Cristina Tassorelli

Summary

Affiliation: IRCCS C. Mondino
Country: Italy

Publications

  1. doi request reprint Four-week trunk-specific rehabilitation treatment improves lateral trunk flexion in Parkinson's disease
    Michelangelo Bartolo
    Neurorehabilitation Unit, Institute of Neurology Casimiro Mondino Foundation IRCCS, Pavia, Italy
    Mov Disord 25:325-31. 2010
  2. doi request reprint Activation of CB2 receptors as a potential therapeutic target for migraine: evaluation in an animal model
    Rosaria Greco
    Laboratory of Neurophysiology of Integrative Autonomic Systems, Headache Science Centre, C, Mondino National Neurological Institute, 27100 Pavia, Italy
    J Headache Pain 15:14. 2014
  3. pmc Focus on therapy of primary stabbing headache
    Enrico Ferrante
    Department of Neuroscience, Niguarda Ca Granda Hospital, Milan, Italy
    J Headache Pain 11:157-60. 2010
  4. pmc Focus on therapy: hemicrania continua and new daily persistent headache
    Paolo Rossi
    Headache Clinic INI Grottaferrata, Rome, Italy
    J Headache Pain 11:259-65. 2010
  5. pmc Focus on therapy of hypnic headache
    Carlo Lisotto
    Headache Centre, Department of Neuroscience, S Vito al Tagliamento Hospital, Pordenone, Italy
    J Headache Pain 11:349-54. 2010
  6. doi request reprint Transdermal hormonal therapy in perimenstrual migraine: why, when and how?
    Cristina Tassorelli
    Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    Curr Pain Headache Rep 16:467-73. 2012
  7. doi request reprint Pisa syndrome in Parkinson's disease: clinical, electromyographic, and radiological characterization
    Cristina Tassorelli
    IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    Mov Disord 27:227-35. 2012
  8. ncbi request reprint Nitroglycerin enhances cGMP expression in specific neuronal and cerebrovascular structures of the rat brain
    C Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    J Chem Neuroanat 27:23-32. 2004
  9. ncbi request reprint Comparative analysis of the neuronal activation and cardiovascular effects of nitroglycerin, sodium nitroprusside and L-arginine
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, IRCCS Institute of Neurology C Mondino Foundation and University Centre for the Study of Adaptive Disorders and Headache UCADH, Pavia, Italy
    Brain Res 1051:17-24. 2005
  10. ncbi request reprint Nitroglycerin induces hyperalgesia in rats--a time-course study
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Eur J Pharmacol 464:159-62. 2003

Detail Information

Publications81

  1. doi request reprint Four-week trunk-specific rehabilitation treatment improves lateral trunk flexion in Parkinson's disease
    Michelangelo Bartolo
    Neurorehabilitation Unit, Institute of Neurology Casimiro Mondino Foundation IRCCS, Pavia, Italy
    Mov Disord 25:325-31. 2010
    ..Our findings show that significant improvements in axial posture and trunk mobility can be obtained through the 4-week rehabilitation programme described, with a parallel improvement in clinical status...
  2. doi request reprint Activation of CB2 receptors as a potential therapeutic target for migraine: evaluation in an animal model
    Rosaria Greco
    Laboratory of Neurophysiology of Integrative Autonomic Systems, Headache Science Centre, C, Mondino National Neurological Institute, 27100 Pavia, Italy
    J Headache Pain 15:14. 2014
    ..In this study we evaluated the role of CB2 receptors in two animal models of pain that may be relevant for migraine: the tail flick test and the formalin test performed during NTG-induced hyperalgesia...
  3. pmc Focus on therapy of primary stabbing headache
    Enrico Ferrante
    Department of Neuroscience, Niguarda Ca Granda Hospital, Milan, Italy
    J Headache Pain 11:157-60. 2010
    ..In this report, we focus on the therapy of PSH summarizing the information collected from a systematic analysis of the international literature over the period 1980-2009...
  4. pmc Focus on therapy: hemicrania continua and new daily persistent headache
    Paolo Rossi
    Headache Clinic INI Grottaferrata, Rome, Italy
    J Headache Pain 11:259-65. 2010
    ..NDPH is very difficult to treat and it responds poorly only to first-line options used for migraine or tension-type headache...
