Ugo Lucca

Summary

Affiliation: Istituto di Ricerche Farmacologiche Mario Negri
Country: Italy

Publications

  1. doi request reprint Prevalence of dementia in the oldest old: The Monzino 80-plus population based study
    Ugo Lucca
    Department of Neuroscience, Laboratory of Geriatric Neuropsychiatry, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy Electronic address
    Alzheimers Dement 11:258-270.e3. 2015
  2. pmc A Population-based study of dementia in the oldest old: the Monzino 80-plus study
    Ugo Lucca
    Laboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    BMC Neurol 11:54. 2011
  3. pmc Association of mild anemia with cognitive, functional, mood and quality of life outcomes in the elderly: the "Health and Anemia" study
    Ugo Lucca
    Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    PLoS ONE 3:e1920. 2008
  4. doi request reprint Cholinesterase inhibitor use in Alzheimer's disease: the EPIFARM-Elderly Project
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Pharmacoepidemiol Drug Saf 20:497-505. 2011
  5. pmc Prevalence, incidence and types of mild anemia in the elderly: the "Health and Anemia" population-based study
    Mauro Tettamanti
    Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156 Milan, Italy
    Haematologica 95:1849-56. 2010
  6. pmc Association of mild anemia with hospitalization and mortality in the elderly: the Health and Anemia population-based study
    Emma Riva
    Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    Haematologica 94:22-8. 2009
  7. doi request reprint Changes in trend of antipsychotics prescription in patients treated with cholinesterase inhibitors after warnings from Italian Medicines Agency. Results from the EPIFARM-Elderly Project
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Eur Neuropsychopharmacol 22:569-77. 2012
  8. pmc Interleukin-1α, interleukin-1β and tumor necrosis factor-α genetic variants and risk of dementia in the very old: evidence from the "Monzino 80-plus" prospective study
    Diego Albani
    Laboratory of Biology of Neurodegenerative Disorders, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Age (Dordr) 34:519-26. 2012
  9. ncbi request reprint Low folate and the risk of cognitive and functional deficits in the very old: the Monzino 80-plus study
    Mauro Tettamanti
    Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
    J Am Coll Nutr 25:502-8. 2006
  10. ncbi request reprint Use and misuse of antipsychotic drugs in patients with dementia in Alzheimer special care units
    Alessandro Nobili
    Laboratory of Quality Assessment of Geriatric Therapies and Services, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, Milan 20156, Italy
    Int Clin Psychopharmacol 24:97-104. 2009

