Cristina Bosetti

Summary

Affiliation: Istituto di Ricerche Farmacologiche Mario Negri
Country: Italy

Publications

  1. ncbi request reprint Aspirin and prostate cancer prevention
    Cristina Bosetti
    Department of Epidemiology, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, 20156, Milan, Italy
    Recent Results Cancer Res 202:93-100. 2014
  2. pmc The role of Mediterranean diet on the risk of pancreatic cancer
    C Bosetti
    Department of Epidemiology, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Br J Cancer 109:1360-6. 2013
  3. doi request reprint Nutrient-based dietary patterns and pancreatic cancer risk
    Cristina Bosetti
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri Milan, Italy
    Ann Epidemiol 23:124-8. 2013
  4. doi request reprint Diabetes mellitus and cancer risk in a network of case-control studies
    Cristina Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Nutr Cancer 64:643-51. 2012
  5. doi request reprint Lung cancer mortality in European women: trends and predictions
    Cristina Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, 20156 Milan, Italy
    Lung Cancer 78:171-8. 2012
  6. doi request reprint Cruciferous vegetables and cancer risk in a network of case-control studies
    C Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Ann Oncol 23:2198-203. 2012
  7. pmc Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (Panc4)
    C Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Ann Oncol 23:1880-8. 2012
  8. doi request reprint Aspirin and cancer risk: a quantitative review to 2011
    C Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche, Mario Negri, Milan, Italy
    Ann Oncol 23:1403-15. 2012
  9. ncbi request reprint The decline in breast cancer mortality in Europe: an update (to 2009)
    Cristina Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Breast 21:77-82. 2012
  10. ncbi request reprint Ambient particulate matter and preterm birth or birth weight: a review of the literature
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156, Milan, Italy
    Arch Toxicol 84:447-60. 2010

Detail Information

Publications101 found, 100 shown here

  1. ncbi request reprint Aspirin and prostate cancer prevention
    Cristina Bosetti
    Department of Epidemiology, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, 20156, Milan, Italy
    Recent Results Cancer Res 202:93-100. 2014
    ..Data on prostate cancer survival are still limited and inconsistent...
  2. pmc The role of Mediterranean diet on the risk of pancreatic cancer
    C Bosetti
    Department of Epidemiology, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Br J Cancer 109:1360-6. 2013
    ..The Mediterranean diet has been shown to have a beneficial role on various neoplasms, but data are scanty on pancreatic cancer...
  3. doi request reprint Nutrient-based dietary patterns and pancreatic cancer risk
    Cristina Bosetti
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri Milan, Italy
    Ann Epidemiol 23:124-8. 2013
    ..To add further information on dietary patterns potentially associated to pancreatic cancer, we applied an exploratory principal component factor analysis on 28 major nutrients derived from an Italian case-control study...
  4. doi request reprint Diabetes mellitus and cancer risk in a network of case-control studies
    Cristina Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Nutr Cancer 64:643-51. 2012
    ....
  5. doi request reprint Lung cancer mortality in European women: trends and predictions
    Cristina Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, 20156 Milan, Italy
    Lung Cancer 78:171-8. 2012
    ..2% per year). Although the female lung cancer epidemic in Europe is still expanding, the epidemic may be controlled through the implementation of effective anti-tobacco measures, and it will probably never reach the top US rates...
  6. doi request reprint Cruciferous vegetables and cancer risk in a network of case-control studies
    C Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Ann Oncol 23:2198-203. 2012
    ..To further understand their role, we analyzed data from a network of case-control studies conducted in Italy and Switzerland...
  7. pmc Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (Panc4)
    C Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Ann Oncol 23:1880-8. 2012
    ..To evaluate the dose-response relationship between cigarette smoking and pancreatic cancer and to examine the effects of temporal variables...
  8. doi request reprint Aspirin and cancer risk: a quantitative review to 2011
    C Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche, Mario Negri, Milan, Italy
    Ann Oncol 23:1403-15. 2012
    ..Aspirin has been associated to a reduced risk of colorectal and possibly of a few other common cancers...
  9. ncbi request reprint The decline in breast cancer mortality in Europe: an update (to 2009)
    Cristina Bosetti
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Breast 21:77-82. 2012
    ..6% at age 50-69, -5.0% at age 70-79 years). The present report confirms and further quantifies the persisting steady fall in breast cancer mortality in Europe over the last 25-30 years, which is mainly due to advancements in the therapy...
