Ilaria Capua

Summary

Affiliation: Istituto Zooprofilattico Sperimentale delle Venezie
Country: Italy

Publications

  1. ncbi The use of vaccination as an option for the control of avian influenza
    Ilaria Capua
    Office International des Epizooties and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14 A, 35020 Legnaro PD, Italy
    Avian Pathol 32:335-43. 2003
  2. ncbi Avian influenza vaccines and vaccination in birds
    Ilaria Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Vaccine 26:D70-3. 2008
  3. ncbi Avian influenza infection in birds: a challenge and opportunity for the poultry veterinarian
    I Capua
    World Organisation for Animal Health OIE, Food and Agriculture Organization of the United Nations FAO, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Padova, Italy
    Poult Sci 88:842-6. 2009
  4. ncbi Influenza A viruses grow in human pancreatic cells and cause pancreatitis and diabetes in an animal model
    Ilaria Capua
    Department of Comparative Biomedical Sciences, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    J Virol 87:597-610. 2013
  5. ncbi Avian influenza and human health
    Ilaria Capua
    National Reference Laboratory for Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14 A, 35020 Legnaro, Padua, Italy
    Acta Trop 83:1-6. 2002
  6. ncbi Increased resistance of vaccinated turkeys to experimental infection with an H7N3 low-pathogenicity avian influenza virus
    Ilaria Capua
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020, Legnaro, PD, Italy
    Avian Pathol 33:158-63. 2004
  7. ncbi Avian influenza: recent developments
    Ilaria Capua
    OIE and National Reference Laboratory for Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Avian Pathol 33:393-404. 2004
  8. ncbi Diagnosing avian influenza infection in vaccinated populations by systems for differentiating infected from vaccinated animals (DIVA)
    I Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Dev Biol (Basel) 130:137-43. 2007
  9. ncbi DIVA--a vaccination strategy enabling the detection of field exposure to avian influenza
    I Capua
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro PD, Italy
    Dev Biol (Basel) 119:229-33. 2004
  10. ncbi Ecology, epidemiology and human health implications of avian influenza viruses: why do we need to share genetic data?
    I Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Zoonoses Public Health 55:2-15. 2008

Detail Information

Publications108 found, 100 shown here

  1. ncbi The use of vaccination as an option for the control of avian influenza
    Ilaria Capua
    Office International des Epizooties and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14 A, 35020 Legnaro PD, Italy
    Avian Pathol 32:335-43. 2003
    ..It is concluded that if vaccination is accepted as an option for the control of AI, vaccine banks, including companion diagnostic tests, must be established and made available for immediate use...
  2. ncbi Avian influenza vaccines and vaccination in birds
    Ilaria Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Vaccine 26:D70-3. 2008
    ..Adequate management of a vaccination campaign, including monitoring, improved biosecurity and restriction is essential for the success of any control program for AI...
  3. ncbi Avian influenza infection in birds: a challenge and opportunity for the poultry veterinarian
    I Capua
    World Organisation for Animal Health OIE, Food and Agriculture Organization of the United Nations FAO, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Padova, Italy
    Poult Sci 88:842-6. 2009
    ..To date, control methods seem to have been unsuccessful on the larger scale, and HPAI H5N1 outbreaks continue to be reported...
  4. ncbi Influenza A viruses grow in human pancreatic cells and cause pancreatitis and diabetes in an animal model
    Ilaria Capua
    Department of Comparative Biomedical Sciences, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    J Virol 87:597-610. 2013
    ..Our findings indicate that influenza virus infection may play a role as a causative agent of pancreatitis and diabetes in humans and other mammals...
  5. ncbi Avian influenza and human health
    Ilaria Capua
    National Reference Laboratory for Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14 A, 35020 Legnaro, Padua, Italy
    Acta Trop 83:1-6. 2002
    ..Presumably this represents a very rare coincidence, but one which could result in a true influenza pandemic...
  6. ncbi Increased resistance of vaccinated turkeys to experimental infection with an H7N3 low-pathogenicity avian influenza virus
    Ilaria Capua
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020, Legnaro, PD, Italy
    Avian Pathol 33:158-63. 2004
    ....
  7. ncbi Avian influenza: recent developments
    Ilaria Capua
    OIE and National Reference Laboratory for Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Avian Pathol 33:393-404. 2004
    ....
  8. ncbi Diagnosing avian influenza infection in vaccinated populations by systems for differentiating infected from vaccinated animals (DIVA)
    I Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Dev Biol (Basel) 130:137-43. 2007
    ....
  9. ncbi DIVA--a vaccination strategy enabling the detection of field exposure to avian influenza
    I Capua
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro PD, Italy
    Dev Biol (Basel) 119:229-33. 2004
    ..1 and 95.7, respectively. The results of the present investigation suggest that the "DIVA" control strategy may represent a tool to support the eradication of avian influenza infections in poultry...
