T Granata

Summary

Affiliation: Istituto Nazionale Neurologico Carlo Besta
Country: Italy

Publications

  1. ncbi request reprint Rasmussen's encephalitis: early characteristics allow diagnosis
    T Granata
    Division of Child Neurology, Istituto Nazionale Neurologico C Besta, Milan, Italy
    Neurology 60:422-5. 2003
  2. doi request reprint Rasmussen encephalitis
    Tiziana Granata
    Department of Pediatric Neuroscience, Carlo Besta Neurological Institute, Milan, Italy Electronic address
    Handb Clin Neurol 111:511-9. 2013
  3. ncbi request reprint Schizencephaly: clinical spectrum, epilepsy, and pathogenesis
    Tiziana Granata
    Division of Child Neurology, IRCCS Istituto Nazionale Neurologico C Besta, Milan, Italy
    J Child Neurol 20:313-8. 2005
  4. doi request reprint Comprehensive care of children with Dravet syndrome
    Tiziana Granata
    Department of Pediatric Neuroscience, IRCCS Foundation Neurological Institute C Besta, Milano, Italy
    Epilepsia 52:90-4. 2011
  5. pmc Immune-mediated epilepsies
    Tiziana Granata
    Department of Child Neurology, Carlo Besta Neurological Institute, Milan, Italy
    Epilepsia 52:5-11. 2011
  6. doi request reprint Epilepsy in type 1 Chiari malformation
    Tiziana Granata
    Department of Paediatric Neuroscience, IRCCS Foundation Neurological Institute C Besta, Via Celoria 11, 20133, Milan, Italy
    Neurol Sci 32:S303-6. 2011
  7. ncbi request reprint Experience with immunomodulatory treatments in Rasmussen's encephalitis
    T Granata
    Division of Child Neurology, Istituto Nazionale Neurologico C Besta, Milan, Italy
    Neurology 61:1807-10. 2003
  8. ncbi request reprint Diagnostic imaging in 13 cases of Rasmussen's encephalitis: can early MRI suggest the diagnosis?
    L Chiapparini
    Department of Neuroradiology, Istituto Nazionale Neurologico C Besta, Via Celoria 11, 20133 Milano, Italy
    Neuroradiology 45:171-83. 2003
  9. ncbi request reprint Positive response to immunomodulatory therapy in an adult patient with Rasmussen's encephalitis
    F Villani
    Division of Clinical Neurophysiology and Epileptology, Istituto Nazionale Neurologico C Besta, Milan, Italy
    Neurology 56:248-50. 2001
  10. ncbi request reprint Labeling of rat neurons by anti-GluR3 IgG from patients with Rasmussen encephalitis
    C Frassoni
    Department of Experimental Neurophysiology and Epileptology, Istituto Nazionale Neurologico Carlo Besta, Milan, Italy
    Neurology 57:324-7. 2001