  10. ncbi request reprint Ambient particulate matter and preterm birth or birth weight: a review of the literature
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156, Milan, Italy
    Arch Toxicol 84:447-60. 2010
    ..The excess risks, if any, are small, and it is unclear whether they are causal, due to misclassification of the exposure or some sources of bias/residual confounding...
  11. doi request reprint Childhood cancer mortality in Europe, 1970-2007
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, 20156 Milan, Italy
    Eur J Cancer 46:384-94. 2010
    ..Some further improvement in childhood cancer mortality is therefore achievable through more widespread and better adoption of currently available treatments...
  12. doi request reprint Recent trends in colorectal cancer mortality in Europe
    Cristina Bosetti
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 129:180-91. 2011
    ..Interventions to further reduce colorectal cancer burden are, however, still warranted, particularly in eastern European countries...
  13. doi request reprint Trends in mortality from urologic cancers in Europe, 1970-2008
    Cristina Bosetti
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur Urol 60:1-15. 2011
    ..In recent decades, there have been substantial changes in mortality from urologic cancers in Europe...
  14. pmc High constant incidence rates of second primary cancers of the head and neck: a pooled analysis of 13 cancer registries
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 129:173-9. 2011
    ..The incidence of second HN cancers does not increase with age, but remains constant, or if anything, decreases with advancing age...
  15. ncbi request reprint Flavonoids and the risk of oral and pharyngeal cancer: a case-control study from Italy
    Marta Rossi
    Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, 20156, Milan, Italy
    Cancer Epidemiol Biomarkers Prev 16:1621-5. 2007
    ..None of the associations were significant after further allowance for vitamin C, probably on account of the high collinearity between these compounds...
  16. doi request reprint Nutrient dietary patterns and the risk of colorectal cancer: a case-control study from Italy
    Francesca Bravi
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156 Milan, Italy
    Cancer Causes Control 21:1911-8. 2010
    ..The role of diet on colorectal cancer has been considered in terms of single foods and nutrients, but less frequently in terms of dietary patterns...
  17. ncbi request reprint Flavonoids and prostate cancer risk: a study in Italy
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Nutr Cancer 56:123-7. 2006
    ..Thus, the results of the present study do not support a protective effect of flavonoids on prostate cancer in this Italian population, characterized by a high intake of flavonoid-containing foods (except isoflavone-rich foods)...
  18. ncbi request reprint Diet diversity and the risk of oral and pharyngeal cancer
    Werner Garavello
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur J Nutr 47:280-4. 2008
    ..Diet diversity has been recommended to achieve a healthy diet and prevent cancer...
  19. ncbi request reprint Intake of specific flavonoids and risk of acute myocardial infarction in Italy
    Alessandra Tavani
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, I 20157 Milan, Italy
    Public Health Nutr 9:369-74. 2006
    ....
  20. ncbi request reprint Food groups and renal cell carcinoma: a case-control study from Italy
    Francesca Bravi
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 120:681-5. 2007
    ..The results of this study provide further indications on dietary correlates of RCC, and in particular indicate that a diet rich in refined cereals and poor in vegetables may have an unfavorable role on RCC...
  21. ncbi request reprint Food groups and endometrial cancer risk: a case-control study from Italy
    Francesca Bravi
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Am J Obstet Gynecol 200:293.e1-7. 2009
    ..Although several studies have been conducted on the relation between dietary habits and endometrial cancer risk, the evidence for specific food groups is still controversial...
  22. doi request reprint Flavonoids, proanthocyanidins, and the risk of stomach cancer
    Marta Rossi
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Cancer Causes Control 21:1597-604. 2010
    ..Further adjustment for fruit and vegetables, or vitamin C, did not materially change these associations. This is the first epidemiological study to suggest that dietary proanthocyanidins have a favorable role on gastric cancer risk...
  23. ncbi request reprint Tobacco smoking, smoking cessation, and cumulative risk of upper aerodigestive tract cancers
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Am J Epidemiol 167:468-73. 2008
    ....
  24. ncbi request reprint Alcohol and tobacco use, and cancer risk for upper aerodigestive tract and liver
    Claudio Pelucchi
    Mario Negri Institute for Pharmacological Research, Milan, Italy
    Eur J Cancer Prev 17:340-4. 2008
    ..An interaction between alcohol drinking and tobacco smoking has been reported, but the issue is not adequately assessed...