  10. ncbi Ecology, epidemiology and human health implications of avian influenza viruses: why do we need to share genetic data?
    I Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Zoonoses Public Health 55:2-15. 2008
    ..Collection and analysis of information in a transparent environment and close collaboration between the medical and veterinary scientific community are crucial to support the global AI crisis...
  11. ncbi Vaccination for notifiable avian influenza in poultry
    I Capua
    DIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padua, Italy
    Rev Sci Tech 26:217-27. 2007
    ..The availability of harmonised protocols would greatly facilitate the achievement of tangible results and would save time and avoid unnecessary wastage of resources...
  12. ncbi Animal and human health implications of avian influenza infections
    Ilaria Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Legnaro, Padova, 35020, Italy
    Biosci Rep 27:359-72. 2007
    ....
  13. ncbi The use of vaccination to combat multiple introductions of Notifiable Avian Influenza viruses of the H5 and H7 subtypes between 2000 and 2006 in Italy
    Ilaria Capua
    OIE FAO Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Vaccine 25:4987-95. 2007
    ..Transparency and sharing of field results from countries that are practising such programmes is crucial to the progressive control and ultimately the eradication of NAI infections in the animal reservoir...
  14. ncbi The challenge of avian influenza to the veterinary community
    Ilaria Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020, Legnaro, Padova, Italy
    Avian Pathol 35:189-205. 2006
    ..Only through the exchange of data, experiences, views and information will it be possible to combat this zoonosis, which represents a major threat to public health and animal well-being...
  15. ncbi Control and prevention of avian influenza in an evolving scenario
    Ilaria Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020, Legnaro, Padova, Italy
    Vaccine 25:5645-52. 2007
    ..Poultry veterinarians working for the industry or for the public sector represent the first line of defence against the pandemic threat and for the prevention and control of this infection in poultry and in wild birds...
  16. ncbi Vaccination policy applied for the control of avian influenza in Italy
    I Capua
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro PD, Italy
    Dev Biol (Basel) 114:213-9. 2003
    ....
  17. ncbi Human health implications of avian influenza viruses and paramyxoviruses
    I Capua
    Office International des Epizooties and National Reference Laboratory for Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020, Legnaro, Padova, Italy
    Eur J Clin Microbiol Infect Dis 23:1-6. 2004
    ..For this reason, any suspected case should be investigated thoroughly...
  18. ncbi Avian influenza infections in birds--a moving target
    Ilaria Capua
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Legnaro, Padua, Italy
    Influenza Other Respi Viruses 1:11-8. 2007
    ..An extraordinary effort is required to manage these epidemics from both the human and animal health perspectives...
  19. ncbi The 1999-2000 avian influenza (H7N1) epidemic in Italy: veterinary and human health implications
    Ilaria Capua
    National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14 A, 35020 Legnaro, Padova, Italy
    Acta Trop 83:7-11. 2002
    ..A reconsideration of the current definition of avian influenza adopted by the EU, could possibly be an aid to avoiding devastating epidemics for the poultry industry in Member States...
  20. ncbi Avian embryo susceptibility to Italian H7N1 avian influenza viruses belonging to different genetic lineages
    I Capua
    National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14 A, 35020 Legnaro, Italy
    Arch Virol 147:1611-21. 2002
    ..We conclude from these findings that the pathogenesis of LPAI infections in mallard embryos is different to that observed in other species, and should be investigated further...
  21. ncbi A Closer Look at the NS1 of Influenza Virus
    William G Dundon
    OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita, 10, Legnaro PD, 35020, Italy E mail
    Viruses 1:1057-72. 2009
    ..This review discusses these differences in addition to describing potential uses of NS1 in the management and control of avian influenza outbreaks...
  22. ncbi Development of a DIVA (Differentiating Infected from Vaccinated Animals) strategy using a vaccine containing a heterologous neuraminidase for the control of avian influenza
    Ilaria Capua
    National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14 A 35020 Legnaro, Italy
    Avian Pathol 32:47-55. 2003
    ..1 and 95.7, respectively. The results of the present investigation suggest that the "DIVA" control strategy may represent a tool for the control of avian influenza infections in poultry...
  23. ncbi Control of avian influenza infections in poultry with emphasis on vaccination
    Ilaria Capua
    Istituto Zooprofilattico Sperimentale delle Venezie, OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Expert Rev Anti Infect Ther 4:751-7. 2006
    ..Poultry veterinarians working for the industry or for the public sector represent the first line of defense against the pandemic threat and for the prevention and control of this infection in poultry and in wild birds...
