A Battistini

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. ncbi IRF regulation of HIV-1 long terminal repeat activity
    A Battistini
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Rome, Italy
    J Interferon Cytokine Res 22:27-37. 2002
  2. ncbi Repression of interferon regulatory factor 1 by hepatitis C virus core protein results in inhibition of antiviral and immunomodulatory genes
    Anna R Ciccaglione
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 Rome 00161, Italy
    J Virol 81:202-14. 2007
  3. ncbi IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features
    L Gabriele
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena, 299, Rome 00161, Italy
    J Leukoc Biol 80:1500-11. 2006
  4. ncbi Impaired myelopoiesis in mice devoid of interferon regulatory factor 1
    U Testa
    Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanita, Rome, Italy
    Leukemia 18:1864-71. 2004
  5. ncbi Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-gamma and TNF-alpha in oligodendrocytes
    C Agresti
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    Eur J Neurosci 10:2975-83. 1998
  6. ncbi Ectopic expression of interferon regulatory factor-1 potentiates granulocytic differentiation
    E M Coccia
    Laboratory of Virology, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Biochem J 360:285-94. 2001
  7. ncbi Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1
    Anna L Remoli
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 Rome 00161, Italy
    Biochem J 396:371-80. 2006
  8. ncbi Role of acetylases and deacetylase inhibitors in IRF-1-mediated HIV-1 long terminal repeat transcription
    Giulia Marsili
    Department of Infectious, Parasitic, and Immunomediated Diseases, Istituto Superiore di Sanit, Viale Regina Elena 299, 00161 Rome, Italy
    Ann N Y Acad Sci 1030:636-43. 2004
  9. ncbi Analysis of the signal transduction pathway leading to human immunodeficiency virus-1-induced interferon regulatory factor-1 upregulation
    Marco Sgarbanti
    Department of Infectious, Parasitic, and Immunomediated Diseases, Istituto Superiore di Sanit, Viale Regina Elena, 299-00161 Rome, Italy
    Ann N Y Acad Sci 1030:187-95. 2004
  10. ncbi Expression of signal transduction proteins during the differentiation of primary human erythroblasts
    Viviana Di Giacomo
    Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore Sanit, Rome, Italy
    J Cell Physiol 202:831-8. 2005

Collaborators

  • F Belardelli
  • J Hiscott
  • L Gabriele
  • C Agresti
  • B Ensoli
  • F Aloisi
  • Ugo Testa
  • Eliana M Coccia
  • A Kinter
  • Riccardo Gavioli
  • Benigno Valdez
  • L Cocco
  • Anna Rita Migliaccio
  • Delia Goletti
  • Marco Sgarbanti
  • Giulia Marsili
  • Emilia Stellacci
  • Edvige Perrotti
  • Anna Lisa Remoli
  • Ramona Ilari
  • Giovanna Marziali
  • Barbara Ridolfi
  • Alessandra Borsetti
  • Anna L Remoli
  • Roberto Orsatti
  • Alessandra Fragale
  • Anna R Ciccaglione
  • Viviana Di Giacomo
  • Filomena Nappi
  • Valentina Lulli
  • Maria Elena Remoli
  • Leonardo Sernicola
  • Paola Borghi
  • Angela Lanciotti
  • Massimo Venditti
  • Valentina Muto
  • Michele Equestre
  • Cinzia Marcantonio
  • Maria Rapicetta
  • Eleonora Gallerani
  • Aurelio Cafaro
  • Giovanni Migliaccio
  • Alessandro Matteucci
  • Elena Alfani
  • Silvano Capitani
  • Angela Di Baldassarre
  • Eleonora Benedetti
  • Marit Stafsnes
  • Eleonora Petrucci
  • Tiziana Feccia
  • Maria C Bellocchi
  • Graziella Orefici
  • Sandra Pellegrini
  • Elisabetta Dondi
  • Nicola Moscufo
  • Elena Giacomini
  • Simona Mazzeo
  • Georges Lutfalla