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Rasmussen's encephalitis: early characteristics allow diagnosis
    T Granata
    Division of Child Neurology, Istituto Nazionale Neurologico C Besta, Milan, Italy
    Neurology 60:422-5. 2003
    ..To identify early manifestations of Rasmussen encephalitis (RE) that can prompt early and reasonably secure diagnosis, allowing medical or surgical therapies at an early stage when they may be more effective in slowing the disease...
  2. doi request reprint Rasmussen encephalitis
    Tiziana Granata
    Department of Pediatric Neuroscience, Carlo Besta Neurological Institute, Milan, Italy Electronic address
    Handb Clin Neurol 111:511-9. 2013
    ..Given that the severity of symptoms varies among different patients and phases, the therapeutic strategy, including medical and surgical options, must be tailored to the need of each patient...
  3. ncbi request reprint Schizencephaly: clinical spectrum, epilepsy, and pathogenesis
    Tiziana Granata
    Division of Child Neurology, IRCCS Istituto Nazionale Neurologico C Besta, Milan, Italy
    J Child Neurol 20:313-8. 2005
    ....
  4. doi request reprint Comprehensive care of children with Dravet syndrome
    Tiziana Granata
    Department of Pediatric Neuroscience, IRCCS Foundation Neurological Institute C Besta, Milano, Italy
    Epilepsia 52:90-4. 2011
    ....
  5. pmc Immune-mediated epilepsies
    Tiziana Granata
    Department of Child Neurology, Carlo Besta Neurological Institute, Milan, Italy
    Epilepsia 52:5-11. 2011
    ..We highlight future directions for preclinical and clinical research that are required for improved diagnosis and treatment of immune-mediated epilepsies...
  6. doi request reprint Epilepsy in type 1 Chiari malformation
    Tiziana Granata
    Department of Paediatric Neuroscience, IRCCS Foundation Neurological Institute C Besta, Via Celoria 11, 20133, Milan, Italy
    Neurol Sci 32:S303-6. 2011
    ..Epileptic seizures must be accurately differentiated by potentially harmful paroxysmal events due to compression of the medulla, particularly by the cerebellar fits characterized by drop attacks, abnormal extensor posturing and apnea...
  7. ncbi request reprint Experience with immunomodulatory treatments in Rasmussen's encephalitis
    T Granata
    Division of Child Neurology, Istituto Nazionale Neurologico C Besta, Milan, Italy
    Neurology 61:1807-10. 2003
    ....
  8. ncbi request reprint Diagnostic imaging in 13 cases of Rasmussen's encephalitis: can early MRI suggest the diagnosis?
    L Chiapparini
    Department of Neuroradiology, Istituto Nazionale Neurologico C Besta, Via Celoria 11, 20133 Milano, Italy
    Neuroradiology 45:171-83. 2003
    ..Early diagnosis of RE may be crucial for selecting patients for aggressive medical therapy or major surgical interventions such as hemispherectomy...
  9. ncbi request reprint Positive response to immunomodulatory therapy in an adult patient with Rasmussen's encephalitis
    F Villani
    Division of Clinical Neurophysiology and Epileptology, Istituto Nazionale Neurologico C Besta, Milan, Italy
    Neurology 56:248-50. 2001
    ..High-dose corticosteroids and plasmapheresis were not effective. She improved with high-dose therapy with human IV immunoglobulin...
  10. ncbi request reprint Labeling of rat neurons by anti-GluR3 IgG from patients with Rasmussen encephalitis
    C Frassoni
    Department of Experimental Neurophysiology and Epileptology, Istituto Nazionale Neurologico Carlo Besta, Milan, Italy
    Neurology 57:324-7. 2001
    ..These findings show that anti-GluR3 antibodies purified from patients with RE bind to specific regions of the CNS but do not act through an excitotoxic mechanism...
  11. ncbi request reprint Epileptic phenotypes associated with mitochondrial disorders
    L Canafoglia
    Department of Clinical Neurophysiology, Epilepsy Center, Istituto Nazionale Neurologico C. Besta, Milan, Italy
    Neurology 56:1340-6. 2001
    ..Except for those with an A8344G mitochondrial DNA point mutation, most of our patients had partial seizures or EEG signs indicating a focal origin...
  12. ncbi request reprint Spectral properties of EEG fast activity ictal discharges associated with infantile spasms
    F Panzica
    Department of Neurophysiology, C Besta Neurological Institute, Milan, Italy
    Clin Neurophysiol 110:593-603. 1999
    ..The aim of this study was to evaluate the characteristics of the ictal EEG event accompanying infantile spasms...
  13. ncbi request reprint Subcortical nodular heterotopia: a functional MRI and somatosensory evoked potentials study
    F Villani
    Division of Clinical Neurophysiology and Epilepsy Centre, Istituto Nazionale Neurologico C Besta, Via Celoria 11, I 20133 Milan, Italy
    Neurol Sci 25:225-9. 2004
    ....
  14. ncbi request reprint Electroencephalographic recordings of focal seizures in patients affected by periventricular nodular heterotopia: role of the heterotopic nodules in the genesis of epileptic discharges
    Giorgio Battaglia
    Division of Experimental Neurophysiology and Epileptology, Neurological Institute C Besta, Milan, Italy
    J Child Neurol 20:369-77. 2005
    ..The major role of heterotopic neurons in the genesis and propagation of epileptic discharges must be taken into account when planning surgery for epilepsy in patients with periventricular nodular heterotopia...
  15. ncbi request reprint ICTAL EEG fast activity in West syndrome: from onset to outcome
    Ferruccio Panzica
    C Besta Foundation Neurological Institute, Via Celoria 11, Milan, Italy
    Epilepsia 48:2101-10. 2007
    ..To characterize the fast EEG activities associated with infantile spasms in West syndrome, and their value in predicting the recurrence and localization of late seizures...
  16. pmc Management of the patient with medically refractory epilepsy
    Tiziana Granata
    Department of Neurology, Cleveland, OH, USA and Department of Child Neurology, Carlo Besta Neurological Institute, Milan, Italy
    Expert Rev Neurother 9:1791-802. 2009
    ..A promising approach is the use of corticosteroids that may have a dual beneficial effect. Resective brain surgery remains the ultimate and highly successful approach to multiple drug resistance in epileptic patients...