  24. ncbi The 1999-2000 avian influenza (H7N1) epidemic in Italy
    I Capua
    National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Padua, Italy
    Vet Res Commun 27:123-7. 2003
  25. ncbi Vaccination as a tool to combat introductions of notifiable avian influenza viruses in Europe, 2000 to 2006
    I Capua
    OIE FAO Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Rev Sci Tech 28:245-59. 2009
    ..The advantages and disadvantages of vaccination need to be considered in the decision-making process, including the financial aspects of vaccination...
  26. ncbi Avian influenza--past, present and future challenges
    I Capua
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Dev Biol (Basel) 124:15-20. 2006
    ..In fact, only through the exchange of data, experiences, views and information will it be possible to combat this zoonosis that represents a major threat to public health and animal well-being...
  27. ncbi Genetic characterization of astroviruses detected in guinea fowl (Numida meleagris) reveals a distinct genotype and suggests cross-species transmission between turkey and guinea fowl
    Cristian De Battisti
    Istituto Zooprofilattico Sperimentale delle Venezie, OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, OIE Collaborating Centre for Diseases at the Human Animal Interface, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Arch Virol 157:1329-37. 2012
    ..In either case, direct or indirect interspecies transmission of astroviruses is likely to have occurred between turkey and guinea fowl, indicating the ability of viruses belonging to the family Astroviridae to cross species barriers...
  28. ncbi Evaluation of the protection induced by avian influenza vaccines containing a 1994 Mexican H5N2 LPAI seed strain against a 2008 Egyptian H5N1 HPAI virus belonging to clade 2.2.1 by means of serological and in vivo tests
    Calogero Terregino
    OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Legnaro, Padua, Italy
    Avian Pathol 39:215-22. 2010
    ..The data reported in this study also indicate that there may be a low degree of correlation between haemagglutination inhibition titres, clinical protection and reduction of shedding...
  29. ncbi Gene segment reassortment between Eurasian and American clades of avian influenza virus in Italy
    Alice Fusaro
    OIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Arch Virol 155:77-81. 2010
    ..Phylogenetic analysis of the entire genome showed that these viruses contain mixed gene segments belonging to the American and Eurasian clades...
  30. ncbi Conventional inactivated bivalent H5/H7 vaccine prevents viral localization in muscles of turkeys infected experimentally with low pathogenic avian influenza and highly pathogenic avian influenza H7N1 isolates
    Anna Toffan
    OIE, FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease, OIE Collaborating Centre for Epidemiology, Training and Control of Emerging Avian Diseases, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Avian Pathol 37:407-12. 2008
    ..In contrast, no viable virus or viral RNA could be detected in muscles of vaccinated/challenged turkeys, indicating that viral localization in muscle tissue is prevented in vaccinated birds...
  31. ncbi Genetic data from avian influenza and avian paramyxoviruses generated by the European network of excellence (EPIZONE) between 2006 and 2011--review and recommendations for surveillance
    William G Dundon
    Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Italy
    Vet Microbiol 154:209-21. 2012
    ..Based on this information and putting it all into a European context, recommendations for continued surveillance of these important viruses within Europe are presented...
  32. ncbi Introduction into Nigeria of a distinct genotype of avian influenza virus (H5N1)
    Alice Fusaro
    Molecular Biology Laboratory of the National and The World Organization for Animal Health FAO Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Emerg Infect Dis 15:445-7. 2009
    ..Phylogenetic analysis showed that the viruses are genetically closely related to European and Middle Eastern influenza A (H5N1) isolates detected in 2007...
  33. ncbi Active surveillance for avian influenza viruses in wild birds and backyard flocks in Northern Italy during 2004 to 2006
    Calogero Terregino
    OIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Avian Pathol 36:337-44. 2007
    ....
  34. ncbi Evolutionary dynamics of multiple sublineages of H5N1 influenza viruses in Nigeria from 2006 to 2008
    Alice Fusaro
    Istituto Zooprofilattico Sperimentale delle Venezie, Research and Development Department, OIE FAO, and National Reference Laboratory for Newcastle Disease and Avian Influenza, OIE Collaborating Centre for Epidemiology, Training and Control of Emerging Avian Diseases, Viale dell Universita 10, 35020, Legnaro, Padua, Italy
    J Virol 84:3239-47. 2010
    ..Our study provides new insight into the genesis and evolution of H5N1 influenza viruses in Nigeria and has important implications for targeting surveillance efforts to rapidly identify the spread of the virus into and within Nigeria...
  35. ncbi The mouse model is suitable for the study of viral factors governing transmission and pathogenesis of highly pathogenic avian influenza (HPAI) viruses in mammals
    Michela Rigoni
    OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, OIE Collaborating Centre for Diseases at the Animal Human Interface, Research and Development Department, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Vet Res 41:66. 2010
    ....