  5. pmc Focus on therapy of hypnic headache
    Carlo Lisotto
    Headache Centre, Department of Neuroscience, S Vito al Tagliamento Hospital, Pordenone, Italy
    J Headache Pain 11:349-54. 2010
    ..If these treatments prove to be ineffective or poorly tolerated, other agents, such as caffeine and melatonin, can be administered...
  6. doi request reprint Transdermal hormonal therapy in perimenstrual migraine: why, when and how?
    Cristina Tassorelli
    Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    Curr Pain Headache Rep 16:467-73. 2012
    ..In this review, we summarize clinical and preclinical data that are relevant for the role of estrogens in migraine and we discuss how estrogen modulation can be exploited positively to improve hormonal-related migraine...
  7. doi request reprint Pisa syndrome in Parkinson's disease: clinical, electromyographic, and radiological characterization
    Cristina Tassorelli
    IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    Mov Disord 27:227-35. 2012
    ..This postural abnormality deserves attention and proper early treatment to prevent comorbidities and pain...
  8. ncbi request reprint Nitroglycerin enhances cGMP expression in specific neuronal and cerebrovascular structures of the rat brain
    C Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    J Chem Neuroanat 27:23-32. 2004
    ..The data obtained sustains the idea that cGMP is an important mediator of nitroglycerin effect in vascular and neuronal structures that are critical elements for the transmission of cephalic pain...
  9. ncbi request reprint Comparative analysis of the neuronal activation and cardiovascular effects of nitroglycerin, sodium nitroprusside and L-arginine
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, IRCCS Institute of Neurology C Mondino Foundation and University Centre for the Study of Adaptive Disorders and Headache UCADH, Pavia, Italy
    Brain Res 1051:17-24. 2005
    ..Of the NO-related drugs tested in this study, only nitroglycerin confirmed its ability to activate brainstem areas implicated in nociception...
  10. ncbi request reprint Nitroglycerin induces hyperalgesia in rats--a time-course study
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Eur J Pharmacol 464:159-62. 2003
    ..Nitroglycerin induced a significant reduction in the latency of the tail flick 2 and 4 h after its administration. Similarly, formalin-induced pain-related behaviour increased significantly 2 and 4 h after nitroglycerin administration...
  11. ncbi request reprint Parthenolide is the component of tanacetum parthenium that inhibits nitroglycerin-induced Fos activation: studies in an animal model of migraine
    C Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, IRCCS Neurological Institute C Mondino Foundation and University Centre for the Study of Adaptive Disorder and Headache, Pavia, Italy
    Cephalalgia 25:612-21. 2005
    ..These findings strongly suggest that parthenolide is the component responsible for the biological activity of TP as regards its antimigraine effect and provide important information for future controlled clinical trials...
  12. ncbi request reprint Botulinum toxin and neuromotor rehabilitation: An integrated approach to idiopathic cervical dystonia
    Cristina Tassorelli
    Neurorehabilitation Unit, C Mondino Institute of Neurology Foundation, Dept of Neurological Sciences, University of Pavia, Italy
    Mov Disord 21:2240-3. 2006
    ..7 vs. -4.85 points) and subjective pain (-13.35 vs. 6.95 points) scores. Association of BTX-A therapy with a specific program of physical therapy may improve ICD treatment outcome...
  13. doi request reprint The role of rehabilitation in deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a pilot study
    Cristina Tassorelli
    Department of Neurological Sciences, Interdepartmental Centre of Research on Parkinson s Disease ICRPD, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    Parkinsonism Relat Disord 15:675-81. 2009
    ..The reported findings suggest that rehabilitation may play an important role in the correction of specific functional impairments caused by or associated with DBS in PD...
  14. doi request reprint The usefulness and applicability of a basic headache diary before first consultation: results of a pilot study conducted in two centres
    C Tassorelli
    University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Cephalalgia 28:1023-30. 2008
    ..Specificity was 58% for M and TTH, 87% for MOH. Combined use of a diagnostic diary and clinical interview is recommended from the first consultation for headache...
  15. doi request reprint Dysphagia in multiple sclerosis: from pathogenesis to diagnosis
    Cristina Tassorelli
    Department of Neurological Sciences, University of Pavia, Via Mondino 2, 27100, Pavia, Italy
    Neurol Sci 29:S360-3. 2008
    ..An integrated approach is proposed to define the severity of dysphagia and to devise the most appropriate therapeutic/rehabilitative methodology...
