Walter Adriani

Summary

Affiliation: Istituto Superiore di Sanit
Country: Italy

Publications

  1. ncbi Preexposure during or following adolescence differently affects nicotine-rewarding properties in adult rats
    Walter Adriani
    INSERM U 588, Institut Francois Magendie, Domaine de Carreire, rue C Saint Saëns, Bordeaux Cedex, 33077, France
    Psychopharmacology (Berl) 184:382-90. 2006
  2. ncbi Short-term effects of adolescent methylphenidate exposure on brain striatal gene expression and sexual/endocrine parameters in male rats
    Walter Adriani
    Department of Cell Biology and Neurosciences, Behavioural Neuroscience Section, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161 Roma, Italy
    Ann N Y Acad Sci 1074:52-73. 2006
  3. pmc Delay aversion but preference for large and rare rewards in two choice tasks: implications for the measurement of self-control parameters
    Walter Adriani
    Behavioural Neuroscience Section, Dept, Cell Biology and Neurosciences, Istituto Superiore di Sanita, Roma, Italy
    BMC Neurosci 7:52. 2006
  4. doi Autoantibodies against opioid or glutamate receptors are associated with changes in morphine reward and physical dependence in mice
    Francesca Capone
    Section of Behavioral Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, Italy
    Psychopharmacology (Berl) 197:535-48. 2008
  5. ncbi Motor impulsivity in APP-SWE mice: a model of Alzheimer's disease
    Walter Adriani
    Behavioural Neuroscience Section, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Behav Pharmacol 17:525-33. 2006
  6. ncbi Impulsivity-anxiety-related behavior and profiles of morphine-induced analgesia in heterozygous reeler mice
    Elisa Ognibene
    Behavioral Neuroscience Section, Dept Cell Biology and Neuroscience, Istituto Superiore di Sanita, Roma, Italy
    Brain Res 1131:173-80. 2007
  7. ncbi Neurobehavioural disorders in the infant reeler mouse model: interaction of genetic vulnerability and consequences of maternal separation
    Elisa Ognibene
    Section of Behavioural Neuroscience, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy
    Behav Brain Res 177:142-9. 2007
  8. doi Gene-environment interaction during early development in the heterozygous reeler mouse: clues for modelling of major neurobehavioral syndromes
    Giovanni Laviola
    Sect Behavioral Neuroscience, Dept Cell Biology, Istituto Superiore di Sanita, Viale Regina Elena, 299, I 00161 Roma, Italy
    Neurosci Biobehav Rev 33:560-72. 2009
  9. ncbi Impulsivity and home-cage activity are decreased by lentivirus-mediated silencing of serotonin transporter in the rat hippocampus
    Francesca Zoratto
    Dept Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Neurosci Lett 548:38-43. 2013
  10. ncbi Methylphenidate administration to adolescent rats determines plastic changes on reward-related behavior and striatal gene expression
    Walter Adriani
    Department of Cell Biology and Neurosciences, Behavioral Neuroscience Section, Istituto Superiore di Sanita, Roma, Italy
    Neuropsychopharmacology 31:1946-56. 2006

Detail Information

Publications48

  1. ncbi Preexposure during or following adolescence differently affects nicotine-rewarding properties in adult rats
    Walter Adriani
    INSERM U 588, Institut Francois Magendie, Domaine de Carreire, rue C Saint Saëns, Bordeaux Cedex, 33077, France
    Psychopharmacology (Berl) 184:382-90. 2006
    ..Exposure to nicotine during periadolescence, but not similar exposure in the postadolescent period, increases nicotine self-administration in rats, but underlying mechanisms remain poorly understood...
