Giovanni Broggi

..This complication was probably due to the postoperative hemodynamic changes in the vessels afferent to the AVM, associated with arterial wall dysplasia...

..The follow-up period for both cases was 1 year. Long-term bilateral high-frequency stimulation of GPI resulted in a dramatic and long-lasting improvement of neuroleptic-induced tardive dystonia...

..New therapeutical applications are expected for this functional scalpel...

..64; 0.46-0.89), but the most significant favorable prognostic factor for survival was the local delivery of mitoxantrone which reduced the risk of death to 50% (HR = 0.50; 0.38-0.68)...

..A technique for the placement of an intracavity catheter connected with a subcutaneous reservoir for further locoregional mitoxantrone administration is also described...

..A comprehensive understanding of the spatial relationships between intracranial anatomy and pathological features is a crucial element in neurosurgical planning...

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..The preoperative clinical picture, functional imaging studies, and overall clinical results in the literature are discussed...

..These findings suggest that the definition of OAs or mixed gliomas could be reshaped in agreement with the genetic information...

..We stress the concept that the combined treatments could be more effective if delivered into a smaller residual tumor mass and probably in an adjuvant setting, before tumour recurrence...

..The aim of this prospective study was to investigate the correlation between language deficits and lesion location in patients with gliomas...

..According to us, the refinement of surgical techniques and of metabolic and functional brain neuroradiological investigations will lead to a refinement of the therapeutical strategies in such patients...

..Results in contradiction with these findings, however, are present in the literature and the clinical and genetic context framing MGMT methylation is poorly characterized...

..The median follow-up was 55 months (range 12-120). 18 patients were alive without recurrence of disease. In the two patients with STGCs the death took place 16 and 35 months after diagnosis...

..The careful description of the surgical steps may contribute to a standardization of the procedure and make the interpretation of results easier even if obtained in series of patients operated on by different authors...

..The experience of different targets may be useful to guide and tailor the target choice to the individual clinical condition...

..To examine surgical findings and results of microvascular decompression (MVD) for glossopharyngeal neuralgia (GN)...

..Our data support in vivo studies suggesting a role in angiogenesis played by CXCL12, which could represent a possible prognostic factor...

..Such patients did not meet criteria for resective surgery...

..Based on the initial experiences, frameless radiosurgery appears to be an alternative treatment for Parkinsonian upper limb tremor in the presence of increased surgical risks for DBS placement...

..The balance of DBS in severe neurological disease is strongly positive even if further investigations and studies are needed to search for new applications and refine the selection criteria for the actual indications...

..The rationale, study results and selection criteria for neurostimulation procedures are also summarized, as are the disadvantages of these procedures...

..The patient was discharged neurologically intact on the 5th postembolization day. Postprocedure angiography demonstrated no ipsilateral aneurysm filling and excellent bilateral distal outflow from the left anterior cerebral artery...

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..The authors propose a novel physiopathological theory of SIH based on some anatomical considerations about the spinal venous drainage system...

..No statistically significant differences were observed between Groups 1 and 2. These findings seem to support the idea that microvascular decompression is not a dangerous surgical procedure in patients over the age of 65 years...

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..Traditional treatment options for optic nerve sheath meningiomas (ONSMs) include observation, surgery, and radiotherapy, but to date none of these has become the clear treatment of choice...

..In conclusion, CyberKnife radiosurgery appears to be both safe and effective in the treatment of skull base paragangliomas. Determining whether long-term complications will arise will require further investigation...

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..To report on a single case of arteriovenous micromalformation (micro-AVM) of the trigeminal root that was diagnosed during microvascular decompression for trigeminal neuralgia with the use of indocyanine green (ICG) videoangiography...

..65 +/- 0.27 mm (range 0.2-2.2 mm). The vertical mean error +/- SD was 0.82 +/- 0.31 mm (range 0.3-1.6 mm). CONCLUSIONS: This technique provides a simple and precise method for the evaluation of the accuracy of DBS electrode placement...