Collaborators

Detail Information

Publications22

  1. doi request reprint Prevalence of dementia in the oldest old: The Monzino 80-plus population based study
    Ugo Lucca
    Department of Neuroscience, Laboratory of Geriatric Neuropsychiatry, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy Electronic address
    Alzheimers Dement 11:258-270.e3. 2015
    ..The objective is to estimate the prevalence of dementia and levels of dementia severity in a very large population of oldest old and to investigate the relation between age and dementia prevalence in the extreme ages...
  2. pmc A Population-based study of dementia in the oldest old: the Monzino 80-plus study
    Ugo Lucca
    Laboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    BMC Neurol 11:54. 2011
    ....
  3. pmc Association of mild anemia with cognitive, functional, mood and quality of life outcomes in the elderly: the "Health and Anemia" study
    Ugo Lucca
    Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    PLoS ONE 3:e1920. 2008
    ..The objective of the present study was to cross-sectionally investigate the association of mild grade anemia with cognitive, functional, mood, and quality of life (QoL) variables in community-dwelling elderly persons...
  4. doi request reprint Cholinesterase inhibitor use in Alzheimer's disease: the EPIFARM-Elderly Project
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Pharmacoepidemiol Drug Saf 20:497-505. 2011
    ....
  5. pmc Prevalence, incidence and types of mild anemia in the elderly: the "Health and Anemia" population-based study
    Mauro Tettamanti
    Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156 Milan, Italy
    Haematologica 95:1849-56. 2010
    ..The objectives of this study were to estimate the prevalence and incidence of mild grade anemia and to assess the frequency of anemia types in the elderly...
  6. pmc Association of mild anemia with hospitalization and mortality in the elderly: the Health and Anemia population-based study
    Emma Riva
    Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    Haematologica 94:22-8. 2009
    ..The aim of the present population-based study was to prospectively investigate the association of mild grade anemia with hospitalization and mortality...
  7. doi request reprint Changes in trend of antipsychotics prescription in patients treated with cholinesterase inhibitors after warnings from Italian Medicines Agency. Results from the EPIFARM-Elderly Project
    Carlotta Franchi
    Laboratory for Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Eur Neuropsychopharmacol 22:569-77. 2012
    ..Awaiting further studies to clarify their therapeutic role, physicians should prescribe antipsychotics very cautiously and only after careful risk-benefit assessment...
  8. pmc Interleukin-1α, interleukin-1β and tumor necrosis factor-α genetic variants and risk of dementia in the very old: evidence from the "Monzino 80-plus" prospective study
    Diego Albani
    Laboratory of Biology of Neurodegenerative Disorders, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Age (Dordr) 34:519-26. 2012
    ..26), which was an independent predictor of dementia onset (p = 0.0002). In short, in this Italian population of oldest olds, dementia was associated to the APOE-ε4 allele only...
  9. ncbi request reprint Low folate and the risk of cognitive and functional deficits in the very old: the Monzino 80-plus study
    Mauro Tettamanti
    Laboratory of Geriatric Neuropsychiatry, Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
    J Am Coll Nutr 25:502-8. 2006
    ..To cross sectionally investigate the association of serum vitamin B(12) and folate concentrations with cognitive and functional ability in the very old in the general population...
  10. ncbi request reprint Use and misuse of antipsychotic drugs in patients with dementia in Alzheimer special care units
    Alessandro Nobili
    Laboratory of Quality Assessment of Geriatric Therapies and Services, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, Milan 20156, Italy
    Int Clin Psychopharmacol 24:97-104. 2009
    ..61-3.26). This study found high rate of use of antipsychotics in patients with dementia resident in Alzheimer special care units, frequent associations with other psychotropic medications and a strong correlation with BPSD...
  11. doi request reprint The serotonin transporter promoter polymorphic region is not a risk factor for Alzheimer's disease related behavioral disturbances
    Diego Albani
    Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Milan, Italy
    J Alzheimers Dis 18:125-30. 2009
    ..We conclude that 5-HTTLPR and rs25531 are not major genetic modulators of BPSD development in AD...
  12. doi request reprint The SIRT2 polymorphism rs10410544 and risk of Alzheimer's disease in two Caucasian case-control cohorts
    Letizia Polito
    Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Milan, Italy Golgi Cenci Foundation, Abbiategrasso, Italy
    Alzheimers Dement 9:392-9. 2013
    ..This study investigated whether genetic variants in two members of the sirtuin family, SIRT2 and SIRT3, affected AD susceptibility...
  13. doi request reprint Drug utilization and polypharmacy in an Italian elderly population: the EPIFARM-elderly project
    Alessandro Nobili
    Laboratory of Quality Assessment of Geriatric Therapies and Services, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Pharmacoepidemiol Drug Saf 20:488-96. 2011
    ..To investigate the prescribing patterns and the prevalence of polypharmacy in community-dwelling elderly people, and to analyze the association of chronic medications and number of drug prescriptions with age and sex...
  14. ncbi request reprint The effect of a structured intervention on caregivers of patients with dementia and problem behaviors: a randomized controlled pilot study
    Alessandro Nobili
    Geriatric Neuropsychiatry Laboratory, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Alzheimer Dis Assoc Disord 18:75-82. 2004
    ..The number of families lost to follow-up, the relatively short duration of the study, and the ceiling effect due to the severity of the clinical characteristics of patients probably all partly dilute the observed findings...
  15. ncbi request reprint Role of VEGF gene variability in longevity: a lesson from the Italian population
    Roberto Del Bo
    Department of Neurological Sciences, Dino Ferrari Centre, University of Milan, IRCCS Foundation Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Padiglione Ponti, Milano, Italy
    Neurobiol Aging 29:1917-22. 2008
    ..These results suggest that VEGF gene variability can be inserted among the genetic factors influencing the lifespan...
  16. doi request reprint Alzheimer special care units compared with traditional nursing home for dementia care: are there differences at admission and in clinical outcomes?
    Alessandro Nobili
    Laboratory of Quality Assessment of Geriatric Therapies and Services for the Elderly, Lombardy Region, Italy
    Alzheimer Dis Assoc Disord 22:352-61. 2008
    ..Studies comparing Alzheimer Special Care Units (ASCUs) with traditional nursing homes (NHs) have reported conflicting results...
  17. ncbi request reprint Tumor necrosis factor alpha polymorphism C-850T is not associated with Alzheimer's disease and vascular dementia in an Italian population
    Liana Terreni
    Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Neurosci Lett 344:135-7. 2003
    ..The influence of TNF-alpha polymorphism on dementia has not been confirmed in this segment of the Italian population...
  18. ncbi request reprint Homocysteine and B vitamins in mild cognitive impairment and dementia
    Pierluigi Quadri
    Geriatric Division and Department of Metabolic Diseases, Ospedale Regionale della Beata Vergine, Mendrisio, Switzerland
    Clin Chem Lab Med 43:1096-100. 2005
    ..6). Present reanalysis results suggest that subclinical folate deficiency and hyperhomocysteinemia might predate dementia onset, findings to be confirmed by longitudinal studies...
  19. ncbi request reprint Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia
    Pierluigi Quadri
    Memory Clinic, Geriatric Division and Department of Metabolic Diseases, Ospedale Regionale della Beata Vergine, Mendrisio, Switzerland
    Am J Clin Nutr 80:114-22. 2004
    ..Recent epidemiologic studies reappraised the possibility that vascular risk factors might play a role in the pathogenesis not only of vascular dementia (VaD) but also of Alzheimer disease (AD)...
  20. doi request reprint The Italian version of Consortium to Establish a Registry of Alzheimer's Disease (CERAD)
    Ugo Lucca
    Alzheimers Dement 4:310. 2008
  21. ncbi request reprint Homocysteine lowering and cognitive performance
    Ugo Lucca
    N Engl J Med 355:1390; author reply 1391. 2006
  22. ncbi request reprint Peripheral biomarkers of oxidative damage in Alzheimer's disease
    Chiara Chiabrando
    Ann Neurol 53:419-20; author reply 420. 2003