  2. ncbi Short-term effects of adolescent methylphenidate exposure on brain striatal gene expression and sexual/endocrine parameters in male rats
    Walter Adriani
    Department of Cell Biology and Neurosciences, Behavioural Neuroscience Section, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161 Roma, Italy
    Ann N Y Acad Sci 1074:52-73. 2006
    ..Our observations suggest that adolescent MPH exposure causes only transient changes in reproductive and hormonal parameters, and a more enduring enhancement of neurobehavioral plasticity...
  3. pmc Delay aversion but preference for large and rare rewards in two choice tasks: implications for the measurement of self-control parameters
    Walter Adriani
    Behavioural Neuroscience Section, Dept, Cell Biology and Neurosciences, Istituto Superiore di Sanita, Roma, Italy
    BMC Neurosci 7:52. 2006
    ..It has been suggested that PD protocols also measure impulsivity, however, a clear dissociation has been reported between delay and probability discounting...
  4. doi Autoantibodies against opioid or glutamate receptors are associated with changes in morphine reward and physical dependence in mice
    Francesca Capone
    Section of Behavioral Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, Italy
    Psychopharmacology (Berl) 197:535-48. 2008
    ..This study characterized the role of aAbs to these receptors in behavioral modulations recruited during opioid tolerance and sensitization...
  5. ncbi Motor impulsivity in APP-SWE mice: a model of Alzheimer's disease
    Walter Adriani
    Behavioural Neuroscience Section, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Behav Pharmacol 17:525-33. 2006
    ..Together with recent findings, APP-SWE mice emerge as a suitable animal model, characterized by a number of specific behavioral alterations, resembling primary and secondary symptoms of human Alzheimer's disease...
  6. ncbi Impulsivity-anxiety-related behavior and profiles of morphine-induced analgesia in heterozygous reeler mice
    Elisa Ognibene
    Behavioral Neuroscience Section, Dept Cell Biology and Neuroscience, Istituto Superiore di Sanita, Roma, Italy
    Brain Res 1131:173-80. 2007
    ..The HZ genotype can thus represent a useful animal model for the study of behavioral disorders consequent to reduced neural plasticity...
  7. ncbi Neurobehavioural disorders in the infant reeler mouse model: interaction of genetic vulnerability and consequences of maternal separation
    Elisa Ognibene
    Section of Behavioural Neuroscience, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy
    Behav Brain Res 177:142-9. 2007
    ....
  8. doi Gene-environment interaction during early development in the heterozygous reeler mouse: clues for modelling of major neurobehavioral syndromes
    Giovanni Laviola
    Sect Behavioral Neuroscience, Dept Cell Biology, Istituto Superiore di Sanita, Viale Regina Elena, 299, I 00161 Roma, Italy
    Neurosci Biobehav Rev 33:560-72. 2009
    ..HZ may be used to disentangle interactions between genetic vulnerability and environmental factors. Such an approach could help to model the pathogenesis of neurodevelopmental psychiatric diseases...
  9. ncbi Impulsivity and home-cage activity are decreased by lentivirus-mediated silencing of serotonin transporter in the rat hippocampus
    Francesca Zoratto
    Dept Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Neurosci Lett 548:38-43. 2013
    ..In conclusion, present findings may possibly disclose novel avenues towards the development of innovative therapeutical approaches for behavioural symptoms relevant to ADHD. ..
  10. ncbi Methylphenidate administration to adolescent rats determines plastic changes on reward-related behavior and striatal gene expression
    Walter Adriani
    Department of Cell Biology and Neurosciences, Behavioral Neuroscience Section, Istituto Superiore di Sanita, Roma, Italy
    Neuropsychopharmacology 31:1946-56. 2006
    ..These modifications might in turn trigger enduring changes responsible for the adult neurobehavioral profile, that is, altered processing of incentive values and a modified flexibility/habit balance...
  11. ncbi The effect of early maternal separation on brain derived neurotrophic factor and monoamine levels in adult heterozygous reeler mice
    Elisa Ognibene
    Section of Behavioral Neuroscience, Dept Cell Biology and Neuroscience, Istituto Superiore di Sanita, Roma, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:1269-76. 2008
    ..The modulatory effects of a chronic treatment with the atypical antipsychotic olanzapine (OLZ, 1.5 mg/kg for 40 days) were also investigated...