Detail Information

Publications21

  1. ncbi IRF regulation of HIV-1 long terminal repeat activity
    A Battistini
    Laboratory of Virology, Istituto Superiore di Sanita, Rome, Rome, Italy
    J Interferon Cytokine Res 22:27-37. 2002
    ....
  2. ncbi Repression of interferon regulatory factor 1 by hepatitis C virus core protein results in inhibition of antiviral and immunomodulatory genes
    Anna R Ciccaglione
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 Rome 00161, Italy
    J Virol 81:202-14. 2007
    ....
  3. ncbi IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features
    L Gabriele
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena, 299, Rome 00161, Italy
    J Leukoc Biol 80:1500-11. 2006
    ..Together, these results indicate that IRF-1 is a key regulator of DC differentiation and maturation, exerting a variety of effects on the functional activation and tolerogenic potential of these cells...
  4. ncbi Impaired myelopoiesis in mice devoid of interferon regulatory factor 1
    U Testa
    Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanita, Rome, Italy
    Leukemia 18:1864-71. 2004
    ..These results, together with the fact that IRF-1 is markedly induced early during granulo-monocytic differentiation of CD34+ cells, highlight the pivotal role of IRF-1 in the early phases of myelopoiesis...
  5. ncbi Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-gamma and TNF-alpha in oligodendrocytes
    C Agresti
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    Eur J Neurosci 10:2975-83. 1998
    ..The synergism demonstrated in the present study highlights the importance of cytokine interactions in magnifying their biological effects during brain injury and inflammation...
  6. ncbi Ectopic expression of interferon regulatory factor-1 potentiates granulocytic differentiation
    E M Coccia
    Laboratory of Virology, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Biochem J 360:285-94. 2001
    ..We conclude that IRF-1 exerts a pivotal role in granulocytic differentiation and that its induction by G-CSF represents a limiting step in the early events of differentiation...
  7. ncbi Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1
    Anna L Remoli
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 Rome 00161, Italy
    Biochem J 396:371-80. 2006
    ..These effects of Tat provide another effective mechanism by which HIV-1 affects antigen presentation in the context of the MHC class I complex and may have important implications in the use of Tat for vaccination strategies...
  8. ncbi Role of acetylases and deacetylase inhibitors in IRF-1-mediated HIV-1 long terminal repeat transcription
    Giulia Marsili
    Department of Infectious, Parasitic, and Immunomediated Diseases, Istituto Superiore di Sanit, Viale Regina Elena 299, 00161 Rome, Italy
    Ann N Y Acad Sci 1030:636-43. 2004
    ....
  9. ncbi Analysis of the signal transduction pathway leading to human immunodeficiency virus-1-induced interferon regulatory factor-1 upregulation
    Marco Sgarbanti
    Department of Infectious, Parasitic, and Immunomediated Diseases, Istituto Superiore di Sanit, Viale Regina Elena, 299-00161 Rome, Italy
    Ann N Y Acad Sci 1030:187-95. 2004
    ..These results suggest that in early phases of HIV-1 infection, before detectable cytokine production, NF-kappaB seems responsible for HIV-1-induced IRF-1 expression...
  10. ncbi Expression of signal transduction proteins during the differentiation of primary human erythroblasts
    Viviana Di Giacomo
    Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore Sanit, Rome, Italy
    J Cell Physiol 202:831-8. 2005
    ....
  11. ncbi Modulation of human immunodeficiency virus 1 replication by interferon regulatory factors
    Marco Sgarbanti
    Laboratory of Virology, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Exp Med 195:1359-70. 2002
    ....
  12. ncbi Interferon regulatory factor-2 drives megakaryocytic differentiation