  16. ncbi request reprint Nitroglycerin-induced activation of monoaminergic transmission in the rat
    C Tassorelli
    IRCCS Neurological Institute, C Mondino Foundation, Pavia, Italy
    Cephalalgia 22:226-32. 2002
    ..These data might therefore help to clarify the mechanisms underlying the delayed migraine attack observed in migraine sufferers after systemic administration of nitroglycerin...
  17. ncbi request reprint Behavioral responses and Fos activation following painful stimuli in a rodent model of Parkinson's disease
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, Neurological Institute C Mondino, Pavia, Italy
    Brain Res 1176:53-61. 2007
    ....
  18. doi request reprint Facilitated temporal summation of pain at spinal level in Parkinson's disease
    Armando Perrotta
    Department of Neurology, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Mov Disord 26:442-8. 2011
    ....
  19. ncbi request reprint Effects of nimesulide on nitric oxide-induced hyperalgesia in humans--a neurophysiological study
    Giorgio Sandrini
    Psychophysiology of Pain Laboratory, University Center for Adaptive Disorders and Headache, University of Pavia, Via Palestro 3, 27100 Pavia, Italy
    Eur J Pharmacol 450:259-62. 2002
    ..These data suggest a central effect for nimesulide, possibly related to a reduction of nociceptive activity at spinal level...
  20. doi request reprint Oral nitric-oxide donor glyceryl-trinitrate induces sensitization in spinal cord pain processing in migraineurs: a double-blind, placebo-controlled, cross-over study
    Armando Perrotta
    Headache Science Center, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Eur J Pain 15:482-90. 2011
    ..In migraineurs the susceptibility to develop migraine attack after GTN administration seems to be a specific trait of a subgroup of patients linked to a supersensitivity of the pain system to GTN...
  21. doi request reprint Role of central dopaminergic circuitry in pain processing and nitroglycerin-induced hyperalgesia
    Rosaria Greco
    Interdepartmental Research Center for Parkinson s Disease, IRCCS Neurological Institute C Mondino, Pavia, Italy
    Brain Res 1238:215-23. 2008
    ....
  22. ncbi request reprint Relationship between hallucinations, delusions, and rapid eye movement sleep behavior disorder in Parkinson's disease
    Claudio Pacchetti
    Parkinson s Disease and Movement Disorders Unit, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Mov Disord 20:1439-48. 2005
    ..92), disease duration (OR, 2.46), advanced age (OR, 2.34), and severity of motor symptoms (OR, 2.06). These results suggest that RBD is widely associated with psychosis in PD...
  23. doi request reprint Temporal profile of vascular changes induced by systemic nitroglycerin in the meningeal and cortical districts
    Rosaria Greco
    IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    Cephalalgia 31:190-8. 2011
    ..Systemic nitroglycerin (NTG), a NO donor, is a well-accepted experimental model of migraine. In this study we have examined the effects of NTG on the meningeal and cortical blood flow in rats...
  24. pmc Effects of anandamide in migraine: data from an animal model
    Rosaria Greco
    Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation, University of Pavia, Via Mondino, 2, 27100 Pavia, Italy
    J Headache Pain 12:177-83. 2011
    ..The study confirms that a dysfunction of the endocannabinoid system may contribute to the development of migraine attacks and that a pharmacological modulation of CB receptors can be useful for the treatment of migraine pain...
  25. ncbi request reprint Prostaglandins, glutamate and nitric oxide synthase mediate nitroglycerin-induced hyperalgesia in the formalin test
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Center for the Study of Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Eur J Pharmacol 534:103-7. 2006
    ..The present findings point to the role of prostaglandins, NO synthesis and glutamate activity in the induction of nitroglycerin-induced hyperalgesia...
  26. ncbi request reprint Central components of the analgesic/antihyperalgesic effect of nimesulide: studies in animal models of pain and hyperalgesia
    Cristina Tassorelli
    Laboratories of Integrative Autonomic Systems and Neurophysiology of Pain, IRCCS Institute of Neurology C Mondino Foundation, University Center for Adaptive Disorders and Headache, Pavia, Italy
    Drugs 63:9-22. 2003
    ....
