Simone M Caccio

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. ncbi request reprint Genotyping of Giardia duodenalis from humans and dogs from Mexico using a beta-giardin nested polymerase chain reaction assay
    Marco Lalle
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Parasitol 91:203-5. 2005
  2. pmc Population-based analyses of Giardia duodenalis is consistent with the clonal assemblage structure
    Katsuhisa Takumi
    National Institute of Public Health and Environment RIVM, Laboratory for Zoonosis and Environmental Microbiology CIb LZO, P O Box 1, 3720, BA, Bilthoven, The Netherlands
    Parasit Vectors 5:168. 2012
  3. doi request reprint A rare Cryptosporidium parvum genotype associated with infection of lambs and zoonotic transmission in Italy
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Vet Parasitol 191:128-31. 2013
  4. pmc Pigs as natural hosts of Dientamoeba fragilis genotypes found in humans
    Simone M Caccio
    Istituto Superiore di Sanita, Rome, Italy
    Emerg Infect Dis 18:838-41. 2012
  5. doi request reprint Identification of Giardia species and Giardia duodenalis assemblages by sequence analysis of the 5.8S rDNA gene and internal transcribed spacers
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    Parasitology 137:919-25. 2010
  6. doi request reprint Giardia duodenalis: genetic recombination and its implications for taxonomy and molecular epidemiology
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome 00161, Italy
    Exp Parasitol 124:107-12. 2010
  7. doi request reprint Multilocus genotyping of Giardia duodenalis reveals striking differences between assemblages A and B
    S M Cacció
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Int J Parasitol 38:1523-31. 2008
  8. doi request reprint Molecular epidemiology of giardiasis
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, Italy
    Mol Biochem Parasitol 160:75-80. 2008
  9. ncbi request reprint Genetic heterogeneity at the beta-giardin locus among human and animal isolates of Giardiaduodenalis and identification of potentially zoonotic subgenotypes
    Marco Lalle
    Division of Gastroenteric and Tissue Parasitic Diseases, Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299, 00161 Rome, Italy
    Int J Parasitol 35:207-13. 2005
  10. doi request reprint The CpA135 gene as a marker to identify Cryptosporidium species infecting humans
    Fabio Tosini
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Parasitol Int 59:606-9. 2010

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Genotyping of Giardia duodenalis from humans and dogs from Mexico using a beta-giardin nested polymerase chain reaction assay
    Marco Lalle
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Parasitol 91:203-5. 2005
    ..Remarkably, cysts of assemblage B have not been found in any of the Mexican isolates studied to date...
  2. pmc Population-based analyses of Giardia duodenalis is consistent with the clonal assemblage structure
    Katsuhisa Takumi
    National Institute of Public Health and Environment RIVM, Laboratory for Zoonosis and Environmental Microbiology CIb LZO, P O Box 1, 3720, BA, Bilthoven, The Netherlands
    Parasit Vectors 5:168. 2012
    ....
  3. doi request reprint A rare Cryptosporidium parvum genotype associated with infection of lambs and zoonotic transmission in Italy
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Vet Parasitol 191:128-31. 2013
    ..Molecular typing identified the C. parvum genotype IIaA20G2R1 in the feces of the child. This is the first case of transmission of cryptosporidiosis in Italy involving lambs as source of oocysts infectious to humans...
  4. pmc Pigs as natural hosts of Dientamoeba fragilis genotypes found in humans
    Simone M Caccio
    Istituto Superiore di Sanita, Rome, Italy
    Emerg Infect Dis 18:838-41. 2012
    ..To determine whether pigs are hosts, we analyzed 152 fecal samples by microscopy and molecular methods. We confirmed that pigs are a natural host and harbor genotypes found in humans, suggesting zoonotic potential...
  5. doi request reprint Identification of Giardia species and Giardia duodenalis assemblages by sequence analysis of the 5.8S rDNA gene and internal transcribed spacers
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    Parasitology 137:919-25. 2010
    ..duodenalis assemblages can be easily distinguished. Since the major subgroups within the zoonotic assemblages A and B can be identified by sequence analysis, this assay is also informative for molecular epidemiological studies...
  6. doi request reprint Giardia duodenalis: genetic recombination and its implications for taxonomy and molecular epidemiology
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome 00161, Italy
    Exp Parasitol 124:107-12. 2010
    ..This review summarizes the experimental approaches and the results obtained, and discusses the implications of recombination from the standpoint of the taxonomy and molecular epidemiology of this widespread pathogen...
  7. doi request reprint Multilocus genotyping of Giardia duodenalis reveals striking differences between assemblages A and B
    S M Cacció
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Int J Parasitol 38:1523-31. 2008
    ..These findings raise concerns about the interpretation of genotyping data based on single markers, and indicate the need to understand the mechanisms that are responsible for the differences between G. duodenalis assemblages A and B...
