-37. 2008
    ....
  9. ncbi request reprint Subunit-dependent effects of nickel on NMDA receptor channels
    Carla Marchetti
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Via De Marini, 6, 16149 Genova, Italy
    Brain Res Mol Brain Res 117:139-44. 2003
    ..These results indicate that Ni2+ has multiple and complex effects on NMDA channels, which are largely dependent on the NR2 subunit...
  10. ncbi request reprint Two-photon analysis of lead accumulation in rat cerebellar granule neurons
    Alessandro Esposito
    INFM, Dipartimento di Fisica, Universita di Genova, Via Dodecaneso, 33, 16146, Genova, Italy
    Neurochem Res 30:949-54. 2005
    ..Intracellular Pb2+ concentrations were evaluated from the fluorescence intensity and this estimate indicated that the concentration of free Pb2+ sufficient to inactivate the transport system is close to 50 pM...
  11. doi request reprint Acquisition of neuron-like electrophysiological properties in neuroblastoma cells by controlled expression of NDM29 ncRNA
    Paola Gavazzo
    Institute of Biophysics, CNR, Genoa, Italy
    J Neurochem 119:989-1001. 2011
    ..In this context, S1 cells may represent a novel in vitro tool for electrophysiological and pharmacological studies of human cells of the neural lineage...
  12. ncbi request reprint Susceptibility of insulinoma cells to cadmium and modulation by L-type calcium channels
    Paola Gavazzo
    Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Via De Marini, 6 16149 Genova, Italy
    Biometals 18:131-42. 2005
    ..These data demonstrate a specific sensitivity to Cd of insulinoma cells that can be significant for pancreatic beta-cell pathology...