D Battino

Summary

Affiliation: Istituto Nazionale Neurologico Carlo Besta
Country: Italy

Publications

  1. ncbi request reprint Trials in women
    D Battino
    The Carlo Besta Neurological Institute, Via Celoria 11, 1 20133, Milan, Italy
    Epilepsy Res 45:141-5; discussion 147. 2001
  2. ncbi request reprint Management of epilepsy during pregnancy
    Dina Battino
    Fondazione I R C C S Istituto Neurologico Carlo Besta, Milan, Italy
    Drugs 67:2727-46. 2007
  3. ncbi request reprint [Malformations in the offspring of pregnant women with epilepsy. Presentation of an international registry of antiepileptic drugs and pregnancy (EURAP)]
    D Battino
    Istituto Neurologico Carlo Besta, Milan, Italia
    Rev Neurol 34:476-80. 2002
  4. ncbi request reprint Topiramate pharmacokinetics in children and adults with epilepsy: a case-matched comparison based on therapeutic drug monitoring data
    Dina Battino
    Carlo Besta National Neurological Institute, Milan, Italy
    Clin Pharmacokinet 44:407-16. 2005
  5. ncbi request reprint Serum carbamazepine concentrations in elderly patients: a case-matched pharmacokinetic evaluation based on therapeutic drug monitoring data
    Dina Battino
    Carlo Besta National Neurological Institute, Milan, Italy
    Epilepsia 44:923-9. 2003
  6. ncbi request reprint Influence of aging on serum phenytoin concentrations: a pharmacokinetic analysis based on therapeutic drug monitoring data
    Dina Battino
    Carlo Besta National Neurological Institute, Via Celoria 11, 20133 Milan, Italy
    Epilepsy Res 59:155-65. 2004
  7. ncbi request reprint Phenobarbital pharmacokinetics in old age: a case-matched evaluation based on therapeutic drug monitoring data
    Sara Messina
    Carlo Besta National Neurological Institute, Milan, Italy
    Epilepsia 46:372-7. 2005
  8. ncbi request reprint Intrauterine growth in the offspring of epileptic women: a prospective multicenter study
    D Battino
    Carlo Besta Neurological Institute, Milan, Italy
    Epilepsy Res 36:53-60. 1999
  9. ncbi request reprint Therapeutic drug monitoring of the newer antiepileptic drugs
    Svein I Johannessen
    The National Center for Epilepsy, Sandvika, Norway, Carlo Besta, Milan, Italy
    Ther Drug Monit 25:347-63. 2003
  10. ncbi request reprint Assessment of teratogenic risk
    D Battino
    Neurological Institute Carlo Besta, Via Celoria 11, 1 20133, Milan, Italy
    Epilepsy Res 45:171-3; discussion 175-6. 2001