  25. ncbi request reprint Flavonoids and risk of squamous cell esophageal cancer
    Marta Rossi
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 120:1560-4. 2007
    ..In conclusion, this study suggests that flavanone intake is inversely associated with esophageal cancer risk and may account, with vitamin C, for the protective effect of fruit, especially citrus fruit, on esophageal cancer...
  26. ncbi request reprint Pizza consumption and the risk of breast, ovarian and prostate cancer
    Silvano Gallus
    Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milan, Italy
    Eur J Cancer Prev 15:74-6. 2006
    ..The difference with selected studies from North America suggests that dietary and lifestyle correlates of pizza eating vary between different populations and social groups...
  27. doi request reprint Selected aspects of Mediterranean diet and cancer risk
    Claudio Pelucchi
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Nutr Cancer 61:756-66. 2009
    ....
  28. doi request reprint Macronutrients, fatty acids, cholesterol and pancreatic cancer
    Ersilia Lucenteforte
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur J Cancer 46:581-7. 2010
    ..69) and polyunsaturated fatty acids (OR=0.67). In conclusion, a diet poor in animal proteins and rich in sugars (mainly derived from fruit) appears to have a beneficial effect on pancreatic cancer risk...
  29. ncbi request reprint Citrus fruit and cancer risk in a network of case-control studies
    Roberto Foschi
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Cancer Causes Control 21:237-42. 2010
    ..Citrus fruit has shown a favorable effect against various cancers. To better understand their role in cancer risk, we analyzed data from a series of case-control studies conducted in Italy and Switzerland...
  30. ncbi request reprint Family history of cancer and the risk of prostate cancer and benign prostatic hyperplasia
    Eva Negri
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 114:648-52. 2005
    ..2, 95% CI 0.7-2.2). Our study adds further information on the association of family history of cancer and risk of PC and is, to our knowledge, the first comprehensive epidemiologic information on family history of cancer and risk of BPH...
  31. doi request reprint Dietary fiber and stomach cancer risk: a case-control study from Italy
    Francesca Bravi
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, Milan, MI 20156, Italy
    Cancer Causes Control 20:847-53. 2009
    ..Fiber intake has been inversely related to stomach cancer risk, although this issue is still controversial...
  32. ncbi request reprint Dietary glycemic index and glycemic load and risk of pancreatic cancer: a case-control study
    Marta Rossi
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Ann Epidemiol 20:460-5. 2010
    ..Carbohydrates and dietary glycemic index (GI) influence the secretion of insulin and insulin-related growth factors and may play a role in the development of diabetes and obesity, both of which have been related to pancreatic cancer risk...
  33. ncbi request reprint Food groups and risk of prostate cancer in Italy
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 110:424-8. 2004
    ....
  34. ncbi request reprint Nutritional factors, physical activity, and breast cancer by hormonal receptor status
    Valentina Rosato
    Department of Epidemiology, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156 Milan, Italy Department of Clinical Sciences and Community Health, Universita degli Studi di Milano, Milan, Italy
    Breast 22:887-93. 2013
    ..To investigate the association between food and nutrient intake, occupational and leisure-time physical activity, and body mass index and breast cancer risk by estrogen receptor (ER) and progesterone receptor (PR) status...
  35. ncbi request reprint Dietary total antioxidant capacity and colorectal cancer: a large case-control study in Italy
    Carlo La Vecchia
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
    Int J Cancer 133:1447-51. 2013
    ..The inverse association was apparently-though not significantly-stronger for rectal than for colon cancer. This is the first case-control study indicating consistent inverse relations between dietary TAC and colorectal cancer risk...
  36. ncbi request reprint Nutrient dietary patterns and the risk of breast and ovarian cancers
    Valeria Edefonti
    Istituto di Statistica Medica e Biometria Giulio A Maccacaro, Universita degli Studi di Milano, Milan, Italy
    Int J Cancer 122:609-13. 2008
    ....
  37. ncbi request reprint Intake of selected micronutrients and the risk of surgically treated benign prostatic hyperplasia: a case-control study from Italy
    Alessandra Tavani
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur Urol 50:549-54. 2006
    ..To analyze the relationship between surgically treated benign prostatic hyperplasia (BPH) and intake of selected micronutrients...