    Emilia Stellacci
    Laboratory of Virology, Istituto Superiore di Sanit, Viale Regina Elena, 299-00161 Rome, Italy
    Biochem J 377:367-78. 2004
    ..Our results provide evidence for a key role for IRF-2 in the induction of a programme of megakaryocytic differentiation, and reveal a remarkable functional diversity of this transcription factor in the regulation of cellular responses...
  13. ncbi Protein inhibitor of activated signal transducer and activator of transcription (STAT)-1 (PIAS-1) regulates the IFN-gamma response in macrophage cell lines
    Eliana M Coccia
    Laboratory of Immunology, Viale Regina Elena 299, 00161 Rome, Italy
    Cell Signal 14:537-45. 2002
    ..D1. Thus, our results indicate that PIAS-1 may account for the differential IFN-gamma responsiveness in macrophage cell lines at different stages of maturation...
  14. ncbi Role of Ets-1 in transcriptional regulation of transferrin receptor and erythroid differentiation
    Giovanna Marziali
    Laboratory of Virology, Istituto Superiore di Sanit, Viale Regina Elena 299, 00161 Rome, Italy
    Oncogene 21:7933-44. 2002
    ..We conclude that Ets-1 binding activity is modulated during erythroid maturation and that a deregulated expression of this transcription factor interferes with terminal erythroid differentiation...
  15. ncbi Selective expression of type I IFN genes in human dendritic cells infected with Mycobacterium tuberculosis
    Maria Elena Remoli
    Laboratory of Immunology, Istituto Superiore di Sanit, Rome, Italy
    J Immunol 169:366-74. 2002
    ..In turn, IFN-beta-induced IRF-1 and IRF-7 may cooperate toward induction of IFN-alpha1/13 if infection persists and these factors are activated...
  16. ncbi IRF-1 is required for full NF-kappaB transcriptional activity at the human immunodeficiency virus type 1 long terminal repeat enhancer
    Marco Sgarbanti
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299, Rome 00161, Italy
    J Virol 82:3632-41. 2008
    ....
  17. ncbi IRF-7: new role in the regulation of genes involved in adaptive immunity
    Marco Sgarbanti
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Ann N Y Acad Sci 1095:325-33. 2007
    ..The so far unrecognized role of IRF-7 in LMP-2 stimulation points to IRF-7 as a transcriptional regulator that bridges innate and adaptive immunity...
  18. ncbi On the role of interferon regulatory factors in HIV-1 replication
    Giulia Marsili
    Laboratory of Virology, Istituto Superiore di Sanit, Viale Regina Elena, 299, 00161 Rome, Italy
    Ann N Y Acad Sci 1010:29-42. 2003
    ....
  19. ncbi Role of Ets-1 in erythroid differentiation
    Giovanna Marziali
    Laboratory of Virology, Istituto Superiore di Sanit, Viale Regina Elena 299, 00161 Rome, Italy
    Blood Cells Mol Dis 29:553-61. 2002
    ..These data indicate that a decrease in Ets-1 binding activity is required for a normal erythroid maturation and that a deregulated expression of this transcription factor may interfere with terminal erythroid differentiation...
  20. ncbi Interleukin (IL)-4 inhibits phorbol-ester induced HIV-1 expression in chronically infected U1 cells independently from the autocrine effect of endogenous tumour necrosis factor-alpha, IL-1beta, and IL-1 receptor antagonist
    Delia Goletti
    Italian National Institute of Infectious Diseases Lazzaro Spallanzani, Roma, Italy
    Cytokine 17:28-35. 2002
    ..Thus, IL-4 may favour a state of microbiological quiescence in infected monocytic cells bypassing the induction of HIV expression mediated by pro-inflammatory cytokines...
  21. ncbi IFN regulatory factor-1 negatively regulates CD4+ CD25+ regulatory T cell differentiation by repressing Foxp3 expression
    Alessandra Fragale
    Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Immunol 181:1673-82. 2008
    ..We conclude that IRF-1 is a key negative regulator of CD4(+)CD25(+) Treg cells through direct repression of Foxp3 expression...