Research Topics
| Emilia MarcheiSummaryAffiliation: Istituto Superiore di Sanit Country: Italy Publications
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Detail Information
Publications
Development and validation of a high-performance liquid chromatography-mass spectrometry assay for methylxanthines and taurine in dietary supplementsEmilia Marchei
Drug Research and Evaluation Department, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Rome, Italy
J Pharm Biomed Anal 37:499-507. 2005..Conversely, herbal powders, tablets and capsules mainly contained mg amounts of caffeine per gram of product with the other two methylxanthines in the range of ten to hundred microg/g...- Assessment of exposure to opiates and cocaine during pregnancy in a Mediterranean city: preliminary results of the "Meconium Project"Simona Pichini
Drug Research and Evaluation Department, Istituto Superiore di Sanit, Rome, Italy
Forensic Sci Int 153:59-65. 2005..Of the four newborns exposed to arecoline, one showed a low birth weight, low intrauterine growth, hyporeflexia and hypotonia... 
Hair and urine testing to assess drugs of abuse consumption in couples undergoing assisted reproductive technology (ART)Simona Pichini
Drug Research and Evaluation Department, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Rome, Italy
Forensic Sci Int 218:57-61. 2012..Association between different toxic habits and sedentary lifestyle is also substantiated by the obtained results in our cohort of couples attending assisted reproduction centers...- Assessment of prenatal exposure to ethanol by meconium analysis: results of an Italian multicenter studySimona Pichini
Istituto Superiore di Sanita, Roma, Italy
Alcohol Clin Exp Res 36:417-24. 2012.... - Ethylglucuronide and ethylsulfate in meconium to assess gestational ethanol exposure: preliminary results in two Mediterranean cohortsSimona Pichini
1Department of Therapeutic Research and Medicine Evaluation, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Roma, Italy
Can J Clin Pharmacol 16:e370-5. 2009..Among the minor nonoxidative products of ethanol metabolism, there are ethyl glucuronide (EtG) and ethyl sulfate (EtS)... - Liquid chromatography-tandem mass spectrometry for fatty acid ethyl esters in meconium: assessment of prenatal exposure to alcohol in two European cohortsSimona Pichini
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
J Pharm Biomed Anal 48:927-33. 2008..6 and 86.7% for the different analytes. The validated method was applied to analysis of meconium in newborns of two European cities. The two cohorts presented with different prevalence of gestational ethanol consumption during pregnancy... - Usefulness of sweat testing for the detection of methylphenidate after fast- and extended-release drug administration: a pilot studyEmilia Marchei
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
Ther Drug Monit 32:508-11. 2010..RA was not detected in either of the sweat patches probably because of its acidic properties. Measuring MPH in sweat patches can be a viable alternative to urine testing for noninvasive monitoring of use and misuse of the drug... - Liquid chromatography-electrospray ionization mass spectrometry determination of methylphenidate and ritalinic acid in conventional and non-conventional biological matricesEmilia Marchei
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, 00161 Rome, Italy
J Pharm Biomed Anal 49:434-9. 2009..9-90.3% for MPH and 36.3-92.4% for RA in the different biological matrices. This method was applied to therapeutic monitoring of MHP and RA in conventional and non-conventional biological matrices from individuals in drug treatment... - Liquid chromatography-atmospheric pressure ionization electrospray mass spectrometry determination of "hallucinogenic designer drugs" in urine of consumersSimona Pichini
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
J Pharm Biomed Anal 47:335-42. 2008..4 and 95.6% for the different analytes. Higher analytes concentrations in hydrolyzed samples showed the presence of conjugated compounds in urine... - Development and validation of a gas chromatography-mass spectrometry assay for opiates and cocaine in human teethManuela Pellegrini