  38. ncbi request reprint Risk factors for ovarian cancer histotypes
    Francesca Chiaffarino
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea, 62, Milan, Italy
    Eur J Cancer 43:1208-13. 2007
    ..In conclusion, the association of reproductive factors and of selected dietary habits was weaker for mucinous ovarian cancer than for other histologic types...
  39. ncbi request reprint Diet diversity and the risk of laryngeal cancer: a case-control study from Italy and Switzerland
    Werner Garavello
    Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, 20156 Milan, Italy
    Oral Oncol 45:85-9. 2009
    ..The results were consistent across strata of age, alcohol drinking and tobacco smoking. This study suggests that a diet not only rich but also varied in fruit and vegetables is related to a decreased risk of laryngeal cancer risk...
  40. doi request reprint Glycemic index and glycemic load in relation to body mass index and waist to hip ratio
    Marta Rossi
    Department of Epidemiology, Mario Negri Institute for Pharmacological Research, Via La Masa, 19, 20156 Milan, Italy
    Eur J Nutr 49:459-64. 2010
    ..We therefore investigated the relation between GI and glycemic load (GL) with body mass index (BMI) and waist to hip ratio (WHR), as a measure of body fat distribution...
  41. ncbi request reprint Proanthocyanidins and the risk of colorectal cancer in Italy
    Marta Rossi
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Cancer Causes Control 21:243-50. 2010
    ..The associations were apparently stronger for rectal than for colon cancer, in the absence of significant heterogeneity. These results may explain the protective effect of vegetables and fruit on colorectal cancer...
  42. ncbi request reprint Trends in oesophageal cancer incidence and mortality in Europe
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa l9, Milan, Italy
    Int J Cancer 122:1118-29. 2008
    ..Changes in smoking habits and alcohol drinking for men, and perhaps nutrition, diet and physical activity for both sexes, can partly or largely explain these trends...
  43. ncbi request reprint Flavonoids and the risk of renal cell carcinoma
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Cancer Epidemiol Biomarkers Prev 16:98-101. 2007
    ..Allowance for vegetable and fruit consumption only partly explained these inverse relations. Thus, flavonoids, and particularly flavones and flavonols, may account, at least in part, for the favorable role of plant foods on RCC...
  44. ncbi request reprint Micronutrients and the risk of renal cell cancer: a case-control study from Italy
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 120:892-6. 2007
    ..64-1.13), 0.85 (95% CI = 0.64-1.12) for folate and 0.80 (95% CI = 0.60-1.07) for niacin. No meaningful associations emerged for lycopene (OR = 1.11). The present findings support a possible beneficial effect of vitamin E and C on RCC...
  45. ncbi request reprint Wine, beer and spirits and risk of oral and pharyngeal cancer: a case-control study from Italy and Switzerland
    Andrea Altieri
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
    Oral Oncol 40:904-9. 2004
    ....
  46. ncbi request reprint Type of alcoholic beverage and the risk of laryngeal cancer
    Werner Garavello
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur J Cancer Prev 15:69-73. 2006
    ..88 and 1.15. This study thus indicates that in the Italian population characterized by frequent wine consumption, wine is the beverage most strongly related to the risk of laryngeal cancer...
  47. ncbi request reprint Dietary iron intake and risk of non-fatal acute myocardial infarction
    Alessandra Tavani
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, I 20157 Milan, Italy
    Public Health Nutr 9:480-4. 2006
    ..This is of specific interest since iron is frequently included in supplementation and fortification of foods. We assessed the relation between dietary iron intake and the risk of non-fatal AMI...
  48. ncbi request reprint Dietary acrylamide and human cancer
    Claudio Pelucchi
    Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    Int J Cancer 118:467-71. 2006
    ..None of the trend in risk was significant. This uniquely large and comprehensive data set does not show any consistent association between intake of acrylamide and the risk of breast and several other common cancers...
  49. doi request reprint Reproductive and hormonal factors and pancreatic cancer risk in women
    Ersilia Lucenteforte
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Pancreas 40:460-3. 2011
    ..To investigate the role of menstrual, reproductive, and hormonal factors, as well as benign female conditions, on pancreatic cancer risk...
  50. ncbi request reprint Family history of cancer, its combination with smoking and drinking, and risk of squamous cell carcinoma of the esophagus
    Werner Garavello
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62 20157 Milan, Italy
    Cancer Epidemiol Biomarkers Prev 14:1390-3. 2005
    ....
