F Aloisi

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. pmc Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain
    Barbara Serafini
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Exp Med 204:2899-912. 2007
  2. ncbi request reprint Lymphoid neogenesis in chronic inflammatory diseases
    Francesca Aloisi
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Rome, Italy
    Nat Rev Immunol 6:205-17. 2006
  3. ncbi request reprint Intracerebral regulation of immune responses
    F Aloisi
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    Ann Med 33:510-5. 2001
  4. ncbi request reprint Immune function of microglia
    F Aloisi
    Neurophysiology Unit, Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Roma, Italy
    Glia 36:165-79. 2001
  5. ncbi request reprint Glia-T cell dialogue
    F Aloisi
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Roma, Italy
    J Neuroimmunol 107:111-7. 2000
  6. ncbi request reprint Relative efficiency of microglia, astrocytes, dendritic cells and B cells in naive CD4+ T cell priming and Th1/Th2 cell restimulation
    F Aloisi
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Roma, Italy
    Eur J Immunol 29:2705-14. 1999
  7. doi request reprint Lymphoid chemokines in chronic neuroinflammation
    Francesca Aloisi
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Neuroimmunol 198:106-12. 2008
  8. ncbi request reprint Opposite effects of interferon-gamma and prostaglandin E2 on tumor necrosis factor and interleukin-10 production in microglia: a regulatory loop controlling microglia pro- and anti-inflammatory activities
    F Aloisi
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Roma, Italy
    J Neurosci Res 56:571-80. 1999
  9. ncbi request reprint ATP regulates oligodendrocyte progenitor migration, proliferation, and differentiation: involvement of metabotropic P2 receptors
    C Agresti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Roma, Italy
    Brain Res Brain Res Rev 48:157-65. 2005
  10. ncbi request reprint Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-gamma and TNF-alpha in oligodendrocytes
    C Agresti
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    Eur J Neurosci 10:2975-83. 1998

Collaborators

Detail Information

Publications16

  1. pmc Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain
    Barbara Serafini
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Exp Med 204:2899-912. 2007
    ....
  2. ncbi request reprint Lymphoid neogenesis in chronic inflammatory diseases
    Francesca Aloisi
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Rome, Italy
    Nat Rev Immunol 6:205-17. 2006
    ..As more information on these issues becomes available, a better understanding of the role of lymphoid neogenesis in promoting chronic inflammation might eventually lead to new strategies to target immunopathological processes...
  3. ncbi request reprint Intracerebral regulation of immune responses
    F Aloisi
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    Ann Med 33:510-5. 2001
    ..In this article we shall briefly review current knowledge of how the immune response is regulated locally in the CNS and which cell types and molecular mechanisms are involved in shaping intracerebral immune responses...
  4. ncbi request reprint Immune function of microglia
    F Aloisi
    Neurophysiology Unit, Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Roma, Italy
    Glia 36:165-79. 2001
    ..This article focuses on the signals regulating microglia innate immune functions, the role of microglia in antigen presentation, and their possible involvement in the development of CNS immunopathology...
  5. ncbi request reprint Glia-T cell dialogue
    F Aloisi
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Roma, Italy
    J Neuroimmunol 107:111-7. 2000
    ....
  6. ncbi request reprint Relative efficiency of microglia, astrocytes, dendritic cells and B cells in naive CD4+ T cell priming and Th1/Th2 cell restimulation
    F Aloisi
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Roma, Italy
    Eur J Immunol 29:2705-14. 1999
    ..These potentially pathogenic responses could be counteracted by the high efficiency of astrocytes as well as microglia in restimulating Th2 cells...
  7. doi request reprint Lymphoid chemokines in chronic neuroinflammation
    Francesca Aloisi
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Neuroimmunol 198:106-12. 2008
    ....
  8. ncbi request reprint Opposite effects of interferon-gamma and prostaglandin E2 on tumor necrosis factor and interleukin-10 production in microglia: a regulatory loop controlling microglia pro- and anti-inflammatory activities
    F Aloisi
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Roma, Italy
    J Neurosci Res 56:571-80. 1999
    ..We suggest that the activity and role of microglia in the damaged CNS could be finely tuned by the local concentration ratio of these mediators...
  9. ncbi request reprint ATP regulates oligodendrocyte progenitor migration, proliferation, and differentiation: involvement of metabotropic P2 receptors
    C Agresti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Roma, Italy
    Brain Res Brain Res Rev 48:157-65. 2005
    ..These findings suggest that ATP, which is released in high amounts under inflammatory conditions and following cell death, might regulate remyelination processes in inflammatory demyelinating diseases of the CNS, like multiple sclerosis...
  10. ncbi request reprint Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-gamma and TNF-alpha in oligodendrocytes
    C Agresti
    Laboratory of Organ and System Pathophysiology, Istituto Superiore di Sanita, Rome, Italy
    Eur J Neurosci 10:2975-83. 1998
    ..The synergism demonstrated in the present study highlights the importance of cytokine interactions in magnifying their biological effects during brain injury and inflammation...
  11. ncbi request reprint Metabotropic P2 receptor activation regulates oligodendrocyte progenitor migration and development
    C Agresti
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Glia 50:132-44. 2005
    ..These data indicate that ATP and ADP may regulate oligodendrocyte progenitor functions by a mechanism that involves mainly activation of P2Y(1) receptors...
  12. ncbi request reprint Astrocyte cultures from human embryonic brain: characterization and modulation of surface molecules by inflammatory cytokines
    F Aloisi
    Neurobiology Section, , Rome, Italy
    J Neurosci Res 32:494-506. 1992
    ..The human astrocyte cultures developed here represent a useful in vitro model to further investigate mechanisms involved in bidirectional communication between central glia and cells of the immune system...
  13. ncbi request reprint Growth factors
    F Aloisi
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161, Rome, Italy
    Neurol Sci 24:S291-4. 2003
    ..A future challenge is to use this knowledge to boost remyelination and ameliorate clinical symptoms in patients with demyelinating diseases, like multiple sclerosis...
  14. doi request reprint Epstein-Barr virus nuclear antigen-1 B-cell epitopes in multiple sclerosis twins
    R Mechelli
    S Andrea Hospital Site, Sapienza University, Rome, Italy
    Mult Scler 17:1290-4. 2011
    ..Compared with quantitative observations, the search for qualitative changes that may characterize the immune response to Epstein-Barr virus (EBV) in multiple sclerosis (MS) has been less intense...
  15. ncbi request reprint HIV-1 Nef alters the expression of betaII and epsilon isoforms of protein kinase C and the activation of the long terminal repeat promoter in human astrocytoma cells
    E Ambrosini
    Istituto Superiore di Sanita, Rome, Italy
    Glia 27:143-51. 1999
    ..These results suggest that Nef may alter astrocytic functions by interfering with PKC expression and activation and contribute to the restriction of HIV-1 replication in astrocytes...
  16. ncbi request reprint Peripheral tissue release of interleukin-6 in patients with chronic kidney diseases: effects of end-stage renal disease and microinflammatory state
    G Garibotto
    Department of Internal Medicine, Nephrology Division, Genoa University, Genoa, Italy
    Kidney Int 70:384-90. 2006
    ..The release of IL-6 from peripheral tissues may act as a signal for the inflammatory response and contribute to functional dysregulation in uremia...