  27. doi request reprint Effect of sex and estrogens on neuronal activation in an animal model of migraine
    Rosaria Greco
    Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation and University of Pavia, Pavia, Italy
    Headache 53:288-96. 2013
    ..In this study, we evaluated the influence of sex and estrogen treatment on nitroglycerin (NTG)-induced neuronal activation in the rat brain...
  28. ncbi request reprint Activation of the transcription factor NF-kappaB in the nucleus trigeminalis caudalis in an animal model of migraine
    Rosaria Greco
    Laboratory of Pathophysiology of Integrative Autonomic Systems, IRCCS Neurological Institute C Mondino Foundation and University Centre for the Study of Adaptive Disorder and Headache UCADH, Via Palestro 3, 27100 Pavia, Italy
    Neurotoxicology 26:795-800. 2005
    ..Furthermore, these findings pave the way to new bio-molecular and pharmacological avenues for the development of innovative migraine therapies...
  29. ncbi request reprint A role for brain cyclooxygenase-2 and prostaglandin-E2 in migraine: effects of nitroglycerin
    Cristina Tassorelli
    IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Int Rev Neurobiol 82:373-82. 2007
    ..This activity may explain the pronociceptive effect of NTG described in animal and human models of pain. Most importantly, these findings point to mediators and areas that may be relevant for migraine pathogenesis and treatment...
  30. ncbi request reprint Neuroprotective effect of nitroglycerin in a rodent model of ischemic stroke: evaluation of Bcl-2 expression
    Rosaria Greco
    IRCCS C Mondino Institute of Neurology Foundation, 27100 Pavia, Italy
    Int Rev Neurobiol 82:423-35. 2007
    ....
  31. doi request reprint IkappaB-alpha expression following transient focal cerebral ischemia is modulated by nitric oxide
    Rosaria Greco
    University of Pavia, Pavia, Italy
    Brain Res 1372:145-51. 2011
    ..These findings suggest that NO of neuronal and inducible origin promotes NF-κB activation via IkB-alpha modulation and mediates ischemic-related damage in the brain following ischemia...
  32. doi request reprint Effect of a contraceptive pill containing estradiol valerate and dienogest (E2V/DNG) in women with menstrually-related migraine (MRM)
    Rossella E Nappi
    Department Obstetric and Gynecology, University of Pavia, Italy
    Contraception 88:369-75. 2013
    ..The characteristics of a contraceptive pill containing estradiol valerate/dienogest (E2V/DNG) might be of potential benefit in women with menstrually related migraine (MRM) who choose to use oral contraception for birth control...
  33. doi request reprint Sexual function and distress in women treated for primary headaches in a tertiary university center
    Rossella E Nappi
    Research Centre for Reproductive Medicine, Section of Obstetrics and Gynecology, IRCCS S Matteo Foundation, Department of Morphological, Eidological and Clinical Sciences, University of Pavia, Pavia, Italy
    J Sex Med 9:761-9. 2012
    ..Primary headaches are common in women and impact on their quality of life and psychosocial functioning. Few data are available on sexuality in female headache sufferers...
  34. doi request reprint Lack of trigemino-cervical reflexes in progressive supranuclear palsy
    Michelangelo Bartolo
    Department of Neurological Sciences, University of Pavia, Pavia, Italy
    Mov Disord 23:1475-9. 2008
    ..These findings indicate that PSP patients are unable to react to the painful stimuli to the face, suggesting a generalized impairment of the brainstem circuits mediating TCRs...
  35. ncbi request reprint Unilateral lesion of the subthalamic nucleus enhances cortical fos expression associated with focally evoked seizures in the rat
    Fabio Blandini
    Laboratory of Functional Neurochemistry, IRCCS Neurological Institute C Mondino, Via Mondino, 2, 27100 Pavia, Italy
    Brain Res 1101:145-50. 2006
    ..Abolishing the STN control over the basal ganglia output may therefore play a facilitatory role on cortical activation associated with limbic seizures...
  36. ncbi request reprint Long-term evaluation of the effect of quetiapine on hallucinations, delusions and motor function in advanced Parkinson disease
    Francesca Mancini
    Parkinson s Disease and Movement Disorders Unit, C Mondino Neurological Institute, IRCCS, Pavia, Italy
    Clin Neuropharmacol 27:33-7. 2004
    ....
