Marco Alberghini

Summary

Affiliation: Istituti Ortopedici Rizzoli
Country: Italy

Publications

  1. pmc Reclassification and subtyping of so-called malignant fibrous histiocytoma of bone: comparison with cytogenetic features
    Fredrik Mertens
    Department of Clinical Genetics, University and Regional Laboratories, Skane University Hospital, Lund University, Lund, Sweden
    Clin Sarcoma Res 1:10. 2011
  2. pmc Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways
    Ymera Pignochino
    Division of Medical Oncology, University of Torino Medical School, A, O, Ordine Mauriziano, Institute for Cancer Research and Treatment Candiolo, and Regina Margherita Children s Hospital, Torino, Italy
    Mol Cancer 8:118. 2009
  3. ncbi request reprint Histochemical and ultrastructural study of an elastofibroma dorsi coexisting with a high grade spindle cell sarcoma
    M Alberghini
    Anatomia Patologica, Istituti Ortopedici Rizzoli, via di Barbiano 1 10 40136 Bologna, Italy
    Eur J Histochem 48:173-8. 2004
  4. ncbi request reprint Leiomyosarcoma of the spermatic cord: a light and ultrastructural description of one case
    Marco Alberghini
    Department of Surgical Pathology, IOR, Bologna, Italy
    Pathol Res Pract 200:487-91. 2004
  5. ncbi request reprint Desmoplastic fibroblastoma: a light and ultrastructural description of two cases
    Marco Alberghini
    Department of Surgical Pathology, Rizzoli Institute, IRCCS, Bologna, Italy
    Ultrastruct Pathol 28:149-57. 2004
  6. doi request reprint Osteosarcoma of the pelvis: a monoinstitutional experience in patients younger than 41 years
    Stefano Ferrari
    Sezione di Chemioterapia, Istituto Ortopedico Rizzoli, Via Pupilli 1, Bologna, Italy
    Tumori 98:702-8. 2012
  7. doi request reprint Neoadjuvant chemotherapy for osteosarcoma of the extremities in preadolescent patients: the Rizzoli Institute experience
    Gaetano Bacci
    Chemotherapy Unit, Department of Musculoskeletal Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy
    J Pediatr Hematol Oncol 30:908-12. 2008
  8. doi request reprint Periosteal osteosarcoma: a single-institution experience
    Marilena Cesari
    Chemotherapy Section, Rizzoli Orthopedic Institute, Bologna, Italy
    Cancer 117:1731-5. 2011
  9. doi request reprint miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy
    Fumihiko Nakatani
    Laboratory of Experimental Oncology, Rizzoli Institute, Bologna, Italy
    J Pathol 226:796-805. 2012
  10. doi request reprint Differential gene expression in classic giant cell tumours of bone: Tenascin C as biological risk factor for local relapses and metastases
    Laura Pazzaglia
    Laboratory of Experimental Oncology, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy
    Histopathology 57:59-72. 2010

