A Battistini

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. pmc Modulation of human immunodeficiency virus 1 replication by interferon regulatory factors
    Marco Sgarbanti
    Laboratory of Virology, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Exp Med 195:1359-70. 2002
  2. ncbi request reprint IRF regulation of HIV-1 long terminal repeat activity
    A Battistini
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Rome, Italy
    J Interferon Cytokine Res 22:27-37. 2002
  3. pmc Repression of interferon regulatory factor 1 by hepatitis C virus core protein results in inhibition of antiviral and immunomodulatory genes
    Anna R Ciccaglione
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 Rome 00161, Italy
    J Virol 81:202-14. 2007
  4. pmc Ectopic expression of interferon regulatory factor-1 potentiates granulocytic differentiation
    E M Coccia
    Laboratory of Virology, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Biochem J 360:285-94. 2001
  5. ncbi request reprint Impaired myelopoiesis in mice devoid of interferon regulatory factor 1
    U Testa
    Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanita, Rome, Italy
    Leukemia 18:1864-71. 2004
  6. ncbi request reprint IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features
    L Gabriele
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena, 299, Rome 00161, Italy
    J Leukoc Biol 80:1500-11. 2006
  7. ncbi request reprint Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-gamma and TNF-alpha in oligodendrocytes
    C Agresti
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    Eur J Neurosci 10:2975-83. 1998
  8. ncbi request reprint A full-length murine 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication
    E M Coccia
    Laboratorio di Virologia, Istituto Superiore di Sanita, Rome, Italy
    Virology 179:228-33. 1990
  9. ncbi request reprint Role of Ets-1 in transcriptional regulation of transferrin receptor and erythroid differentiation
    Giovanna Marziali
    Laboratory of Virology, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Oncogene 21:7933-44. 2002
  10. pmc Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1
    Anna L Remoli
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 Rome 00161, Italy
    Biochem J 396:371-80. 2006