  36. ncbi Pneumo- and neurotropism of avian origin Italian highly pathogenic avian influenza H7N1 isolates in experimentally infected mice
    Michela Rigoni
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Virology 364:28-35. 2007
    ..These results suggest that HPAI viruses, other than H5N1 and H7N7, may have zoonotic implications, and support the consensus that AI infections in poultry are to be eradicated rather than contained...
  37. ncbi Development and validation of an anti-N3 indirect immunofluorescent antibody test to be used as a companion diagnostic test in the framework of a "DIVA" vaccination strategy for avian influenza infections in poultry
    Giovanni Cattoli
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Laboratorio di Virologia, Padova, Italy
    Avian Pathol 35:154-9. 2006
    ....
  38. ncbi Genetic variation of Italian avian paramyxoviruses serotype 9
    William G Dundon
    OIE, FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020, Legnaro, Padova, Italy
    Virus Genes 41:43-6. 2010
    ....
  39. ncbi A proof-of-principle study to identify suitable vaccine seed candidates to combat introductions of Eurasian lineage H5 and H7 subtype avian influenza viruses
    Maria Serena Beato
    OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, OIE Collaborating Centre for Diseases at the Human Animal Interface and for Epidemiology Training and Control of Emerging Avian Diseases, Legnaro, Padova, Italy
    Avian Pathol 39:375-82. 2010
    ..This study should be considered a starting point for a more informed approach to the selection of seed strains for the development of avian influenza vaccines against field infections caused by viruses of H5 and H7 subtypes...
  40. ncbi Unexpected heat resistance of Italian low-pathogenicity and high-pathogenicity avian influenza A viruses of H7 subtype to prolonged exposure at 37 degrees C
    Calogero Terregino
    OIE, FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease, Italy
    Avian Pathol 38:519-22. 2009
    ..In general terms, resistance was high, although some strains were more resistant than others, remaining viable after 15 days at 37 degrees C. These results should be considered when designing guidelines for outbreak management...
  41. ncbi Development and validation of a one-step real-time PCR assay for simultaneous detection of subtype H5, H7, and H9 avian influenza viruses
    Isabella Monne
    Istituto Zooprofilattico Sperimentale delle Venezie, Research and Development Department, OIE FAO, OIE Collaborating Centre for Epidemiology, Training, and Control of Emerging Avian Diseases, Legnaro, Padova, Italy
    J Clin Microbiol 46:1769-73. 2008
    ....
  42. ncbi Evidence for differing evolutionary dynamics of A/H5N1 viruses among countries applying or not applying avian influenza vaccination in poultry
    Giovanni Cattoli
    Istituto Zooprofilattico Sperimentale delle Venezie, Research and Development Department, OIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, OIE Collaborating Centre for Diseases at the Human Animal Interface, Viale dell Università 10, 35020, Legnaro, Padova, Italy
    Vaccine 29:9368-75. 2011
    ..We therefore urge a greater consideration of the potential consequences of inadequate vaccination on viral evolution...
  43. ncbi Pathogenicity of a QX strain of infectious bronchitis virus in specific pathogen free and commercial broiler chickens, and evaluation of protection induced by a vaccination programme based on the Ma5 and 4/91 serotypes
    Calogero Terregino
    OIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Legnaro PD, Italy
    Avian Pathol 37:487-93. 2008
    ..This study confirms that vaccination at 1 day old and at 14 days of age using the Ma5 and 4/91 IB vaccines may be instrumental in reducing the economic impact of QX IB virus infections in layer and broiler farms...
  44. ncbi Phylogeography and evolutionary history of reassortant H9N2 viruses with potential human health implications
    Alice Fusaro
    Istituto Zooprofilattico Sperimentale delle Venezie, Research and Development Department, OIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, OIE Collaborating Center for Diseases at the Human Animal Interface, Viale dell Universita 10, 35020 Legnaro, Padua, Italy
    J Virol 85:8413-21. 2011
    ..Our study highlights the need to constantly monitor the evolution of H9N2 viruses in poultry to better understand the potential risk to human health posed by these viruses...
  45. ncbi Co-circulation of two sublineages of HPAI H5N1 virus in the Kingdom of Saudi Arabia with unique molecular signatures suggesting separate introductions into the commercial poultry and falconry sectors
    Isabella Monne
    Istituto Zooprofilattico Sperimentale delle Venezie, OIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Viale dell Universita 10, Legnaro, Padova, Italy
    J Gen Virol 89:2691-7. 2008
    ....
  46. ncbi A conventional, inactivated oil emulsion vaccine suppresses shedding and prevents viral meat colonisation in commercial (Pekin) ducks challenged with HPAI H5N1
    Maria Serena Beato
    Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padua, Italy
    Vaccine 25:4064-72. 2007
    ..Vaccination of this species appears to be efficacious in suppressing viral shedding, and preventing viraemia and lateral spread of infection to unvaccinated and vaccinated Pekin ducks...