  17. ncbi request reprint Periventricular nodular heterotopia: classification, epileptic history, and genesis of epileptic discharges
    Giorgio Battaglia
    Division of Experimental Neurophysiology and Epileptology, Neurological Institute C Besta, Milan, Italy
    Epilepsia 47:86-97. 2006
    ....
  18. ncbi request reprint Antibodies against GluR3 peptides are not specific for Rasmussen's encephalitis but are also present in epilepsy patients with severe, early onset disease and intractable seizures
    Renato Mantegazza
    Immunology and Muscular Pathology Unit, Istituto Nazionale Neurologico Carlo Besta, Via Celoria 11, Milan, Italy
    J Neuroimmunol 131:179-85. 2002
    ..Antibodies against GluR3B peptide were significantly associated with frequent seizures compared to occasional or drug-controlled seizures...
  19. ncbi request reprint Epileptic and imaging findings in perinatal hypoxic-ischemic encephalopathy with ulegyria
    Flavio Villani
    Istituto Nazionale Neurologico, Via Celoria 11, Milan, Italy
    Epilepsy Res 55:235-43. 2003
    ..Drug refractoriness was an almost constant correlate of this form of symptomatic epilepsy...
  20. ncbi request reprint Intellectual and language findings and their relationship to EEG characteristics in benign childhood epilepsy with centrotemporal spikes
    Daria Riva
    Developmental Neurology Division, Istituto Nazionale Neurologico C Besta, Via Celoria 11, Milan, Italy
    Epilepsy Behav 10:278-85. 2007
    ....
  21. ncbi request reprint Similar binding to glutamate receptors by Rasmussen and partial epilepsy patients' sera
    P Bernasconi
    Immunology and Muscular Pathology Unit, Istituto Nazionale Neurologico Carlo Besta, Milan, Italy
    Neurology 59:1998-2001. 2002
    ..Histoblot analysis showed a positive staining in GluR3- and NMDA-specific regions of rat brain, providing a comprehensive CNS immunolocalization...
  22. ncbi request reprint Rasmussen's syndrome
    T Granata
    Department of Child Neurology, National Neurological Institute C Besta, Milan, Italy
    Neurol Sci 24:S239-43. 2003
    ..The use of intravenous immunoglobulins has produced encouraging results in adult-onset RE but further studies are needed to assess the effect, dosage, and schedules in childhood-onset RE...
  23. ncbi request reprint Adult-onset Rasmussen's encephalitis: anatomical-electrographic-clinical features of 7 Italian cases
    Flavio Villani
    Division of Clinical Epileptology, Istituto Nazionale Neurologico, C Besta, Milan, Italy
    Epilepsia 47:41-6. 2006
    ..The aim of this study was to verify the clinical features of A-RE, and outline a noninvasive approach that may allow its early diagnosis and treatment...
  24. ncbi request reprint Brain inflammation in epilepsy: experimental and clinical evidence
    Annamaria Vezzani
    Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Epilepsia 46:1724-43. 2005
    ..The elucidation of this aspect may open new perspectives for the pharmacologic treatment of seizures...
  25. doi request reprint Joubert syndrome with bilateral polymicrogyria: clinical and neuropathological findings in two brothers
    L Giordano
    Division of Child Neurology, Spedali Civili di Brescia, Brescia, Italy
    Am J Med Genet A 149:1511-5. 2009
    ..No mutations were detected in the AHI1 gene, the only so far associated with the JS + PMG phenotype. Moreover, linkage analysis allowed excluding all known gene loci, suggesting further genetic heterogeneity...
  26. ncbi request reprint Single-dose pharmacokinetics of lamotrigine in children: influence of age and antiepileptic comedication
    D Battino
    Carlo Besta Neurological Institute, Milan; and Clinical Pharmacology Unit, University of Pavia, Pavia, Italy
    Ther Drug Monit 23:217-22. 2001
    ..On the other hand, the lower plasma lamotrigine levels in children than in adolescents and older patients may not be explainable solely by differences in metabolic rate...
  27. ncbi request reprint The genesis of epileptogenic cerebral heterotopia: clues from experimental models
    Giorgio Battaglia
    Department of Experimental Neurophysiology, Neurological Institute C Besta, Milano, Italy
    Epileptic Disord 5:S51-8. 2003
    ..On this basis, we suggest a neurogenetic scheme for MAM-induced heterotopia that can also explain the origin and intrinsic epileptogenicity of periventricular nodular heterotopia in humans...
  28. ncbi request reprint Seizure-promoting effect of blood-brain barrier disruption
    Nicola Marchi
    Cerebrovascular Research Center, Department of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Epilepsia 48:732-42. 2007
    ..However, evidences also suggest that BBB failure may be an etiological factor contributing to the development of seizures...
  29. ncbi request reprint Familial occurrence of febrile seizures and epilepsy in severe myoclonic epilepsy of infancy (SMEI) patients with SCN1A mutations
    Maria Margherita Mancardi
    Laboratory of Neurogenetics, Unit of Muscular and Neurodegenerative Disease, Institute G Gaslini, Genova, Italy
    Epilepsia 47:1629-35. 2006
    ..We explored the genetic background of SMEI patients carrying SCN1A mutations to further shed light on the genetics of this disorder...
  30. ncbi request reprint Polymicrogyria and deletion 22q11.2 syndrome: window to the etiology of a common cortical malformation
    Nathaniel H Robin
    Department of Genetics, University of Alabama at Birmingham, USA
    Am J Med Genet A 140:2416-25. 2006
    ..Although this was not the focus of the present study, mild cerebellar anomalies are probably the most common brain malformation associated with DEL22q11...
  31. ncbi request reprint Suppressive efficacy by a commercially available blue lens on PPR in 610 photosensitive epilepsy patients
    Giuseppe Capovilla
    Epilepsy Center, Department of Child Neuropsychiatry, C Poma Hospital, Mantova, Italy
    Epilepsia 47:529-33. 2006
    ..Nonpharmacologic treatment using blue sunglasses is effective and safe in controlling photosensitivity, but large series of patients have never been studied...