  37. ncbi request reprint Effects of dopaminergic stimulation on peripheral markers of apoptosis: relevance to Parkinson's disease
    F Blandini
    IRCCS C Mondino, Via Palestro 3, Pavia, Italy
    Neurol Sci 24:157-8. 2003
    ..Our results show that dopaminergic stimulation is associated with complex changes in regulatory proteins of apoptosis...
  38. pmc Botulinum toxin type-A in the prophylactic treatment of medication-overuse headache: a multicenter, double-blind, randomized, placebo-controlled, parallel group study
    Giorgio Sandrini
    Headache Science Center, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    J Headache Pain 12:427-33. 2011
    ....
  39. pmc An electronic diary on a palm device for headache monitoring: a preliminary experience
    Marta Allena
    Headache Science Centre, C Mondino National Institute of Neurology Foundation IRCCS, Pavia, Italy
    J Headache Pain 13:537-41. 2012
    ..The level of patient compliance was good. The patients appreciated the electronic headache diary, deeming it easy to understand and to use (fill in); most of the patients rated the palm device handier than the traditional paper version...
  40. doi request reprint Modulation of RAGE isoforms expression in the brain and plasma of rats exposed to transient focal cerebral ischemia
    Rosaria Greco
    Laboratory of Neurophysiology of Integrative Autonomic Systems and Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation and University of Pavia, Via Mondino, 2, 27100, Pavia, Italy
    Neurochem Res 37:1508-16. 2012
    ..These modifications are accompanied by a decrease in the plasma levels of soluble RAGE, thereby suggesting a potential role for soluble RAGE as a peripheral biomarker of focal ischemia...
  41. ncbi request reprint Secondary cervical dystonia in iatrogenic hypoparathyroidism associated with extensive brain calcifications
    Francesca Mancini
    Parkinson s Disease and Movement Disorders Unit, C Mondino Institute of Neurology Foundation, Pavia, Italy
    Funct Neurol 21:165-6. 2006
    ..This case may prove to be, after a review of literature, the first report of CD secondary to iatrogenic hypoparathyroidism in a patient with extensive brain calcifications...
  42. doi request reprint Use of complementary and alternative medicine by patients with cluster headache: results of a multi-centre headache clinic survey
    Paolo Rossi
    Headache Centre, INI Grottaferrata, Rome, Italy
    Complement Ther Med 16:220-7. 2008
    ..To evaluate the rates, pattern, satisfaction with, and presence of predictors of complementary and alternative medicine (CAM) use in a clinical population of patients with cluster headache (CH)...
  43. ncbi request reprint Changes in nociceptive flexion reflex threshold across the menstrual cycle in healthy women
    Cristina Tassorelli
    Psychophysiology of Pain Laboratory, University Centre for Adaptive Disorders and Headache UCADH, IRCCS C Mondino Foundation, Department of Neurological Sciences, University of Pavia, Italy
    Psychosom Med 64:621-6. 2002
    ..We assessed the influence of changes in steroid hormones across the menstrual cycle on the spinal nociceptive reflex...
  44. ncbi request reprint A questionnaire on sleep and mental disorders in Parkinson's disease (QSMDPD): development and application of a new screening tool
    Claudio Pacchetti
    Parkinson s Disease and Movement Disorders Unit, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Funct Neurol 19:83-99. 2004
    ..This high compliance suggests that the QSMDPD is a promising tool for collecting data on sleep and mental disorders in large samples of PD patients. A short version will be administered as a follow-up tool...
  45. ncbi request reprint Selective stimulation of striatal dopamine receptors of the D1- or D2-class causes opposite changes of fos expression in the rat cerebral cortex
    Fabio Blandini
    Laboratory of Functional Neurochemistry, IRCCS C Mondino, Pavia, Italy
    Eur J Neurosci 17:763-70. 2003
    ..Our results confirm that striatal D1 dopamine receptors play a central role in the modulation of cortical activity, thus providing additional information on the functional interaction between basal ganglia circuitry and cerebral cortex...
  46. pmc Diagnostic and therapeutic errors in trigeminal autonomic cephalalgias and hemicrania continua: a systematic review
    Michele Viana
    Headache Science Center C, Mondino National Institute of Neurology Foundation, IRCCS, Via Mondino 2, Pavia 27100, Italy
    J Headache Pain 14:14. 2013
    ..Greater knowledge of and education about these disorders, among both primary care physicians and headache specialists, might contribute to improving the quality of life of TACs and HC patients...