  47. ncbi Appearance of serum antibodies against the avian influenza nonstructural 1 protein in experimentally infected chickens and turkeys
    William G Dundon
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Italy
    Avian Dis 51:209-12. 2007
    ..This fact must be taken into consideration when using a DIVA system based on the identification of antibodies to the NS1 protein...
  48. ncbi Lyssavirus detection and typing using pyrosequencing
    Paola De Benedictis
    OIE and National Collaborating Centre for Diseases at the Animal Human Interface, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    J Clin Microbiol 49:1932-8. 2011
    ..Results from this study indicate that this procedure is suitable for lyssavirus detection in samples of both human and animal origin...
  49. ncbi Antigenic drift in H5N1 avian influenza virus in poultry is driven by mutations in major antigenic sites of the hemagglutinin molecule analogous to those for human influenza virus
    Giovanni Cattoli
    OIE FAO Reference Laboratory for avian influenza and Newcastle disease, Istituto Zooprofilattico Sperimentale delle Venezie, 35020 Legnaro PD, Italy
    J Virol 85:8718-24. 2011
    ....
  50. ncbi Control of avian influenza in poultry
    Ilaria Capua
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Emerg Infect Dis 12:1319-24. 2006
    ....
  51. ncbi Increased pathogenicity and shedding in chickens of a wild bird-origin low pathogenicity avian influenza virus of the H7N3 subtype following multiple in vivo passages in quail and turkey
    Filippo Cilloni
    AOIE FAO National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie IZSVe, Viale del Università 10, 35020 Legnaro, Padova, Italy
    Avian Dis 54:555-7. 2010
    ..This is the first time turkey has been shown to act as a species in which a virus from the wild reservoir can increase its replication activity in other domestic species...
  52. ncbi Isolation and characterization of an H10N7 avian influenza virus from poultry carcasses smuggled from China into Italy
    Maria Serena Beato
    OIE, FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Universit, Legnaro, Padova, Italy
    Avian Pathol 35:400-3. 2006
    ..Increased surveillance at borders and at a national level is recommended...
  53. ncbi Improving heat stability of haemagglutinating antigens for avian influenza
    Matteo Samuele Pizzuto
    OIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, OIE Collaborating Centre for Epidemiology, Training and Control of Emerging Avian Diseases, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita, Legnaro, Padova, Italy
    Biologicals 39:149-51. 2011
    ..Increased stability was detected both for freeze-dried antigens over an extended period of 6 months and also in heat exposed antigens that were then stored at +4C for up to 35 days post reconstitution...
  54. ncbi Genetic characterization of a new astrovirus detected in dogs suffering from diarrhoea
    Anna Toffan
    Istituto Zooprofilattico Sperimentale delle Venezie, Research and Development Department, Padova, Italy
    Vet Microbiol 139:147-52. 2009
    ..Based on the species definition for astroviruses and on the data obtained in this study, we suggest a new species of astrovirus - canine astrovirus, CaAstV - to be included in the genus Mamastrovirus...
  55. ncbi Generation of avian influenza reassortant viruses of the H7N5 subtype as potential vaccine candidates to be used in the framework of a "DIVA" vaccination strategy
    Maria Serena Beato
    OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Legnaro, 35020 Padova, Italy
    Avian Dis 51:479-80. 2007
    ..The aim of this study was to generate a prototype strain with a rare N subtype to avoid interference with the anti-N discriminatory test...
  56. ncbi Antigenic characterization of recent H5N1 highly pathogenic avian influenza viruses circulating in Egyptian poultry
    Maria Serena Beato
    OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, OIE Collaborating centre for infectious diseases at the human animal interface, Italy
    Virology 435:350-6. 2013
    ..This study highlights that the antigenic diversity of H5N1 HP Egyptian viruses may represent a potential challenge for the development of an effective vaccination programme for animal and human health in Egypt...
  57. ncbi Serological methods used for rabies post vaccination surveys: an analysis
    Paola De Benedictis
    OIE Collaborating Centre for Diseases at the Animal Human Interface, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Italy
    Vaccine 30:5611-5. 2012
    ..Our findings confirm, using a vast collection of field samples obtained during post-vaccination surveillance campaigns in Italy, the need for improved reliability of certain serological tests...
  58. ncbi Experimental infection of poults and guinea fowl with genetically distinct avian astroviruses
    Anna Toffan
    OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, OIE Collaborating Centre for Diseases at the Human Animal Interface, Istituto Zooprofilattico Sperimentale delle Venezie, 35020, Legnaro, Italy
    Avian Pathol 41:429-35. 2012
    ..Additionally, these viruses were able to infect young birds of different species causing clinical signs, thus providing experimental evidence for the infection of distinct avian astroviruses in different avian species...