Detail Information

Publications18

  1. ncbi request reprint Trials in women
    D Battino
    The Carlo Besta Neurological Institute, Via Celoria 11, 1 20133, Milan, Italy
    Epilepsy Res 45:141-5; discussion 147. 2001
    ..These considerations become even more critical when pregnant and lactating women are considered, since any risk for the offspring is unacceptable unless drug administration is likely to have major medical benefits for the mother...
  2. ncbi request reprint Management of epilepsy during pregnancy
    Dina Battino
    Fondazione I R C C S Istituto Neurologico Carlo Besta, Milan, Italy
    Drugs 67:2727-46. 2007
    ..Any major change in the treatment of a woman with epilepsy should ideally be completed before conception. Regular monitoring of drug concentrations is recommended during pregnancy, in particular for lamotrigine and oxcarbazepine...
  3. ncbi request reprint [Malformations in the offspring of pregnant women with epilepsy. Presentation of an international registry of antiepileptic drugs and pregnancy (EURAP)]
    D Battino
    Istituto Neurologico Carlo Besta, Milan, Italia
    Rev Neurol 34:476-80. 2002
    ..Wide participation from interested physicians is essential for the achievement of the study objectives, which are expected to lead to important advances in pre pregnancy counselling and overall clinical management of women with epilepsy...
  4. ncbi request reprint Topiramate pharmacokinetics in children and adults with epilepsy: a case-matched comparison based on therapeutic drug monitoring data
    Dina Battino
    Carlo Besta National Neurological Institute, Milan, Italy
    Clin Pharmacokinet 44:407-16. 2005
    ..To compare the steady-state pharmacokinetics of topiramate in a large population of children and adults with epilepsy in a therapeutic drug monitoring setting...
  5. ncbi request reprint Serum carbamazepine concentrations in elderly patients: a case-matched pharmacokinetic evaluation based on therapeutic drug monitoring data
    Dina Battino
    Carlo Besta National Neurological Institute, Milan, Italy
    Epilepsia 44:923-9. 2003
    ..To assess the influence of aging on the steady-state pharmacokinetics of carbamazepine (CBZ) in a large population of patients evaluated in a therapeutic drug monitoring (TDM) setting...
  6. ncbi request reprint Influence of aging on serum phenytoin concentrations: a pharmacokinetic analysis based on therapeutic drug monitoring data
    Dina Battino
    Carlo Besta National Neurological Institute, Via Celoria 11, 20133 Milan, Italy
    Epilepsy Res 59:155-65. 2004
    ..Interpretation of the latter, however, should take into account the possibility of an increase in the fraction of unbound drug...
  7. ncbi request reprint Phenobarbital pharmacokinetics in old age: a case-matched evaluation based on therapeutic drug monitoring data
    Sara Messina
    Carlo Besta National Neurological Institute, Milan, Italy
    Epilepsia 46:372-7. 2005
    ..To assess the influence of aging on the pharmacokinetics of phenobarbital (PB) at steady state in patients receiving long-term therapy...
  8. ncbi request reprint Intrauterine growth in the offspring of epileptic women: a prospective multicenter study
    D Battino
    Carlo Besta Neurological Institute, Milan, Italy
    Epilepsy Res 36:53-60. 1999
    ....
  9. ncbi request reprint Therapeutic drug monitoring of the newer antiepileptic drugs
    Svein I Johannessen
    The National Center for Epilepsy, Sandvika, Norway, Carlo Besta, Milan, Italy
    Ther Drug Monit 25:347-63. 2003
    ..Although routine monitoring in general cannot be recommended at present, measurements of some of the drugs is undoubtedly of help with individualization of treatment in selected cases in a particular clinical setting...
  10. ncbi request reprint Assessment of teratogenic risk
    D Battino
    Neurological Institute Carlo Besta, Via Celoria 11, 1 20133, Milan, Italy
    Epilepsy Res 45:171-3; discussion 175-6. 2001
    ..Further requisites are a clear definition of congenital malformation and prolonged follow-up to detect the occurrence of congenital malformations not detected at birth...
  11. ncbi request reprint EURAP: an international registry of antiepileptic drugs and pregnancy
    Torbjorn Tomson
    Epilepsia 45:1463-4. 2004
  12. ncbi request reprint Teratogenic effects of antiepileptic drugs
    Torbjorn Tomson
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Seizure 17:166-71. 2008
    ..Retrospective and a few small prospective studies suggest that exposure to valproate also might be associated with a lower verbal IQ at school age, but further prospective studies are needed to draw firm conclusions...
  13. ncbi request reprint Antiepileptic drug exposure and major congenital malformations: the role of pregnancy registries
    Torbjorn Tomson
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Epilepsy Behav 11:277-82. 2007
    ..This review provides a critical discussion and comparison of important methodological aspects of AED and pregnancy registries along with a summary of results published so far...
  14. doi request reprint Pregnancy registries in epilepsy: a consensus statement on health outcomes
    K J Meador
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Neurology 71:1109-17. 2008
    ..There is a critical need for investigations to delineate the underlying mechanisms and explain the variance seen in outcomes across AEDs and within a single AED...
  15. ncbi request reprint The influence of old age and enzyme inducing comedication on the pharmacokinetics of valproic acid at steady-state: A case-matched evaluation based on therapeutic drug monitoring data
    Cinzia Fattore
    Clinical Pharmacology Unit, University of Pavia, Piazza Botta 10, Pavia, Italy
    Epilepsy Res 70:153-60. 2006
    ..To evaluate the influence of aging on the pharmacokinetics of valproic acid (VPA) at steady-state and on the susceptibility of VPA metabolism to enzyme induction by antiepileptic comedication...
  16. ncbi request reprint Teratogenicity of antiepileptic drugs: state of the art
    Torbjorn Tomson
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Curr Opin Neurol 18:135-40. 2005
    ..This reviews addresses recent reports on the risk for birth defects and impaired postnatal development attributable to prenatal exposure to AEDs...
  17. ncbi request reprint Navigating toward fetal and maternal health: the challenge of treating epilepsy in pregnancy
    Torbjorn Tomson
    Department of Neurology, Karolinska Hospital, Stockholm, Sweden torbjorn tomson kus se
    Epilepsia 45:1171-5. 2004
    ....
  18. ncbi request reprint Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium
    Torbjorn Tomson
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Clin Pharmacokinet 46:209-19. 2007
    ..Systematic studies of the effects of pregnancy on the pharmacokinetics of the other newer-generation AEDs are urgently needed...