  12. ncbi Acetyl-L-carnitine reduces impulsive behaviour in adolescent rats
    Walter Adriani
    Behavioural Neuroscience Section, Dept Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Psychopharmacology (Berl) 176:296-304. 2004
    ..The ALC treatment increased NA levels in the CC and the 5HIAA/5HT ratio in both CC and MFC. Present data suggest that ALC, a drug devoid of psychostimulant properties, may have some beneficial effects in the treatment of ADHD children...
  13. pmc Immunization with DAT fragments is associated with long-term striatal impairment, hyperactivity and reduced cognitive flexibility in mice
    Walter Adriani
    Dept Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Behav Brain Funct 8:54. 2012
    ..Here, we assessed the interplay between DAT auto-immunity and behavioural / neurochemical phenotype...
  14. doi Peculiar response to methylphenidate in adolescent compared to adult rats: a phMRI study
    Rossella Canese
    Molecular and Cellular Imaging Section, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena, 299, 00161, Rome, Italy
    Psychopharmacology (Berl) 203:143-53. 2009
    ..Adolescent rodents differ markedly from adults in several neuro-behavioural parameters. Moreover, 'paradoxical' responses to psychostimulants have been reported at this age...
  15. ncbi Evidence for enhanced neurobehavioral vulnerability to nicotine during periadolescence in rats
    Walter Adriani
    Institut National de la Santé et de la Recherche Médicale U588, Université V Segalen, Bordeaux 2, Domaine de Carreire, 33077 Bordeaux, France
    J Neurosci 23:4712-6. 2003
    ..Both these changes indicated an increased sensitivity to the addictive properties of nicotine. In conclusion, adolescence seems to be a critical developmental period, characterized by enhanced neurobehavioral vulnerability to nicotine...
  16. ncbi D-amphetamine-related reinforcing effects are reduced in mice exposed prenatally to estrogenic endocrine disruptors
    Giovanni Laviola
    Section of Behavioral Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena, 299 I 00161 Roma, Italy
    Brain Res Bull 65:235-40. 2005
    ..These data confirm that exposure to weak environmental estrogens in the period of brain sexual differentiation can influence adult behavior...
  17. doi Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas
    Eva Maria Marco
    Department Cell Biology and Neuroscience, Istituto Superiore di Sanita, Rome, Italy
    Brain Res 1257:25-31. 2009
    ..Insights into the developmental trajectories of this neuromodulatory system may help us to better understand and prevent outcomes of neonatal and adolescent cannabis exposure...
  18. ncbi Long-term effects of neonatal basal forebrain cholinergic lesions on radial maze learning and impulsivity in rats
    Maria L Scattoni
    Section of Behavioural Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Behav Pharmacol 17:517-24. 2006
    ..This animal model may thus be useful to investigate some cognitive deficits and other secondary symptoms seen in Alzheimer's disease...
  19. ncbi Behavioral and neurochemical vulnerability during adolescence in mice: studies with nicotine
    Walter Adriani
    Section of Behavioral Pathophysiology, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Roma, Italy
    Neuropsychopharmacology 29:869-78. 2004
    ..These findings support neurobiological vulnerability to drugs in adolescent humans...
  20. doi Cognitive impulsivity in animal models: role of response time and reinforcing rate in delay intolerance with two-choice operant tasks
    Walter Adriani
    Section of Behavioural Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Neuropharmacology 58:694-701. 2010
    ..Conversely, a drug-enhanced capacity to cope with delay may involve an internal ability to adjust expectancy about such a reinforcing rate...