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..ABBREVIATIONS: DICOM, digital imaging and communications in medicineDTI, diffusion tensor imagingPACS, picture archiving and communication systemVR, virtual reality...

..We conclude that hemispherotomy can be performed successfully to treat medically intractable hemispheric epilepsy, providing remarkable results in terms of seizure outcome and quality of life...

..To describe a new craniotomic technique that eliminates burr holes and minimizes bone loss along the craniotomic line...

..This is the first report of a U-clip intracranial arterial microanastomosis for a high-flow extracranial-intracranial bypass using a radial artery graft...

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..To report the level of effectiveness and safety, in our experience, of CyberKnife (Accuray, Inc., Sunnyvale, CA) robotic radiosurgery as a first-line treatment against pharmacologically refractory trigeminal neuralgia...

..At present, no method exists to predict whether such sacrifice will be accommodated by the presence of collateral venous drainage. We show a simple technique to examine cerebral venous blood flow using indocyanine green videoangiography...

..8% and 17.3%, respectively. Median TTP was 21.3 and 39.5 weeks, respectively. The principal toxic effects of the regimen were: neutropenia (5 WHO grade IV), thrombocytopenia (4 WHO grade IV), nausea and vomiting...

..We here report the first Italian experience in the treatment of this pathology by means of nucleus accumbens stimulation, pointing out to some technical data which could be of help in localization of the target...

..Surgery is also recommended for symptomatic cavernomas with a satellite subacute hematoma...

..No complications or undesired side effects of electrode implant and stimulation were observed...

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..There are no persistent side effects. Hypothalamic stimulation is an effective, safe, and well-tolerated alternative to surgery for chronic patients with drug-refractory CH...

..The type of surgery should be tailored on the particular patient considering age, general physical condition, neuroradiological assessment in which MRI with dedicated sequences are mandatory, and also patient's attitude...

..We describe in detail the clinical features associated with left amygdala dysregulation induced by high-frequency stimulation through the displaced electrode...

..We propose that chronic stimulation of the IC might be an effective surgical option to motor cortex stimulation when the pain and spasticity are referred to the lower limbs...

..This approach allowed us to reduce about 30% of the number of patients treated by the anterior approach, thus consistently reducing the need for intersomatic fixation...

..We report the first patient with SUNCT in whom severe intractable pain (70 per day) was well controlled by electrode implant to and continuous stimulation of the posterior inferior hypothalamus. Ann Neurol 2005;57:925-927...

..Hypothalamic stimulation is more invasive and can be performed only in specialist neurosurgical centers. Published experience suggests that about 60% of patients with chronic CH obtain long-term benefit with hypothalamic stimulation...

..Microvascular decompression (MVD) is a non-ablative technique designed to resolve the neurovascular conflict responsible for typical idiopathic trigeminal neuralgia (TN)...

..These data point to a central pathogenesis for chronic CHs...

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..These results of this small series of patients suggest that VNS might be more suitable in patients with temporal rather than frontal or central seizure onset. Further studies are required to support this hypothesis...

..The technique of median nerve decompression at the wrist that was used for patients in Group C represents a valid alternative for treatment of CTS...

..We describe the intraoperative findings and results of an indocyanine green (ICG) video angiographic study in a patient with a developmental venous anomaly of the petrous veins...

..Magnetic resonance imaging preoperative identification of suspicious vessels along the cisternal course of the trigeminal nerve in MS patients raises the question of a possible causative role of vascular compression in MS patients...

..To evaluate the incidence and risk factors of postsurgical site infections (SSIs) in elective neurosurgical procedures in patients treated with an ultrashort antibiotic protocol...

..There is a lack of published large series to provide definitive guidelines for the surgical treatment of these complex cases. We report our 15-year experience with surgery of parasagittal meningiomas invading the SSS...