C M Ausiello

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. ncbi request reprint 60-kDa heat shock protein of Chlamydia pneumoniae is a target of T-cell immune response
    C M Ausiello
    Unit of Anti Infectious Immunity, Department of Infectious, Parasitic, and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Biol Regul Homeost Agents 19:136-40. 2005
  2. ncbi request reprint Soluble CD30 and lymphocyte activation gene-3 (CD223), as potential serological markers of T helper-type cytokine response induced by acellular pertussis vaccine
    C M Ausiello
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Int J Immunopathol Pharmacol 19:97-104. 2006
  3. ncbi request reprint 60-kDa heat shock protein of Chlamydia pneumoniae promotes a T helper type 1 immune response through IL-12/IL-23 production in monocyte-derived dendritic cells
    Clara Maria Ausiello
    Department of Infectious, Parasitic, and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Microbes Infect 8:714-20. 2006
  4. ncbi request reprint Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells
    Clara Maria Ausiello
    Department of Infectious, Parasitic and Immune Mediated Diseases, Anti infectious Immunity Unit, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Microbes Infect 8:2640-6. 2006
  5. pmc T-cell immune response assessment as a complement to serology and intranasal protection assays in determining the protective immunity induced by acellular pertussis vaccines in mice
    C M Ausiello
    Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, 00161 Rome, Italy
    Clin Diagn Lab Immunol 10:637-42. 2003
  6. ncbi request reprint Native and genetically inactivated pertussis toxins induce human dendritic cell maturation and synergize with lipopolysaccharide in promoting T helper type 1 responses
    Clara M Ausiello
    Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, Rome 00161, Italy
    J Infect Dis 186:351-60. 2002
  7. pmc Cell-mediated immune responses in four-year-old children after primary immunization with acellular pertussis vaccines
    C M Ausiello
    Departments of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, 00161 Rome, Italy
    Infect Immun 67:4064-71. 1999
  8. ncbi request reprint Cell-mediated immune response of healthy adults to Bordetella pertussis vaccine antigens
    C M Ausiello
    Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, Rome, Italy
    J Infect Dis 178:466-70. 1998
  9. ncbi request reprint Cell-mediated immunity and antibody responses to Bordetella pertussis antigens in children with a history of pertussis infection and in recipients of an acellular pertussis vaccine
    C M Ausiello
    Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Infect Dis 181:1989-95. 2000
  10. ncbi request reprint Interaction between human interleukin-2-activated natural killer cells and heat-killed germ tube forms of Candida albicans
    G Arancia
    Laboratory of Ultrastructures, Istituto Superiore di Sanita, Rome, Italy
    Cell Immunol 186:28-38. 1998