Collaborators

Detail Information

Publications36

  1. pmc Reclassification and subtyping of so-called malignant fibrous histiocytoma of bone: comparison with cytogenetic features
    Fredrik Mertens
    Department of Clinical Genetics, University and Regional Laboratories, Skane University Hospital, Lund University, Lund, Sweden
    Clin Sarcoma Res 1:10. 2011
    ..abstract:..
  2. pmc Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways
    Ymera Pignochino
    Division of Medical Oncology, University of Torino Medical School, A, O, Ordine Mauriziano, Institute for Cancer Research and Treatment Candiolo, and Regina Margherita Children s Hospital, Torino, Italy
    Mol Cancer 8:118. 2009
    ..Despite improved prognosis, metastatic or relapsed OS remains largely incurable and no significant improvement has been observed in the last 20 years. Therefore, the search for alternative agents in OS is mandatory...
  3. ncbi request reprint Histochemical and ultrastructural study of an elastofibroma dorsi coexisting with a high grade spindle cell sarcoma
    M Alberghini
    Anatomia Patologica, Istituti Ortopedici Rizzoli, via di Barbiano 1 10 40136 Bologna, Italy
    Eur J Histochem 48:173-8. 2004
    ..The results obtained suggest that the coexistence of the two pathological entities is conceivably coincidental...
  4. ncbi request reprint Leiomyosarcoma of the spermatic cord: a light and ultrastructural description of one case
    Marco Alberghini
    Department of Surgical Pathology, IOR, Bologna, Italy
    Pathol Res Pract 200:487-91. 2004
    ....
  5. ncbi request reprint Desmoplastic fibroblastoma: a light and ultrastructural description of two cases
    Marco Alberghini
    Department of Surgical Pathology, Rizzoli Institute, IRCCS, Bologna, Italy
    Ultrastruct Pathol 28:149-57. 2004
    ..Mitotic figures and necrotic areas were not identified. Immunohistochemistry showed positivity for vimentin and focal positivity for smooth and human muscle actin, and flow cytometry showed the tumoral cells to be diploid...
  6. doi request reprint Osteosarcoma of the pelvis: a monoinstitutional experience in patients younger than 41 years
    Stefano Ferrari
    Sezione di Chemioterapia, Istituto Ortopedico Rizzoli, Via Pupilli 1, Bologna, Italy
    Tumori 98:702-8. 2012
    ..Information is scarce on systemic treatment of pelvic osteosarcoma because most chemotherapy protocols for osteosarcoma include patients with extremity tumors and aged up to 30-40 years...
  7. doi request reprint Neoadjuvant chemotherapy for osteosarcoma of the extremities in preadolescent patients: the Rizzoli Institute experience
    Gaetano Bacci
    Chemotherapy Unit, Department of Musculoskeletal Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy
    J Pediatr Hematol Oncol 30:908-12. 2008
    ..20%). The authors conclude that there does not seem to be any indication to treat preadolescent primary high-grade nonmetastatic osteosarcoma patients by alternative and/or more aggressive therapies...
  8. doi request reprint Periosteal osteosarcoma: a single-institution experience
    Marilena Cesari
    Chemotherapy Section, Rizzoli Orthopedic Institute, Bologna, Italy
    Cancer 117:1731-5. 2011
    ..The objective of this study was to review and analyze the clinical and treatment-related factors that influence the survival of patients with periosteal osteosarcoma who received treatment in a single institution...
  9. doi request reprint miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy
    Fumihiko Nakatani
    Laboratory of Experimental Oncology, Rizzoli Institute, Bologna, Italy
    J Pathol 226:796-805. 2012
    ..Restoration of miR-34a activity may be useful to decrease malignancy and increase tumour sensitivity to current drugs, so sparing excessive long-term toxicity to EWS patients...
  10. doi request reprint Differential gene expression in classic giant cell tumours of bone: Tenascin C as biological risk factor for local relapses and metastases
    Laura Pazzaglia
    Laboratory of Experimental Oncology, Istituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy
    Histopathology 57:59-72. 2010
    ..GCT specimens with different behaviour associated with an increased risk of local and/or distant relapses were studied...
  11. pmc Treatment of nonmetastatic Ewing's sarcoma family tumors of the spine and sacrum: the experience from a single institution
    Gaetano Bacci
    Sezione di Chemioterapia, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy
    Eur Spine J 18:1091-5. 2009
    ..We concluded that regardless of the type of local treatment even when associated with neoadjuvant therapy, ESFT in the spine and sacrum has a poor outcome and prognosis is significantly worse than that of primary ESFT in other sites...
  12. doi request reprint Ewing's sarcoma family tumors of the humerus: outcome of patients treated with radiotherapy, surgery or surgery and adjuvant radiotherapy
    Gaetano Bacci
    Department of Chemotherapy, Istituto Ortopedico Rizzoli, Bologna, Italy
    Radiother Oncol 93:383-7. 2009