  21. doi Social withdrawal and gambling-like profile after lentiviral manipulation of DAT expression in the rat accumbens
    Walter Adriani
    Sections of Behavioral Neuroscience and of Molecular and Cellular Imaging, Department Cell Biology and Neurosciences, Istituto Superiore di Sanita, Roma, Italy
    Int J Neuropsychopharmacol 13:1329-42. 2010
    ....
  22. ncbi Enhancement of endocannabinoid signalling during adolescence: Modulation of impulsivity and long-term consequences on metabolic brain parameters in early maternally deprived rats
    Eva Maria Marco
    Unit of Behavioural Neurosciences, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Roma, Italy
    Pharmacol Biochem Behav 86:334-45. 2007
    ..In summary, administration of URB597 during adolescence increased self-control behaviour and produced enduring brain biochemical modifications, in a model for neuropsychiatric disorders...
  23. ncbi Aspects of spatial memory and behavioral disinhibition in Tg2576 transgenic mice as a model of Alzheimer's disease
    Elisa Ognibene
    Section of Behavioural Neuroscience, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy
    Behav Brain Res 156:225-32. 2005
    ..Results clearly indicate that Tg2576 mice are characterized by a number of specific behavioral cognitive alterations, compatible with Alzheimer's disease (AD), which make them a suitable animal model for testing of novel anti-AD drugs...
  24. ncbi Behavioral effects of 6-bromoflavanone and 5-methoxy-6,8-dibromoflavanone as anxiolytic compounds
    Elisa Ognibene
    Behavioural Neuroscience Section, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:128-34. 2008
    ..At the tested doses, both compounds did not induce sedative action or compulsive behaviour. These results encourage making deeper investigations on this field...
  25. ncbi Peculiar vulnerability to nicotine oral self-administration in mice during early adolescence
    Walter Adriani
    Behavioural Pathophysiology Section, Lab F O S, Istituto Superiore di Sanita, Viale Regina Elena 299, Roma, Italy
    Neuropsychopharmacology 27:212-24. 2002
    ..The present animal model might be useful to investigate psychobiological determinants involved in early tobacco smoking in human adolescents..
  26. ncbi Elevated levels of impulsivity and reduced place conditioning with d-amphetamine: two behavioral features of adolescence in mice
    Walter Adriani
    Section of Behavioural Pathophysiology, Laboratorio Fisiopatologia O S, Istituto Superiore di Sanita, Rome, Italy
    Behav Neurosci 117:695-703. 2003
    ..Hence, 2 main features of adolescence were elevated impulsivity and restlessness, and low (or absent) rewarding efficacy of amphetamine...
  27. ncbi Risk-taking behavior in adolescent mice: psychobiological determinants and early epigenetic influence
    Giovanni Laviola
    Section of Behavioral Pathophysiology, Lab Fisiopatologia O S, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161 Roma, Italy
    Neurosci Biobehav Rev 27:19-31. 2003
    ..Actually, this model is able to show behavioral features that resemble those found in human adolescents, including vulnerability to the consumption of psychoactive drugs...
  28. ncbi Modulatory effects of two novel agonists for serotonin receptor 7 on emotion, motivation and circadian rhythm profiles in mice
    Walter Adriani
    Behavioral Neuroscience Section, Dept of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161 Rome, Italy
    Neuropharmacology 62:833-42. 2012
    ..In the next future, agonist modulation of 5-HT(7) receptors might turn out to be beneficial for sleep and/or anxiety disorders. This article is part of a Special Issue entitled 'Post-Traumatic Stress Disorder'...
  29. ncbi Restricted daily access to water and voluntary nicotine oral consumption in mice: methodological issues and individual differences
    Walter Adriani
    Behavioural Pathophysiology Section, Lab Fisiopatologia Organo Sistema, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161 Rome, Italy
    Behav Brain Res 134:21-30. 2002
    ..In conclusion, a clear-cut preference for NIC can be easily established when the drug offer is concurrent to a restricted access to water. The present paradigm may be useful to investigate issues of NIC dependence...