  51. ncbi request reprint Influence of the Mediterranean diet on the risk of cancers of the upper aerodigestive tract
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milan, Italy
    Cancer Epidemiol Biomarkers Prev 12:1091-4. 2003
    ..This study provides evidence that an a priori defined nutritional pattern, which includes several aspects of the Mediterranean diet, favorably affects the risk of cancers of the upper aerodigestive tract...
  52. ncbi request reprint Family history of cancer and the risk of renal cell cancer
    Eva Negri
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
    Cancer Epidemiol Biomarkers Prev 15:2441-4. 2006
    ..3; 95% CI, 1.5-12.9), as suggested from previous studies. The OR of RCC was also significantly elevated for a family history of prostate cancer (OR, 1.9), leukemias (OR, 2.2), or any cancer (OR, 1.5)...
  53. ncbi request reprint Olive oil, seed oils and other added fats in relation to ovarian cancer (Italy)
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Cancer Causes Control 13:465-70. 2002
    ..This study investigates the potential role of olive oil and other added fats used for seasoning or cooking on ovarian carcinogenesis...
  54. ncbi request reprint Mediterranean diet in relation to body mass index and waist-to-hip ratio
    Marta Rossi
    Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, I 20156 Milan, Italy
    Public Health Nutr 11:214-7. 2008
    ..The Mediterranean diet is rich in fat and starch, and hence may be related to overweight. We therefore investigated the relationship between adherence to a Mediterranean diet and body mass index (BMI) and waist-to-hip ratio (WHR)...
  55. doi request reprint Flavonoids, proanthocyanidins, and cancer risk: a network of case-control studies from Italy
    Marta Rossi
    Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    Nutr Cancer 62:871-7. 2010
    ..We found inverse associations between proanthocyanidins and colorectal cancer. These associations appeared stronger for proanthocyanidins with a higher degree of polymerization (OR = 0.69 for ≥ 10 mers)...
  56. doi request reprint Food groups and alcoholic beverages and the risk of stomach cancer: a case-control study in Italy
    Ersilia Lucenteforte
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Nutr Cancer 60:577-84. 2008
    ..53, 95% CI = 0.30-0.93, P for trend = 0.08). The results of this study confirm a protective role of vegetables and fruit against stomach cancer and suggest a detrimental effect of (refined) cereals on this neoplasm...
  57. ncbi request reprint Cancer mortality in Italy, 1970-2002
    Matteo Malvezzi
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Tumori 94:640-57. 2008
    ..To update previous work on Italian cancer mortality...
  58. doi request reprint Artificial sweeteners and the risk of gastric, pancreatic, and endometrial cancers in Italy
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Cancer Epidemiol Biomarkers Prev 18:2235-8. 2009
    ....
  59. ncbi request reprint Does pizza protect against cancer?
    Silvano Gallus
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 107:283-4. 2003
    ..82 (95% CI = 0.56-1.19) for laryngeal, 0.74 (95% CI = 0.61-0.89) for colon and 0.93 (95% CI = 0.75-1.17) for rectal cancer. Pizza appears therefore to be a favorable indicator of risk for digestive tract neoplasms in this population...
  60. ncbi request reprint Retinol, carotenoids and the risk of prostate cancer: a case-control study from Italy
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 112:689-92. 2004
    ....
  61. ncbi request reprint Laryngeal cancer in women: tobacco, alcohol, nutritional, and hormonal factors
    Silvano Gallus
    Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milan, Italy
    Cancer Epidemiol Biomarkers Prev 12:514-7. 2003
    ..Alcohol and selected dietary aspects account for approximately 30% of cases, whereas menstrual and hormonal factors do not appear to have a consistent role in laryngeal carcinogenesis...
  62. ncbi request reprint Flavonoids and breast cancer risk in Italy
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62 20157 Milan, Italy
    Cancer Epidemiol Biomarkers Prev 14:805-8. 2005
    ..95), flavan-3-ols (OR, 0.86), anthocyanidins (OR, 1.09), as well as for isoflavones (OR, 1.05). The findings of this large study of an inverse association between flavones and breast cancer risk confirm the results of a Greek study...
  63. doi request reprint Diet and cancer in Mediterranean countries: carbohydrates and fats
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    Public Health Nutr 12:1595-600. 2009
    ..We considered some aspects of the Mediterranean diet (including, in particular, the consumption of olive oil and carbohydrates) on cancer risk...