  59. ncbi Molecular epidemiology and evolutionary dynamics of betanodavirus in southern Europe
    Valentina Panzarin
    Research and Innovation Department, Division of Biomedical Science, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, PD, Italy
    Infect Genet Evol 12:63-70. 2012
    ..Overall, our analyses yielded novel data on the evolutionary dynamics and phylogeography of betanodaviruses and therein provides a more complete understanding of the distribution and evolution of different genotypes in Southern Europe...
  60. ncbi Reassortant avian influenza virus (H5N1) in poultry, Nigeria, 2007
    Isabella Monne
    Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy corrected
    Emerg Infect Dis 14:637-40. 2008
    ..Our study reports an entirely different influenza virus (H5N1) reassortant becoming predominant and widespread in poultry...
  61. ncbi Avian influenza viruses in poultry products: a review
    Maria Serena Beato
    OIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico delle Venezie, PD, Italy
    Avian Pathol 38:193-200. 2009
    ..The present paper reviews existing knowledge on the presence of viable avian influenza viruses in poultry commodities...
  62. ncbi Avian embryo susceptibility to Italian H7N1 avian influenza viruses belonging to different lineages
    Franco Mutinelli
    National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14/A, 35020, Legnaro, PD) Italy
    Avian Dis 47:1145-9. 2003
    ..The findings indicate that the pathogenesis of LPAI infections in mallard embryos is different to that observed in other species and should be investigated further...
  63. ncbi Highly pathogenic avian influenza virus subtype H5N1 in Africa: a comprehensive phylogenetic analysis and molecular characterization of isolates
    Giovanni Cattoli
    OIE FAO Reference Laboratory for avian influenza and Newcastle disease, Istituto Zooprofilattico Sper le delle Venezie, Legnaro, PD, Italy
    PLoS ONE 4:e4842. 2009
    ..They further stress how imperative it is to implement sustainable control strategies to improve animal and public health at a global level...
  64. ncbi Evaluation of different serological tests for the detection of antibodies against highly pathogenic avian influenza in experimentally infected ostriches (Struthio camelus)
    Anna Toffan
    OIE, FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Avian Pathol 39:11-5. 2010
    ..The results reported herein could be of assistance to decision-makers in drafting guidelines for the definition of the health status of ostriches and for trade purposes...
  65. ncbi Progressive truncation of the Non-Structural 1 gene of H7N1 avian influenza viruses following extensive circulation in poultry
    William G Dundon
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita, 10, Legnaro 35020 PD, Italy
    Virus Res 119:171-6. 2006
    ....
  66. ncbi Inactivation of avian influenza viruses by chemical agents and physical conditions: a review
    P De Benedictis
    OIE, FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Zoonoses Public Health 54:51-68. 2007
    ..In this paper, the physical and chemical methods of inactivating AI viruses are reviewed, with particular emphasis on the practicalities of using such methods in the poultry industry...
  67. ncbi Field and laboratory findings of the first incursion of the Asian H5N1 highly pathogenic avian influenza virus in Africa
    Paola De Benedictis
    OIE, FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Padova, Legnaro, Italy
    Avian Pathol 36:115-7. 2007
    ..Clinical signs and mortality were observed in chickens, geese and ostriches. The present paper describes the clinical, pathological and virological findings of this outbreak...
  68. ncbi Influenza virus surveillance in wild birds in Italy: results of laboratory investigations in 2003-2005
    Giovanni Cattoli
    AOIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita, 10, 35020 Legnaro PD, Italy
    Avian Dis 51:414-6. 2007
    ..The isolates, belonging to 8 different avian influenza virus subtype combinations (H10N4, H1N1, H4N6, H7N7, H7N4, H5N1, H5N2, and H5N3), were obtained from migratory Anseriformes...
  69. ncbi Vaccination for avian influenza in Asia
    Ilaria Capua
    National and OIE Reference Laboratory for Avian Influenza, Viale dell'Universita 10, Legnaro, Padova35020, Italy
    Vaccine 22:4137-8. 2004
  70. ncbi A diagnostic algorithm for detection of antibodies to influenza A viruses in dogs in Italy (2006-2008)
    Paola De Benedictis
    Istituto Zooprofilattico Sperimentale delle Venezie, OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, OIE Collaborating Centre for Diseases at the Human Animal Interface, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    J Vet Diagn Invest 22:914-20. 2010
    ....
  71. ncbi Control of avian influenza in Italy: from stamping out to emergency and prophylactic vaccination
    S Marangon
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Dev Biol (Basel) 124:109-15. 2006
    ..Laboratory and field evidence indicate that vaccinated animals are more resistant to challenge and shed lower amounts of virus, thus acting as a tool for both prevention and control, thus limiting the impact of AI infections...