  30. doi Differential response to specific 5-Ht(7) versus whole-serotonergic drugs in rat forebrains: a phMRI study
    Rossella Canese
    Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Rome, Italy
    Neuroimage 58:885-94. 2011
    ..The present findings revealed two differential serotonergic sub-pathways, as evidenced by the detection of physiological vascular feedback and/or neuronal activation...
  31. doi Gambling proneness in rats during the transition from adolescence to young adulthood: a home-cage method
    Francesca Zoratto
    Section of Behavioural Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161 Rome, Italy
    Neuropharmacology 67:444-54. 2013
    ..In conclusion, methodological refinement is essential to allow the study of risk-prone behaviour during rat adolescence, thus contributing to a better understanding of psychobiological determinants of gambling...
  32. ncbi The spontaneously hypertensive-rat as an animal model of ADHD: evidence for impulsive and non-impulsive subpopulations
    Walter Adriani
    Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, Roma I 00161, Italy
    Neurosci Biobehav Rev 27:639-51. 2003
    ..Present results confirm and extend previous literature, indicating that adolescent SHRs represent a suitable animal model for the preclinical investigation of the early-onset ADHD syndrome...
  33. doi Neurobehavioral adaptations to methylphenidate: the issue of early adolescent exposure
    Eva M Marco
    Dept of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, Italy
    Neurosci Biobehav Rev 35:1722-39. 2011
    ....
  34. ncbi Spontaneous novelty seeking and amphetamine-induced conditioning and sensitization in adult mice: evidence of dissociation as a function of age at weaning
    Walter Adriani
    Section of Behavioural Pathophysiology, Lab Fisiopatologia O S, Istituto Superiore di Sanita, Viale Regina Elena 299, Roma, Italy
    Neuropsychopharmacology 27:225-36. 2002
    ..These results appear relevant to the issue of early experiences as possible risk factors for a number of psychiatric disorders in humans, including the abuse of drugs...
  35. ncbi Response to novelty, social and self-control behaviors, in rats exposed to neonatal anoxia: modulatory effects of an enriched environment
    Walter Adriani
    Section of Behavioural Neuroscience, Department Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy
    Psychopharmacology (Berl) 184:155-65. 2006
    ..Beneficial effects of stimulation by an enriched environment during the still-plastic window of adolescence are suggested in these animals...
  36. ncbi Paradoxical effects of prenatal acetylcholinesterase blockade on neuro-behavioral development and drug-induced stereotypies in reeler mutant mice
    Giovanni Laviola
    Behavioural Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy
    Psychopharmacology (Berl) 187:331-44. 2006
    ..Chlorpyrifos, a potent and reversible acetylcholinesterase blocker used as a pesticide, and the "reeler" mouse, lacking the extracellular-matrix protein Reelin, were used...
  37. doi Choice with delayed or uncertain reinforcers in rats: influence of timeout duration and session length
    Francesca Zoratto
    Department of Cell Biology and Neurosciences, Sec Behavioural Neuroscience, Istituto Superiore di Sanita, I 00161 Roma, Italy
    Synapse 66:792-806. 2012
    ..Present data demonstrate that TO and SL crucially influence rats' performance in these operant tasks. Their methodological refinement is highly relevant to validate preclinical models for inhibitory-control impairments...
  38. ncbi Nicotine self-administration impairs hippocampal plasticity
    Djoher Nora Abrous
    Institut National de la Santé et de la Recherche Médicale U259 Laboratoire de Psychobiologie des Comportements Adaptatifs, Domaine de Carreire, 33077 Bordeaux, France
    J Neurosci 22:3656-62. 2002
    ..These results raise an important additional concern for the health consequences of nicotine abuse and open new insight on the possible neural mechanisms of tobacco addiction...