  8. doi request reprint Molecular epidemiology of giardiasis
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, Italy
    Mol Biochem Parasitol 160:75-80. 2008
    ..The mechanisms that may be responsible for these findings, including allelic sequence heterozygosity and meiotic recombination, are discussed...
  9. ncbi request reprint Genetic heterogeneity at the beta-giardin locus among human and animal isolates of Giardiaduodenalis and identification of potentially zoonotic subgenotypes
    Marco Lalle
    Division of Gastroenteric and Tissue Parasitic Diseases, Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299, 00161 Rome, Italy
    Int J Parasitol 35:207-13. 2005
    ..Five of these subgenotypes, namely A1, A2, A3, A4 and B3, were found to be associated with infections of humans, of dogs and of calves; these data, therefore, supported the role of these animals as a source of infection for humans...
  10. doi request reprint The CpA135 gene as a marker to identify Cryptosporidium species infecting humans
    Fabio Tosini
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Parasitol Int 59:606-9. 2010
    ..The genetic variability was exploited to design a PCR-RFLP assay useful for a rapid identification of the most important human pathogens in the genus Cryptosporidium...
  11. pmc Giardia cysts in wastewater treatment plants in Italy
    Simone M Caccio
    Laboratory of Parasitology, Istituto Superiore di Sanita, 00161 Rome, Italy
    Appl Environ Microbiol 69:3393-8. 2003
    ..Cysts were typed as assemblage A or B, both of which are human pathogens, stressing the potential risk associated with the reuse of wastewater...
  12. pmc Genotyping of Giardia duodenalis cysts by new real-time PCR assays for detection of mixed infections in human samples
    Andre Almeida
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, 00161, Italy
    Appl Environ Microbiol 76:1895-901. 2010
    ..The assays described in this study can be used to detect Giardia cysts infectious to humans in samples from animals and in water and food...
  13. pmc Evidence of host-associated populations of Cryptosporidium parvum in Italy
    Rosanna Drumo
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    Appl Environ Microbiol 78:3523-9. 2012
    ....
  14. ncbi request reprint Unravelling Cryptosporidium and Giardia epidemiology
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Trends Parasitol 21:430-7. 2005
    ....
  15. doi request reprint High genetic polymorphism among Giardia duodenalis isolates from Sahrawi children
    Marco Lalle
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, Rome, Italy
    Trans R Soc Trop Med Hyg 103:834-8. 2009
    ..Notably, this phenomenon was not observed in sequences from assemblage A isolates. These results suggest that the genetic structure is different in isolates of assemblages A and B...
  16. ncbi request reprint Molecular identification of Cryptosporidium parvum and Giardia duodenalis in the Italian water buffalo (Bubalus bubalis)
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Vet Parasitol 150:146-9. 2007
    ..On the other hand, mozzarella cheese is probably a safe product, given that its production involves the treatment of cheese curd at 85-95 degrees C, which is likely to kill or inactivate the parasites...
  17. ncbi request reprint Molecular characterisation of Babesia canis canis and Babesia canis vogeli from naturally infected European dogs
    Simone M Caccio
    Laboratory of Parasitology, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161, Rome, Italy
    Vet Parasitol 106:285-92. 2002
    ..The new data facilitate the reliable molecular diagnosis of the subspecies of B. canis...
  18. ncbi request reprint Sequence analysis of the beta-giardin gene and development of a polymerase chain reaction-restriction fragment length polymorphism assay to genotype Giardia duodenalis cysts from human faecal samples
    Simone M Caccio
    Laboratory of Parasitology, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Int J Parasitol 32:1023-30. 2002
    ..Finally, a simple PCR-restriction fragment length polymorphism method was developed for the rapid discrimination of Assemblages and applied for the direct genetic analysis of cysts present in human faecal samples...
  19. ncbi request reprint Advances in the epidemiology, diagnosis and treatment of cryptosporidiosis
    Simone M Caccio
    Istituto Superiore di Sanita, Department of Infectious, Parasitic and Immunomediated Diseases, Viale Regina Elena, 299, 00161 Rome, Italy
    Expert Rev Anti Infect Ther 4:429-43. 2006
    ..The review concludes with a five-year outlook on some aspects of interest for future research on this pathogen...
  20. ncbi request reprint Molecular techniques to detect and identify protozoan parasites in the environment
    Simone M Caccio
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Acta Microbiol Pol 52:23-34. 2003
    ..Some application of these techniques will be illustrated with reference to two important and widespread human parasites, the apicomplexan Cryptosporidium and the flagellate Giardia...