  72. ncbi Avian influenza in Italy 1997-2001
    I Capua
    National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14/A, 35020 Legnaro, Padova, Italy
    Avian Dis 47:839-43. 2003
    ..The description of the epidemics and the result of the control policies are reported...
  73. ncbi Field experiences in the control of avian influenza outbreaks in densely populated poultry areas
    S Marangon
    Istituto Zooprofilattico delle Venezie, Legnaro, Padova, Italy
    Dev Biol (Basel) 119:155-64. 2004
    ..The two vaccination campaigns (2000-2002 and 2002-2003) both resulted in the eradication of infection. However, the first campaign appeared to be more successful that the second and possible explanations are discussed...
  74. ncbi Development of a real-time duplex TaqMan-PCR for the detection of Equine rhinitis A and B viruses in clinical specimens
    Antonio Mori
    Istituto Zooprofilattico Sperimentale delle Venezie, Research and Development Department, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    J Virol Methods 155:175-81. 2009
    ..The assay detected ERBV in 14 of 86 nasal swabs collected from horses with respiratory disease. The real-time duplex PCR is a useful new diagnostic method for the rapid detection and differentiation of ERAV and ERBV...
  75. ncbi Practicalities of the implementation of a vaccination campaign for avian influenza
    Stefano Marangon
    Istituto Zooprofilattico delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Avian Dis 51:297-303. 2007
    ..Eventually, this will also reduce human exposure to potentially dangerous viruses...
  76. ncbi The challenge of controlling notifiable avian influenza by means of vaccination
    Ilaria Capua
    OIE FAO and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Avian Dis 51:317-22. 2007
    ..Poultry veterinarians working for the industry or for the public sector represent the first line of defense against the pandemic threat and for the prevention and control of this infection in poultry and in wild birds...
  77. ncbi Low-pathogenicity avian influenza (LPAI) in Italy (2000-01): epidemiology and control
    S Marangon
    Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 141A, 35020 Legnaro, Padova, Italy
    Avian Dis 47:1006-9. 2003
    ..The data reported in the present paper indicate that the combination of biosecurity measures, official control, and vaccination can be considered successful for the control of LPAI infections in densely populated poultry areas...
  78. ncbi Co-circulation of distinct genetic lineages of astroviruses in turkeys and guinea fowl
    G Cattoli
    Virology Department, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro PD, Italy
    Arch Virol 152:595-602. 2007
    ..This investigation provides genetic and epidemiological information contributing to a better understanding of enteric viral infections in turkeys and guinea fowl...
  79. ncbi Essential veterinary education in avian medicine: a global perspective
    I Capua
    Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Legnaro, Padua, Italy
    Rev Sci Tech 28:545-9. 2009
    ....
  80. ncbi Emergence of a new genetic lineage of Newcastle disease virus in West and Central Africa--implications for diagnosis and control
    G Cattoli
    OIE FAO Reference Laboratory for avian influenza and Newcastle disease, Istituto Zooprofilattico Sperimentale delle Venezie, Virology Department, Legnaro PD, Italy
    Vet Microbiol 142:168-76. 2010
    ..The present investigation provides important information on the epidemiology, diagnosis and control of NDV in Africa and highlights the importance of supporting surveillance in developing countries for transboundary animal diseases...
  81. ncbi Development and preliminary validation of an ad hoc N1-N3 discriminatory test for the control of avian influenza in Italy
    G Cattoli
    National Reference Laboratory for Newcastle Disease and Avian Influenza Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14/A, 35020 Legnaro, PD, Italy
    Avian Dis 47:1060-2. 2003
    ..93). It is concluded that the iIFA test is a valid tool for monitoring avian influenza infection in a vaccinated population...
  82. ncbi Use of vaccination in avian influenza control and eradication
    S Marangon
    Istituto Zooprofilattico delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Zoonoses Public Health 55:65-72. 2008
    ....
  83. ncbi Emergence of fox rabies in north-eastern Italy
    P De Benedictis
    Istituto Zooprofilattico Sperimentale delle Venezie, National Reference Centre for Rabies, Legnaro, Padova, Italy
    Euro Surveill 13:pii: 19033. 2008
    ..In October 2008, two foxes have been diagnosed with rabies in the Province of Udine, north-east Italy. One case of human exposure caused by a bite from one of the foxes has occurred and was properly treated...
  84. ncbi Molecular diagnosis of avian influenza during an outbreak
    G Cattoli
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Dev Biol (Basel) 124:99-105. 2006
    ..Based on the available information, the advantages and limits concerning the application of molecular methods during AI outbreaks are discussed in this paper...