    ..Local treatment for non-metastatic Ewing's sarcoma family tumors (ESFTs) is controversial. Results achieved in a single institution in patients with ESFT of the humerus are presented...
  13. pmc Fibrosarcomatous changes and expression of CD34+ and apolipoprotein-D in dermatofibrosarcoma protuberans
    Emanuela Palmerini
    Chemotherapy, Musculoskeletal Oncology Department, Istituto Ortopedico Rizzoli, Via Pupilli 1, Bologna, 40136, Italy
    Clin Sarcoma Res 2:4. 2012
    ..abstract:..
  14. doi request reprint Neoadjuvant chemotherapy with methotrexate, cisplatin, and doxorubicin with or without ifosfamide in nonmetastatic osteosarcoma of the extremity: an Italian sarcoma group trial ISG/OS-1
    Stefano Ferrari
    Istituto Ortopedico Rizzoli, Bologna, Italy
    J Clin Oncol 30:2112-8. 2012
    ..We compared two chemotherapy regimens that included methotrexate (MTX), cisplatin (CDP), and doxorubicin (ADM) with or without ifosfamide (IFO) in patients with nonmetastatic osteosarcoma of the extremity...
  15. ncbi request reprint Vincristine, doxorubicin, cyclophosfamide, actinomycin D, ifosfamide, and etoposide in adult and pediatric patients with nonmetastatic Ewing sarcoma. Final results of a monoinstitutional study
    Stefano Ferrari
    Chemotherapy, Istituto Ortopedico Rizzoli, Bologna, Italy
    Tumori 96:213-8. 2010
    ..To investigate a six-drug combination in patients with nonmetastatic Ewing sarcoma, focusing on chemotherapy-induced necrosis and chemotherapy toxicity in adult and pediatric patients...
  16. doi request reprint Synovial sarcoma: retrospective analysis of 250 patients treated at a single institution
    Emanuela Palmerini
    Department of Chemotherapy, Rizzoli Orthopedic Institute, Bologna, Italy
    Cancer 115:2988-98. 2009
    ..The optimal treatment for synovial sarcoma remains controversial. Treatment, outcome, and prognostic factors in patients treated in a single institution were examined...
  17. doi request reprint Nonresectable multiple lung metastases of high-grade osteosarcoma of the humerus: stable after twelve years. A case report
    Emanuela Palmerini
    Chemotherapy Unit, Department of Musculoskeletal Oncology, Istituto Ortopedico Rizzoli, Via Pupilli 1, Bologna, Italy
    J Bone Joint Surg Am 90:2240-4. 2008
  18. ncbi request reprint Prognostic significance of immunohistochemical expression of ezrin in non-metastatic high-grade osteosarcoma
    Stefano Ferrari
    Chemotherapy Unit, Istituto Ortopedico Rizzoli, Bologna, Italy
    Pediatr Blood Cancer 50:752-6. 2008
    ..Ezrin is a membrane-cytoskeleton linker protein involved in regulating growth and metastatic behaviour of cancer cells. The study evaluated ezrin expression and its prognostic value in patients with non-metastatic osteosarcoma...
  19. doi request reprint Expression of insulin-like growth factor system components in Ewing's sarcoma and their association with survival
    Katia Scotlandi
    Laboratory of Experimental Oncology, Orthopaedic Institute Rizzoli, Bologna, Italy
    Eur J Cancer 47:1258-66. 2011
    ..We evaluated the expression of insulin-like growth factor (IGF)-receptor (IGF-IR), insulin receptor (IR), IGF-I and some major intracellular mediators (IRS1, p-ERK) in specimens from EWS patients with primary localised untreated tumours...
  20. doi request reprint Late sarcoma development after curettage and bone grafting of benign bone tumors
    Piero Picci
    Bone Tumor Center, Istituto Ortopedico Rizzoli, Bologna, Italy
    Eur J Radiol 77:19-25. 2011
    ..Rarely sarcomas develop in previous benign lesions, after a long term disease free interval. We report the experience on these rare cases observed at a single Institution...
  21. ncbi request reprint Adjuvant and neoadjuvant chemotherapy for Ewing sarcoma family tumors in patients aged between 40 and 60: report of 35 cases and comparison of results with 586 younger patients treated with the same protocols in the same years
    Gaetano Bacci
    Department of Chemotherapy, Rizzoli Orthopaedic Institute, Bologna, Italy
    Cancer 109:780-6. 2007
    ..The clinical and pathologic features of 46 patients 40 to 60 years old with Ewing sarcoma family tumor (ESFT) diagnosed at the authors' institute between 1972 and 2000 were reviewed...
  22. doi request reprint Percutaneous CT-guided biopsy of the musculoskeletal system: results of 2027 cases
    Eugenio Rimondi
    Radiology Department, Istituto Ortopedico Rizzoli, Bologna, Italy
    Eur J Radiol 77:34-42. 2011
    ....
  23. pmc Solitary fibrous tumors of the soft tissues: imaging features with histopathologic correlations
    Zafaria G Papathanassiou
    The Rizzoli Institute, via del Barbiano 1 10, 40136, Bologna, Italy
    Clin Sarcoma Res 3:1. 2013
    ..To describe the imaging features of soft tissue solitary fibrous tumors, with histopathological correlations and clinical outcome...
  24. pmc Solitary bone lesions: which ones to worry about?
    Daniel Vanel
    Department of Radiology, The Rizzoli Institute, Bologna, Italy