  39. ncbi Early adversity and alcohol availability persistently modify serotonin and hypothalamic-pituitary-adrenal-axis metabolism and related behavior: what experimental research on rodents and primates can tell us
    Simone Macri
    Section of Behavioral Neuroscience, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Neurosci Biobehav Rev 31:172-80. 2007
    ....
  40. ncbi Peculiar response of adolescent mice to acute and chronic stress and to amphetamine: evidence of sex differences
    Giovanni Laviola
    Section of Behavioral Pathophysiology, Lab Fisiopatologia O S, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161 Rome, Italy
    Behav Brain Res 130:117-25. 2002
    ....
  41. ncbi [Psychobiological determinants of risk behavior in adolescence]
    Giovanni Laviola
    Laboratorio di Fisiopatologia di Organo e di Sistema, Istituto Superiore di Sanita, V le Regina Elena 299, 00161 Roma
    Ann Ist Super Sanita 38:279-87. 2002
    ..AIDS and car accident)...
  42. pmc Altered profiles of spontaneous novelty seeking, impulsive behavior, and response to D-amphetamine in rats perinatally exposed to bisphenol A
    Walter Adriani
    Section of Behavioral Pathophysiology, Laboratorio Fisiopatologia O S, Istituto Superiore di Sanita, Roma, Italy
    Environ Health Perspect 111:395-401. 2003
    ..This may be a cause for concern for public health, confirming that exposure to a weak environmental estrogen in the period of sexual differentiation of the brain can influence adult behavior...
  43. pmc Individual differences in gambling proneness among rats and common marmosets: an automated choice task
    Francesca Zoratto
    Section of Behavioural Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy Bambino Gesù Children s Hospital IRCCS, Rome, Italy
    Biomed Res Int 2014:927685. 2014
    ..Implementation of the PDT to species other than rats may be relevant for determining its external validity/generalizability and improving its face/construct validity. ..
  44. doi Brain processes in discounting: consequences of adolescent methylphenidate exposure
    Walter Adriani
    Section of Behavioural Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita, Viale Regina Elena 299, I 00161, Rome, Italy
    Curr Top Behav Neurosci 9:113-43. 2012
    ....
  45. ncbi Ontogenesis of behavioral sensitization and conditioned place preference induced by psychostimulants in laboratory rodents
    Ezio Tirelli
    Behavioral Neuroscience and Experimental Psychopharmacology Laboratory, Department of Cognitive Sciences, University of Liege, Boulevard du Rectorat B32, B 4000 Liege, Belgium
    Neurosci Biobehav Rev 27:163-78. 2003
    ..These age-related changes do imply very different degrees of vulnerability to drug addiction and several other neuropsychiatric disorders...
  46. ncbi Behavioural, neural and cardiovascular adaptations in mice lacking the NPY Y1 receptor
    Tania Costoli
    Department of Evolutionary and Functional Biology, Universita di Parma, Parco Area delle Scienze 11A, 43100 Parma, Italy
    Neurosci Biobehav Rev 29:113-23. 2005
    ....
  47. ncbi Specific changes in levels of autoantibodies to glutamate and opiate receptors induced by morphine administration in rats
    Oleg Granstrem
    Department of Neurology and Neurosurgery, I P Pavlov s State Medical University, 6 8 L Tolstoy s Street, 197022 St Petersburg, Russia
    Neurosci Lett 403:1-5. 2006
    ..Therefore, together with further investigations on their potential functional consequences, we propose a thorough exploration of aAbs to MDOR and to AMPA GluR1 subunit as early biomarkers signaling opiate addiction...
  48. ncbi Subchronic nicotine exposure in adolescence induces long-term effects on hippocampal and striatal cannabinoid-CB1 and mu-opioid receptors in rats
    Eva M Marco
    Dept Fisiología Fisiología Animal II, Facultad de Biologia, Universidad Complutense, Madrid, Spain
    Eur J Pharmacol 557:37-43. 2007
    ..e. cannabis and morphine/heroin when taken later in life...