  47. doi request reprint Early rehabilitation after surgery improves functional outcome in inpatients with brain tumours
    Michelangelo Bartolo
    Neurorehabilitation Unit, IRCCS NEUROMED Mediterranean Neurological Institute, Via Atinense, 18, 86077 Pozzilli, Isernia, Italy
    J Neurooncol 107:537-44. 2012
    ..Rehabilitation after surgery can improve functional outcome, justifying the delivery of rehabilitation services, even during the acute phase, to BTs inpatients, irrespective of tumour type...
  48. doi request reprint Differences in the personality profile of medication-overuse headache sufferers and drug addict patients: a comparative study using MMPI-2
    Federica Galli
    Department of Child and Adolescent Neurology, Psychiatry and Rehabilitation, Sapienza University of Rome, Italy
    Headache 51:1212-27. 2011
    ..The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, comparing MOH, episodic headache, substance addicts (SA) vs healthy controls...
  49. doi request reprint Reduced habituation of trigeminal reflexes in patients with episodic cluster headache during cluster period
    A Perrotta
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Cephalalgia 28:950-9. 2008
    ..The lack of habituation in CH, more pronounced than in migraine, points to abnormal processing of sensory stimuli at the trigeminal level that could be driven by hypothalamic dysfunction during the cluster period...
  50. ncbi request reprint Effects of acute and chronic restraint stress on nitroglycerin-induced hyperalgesia in rats
    A Costa
    Institute of Neurology IRCCS C Mondino, University Center for Adaptive Disorders and Headache UCADH, University of Pavia, Italy
    Neurosci Lett 383:7-11. 2005
    ....
  51. ncbi request reprint Effects of the intrastriatal administration of selective dopaminergic agonists on Fos expression in the rat brain
    F Blandini
    IRCCS C Mondino, Via Palestro 3, Pavia, Italy
    Neurol Sci 23:S57-8. 2002
    ..They also provide new information on a class of drugs--the dopamine agonists--whose role in the therapeutic strategy of Parkinson's disease is continuously evolving...
  52. ncbi request reprint Modifications of apoptosis-related protein levels in lymphocytes of patients with Parkinson's disease. The effect of dopaminergic treatment
    F Blandini
    Laboratory of Functional Neurochemistry, Neurological Institute C Mondino, Pavia, Italy
    J Neural Transm 111:1017-30. 2004
    ....
  53. ncbi request reprint Selective lesion of the substantia nigra pars reticulata reduces the cortical Fos expression induced by stimulation of striatal D1-like receptors, in the rat
    F Blandini
    Laboratory of Functional Neurochemistry, IRCCS Neurological Institute C Mondino, Via Mondino 2, 27100 Pavia, Italy
    Exp Neurol 200:240-4. 2006
    ..These findings confirm the prominent role of the SNr in the transmission of striatofugal signals to functionally different cortical areas...
  54. ncbi request reprint Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headaches
    G Sances
    Headache Unit, University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Foundation Institute of Neurology, Pavia, Italy
    Cephalalgia 24:110-9. 2004
    ..6%, specificity 100% and accuracy 92.9%. NPT is an easy, low-cost and reliable method for supporting the diagnosis of migraine without aura and cluster headache...
  55. pmc From drug-induced headache to medication overuse headache. A short epidemiological review, with a focus on Latin American countries
    Marta Allena
    IRCCS Neurological Institute C Mondino Foundation, University Centre for Headache and Adaptive Disorders, Pavia Section, Via Mondino 2, 27100 Pavia, Italy
    J Headache Pain 10:71-6. 2009
    ..Limited amount of data exists on the burden and impact of MOH in Latin American Countries. In this review, we summarise the reliable information from the literature on the epidemiological impact of MOH...
  56. doi request reprint An electrophysiological approach to the diagnosis of neurogenic dysphagia: implications for botulinum toxin treatment
    E Alfonsi
    Spinal and Cranial Reflexes Laboratory, Fondazione Istituto Neurologico C Mondino IRCCS, Pavia, Italy
    J Neurol Neurosurg Psychiatry 81:54-60. 2010
    ....
