Sara Castiglioni

Summary

Affiliation: Istituto di Ricerche Farmacologiche Mario Negri
Country: Italy

Publications

  1. doi request reprint Evaluation of uncertainties associated with the determination of community drug use through the measurement of sewage drug biomarkers
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Environ Sci Technol 47:1452-60. 2013
  2. doi request reprint Identification of cocaine and its metabolites in urban wastewater and comparison with the human excretion profile in urine
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    Water Res 45:5141-50. 2011
  3. doi request reprint Source, occurrence and fate of antibiotics in the Italian aquatic environment
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    J Hazard Mater 179:1042-8. 2010
  4. pmc Estimating community drug abuse by wastewater analysis
    Ettore Zuccato
    Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    Environ Health Perspect 116:1027-32. 2008
  5. doi request reprint Mass spectrometric analysis of illicit drugs in wastewater and surface water
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    Mass Spectrom Rev 27:378-94. 2008
  6. ncbi request reprint Illicit drugs, a novel group of environmental contaminants
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    Water Res 42:961-8. 2008
  7. doi request reprint Changes in illicit drug consumption patterns in 2009 detected by wastewater analysis
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via G La Masa 19, 20156 Milan, Italy
    Drug Alcohol Depend 118:464-9. 2011
  8. ncbi request reprint Pharmaceuticals in the environment in Italy: causes, occurrence, effects and control
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
    Environ Sci Pollut Res Int 13:15-21. 2006
  9. doi request reprint Illicit drugs in the environment
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    Philos Transact A Math Phys Eng Sci 367:3965-78. 2009
  10. pmc Cocaine in surface waters: a new evidence-based tool to monitor community drug abuse
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
    Environ Health 4:14. 2005

Detail Information

Publications15

  1. doi request reprint Evaluation of uncertainties associated with the determination of community drug use through the measurement of sewage drug biomarkers
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Milan, Italy
    Environ Sci Technol 47:1452-60. 2013
    ..For each step, a best practice protocol has been suggested and discussed to reduce and keep to a minimum the uncertainty of the entire procedure and to improve the reliability of the estimates of drug use...
  2. doi request reprint Identification of cocaine and its metabolites in urban wastewater and comparison with the human excretion profile in urine
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    Water Res 45:5141-50. 2011
    ..Results suggested that the measurement of other metabolites in combination with benzoylecgonine might reflect 60% of an administered dose of cocaine providing also information on different patterns of use...
  3. doi request reprint Source, occurrence and fate of antibiotics in the Italian aquatic environment
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    J Hazard Mater 179:1042-8. 2010
    ..In conclusion, antibiotics, particularly macrolides and quinolones, are widespread environmental contaminants, and urban STPs are confirmed a major source of the contamination...
  4. pmc Estimating community drug abuse by wastewater analysis
    Ettore Zuccato
    Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    Environ Health Perspect 116:1027-32. 2008
    ..The social and medical problems of drug abuse are a matter of increasing global concern. To tackle drug abuse in changing scenarios, international drug agencies need fresh methods to monitor trends and patterns of illicit drug consumption...
  5. doi request reprint Mass spectrometric analysis of illicit drugs in wastewater and surface water
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    Mass Spectrom Rev 27:378-94. 2008
    ..Instrumental conditions and fragmentation patterns of illicit drugs and their metabolites are described...
  6. ncbi request reprint Illicit drugs, a novel group of environmental contaminants
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    Water Res 42:961-8. 2008
    ..Since most of these residues still have potent pharmacological activities, their presence in the aquatic environment may have potential implications for human health and wildlife...
  7. doi request reprint Changes in illicit drug consumption patterns in 2009 detected by wastewater analysis
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via G La Masa 19, 20156 Milan, Italy
    Drug Alcohol Depend 118:464-9. 2011
    ..Wastewater analysis can provide estimates of illicit drug (ID) consumption in local communities...
  8. ncbi request reprint Pharmaceuticals in the environment in Italy: causes, occurrence, effects and control
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
    Environ Sci Pollut Res Int 13:15-21. 2006
    ..The aim of this work is to review the papers dealing with environmental contamination by pharmaceuticals in Italy, with the aim of providing a comprehensive view on a national scale...
  9. doi request reprint Illicit drugs in the environment
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
    Philos Transact A Math Phys Eng Sci 367:3965-78. 2009
    ..Given that current epidemiological methods are indirect and possibly biased, this evidence-based approach offers a new tool for estimating drug abuse in real time...
  10. pmc Cocaine in surface waters: a new evidence-based tool to monitor community drug abuse
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
    Environ Health 4:14. 2005
    ..We thus tested a more direct approach based on 'field' evidence of cocaine use by the general population...
  11. ncbi request reprint Identification of the pharmaceuticals for human use contaminating the Italian aquatic environment
    Ettore Zuccato
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Milan, Italy
    J Hazard Mater 122:205-9. 2005
    ....
  12. ncbi request reprint A multiresidue analytical method using solid-phase extraction and high-pressure liquid chromatography tandem mass spectrometry to measure pharmaceuticals of different therapeutic classes in urban wastewaters
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
    J Chromatogr A 1092:206-15. 2005
    ..The present analytical method was useful to check for pharmaceuticals in various Italian STPs and to identify the most abundant compounds...
  13. doi request reprint Novel homologs of the multiple resistance regulator marA in antibiotic-contaminated environments
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milano, Italy
    Water Res 42:4271-80. 2008
    ..Quantitative PCR assays indicate that the frequency of this gene in antropised environments seems to be related to bacterial exposure to water-borne antibiotics...
  14. ncbi request reprint Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometry
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
    Anal Chem 78:8421-9. 2006
    ..As previously reported for cocaine, this method could be useful to estimate and monitor drug consumption in the population in real time, helping social scientists and authorities to combat drug abuse...
  15. ncbi request reprint Methodological approaches for studying pharmaceuticals in the environment by comparing predicted and measured concentrations in River Po, Italy
    Sara Castiglioni
    Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
    Regul Toxicol Pharmacol 39:25-32. 2004
    ..Predictive models might therefore be useful for studying pharmaceuticals in the environment, providing enough experimental data is available on the environmental fate of the molecules...