Collaborators

Detail Information

Publications22

  1. pmc Modulation of human immunodeficiency virus 1 replication by interferon regulatory factors
    Marco Sgarbanti
    Laboratory of Virology, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Exp Med 195:1359-70. 2002
    ....
  2. ncbi request reprint IRF regulation of HIV-1 long terminal repeat activity
    A Battistini
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Rome, Italy
    J Interferon Cytokine Res 22:27-37. 2002
    ....
  3. pmc Repression of interferon regulatory factor 1 by hepatitis C virus core protein results in inhibition of antiviral and immunomodulatory genes
    Anna R Ciccaglione
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 Rome 00161, Italy
    J Virol 81:202-14. 2007
    ....
  4. pmc Ectopic expression of interferon regulatory factor-1 potentiates granulocytic differentiation
    E M Coccia
    Laboratory of Virology, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Biochem J 360:285-94. 2001
    ..We conclude that IRF-1 exerts a pivotal role in granulocytic differentiation and that its induction by G-CSF represents a limiting step in the early events of differentiation...
  5. ncbi request reprint Impaired myelopoiesis in mice devoid of interferon regulatory factor 1
    U Testa
    Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanita, Rome, Italy
    Leukemia 18:1864-71. 2004
    ..These results, together with the fact that IRF-1 is markedly induced early during granulo-monocytic differentiation of CD34+ cells, highlight the pivotal role of IRF-1 in the early phases of myelopoiesis...
  6. ncbi request reprint IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features
    L Gabriele
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena, 299, Rome 00161, Italy
    J Leukoc Biol 80:1500-11. 2006
    ..Together, these results indicate that IRF-1 is a key regulator of DC differentiation and maturation, exerting a variety of effects on the functional activation and tolerogenic potential of these cells...
  7. ncbi request reprint Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-gamma and TNF-alpha in oligodendrocytes
    C Agresti
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    Eur J Neurosci 10:2975-83. 1998
    ..The synergism demonstrated in the present study highlights the importance of cytokine interactions in magnifying their biological effects during brain injury and inflammation...
  8. ncbi request reprint A full-length murine 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication
    E M Coccia
    Laboratorio di Virologia, Istituto Superiore di Sanita, Rome, Italy
    Virology 179:228-33. 1990
    ..The specific resistance to EMCV can be attributed to 2-5A synthetase...
  9. ncbi request reprint Role of Ets-1 in transcriptional regulation of transferrin receptor and erythroid differentiation
    Giovanna Marziali
    Laboratory of Virology, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Oncogene 21:7933-44. 2002
    ..We conclude that Ets-1 binding activity is modulated during erythroid maturation and that a deregulated expression of this transcription factor interferes with terminal erythroid differentiation...
  10. pmc Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1
    Anna L Remoli
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 Rome 00161, Italy
    Biochem J 396:371-80. 2006
    ..These effects of Tat provide another effective mechanism by which HIV-1 affects antigen presentation in the context of the MHC class I complex and may have important implications in the use of Tat for vaccination strategies...
  11. ncbi request reprint Role of acetylases and deacetylase inhibitors in IRF-1-mediated HIV-1 long terminal repeat transcription
    Giulia Marsili
    Department of Infectious, Parasitic, and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Ann N Y Acad Sci 1030:636-43. 2004
    ....
  12. ncbi request reprint Analysis of the signal transduction pathway leading to human immunodeficiency virus-1-induced interferon regulatory factor-1 upregulation
    Marco Sgarbanti
    Department of Infectious, Parasitic, and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Ann N Y Acad Sci 1030:187-95. 2004
    ..These results suggest that in early phases of HIV-1 infection, before detectable cytokine production, NF-kappaB seems responsible for HIV-1-induced IRF-1 expression...
  13. ncbi request reprint Expression of signal transduction proteins during the differentiation of primary human erythroblasts
    Viviana Di Giacomo
    Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore Sanita, Rome, Italy
    J Cell Physiol 202:831-8. 2005
    ....
  14. ncbi request reprint Protein inhibitor of activated signal transducer and activator of transcription (STAT)-1 (PIAS-1) regulates the IFN-gamma response in macrophage cell lines
    Eliana M Coccia
    Laboratory of Immunology, Viale Regina Elena 299, 00161 Rome, Italy
    Cell Signal 14:537-45. 2002
    ..D1. Thus, our results indicate that PIAS-1 may account for the differential IFN-gamma responsiveness in macrophage cell lines at different stages of maturation...
  15. pmc Interferon regulatory factor-2 drives megakaryocytic differentiation
    Emilia Stellacci
    Laboratory of Virology, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Biochem J 377:367-78. 2004
    ..Our results provide evidence for a key role for IRF-2 in the induction of a programme of megakaryocytic differentiation, and reveal a remarkable functional diversity of this transcription factor in the regulation of cellular responses...
  16. ncbi request reprint Selective expression of type I IFN genes in human dendritic cells infected with Mycobacterium tuberculosis
    Maria Elena Remoli
    Laboratory of Immunology, Istituto Superiore di Sanita, Rome, Italy
    J Immunol 169:366-74. 2002
    ..In turn, IFN-beta-induced IRF-1 and IRF-7 may cooperate toward induction of IFN-alpha1/13 if infection persists and these factors are activated...
  17. pmc IRF-1 is required for full NF-kappaB transcriptional activity at the human immunodeficiency virus type 1 long terminal repeat enhancer
    Marco Sgarbanti
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299, Rome 00161, Italy
    J Virol 82:3632-41. 2008
    ....
  18. ncbi request reprint IRF-7: new role in the regulation of genes involved in adaptive immunity
    Marco Sgarbanti
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Ann N Y Acad Sci 1095:325-33. 2007
    ..The so far unrecognized role of IRF-7 in LMP-2 stimulation points to IRF-7 as a transcriptional regulator that bridges innate and adaptive immunity...
  19. ncbi request reprint On the role of interferon regulatory factors in HIV-1 replication
    Giulia Marsili
    Laboratory of Virology, Istituto Superiore di Sanita, Viale Regina Elena, 299, 00161 Rome, Italy
    Ann N Y Acad Sci 1010:29-42. 2003
    ....
  20. ncbi request reprint Role of Ets-1 in erythroid differentiation
    Giovanna Marziali
    Laboratory of Virology, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Blood Cells Mol Dis 29:553-61. 2002
    ..These data indicate that a decrease in Ets-1 binding activity is required for a normal erythroid maturation and that a deregulated expression of this transcription factor may interfere with terminal erythroid differentiation...
  21. ncbi request reprint Interleukin (IL)-4 inhibits phorbol-ester induced HIV-1 expression in chronically infected U1 cells independently from the autocrine effect of endogenous tumour necrosis factor-alpha, IL-1beta, and IL-1 receptor antagonist
    Delia Goletti
    Italian National Institute of Infectious Diseases Lazzaro Spallanzani, Roma, Italy
    Cytokine 17:28-35. 2002
    ..Thus, IL-4 may favour a state of microbiological quiescence in infected monocytic cells bypassing the induction of HIV expression mediated by pro-inflammatory cytokines...
  22. ncbi request reprint IFN regulatory factor-1 negatively regulates CD4+ CD25+ regulatory T cell differentiation by repressing Foxp3 expression
    Alessandra Fragale
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Immunol 181:1673-82. 2008
    ..We conclude that IRF-1 is a key negative regulator of CD4(+)CD25(+) Treg cells through direct repression of Foxp3 expression...