  57. ncbi request reprint Electrophysiologic patterns of oral-pharyngeal swallowing in parkinsonian syndromes
    E Alfonsi
    Spinal and Cranial Reflexes Laboratory, Department of Neurological Sciences, Universita di Pavia, Pavia, Italy
    Neurology 68:583-9. 2007
    ....
  58. doi request reprint Pharmacogenomics of episodic migraine: time has come for a step forward
    Michele Viana
    Headache Science Centre, C Mondino National Institute of Neurology Foundation, IRCCS, Pavia, Italy
    Pharmacogenomics 15:541-9. 2014
    ..Our knowledge on the pharmacogenomics of migraine is growing too slowly, and concerted measures should be undertaken to speed up the process. ..
  59. pmc Advice alone versus structured detoxification programmes for complicated medication overuse headache (MOH): a prospective, randomized, open-label trial
    Paolo Rossi
    Headache Clinic, INI Grottaferrata, Via S, Anna s, N, C, 00046, Grottaferrata, Rome, Italy
    J Headache Pain 14:10. 2013
    ....
  60. doi request reprint Intestinal dysmotility and enteric neurochemical changes in a Parkinson's disease rat model
    Mario Colucci
    Department of Legal Medicine, Forensic Sciences and Pharmaco Toxicology, University of Pavia, Pavia, Italy
    Auton Neurosci 169:77-86. 2012
    ....
  61. doi request reprint Eletriptan
    Giorgio Sandrini
    IRCCS C Mondino Institute of Neurology Foundation, Department of Neurology, Via Mondino 2, Pavia, Italy
    Expert Opin Drug Metab Toxicol 5:1587-98. 2009
    ..Eletriptan showed the most favorable cost-effectiveness profile when compared with other agents in its class...
  62. doi request reprint The endocannabinoid system and migraine
    Rosaria Greco
    Headache Science Centre, IRCCS Neurological Institute C Mondino Foundation, Pavia, Italy
    Exp Neurol 224:85-91. 2010
    ....
  63. ncbi request reprint The effects on the central nervous system of nitroglycerin--putative mechanisms and mediators
    C Tassorelli
    Neurological Institute IRCCS C Mondino, University of Pavia, Italy
    Prog Neurobiol 57:607-24. 1999
    ..Double labeling immunocytochemical and neuropharmacological studies have provided information on the putative neurotransmitters and neurochemical mechanisms involved in nitroglycerin-induced neuronal activation...
  64. pmc Focus on therapy of the Chapter IV headaches provoked by exertional factors: primary cough headache, primary exertional headache and primary headache associated with sexual activity
    Marta Allena
    Headache Science Centre, IRCCS C Mondino National Neurological Institute Foundation, Pavia, Italy
    J Headache Pain 11:525-30. 2010
    ..In this short review, we illustrate the possible treatment strategies on the basis of information collected from a systematic analysis of the international literature...
  65. pmc Focus on the management of thunderclap headache: from nosography to treatment
    E Ferrante
    Headache Centre, Neurosciences Department, Niguarda Ca Granda Hospital, Milan, Italy
    J Headache Pain 12:251-8. 2011
    ..In this review, we focus on the management of TCH, paying particular attention to the diagnostic work up and treatment of the condition...
  66. pmc Estimation of human trunk movements by wearable strain sensors and improvement of sensor's placement on intelligent biomedical clothes
    Paolo Tormene
    Department of Computer Engineering and Systems Science, University of Pavia, Pavia, Italy
    Biomed Eng Online 11:95. 2012
    ....
  67. ncbi request reprint Electrophysiological evidence for trigeminal neuron sensitization in patients with migraine
    Giorgio Sandrini
    Laboratory of Pain Psychophysiology, Department of Neurological Sciences, University Center for Adaptive Disorders and Headache, University of Pavia, Via Palestro 3, 27100 Pavia, Italy
    Neurosci Lett 317:135-8. 2002
    ..These findings suggest that sensorimotor mechanisms and/or pain control systems at the trigeminal level are impaired in migraine. The bilateral location of these abnormalities seems to point to a centrally located dysfunction...
  68. ncbi request reprint Uncommon primary headaches
    Giorgio Sandrini
    University Center for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Curr Opin Neurol 19:299-304. 2006
    ..The recent classification offers an interesting opportunity to evaluate the clinical role and to discuss the mechanisms of some of the more relevant uncommon primary headaches...
