Affiliation: Istituti Ortopedici Rizzoli
- Gamberi G, Morandi L, Benini S, Resca A, Cocchi S, Magagnoli G, et al. Detection of H3F3A p.G35W and p.G35R in giant cell tumor of bone by Allele Specific Locked Nucleic Acid quantitative PCR (ASLNAqPCR). Pathol Res Pract. 2018;214:89-94 pubmed publisher..We demonstrated that ASLNAqPCR is a quick, sensitive and reliable method to identify mutations of the H3F3A gene, in giant cell tumor of bone, to support diagnosis in morphologically ambiguous cases. ..
- Righi A, Mancini I, Gambarotti M, Picci P, Gamberi G, Marraccini C, et al. Histone 3.3 mutations in giant cell tumor and giant cell-rich sarcomas of bone. Hum Pathol. 2017;68:128-135 pubmed publisher..Although the presence of H3F3A mutations does not exclude with certainty a diagnosis of sarcoma, the possibility of a malignant evolution of GCTB should also be considered. ..