  64. ncbi request reprint Macronutrients, fatty acids, cholesterol, and risk of benign prostatic hyperplasia
    Francesca Bravi
    Laboratorio di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Urology 67:1205-11. 2006
    ..Although BPH is extremely common among the elderly, its etiology-and, particularly, the role of diet and specific macronutrients-is still unclear...
  65. ncbi request reprint Flavonoids and colorectal cancer in Italy
    Marta Rossi
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Cancer Epidemiol Biomarkers Prev 15:1555-8. 2006
    ..The findings of this large study provide support for an inverse association of selected classes of flavonoids with colorectal cancer risk...
  66. ncbi request reprint Prevalence of smoking and attitude towards smoking regulation in Italy, 2004
    Silvano Gallus
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur J Cancer Prev 15:77-81. 2006
    ..To update trends in smoking prevalence in Italy to 2004, and describe the attitudes towards forthcoming regulation of smoking...
  67. ncbi request reprint Dietary intake of calcium, vitamin D, phosphorus and the risk of prostate cancer
    Alessandra Tavani
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
    Eur Urol 48:27-33. 2005
    ..A relation of prostate cancer risk with calcium, vitamin D and phosphorus has been suggested, but remains controversial...
  68. ncbi request reprint Dietary factors and oral and pharyngeal cancer risk
    Ersilia Lucenteforte
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 20156 Milan, Italy
    Oral Oncol 45:461-7. 2009
    ..In western countries, selected aspects of diet may account for 20-25% of oral and pharyngeal cancer, and the population attributable risk increases to 85-95% when tobacco and alcohol consumption are also considered...
  69. doi request reprint Trends in mortality from hepatocellular carcinoma in Europe, 1980-2004
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Hepatology 48:137-45. 2008
    ..8), and Spain (1.5) and lowest in Greece, Ireland, and Sweden (0.3). In most countries, trends at age 45-59 years were consistent with overall ones, whereas they were more favorable at age 20-44 years in both sexes...
  70. ncbi request reprint Aspirin use and pancreatic cancer risk
    Martina Bonifazi
    Istituto di Ricerche Farmacologiche Mario Negri, via Giuseppe La Masa, Milan, Italy
    Eur J Cancer Prev 19:352-4. 2010
    ..90), but the risk was based on three cases and 16 controls only. We observed no association between regular aspirin use and pancreatic cancer risk, although our results suggested a possible protective effect for long-term current users...
  71. ncbi request reprint Aspirin and risk of endometrial cancer: a case-control study from Italy
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, via Giuseppe La Masa, Milan, Italy
    Eur J Cancer Prev 19:401-3. 2010
    ..This study--the first one from a population outside North America--adds relevant information on the absence of a consistent association between aspirin use and endometrial cancer risk, even in high-risk overweight and obese women...
  72. doi request reprint Diet diversity and the risk of squamous cell esophageal cancer
    Ersilia Lucenteforte
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 123:2397-400. 2008
    ..These results add epidemiological support to the dietary guidelines recommending a more varied diet, particularly in fruit and vegetables, for esophageal cancer prevention...
  73. doi request reprint Trends in cancer mortality in Brazil, 1980-2004
    Liliane Chatenoud
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur J Cancer Prev 19:79-86. 2010
    ....
  74. doi request reprint Metabolic syndrome and pancreatic cancer risk: a case-control study in Italy and meta-analysis
    Valentina Rosato
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Metabolism 60:1372-8. 2011
    ..55 (95% CI, 1.19-2.01) for subjects with MetS. Metabolic syndrome is related to pancreatic cancer risk. Diabetes is the key component related to risk...
  75. doi request reprint Physical activity and risk of endometrial cancer: an Italian case-control study
    Alessandra Tavani
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Eur J Cancer Prev 18:303-6. 2009
    ..These findings do not support a strong relationship between physical activity and endometrial cancer risk...
  76. ncbi request reprint Channels of cigarette distribution, price and tobacco consumption in Italy
    Silvano Gallus
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Prev Med 42:132-4. 2006
    ..Limited information is available on the role of smuggling and of perceived influence of cigarette price on tobacco consumption in Italy. To elucidate the issues, we included specific questions in a survey on smoking in Italy...
