Research Topics
| Rosa Maria BorziSummaryAffiliation: Istituti Ortopedici Rizzoli Country: Italy Publications
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Detail Information
Publications
Matrix metalloproteinase 13 loss associated with impaired extracellular matrix remodeling disrupts chondrocyte differentiation by concerted effects on multiple regulatory factorsRosa Maria Borzi
Istituti Ortopedici Rizzoli, Bologna, Italy
Arthritis Rheum 62:2370-81. 2010..To link matrix metalloproteinase 13 (MMP-13) activity and extracellular matrix (ECM) remodeling to alterations in regulatory factors leading to a disruption in chondrocyte homeostasis...
Differential requirements for IKKalpha and IKKbeta in the differentiation of primary human osteoarthritic chondrocytesEleonora Olivotto
Istituti Ortopedici Rizzoli, Bologna, Italy
Arthritis Rheum 58:227-39. 2008..This study was undertaken to investigate the differential roles of each IKK in chondrocyte differentiation and hypertrophy...
The polyamine analogue N1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyaminesIvana Stanic'
Dipartimento di Biochimica G Moruzzi, University of Bologna, Bologna, Italy
J Cell Physiol 219:109-16. 2009..In conclusion, the results suggest that DENSPM can favour apoptosis in chondrocytes independently of its effects on polyamine metabolism and levels...
Sulforaphane protects human chondrocytes against cell death induced by various stimuliAnnalisa Facchini
Dipartimento di Biochimica G Moruzzi, University of Bologna, Bologna, Italy
J Cell Physiol 226:1771-9. 2011....
Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1Marianna Penzo
Centro Ricerca Biomedica Applicata CRBA, S Orsola Malpighi University Hospital, University of Bologna, Bologna, Italy
J Cell Physiol 218:215-27. 2009....
Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytesIvana Stanic
Dipartimento di Biochimica G Moruzzi, University of Bologna, Bologna, Italy
J Cell Physiol 216:153-61. 2008..Moreover, these results indicate that a reduction of polyamine levels not only leads to inhibition of cell proliferation, but also of caspase-mediated pathways of chondrocyte apoptosis...
Growth-related oncogene alpha induction of apoptosis in osteoarthritis chondrocytesRosa Maria Borzi
IRCCS Istituti Ortopedici Rizzoli, Bologna, Italy
Arthritis Rheum 46:3201-11. 2002..These findings are relevant to understanding the pathogenesis of OA, in view of the availability of the GROalpha chemokine in the joint space in the course of this rheumatic disease...