    Cancer Imaging 12:409-13. 2012
    ..Nowadays, a biopsy is nevertheless always requested before treating a malignant lesion, even if suspicion is very high. But histology should integrate with the radiological signs...
  25. ncbi request reprint Fibrous dysplasia with degenerative atypia: a benign lesion potentially mistaken for sarcoma
    Franco Bertoni
    Department of Surgical Pathology, Istituti Ortopedici Rizzoli, Bologna, Italy
    Arch Pathol Lab Med 128:794-6. 2004
    ..The differential diagnosis is discussed. When radiographic and other histologic findings suggest fibrous dysplasia, the atypical nuclear changes should not, by themselves, alter the diagnosis...
  26. ncbi request reprint Evaluation of P-glycoprotein, HER-2/ErbB-2, p53, and Bcl-2 in primary tumor and metachronous lung metastases in patients with high-grade osteosarcoma
    Stefano Ferrari
    Chemotherapy Service, Department of Musculoskeletal Oncology, Istituti Ortopedici Rizzoli, Bologna, Italy
    Cancer 100:1936-42. 2004
    ..Investigation of the relation between primary tumor and metastatic disease is necessary for the identification of predictive factors for postrecurrence survival (PRS) in patients with recurrent osteosarcoma...
  27. doi request reprint NG2 expression predicts the metastasis formation in soft-tissue sarcoma patients
    Maria Serena Benassi
    Laboratory of Oncology Research, Rizzoli Orthopaedic Institute, Bologna, Italy
    J Orthop Res 27:135-40. 2009
    ....
  28. doi request reprint Biological indicators of prognosis in Ewing's sarcoma: an emerging role for lectin galactoside-binding soluble 3 binding protein (LGALS3BP)
    Diana Zambelli
    Laboratory of Oncologic Research, Istituti Ortopedici Rizzoli, Bologna, Italy
    Int J Cancer 126:41-52. 2010
    ..Thus, we propose LGALS3BP as a novel reliable indicator of prognosis, and we offer genetic signatures to the scientific communities for cross-validation and meta-analysis, which are indispensable tools for a rare tumor such as EWS...
  29. ncbi request reprint Aggressive fibromatosis of the neck treated with a combination of chemotherapy and indomethacin
    Alessandra Longhi
    Musculoskeletal Department, Istituto Ortopedico Rizzoli, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy
    Ear Nose Throat J 90:E11-5. 2011
    ..We also review the literature on cases of aggressive fibromatosis of the neck that have been reported over the past 12 years...
  30. ncbi request reprint Diagnosis and treatment of benign notochordal cell tumors of the spine: report of 3 cases and literature review
    Silvia Terzi
    Department of Oncologic and Degenerative Spine Surgery, Rizzoli Institute, Bologna, Italy
    Spine (Phila Pa 1976) 37:E1356-60. 2012
    ..Clinical case series...
  31. pmc Molecular diagnosis in Ewing family tumors: the Rizzoli experience--222 consecutive cases in four years
    Gabriella Gamberi
    Department of Pathology, Section of Molecular Biology, Rizzoli Institute, Via Di Barbiano 1 10, Bologna, Italy
    J Mol Diagn 13:313-24. 2011
    ..Finally, we collected the most prevalent breakpoints reported in the literature, indicating which exons are involved, the sequence breakpoints, and the NCBI reference sequences...
  32. doi request reprint Atypical lipomatous tumors/well-differentiated liposarcomas: clinical outcome of 67 patients
    Andreas F Mavrogenis
    Department of Orthopedics, University of Bologna, Istituto Ortopedico Rizzoli, Via Pupilli, 1, 40136, Bologna, Italy
    Orthopedics 34:e893-8. 2011
    ..Long-term follow-up is recommended for early diagnosis and treatment of local recurrences...
  33. doi request reprint MR imaging of bone metastases and choice of sequence: spin echo, in-phase gradient echo, diffusion, and contrast medium
    Daniel Vanel
    Department of Radiology, Institut Rizzoli, Bologna, Italy
    Semin Musculoskelet Radiol 13:97-103. 2009
    ....
  34. doi request reprint Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate
    Giuseppe Rossi
    Department of Interventional Angiographic Radiology, Rizzoli Orthopaedic Institute, Bologna, Italy
    Skeletal Radiol 39:161-7. 2010
    ..Aneurysmal bone cyst (ABC) is a lytic benign bone lesion representing about 1% of all primary bone tumors. The lesion causes pain and swelling, which are generally present for less than 3 months...
  35. pmc Percutaneous CT-guided biopsy of the spine: results of 430 biopsies
    Eugenio Rimondi
    Department of Radiology, Istituti Ortopedici Rizzoli, Bologna, Italy
    Eur Spine J 17:975-81. 2008
    ..In conclusion we can assert that this technique is reliable and safe and should be considered the gold standard in biopsies of the spine...
  36. pmc Histogenetic characterization of giant cell tumor of bone
    Manuela Salerno
    Laboratory for Pathophysiology, Istituto Ortopedico Rizzoli, 40136 Bologna, Italy
    Clin Orthop Relat Res 466:2081-91. 2008
    ..The increased number of giant cells in GCT may be secondary to an autocrine circuit mediated by the receptor activator of nuclear factor kB...