Drug Research and Control Department, Istituto Superiore di Sanit, V.le Regina Elena 299, 00161 Rome, Italy
J Pharm Biomed Anal 40:662-8. 2006..6 to 81.7 ng/g and cocaethylene present in only one sample at 10 ng/g value. Teeth can be a promising non-invasive biological matrix in biomedical analysis for both clinical and forensic purposes... - A rapid and simple procedure for the determination of ephedrine alkaloids in dietary supplements by gas chromatography-mass spectrometryEmilia Marchei
Drug Control and Evaluation Department, Istituto Superiore di Sanit, V.le Regina Elena 299, 00161 Rome, Italy
J Pharm Biomed Anal 41:1633-41. 2006..The method was applied to analysis of various dietary supplements containing Ma-huang (Ephedra Sinica) and Sida Cordifolia plant extracts promoted for aiding weight control and boosting sports performance and energy... - Correlation between methylphenidate and ritalinic acid concentrations in oral fluid and plasmaEmilia Marchei
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
Clin Chem 56:585-92. 2010..We studied the excretion profile of methylphenidate (MPH) and its metabolite ritalinic acid (RA) in oral fluid and plasma, the oral fluid-to-plasma (OF/P) drug ratio, and the variations of oral fluid pH after drug administration... - Quantification of Delta9-tetrahydrocannabinol and its major metabolites in meconium by gas chromatographic-mass spectrometric assay: assay validation and preliminary results of the "meconium project"Emilia Marchei
Drug Research and Evaluation Department, Istituto Superiore di Sanit, V.le Regina Elena 299, 00161 Rome, Italy
Ther Drug Monit 28:700-6. 2006..Within positive samples, THC-COOH and THC-OH (range: 33.7 to 182.1 and 20.7 to 493.3 microg/g, respectively) were both present in the majority of cases with only 1 specimen with THC-OH as the most abundant metabolite and 2 with THC only... - High-performance liquid chromatography-diode array and electrospray-mass spectrometry analysis of non-allowed substances in cosmetic products for preventing hair loss and other hormone-dependent skin diseasesDaniela De Orsi
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Rome, Italy
J Pharm Biomed Anal 48:641-8. 2008.... - Liquid chromatography/electrospray ionization tandem mass spectrometry assay for determination of nicotine and metabolites, caffeine and arecoline in breast milkManuela Pellegrini
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
Rapid Commun Mass Spectrom 21:2693-703. 2007..This LC/MS/MS assay provides adequate sensitivity and performance characteristics for the simultaneous quantification of biomarkers of three of the drugs most commonly used worldwide (tobacco, caffeine and areca nut)... - Determination of atomoxetine and its metabolites in conventional and non-conventional biological matrices by liquid chromatography-tandem mass spectrometryEmilia Marchei
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
J Pharm Biomed Anal 60:26-31. 2012..This method was applied to therapeutic monitoring of ATX and its metabolites 4-OH-ATX and N-des-ATX in conventional and non-conventional biological matrices from individuals in drug treatment... - Advances in the analysis of non-allowed pharmacologically active substances in cosmetic productsManuela Pellegrini
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Rome, Italy
J Pharm Biomed Anal 55:842-7. 2011.... - Simultaneous analysis of frequently used licit and illicit psychoactive drugs in breast milk by liquid chromatography tandem mass spectrometryEmilia Marchei
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
J Pharm Biomed Anal 55:309-16. 2011.... - Quantification of the plant-derived hallucinogen Salvinorin A in conventional and non-conventional biological fluids by gas chromatography/mass spectrometry after Salvia divinorum smokingSimona Pichini
Drug Research and Evaluation Department, Istituto Superiore di Sanità Rome, Italy
Rapid Commun Mass Spectrom 19:1649-56. 2005..divinorum in human biological fluids as a biomarker of plant consumption. Salvinorin A was detected in urine (2.4 and 10.9 ng/mL) and saliva (11.1 and 25.0 ng/mL), but not in sweat patches from consumers... - High performance liquid chromatography-diode array and electrospray-mass spectrometry analysis of vardenafil, sildenafil, tadalafil, testosterone and local anesthetics in cosmetic creams sold on the Internet web sitesDaniela De Orsi