  85. ncbi Comparison of three rapid detection systems for type A influenza virus on tracheal swabs of experimentally and naturally infected birds
    G Cattoli
    OIE and National Reference Laboratory for Newcastle Disease and Avian Influenza, Instituto Zooprofilattico delle Venezie, Legnaro PD, Italy
    Avian Pathol 33:432-7. 2004
    ..The economical and practical implications of using one of the rapid tests as an alternative to VI during an avian influenza epidemic are discussed...
  86. ncbi Clinical, gross, and microscopic findings in different avian species naturally infected during the H7N1 low- and high-pathogenicity avian influenza epidemics in Italy during 1999 and 2000
    F Mutinelli
    National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14/A, 35020 Legnaro, Italy
    Avian Dis 47:844-8. 2003
    ..In the present paper we report on the clinical, gross, histopathological, and immunohistochemical investigations performed on different avian species naturally infected by the LPAI virus and the HPAI virus...
  87. ncbi Plaque morphology of Italian H7N1 LPAI isolates in MDCK cells and in primary cells of different avian species
    G Cattoli
    National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Via Romea 14/A, 35020, Legnaro, PD) Italy
    Avian Dis 47:1161-3. 2003
    ..The presence of either AGS induced statistically significant larger plaques in cells of waterfowl origin...
  88. ncbi Conventional H5N9 vaccine suppresses shedding in specific-pathogen-free birds challenged with HPAI H5N1 A/chicken/Yamaguchi/7/2004
    C Terregino
    OIE, FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, Legnaro, 35020, Padova, Italy
    Avian Dis 51:495-7. 2007
    ....
  89. ncbi Characterization of Newcastle disease virus isolates obtained from Eurasian collared doves (Streptopelia decaocto) in Italy
    Calogero Terregino
    National Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padova, Italy
    Avian Pathol 32:63-8. 2003
    ..These findings suggest that different lineages are circulating in feral pigeon populations, and that a separate lineage affects Eurasian collared doves...
  90. ncbi Perspectives on the global threat: the challenge of avian influenza viruses for the world's veterinary community
    Ilaria Capua
    OIE FAO Reference Laboratory for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Università 10 3500 Legnaro Padova, Italy
    Avian Dis 54:176-8. 2010
    ..The veterinary community has knowledge and areas of expertise that should undoubtedly be part of strategic decisions and are essential to manage the human and animal health implications of avian influenza infections...
  91. ncbi Practical problems in controlling H5N1 high pathogenicity avian influenza at village level in Vietnam and introduction of biosecurity measures
    Alessandro Cristalli
    OIE FAO and National Reference Laboratoy for Newcastle Disease and Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita, 10, 35020 Legnaro, Padova, Italy
    Avian Dis 51:461-2. 2007
    ....
  92. ncbi Resistance of turkeys to experimental infection with an early 2009 Italian human influenza A(H1N1)v virus isolate
    C Terregino
    OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle disease, OIE Collaborating centre for infectious diseases at the human animal interface, Istituto Zooprofilattico Sperimentale delle Venezie IZSVe, Legnaro, Italy
    Euro Surveill 14:19360. 2009
    ..Our findings suggest that in its present form, the pandemic H1N1 influenza virus is not likely to be transmitted to meat turkeys and does therefore not represent an animal health or food safety issue for this species...
  93. ncbi Genetic comparison of H9N2 AI viruses isolated in Jordan in 2003
    Isabella Monne
    OIE FAO and National Reference Laboratory for Avian Influenza and Newcastle Disease Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita, 10, 35020, Legnaro, Padova, Italy
    Avian Dis 51:451-4. 2007
    ..7-98.2% homology). This homology suggests that the M gene of the Jordanian and human Hong Kong strains could derive from a common ancestor...
  94. ncbi Avian influenza in poultry in Chile
    Hernan Rojas
    Vet Rec 151:188. 2002
  95. ncbi H7N3 avian influenza in Italy
    Ilaria Capua
    Vet Rec 151:743-4. 2002
  96. ncbi Vaccination in the control of avian influenza in the EU
    Ilaria Capua
    Vet Rec 152:271. 2003
  97. ncbi Pigeon paramyxovirus isolated from a robin in Italy
    Isabella Monne
    Vet Rec 158:384. 2006
  98. ncbi Ilaria Capua profile. Italy's influenza diva
    Martin Enserink
    Science 314:918-9. 2006
  99. ncbi Avian influenza: We have the chance to make a difference
    Ilaria Capua
    Vet J 174:213-4. 2007
  100. ncbi Evidence of infection by H5N2 highly pathogenic avian influenza viruses in healthy wild waterfowl
    Nicolas Gaidet
    Centre de Cooperation Internationale en Recherche Agronomique pour le Developpement, Montpellier, France
    PLoS Pathog 4:e1000127. 2008
    ....
  101. ncbi Eradication of low pathogenicity avian influenza of the H7N3 subtype from Italy
    Ilaria Capua
    Vet Rec 154:639-40. 2004