  77. ncbi request reprint Cancer risk associated with alcohol and tobacco use: focus on upper aero-digestive tract and liver
    Claudio Pelucchi
    Unit of Cancer Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Alcohol Res Health 29:193-8. 2006
    ..For squamous cell carcinoma of the esophagus, alcohol and tobacco also appear to increase risk synergistically. With liver cancer, in contrast, alcohol consumption and tobaacco use appear to be independent risk factors...
  78. ncbi request reprint Influence of selected hormonal and lifestyle factors on familial propensity to ovarian cancer
    Alessandra Tavani
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Gynecol Oncol 92:922-6. 2004
    ..To study the influence of established risk factors for ovarian cancer in women with a family history of ovarian and/or breast cancer...
  79. ncbi request reprint Mortality from cutaneous malignant melanoma in Europe. Has the epidemic levelled off?
    Cristina Bosetti
    Laboratory of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Melanoma Res 14:301-9. 2004
    ..The particularly favourable trends in young people suggest that a further decline in mortality from CMM in Europe is likely to occur within the next few years...
  80. ncbi request reprint Smoking in Italy 2005-2006: effects of a comprehensive National Tobacco Regulation
    Silvano Gallus
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Prev Med 45:198-201. 2007
    ..On 10 January 2005 Italy became the first large European country adopting a comprehensive smoke-free legislation. We provide information on smoking prevalence in Italy and evaluate the effects of the 2005 regulations...
  81. ncbi request reprint Estimates of the incidence and prevalence of renal cell carcinoma in Italy in 2002 and projections for the years 2007 and 2012
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri Milan, Italy
    Tumori 95:142-5. 2009
    ..We provided estimates of the number of incident and prevalent cases of kidney and renal cell cancer in Italy overall and in various regions in 2002 and gave projections for the years 2007 and 2012...
  82. ncbi request reprint Food groups and risk of benign prostatic hyperplasia
    Francesca Bravi
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Urology 67:73-9. 2006
    ..Although BPH is an extremely common condition, particularly among older men, its risk factors, including dietary ones, remain largely undefined...
  83. ncbi request reprint Fried potatoes and human cancer
    Claudio Pelucchi
    Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
    Int J Cancer 105:558-60. 2003
    ..8-1.1. We found no evidence of interaction with age, gender, alcohol and tobacco use. Our data provide reassuring evidence for the lack of an important association between consumption of fried/baked potatoes and cancer risk...
  84. ncbi request reprint Long-term effects of oral contraceptives on ovarian cancer risk
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy
    Int J Cancer 102:262-5. 2002
    ..The present analysis indicates that, after taking into account duration of OC use, the OC protection from ovarian cancer persists for a long time after stopping use...
  85. ncbi request reprint Post-menopausal hormonal therapy and gallbladder cancer risk
    Silvano Gallus
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 99:762-3. 2002
    ..Although based on small numbers, due to the rarity of the disease, these findings provide the first direct epidemiological evidence of an association between HRT and gallbladder cancer...
  86. ncbi request reprint Diet and environmental carcinogenesis in breast/gynaecological cancers
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Curr Opin Obstet Gynecol 14:13-8. 2002
    ..Alcohol appears to be related to the risk of breast cancer and overweight is associated with post-menopausal breast cancer and is strongly related to the risk of endometrial cancer...
  87. ncbi request reprint Olive oil and cancer risk: an update of epidemiological findings through 2010
    Claudio Pelucchi
    Dipartimento di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Curr Pharm Des 17:805-12. 2011
    ..Thus, preferring olive oil to other added lipids, particularly those rich in saturated fats, can decrease the risk of upper digestive and respiratory tract neoplasms, breast and, possibly, colorectal and other cancer sites...
  88. ncbi request reprint Pipe smoking and cancers of the upper digestive tract
    Giorgia Randi
    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 121:2049-51. 2007
    ..8 (95% CI: 13.6-110.9) as compared to never smokers and light drinkers. Thus, pipe smoking and heavy alcohol drinking appears to interact at least on a multiplicative model...
  89. doi request reprint Coffee drinking and endometrial cancer risk: a metaanalysis of observational studies
    Francesca Bravi
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Am J Obstet Gynecol 200:130-5. 2009
    ..64 (95% CI, 0.48-0.86) for heavy coffee drinkers. The summary RR for an increase of 1 cup/d was 0.93 (95% CI, 0.89-0.97), which suggests an inverse relation between coffee and endometrial cancer. However, the causality must be confirmed...