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, V le Regina Elena 299, 00161, Rome, Italy
J Pharm Biomed Anal 50:362-9. 2009..This method was successfully applied to the analysis of substances under investigations present in cosmetic creams, freely sold on the Internet web-sites... - Quantification of arecoline (areca nut alkaloid) in neonatal biological matrices by high-performance liquid chromatography/electrospray quadrupole mass spectrometrySimona Pichini
Drug Research and Control Department, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Rome, Italy
Rapid Commun Mass Spectrom 17:1958-64. 2003..Two newborns from Asian mothers who declared areca nut consumption presented arecoline in meconium with concentrations in the range 0.006-0.008 micro g/g; also the urine from one neonate tested positive for the drug... - A rapid and simple procedure for the determination of cannabinoids in hemp food products by gas chromatography-mass spectrometryManuela Pellegrini
Drug Research and Control Department, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Rome, Italy
J Pharm Biomed Anal 36:939-46. 2005..Products possibly originating from drug-type cannabis plants were found in the majority of analyzed specimens... - Nonnucleoside reverse transcriptase inhibitor concentrations during treatment interruptions and the emergence of resistance: a substudy of the ISS-PART TrialMaria Pirillo
Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Rome, Italy
AIDS Res Hum Retroviruses 26:541-5. 2010.... - 3,4-methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically exposed to cocaineOscar Garcia-Algar
Paediatric Service, Hospital del Mar, Barcelona, Spain
Ther Drug Monit 27:409-11. 2005..Periodic clinical and laboratory follow-ups were requested to check eventual long-term effects of exposure to illicit drugs and discontinuation of the child from exposure to dangerous environments... - Prevalence of gestational exposure to cannabis in a Mediterranean city by meconium analysisJaime Lozano
Unitat de Recerca Infància i Entorn URIE, Paediatric Service, Hospital del Mar, and Departament de Pediatria, Ginecologia i Obstetrica, i Medicina Preventiva, Universitat Autonoma, Barcelona, Spain
Acta Paediatr 96:1734-7. 2007..To investigate the prevalence of in utero exposure to cannabis in a cohort of 974 mother-infants dyads from Barcelona (Spain)... - Ultrasensitive detection of nicotine and cotinine in teeth by high-performance liquid chromatography/tandem mass spectrometryEmilia Marchei
Rapid Commun Mass Spectrom 22:2609-12. 2008 - Determination of arecoline (areca nut alkaloid) and nicotine in hair by high-performance liquid chromatography/electrospray quadrupole mass spectrometryEmilia Marchei
Rapid Commun Mass Spectrom 19:3416-8. 2005 - Neonatal withdrawal syndrome after chronic maternal drinking of mateItziar Martin
Neonatology Unit, Service of Pediatrics, Hospital Universitari del Mar, Barcelona, Spain
Ther Drug Monit 29:127-9. 2007..The mother was strongly advised to initiate a considerable, progressive, constant reduction of mate consumption to a maximum of 2 cups a day for the duration of breastfeeding... - A rapid and simple procedure for the determination of synephrine in dietary supplements by gas chromatography-mass spectrometryEmilia Marchei
Drug Control and Evaluation Department, Istituto Superiore di Sanit, V.le Regina Elena 299, 00161, Rome, Italy
J Pharm Biomed Anal 41:1468-72. 2006..Amount of synephrine present in such products ranged from 3.1 microg/mg solid product to 480.2 microg/mL liquid product... - Simultaneous determination of zidovudine and nevirapine in human plasma by RP-LCEmilia Marchei
Istituto Superiore di Sanit, Viale Regina Elena 299, Rome, Italy
J Pharm Biomed Anal 29:1081-8. 2002..Extraction recoveries are higher than 90% for both zidovudine and nevirapine. The method proposed was employed to determine the levels of the two retroviral drugs in plasma from HIV infected human subjects...