Detail Information

Publications16

  1. ncbi request reprint 60-kDa heat shock protein of Chlamydia pneumoniae is a target of T-cell immune response
    C M Ausiello
    Unit of Anti Infectious Immunity, Department of Infectious, Parasitic, and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Biol Regul Homeost Agents 19:136-40. 2005
    ..Thus the evaluation of specific HSP60 CMI response in healthy subject could be useful to monitor the reactivity to Chlamydia pneumoniae possibly providing a link to CHD pathologies...
  2. ncbi request reprint Soluble CD30 and lymphocyte activation gene-3 (CD223), as potential serological markers of T helper-type cytokine response induced by acellular pertussis vaccine
    C M Ausiello
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Int J Immunopathol Pharmacol 19:97-104. 2006
    ..Overall, sCD30 and sCD223 levels seem to be promising candidate markers to assess the induction of Th-type responses in vaccine recipients...
  3. ncbi request reprint 60-kDa heat shock protein of Chlamydia pneumoniae promotes a T helper type 1 immune response through IL-12/IL-23 production in monocyte-derived dendritic cells
    Clara Maria Ausiello
    Department of Infectious, Parasitic, and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Microbes Infect 8:714-20. 2006
    ..Our data suggest that Cp-HSP60-matured DC may contribute to T-cell mediated immunopathology of atherosclerosis via a chronic stimulation of Th1 immune responses...
  4. ncbi request reprint Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells
    Clara Maria Ausiello
    Department of Infectious, Parasitic and Immune Mediated Diseases, Anti infectious Immunity Unit, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Microbes Infect 8:2640-6. 2006
    ..These data are of interest also in the light of the possible use of SLPs in a multicomponent vaccine against C. difficile infections for high-risk patients...
  5. pmc T-cell immune response assessment as a complement to serology and intranasal protection assays in determining the protective immunity induced by acellular pertussis vaccines in mice
    C M Ausiello
    Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, 00161 Rome, Italy
    Clin Diagn Lab Immunol 10:637-42. 2003
    ....
  6. ncbi request reprint Native and genetically inactivated pertussis toxins induce human dendritic cell maturation and synergize with lipopolysaccharide in promoting T helper type 1 responses
    Clara M Ausiello
    Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, Rome 00161, Italy
    J Infect Dis 186:351-60. 2002
    ..The synergic interaction between PT and LPS in IL-12 production might be relevant for the mechanisms of vaccine-induced protection...
  7. pmc Cell-mediated immune responses in four-year-old children after primary immunization with acellular pertussis vaccines
    C M Ausiello
    Departments of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, 00161 Rome, Italy
    Infect Immun 67:4064-71. 1999
    ..pertussis. This might explain, at least in part, the persistence of protection against typical pertussis in aP vaccine recipients despite a substantial waning of both Ab and CMI responses induced by the primary immunization...
  8. ncbi request reprint Cell-mediated immune response of healthy adults to Bordetella pertussis vaccine antigens
    C M Ausiello
    Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, Rome, Italy
    J Infect Dis 178:466-70. 1998
    ..The data suggest that most healthy adults are repeatedly exposed to B. pertussis, with natural acquisition of antigen-specific CMI and a putatively protective type 1 cytokine pattern...
  9. ncbi request reprint Cell-mediated immunity and antibody responses to Bordetella pertussis antigens in children with a history of pertussis infection and in recipients of an acellular pertussis vaccine
    C M Ausiello
    Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Infect Dis 181:1989-95. 2000
    ..Thus, years after disease or vaccination, CMI response to PT or circulating PT antibodies appears to be the main distinctive feature of pertussis-protected DTaP recipients or pertussis-affected DT recipients...
  10. ncbi request reprint Interaction between human interleukin-2-activated natural killer cells and heat-killed germ tube forms of Candida albicans
    G Arancia
    Laboratory of Ultrastructures, Istituto Superiore di Sanita, Rome, Italy
    Cell Immunol 186:28-38. 1998
    ..The ultimate results are the programmed death of LAK cells and the enhancement of the fungicidal activity exerted by competent cells...
  11. ncbi request reprint Cell mediated cytotoxicity and cytokine production in peripheral blood mononuclear cells of glioma patients
    C M Ausiello
    Istituto CNR Tipizzazione Tissutale e Problemi della Dialisi, , Rome, Italy
    Eur J Cancer 27:646-50. 1991
    ..They also provide indirect support for a possible clinical use of IFN-gamma as an immunopotentiating agent in gliomatous subjects...
  12. ncbi request reprint Lipooligosaccharide from Bordetella pertussis induces mature human monocyte-derived dendritic cells and drives a Th2 biased response
    Giorgio Fedele
    Department of Infectious, Parasitic and Immune Mediated Diseases, Anti infectious Immunity Unit, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Microbes Infect 9:855-63. 2007
    ..Considering these properties, the use of LOS in the formulation of acellular pertussis vaccines to potentiate protective and adjuvant capacity should be taken into consideration...
  13. pmc Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction
    Fabiana Spensieri
    Istituto Superiore di Sanita, Department of Infectious, Parasitic, and Immune Mediated Diseases, Rome, Italy
    Infect Immun 74:2831-8. 2006
    ..The present study suggests that ACT-dependent cAMP induction leads to the inhibition of pathways ultimately leading to IL-12 p35 production, thus representing a mechanism for B. pertussis to escape the host immune response...
  14. ncbi request reprint CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells
    Loredana Frasca
    Department of Infectious, Parasitic, and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    Blood 107:2392-9. 2006
    ..These findings may lay out the basis to assess the functional role(s) of human CD38 in infections, autoimmune diseases, and neoplastic disorders...
  15. ncbi request reprint CD38 is expressed on human mature monocyte-derived dendritic cells and is functionally involved in CD83 expression and IL-12 induction
    Giorgio Fedele
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    Eur J Immunol 34:1342-50. 2004
    ..Activation via agonistic anti-CD38 mAb induces up-regulation of CD83 expression and IL-12 secretion, whereas disruption of CD38/CD31 interaction inhibits CD83 expression, IL-12 secretion and MDDC-induced allogeneic T cell proliferation...
  16. ncbi request reprint IFN-gamma arms human dendritic cells to perform multiple effector functions
    Loredana Frasca
    Department of Infectious, Parasitic, and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Immunol 180:1471-81. 2008
    ..These data also help understand the dual role exerted by this cytokine as both an inducer and a regulator of inflammation and immune response...