  90. ncbi request reprint Benign ovarian cysts and breast cancer risk
    Cristina Bosetti
    Laboratorio di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Int J Cancer 119:1679-82. 2006
    ..Although some hormonal correlates of ovarian cysts may have a role on breast cancer risk, a biological explanation of this inverse association is still unclear...
  91. ncbi request reprint Indoor air pollution from solid fuel use, chronic lung diseases and lung cancer in Harbin, Northeast China
    Carlotta Galeone
    Istituto di Ricerche Farmacologiche Mario Negri, 19 20156 Milan, Italy
    Eur J Cancer Prev 17:473-8. 2008
    ..38-6.02) and 3.82 (95% CI: 1.97-7.41), respectively. This study gives further support and quantification of the positive association between IAP, history of selected nonmalignant lung diseases, and lung cancer risk for both the sexes...
  92. ncbi request reprint Diet and cancer risk in Mediterranean countries: open issues
    Carlo La Vecchia
    Istituto di Ricerche Farmacologiche, Mario Negri, Milano, Italy
    Public Health Nutr 9:1077-82. 2006
    ..To analyse various aspects of the Mediterranean diet in relation to the risk of several common cancers in Italy...
  93. ncbi request reprint Occupational exposure to ultraviolet radiation and risk of non-Hodgkin lymphoma
    Alessandra Tavani
    Istituto di Ricerche Farmacologiche, Mario Negri, Milan, Italy
    Eur J Cancer Prev 15:453-7. 2006
    ..Our study found no association between occupational exposure to ultraviolet radiation and the risk of non-Hodgkin lymphoma...
  94. ncbi request reprint Aspirin and cancer risk: an updated quantitative review to 2005
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157, Milan, Italy
    Cancer Causes Control 17:871-88. 2006
    ..Further, notwithstanding the large amount of epidemiological evidence, substantial uncertainties remain about the proper aspirin dose and duration of treatment...
  95. doi request reprint European studies on long-term exposure to ambient particulate matter and lung cancer
    Silvano Gallus
    Mario Negri Institute for Pharmacological Research, Milan, Italy
    Eur J Cancer Prev 17:191-4. 2008
    ..European studies of PM exposure and lung cancer do not show a clear association, but uncertainties remain for the measurement of exposure and latency...
  96. ncbi request reprint Aspirin and risk of renal cell cancer in Italy
    Alessandra Tavani
    Istituto di Ricerche Farmacologiche Mario Negri bIstituto di Statistica Medica e Biometria GA Maccacaro, Universita di Milano, Milan, Italy
    Eur J Cancer Prev 19:272-4. 2010
    ..No significant heterogeneity was found for regular use of aspirin across strata of age and sex. This study, based on a large dataset, suggests that regular use of aspirin did not increase RCC risk...
  97. ncbi request reprint Testicular cancer mortality in the Americas, 1980-2003
    Paola Bertuccio
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Cancer 109:776-9. 2007
    ..The objective of the study was to compare death rates and trends over the 1980-2003 period in all the American countries that provide data...
  98. ncbi request reprint A pooled analysis of case-control studies of thyroid cancer. VII. Cruciferous and other vegetables (International)
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Cancer Causes Control 13:765-75. 2002
    ..To investigate the association between cruciferous and other vegetables and thyroid cancer risk we systematically reanalyzed the original data from 11 case-control studies conducted in the US, Asia, and Europe...
  99. ncbi request reprint Effects of smoking cessation on the risk of laryngeal cancer: an overview of published studies
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Laboratory of Epidemiology, Via Eritrea 62, 20157 Milan, Italy
    Oral Oncol 42:866-72. 2006
    ....
  100. ncbi request reprint Coffee drinking and hepatocellular carcinoma risk: a meta-analysis
    Francesca Bravi
    Laboratorio di Epidemiologia, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Hepatology 46:430-5. 2007
    ..However, subjects with liver conditions may selectively reduce their coffee consumption...
  101. ncbi request reprint Influence of selected lifestyle factors on risk of acute myocardial infarction in subjects with familial predisposition for the disease
    Alessandra Tavani
    Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milan, Italy
    Prev Med 38:468-72. 2004
    ..The joint effect of family history of acute myocardial infarction (AMI) and selected adult life risk factors on the risk of the disease is not clear...