  69. ncbi request reprint Neurochemical mechanisms of nitroglycerin-induced neuronal activation in rat brain: a pharmacological investigation
    C Tassorelli
    Neurological Institute C Mondino, University of Pavia, Italy
    Neuropharmacology 36:1417-24. 1997
    ..Nitric oxide seems to represent the most important mediator of this phenomenon. The sympathetic system and prostaglandin synthesis are also likely to be involved...
  70. doi request reprint Functional and neurochemical changes of the gastrointestinal tract in a rodent model of Parkinson's disease
    F Blandini
    Interdepartmental Research Center for Parkinson s Disease CRIMP, Neurological Institute C Mondino, Pavia, Pavia, Italy
    Neurosci Lett 467:203-7. 2009
    ....
  71. doi request reprint Role of calcitonin gene-related peptide and substance P in different models of pain
    R Greco
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Cephalalgia 28:114-26. 2008
    ....
  72. ncbi request reprint Reciprocal circuits involved in nitroglycerin-induced neuronal activation of autonomic regions and pain pathways: a double immunolabeling and tract-tracing study
    C Tassorelli
    University Center for Adaptive Disorders and Headache UCADH, Neurological Institute C Mondino Foundation, University of Pavia, Via Palestro, 3, 27100, Pavia, Italy
    Brain Res 842:294-310. 1999
    ..These data confirm and expand on our previous findings and demonstrate that nitroglycerin activates a complex set of structures that are functionally and structurally interconnected to articulate an integrated response...
  73. ncbi request reprint Functional changes of the basal ganglia circuitry in Parkinson's disease
    F Blandini
    Neurological Institute C Mondino, Pavia, Italy
    Prog Neurobiol 62:63-88. 2000
    ..Drugs capable of antagonizing the effects of glutamate might represent, in the next future, a valuable tool for the development of new symptomatic and neuroprotective strategies for therapy of Parkinson's disease...
  74. ncbi request reprint Peripheral levels of BDNF and NGF in primary headaches
    F Blandini
    Laboratory of Functional Neurochemistry, Neurological Institute C Mondino, Pavia, Italy
    Cephalalgia 26:136-42. 2006
    ....
  75. pmc A narrative review on the management of medication overuse headache: the steep road from experience to evidence
    Paolo Rossi
    IRCCS Neurological Institute C Mondino Foundation, University Centre for Headache and Adaptive Disorders UCADH, Pavia Section, Pavia, Italy
    J Headache Pain 10:407-17. 2009
    ....
  76. ncbi request reprint Combined evaluation of pupillary and cardiovascular responses to cold pressor test in cluster headache patients
    C Tassorelli
    Headache Center and Autonomic Unit, Institute of Neurology IRCCS C Mondino Foundation, University of Pavia, Italy
    Cephalalgia 18:668-74. 1998
    ..These data suggest a systemic sympathetic hyperactivation in response to CPT in CH patients. An oculocephalic sympathetic hypofunction is possibly associated as well as an altered opioid neuromodulation...
  77. ncbi request reprint Neurotensin-induced miosis: the role of dopaminergic pathways
    C Tassorelli
    Department of Neurology, C Mondino Foundation, University of Pavia, Italy
    Peptides 11:1309-11. 1990
    ..Our data confirm previous observations regarding the miotic activity of neurotensin and suggest that the dopaminergic system plays an important role in the miotic effect of neurotensin...
  78. doi request reprint Medication overuse headache and applicability of the ICHD-II diagnostic criteria: 1-year follow-up study (CARE I protocol)
    N Ghiotto
    Headache Unit and University Centre for Adaptive Disorders and Headache, Mondino Institute of Neurology Foundation, Pavia, Italy
    Cephalalgia 29:233-43. 2009
    ..In addition, the present findings point to the need for a more objective criterion to quantify headache frequency after drug withdrawal...
  79. ncbi request reprint Dynamic evaluation by TV-pupillometry of the mydriatic effect of ibopamine solution. Controlled studies
    G Micieli
    Department of Neurology, C Mondino Foundation, University of Pavia, Italy
    Arzneimittelforschung 40:150-6. 1990
    ..The effect of ibopamine 1% on the pupillary reflex to near vision is slight, while on the reflex to light stimulus it is essentially comparable to that of tropicamide...
  80. ncbi request reprint Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease
    Alessio Di Fonzo
    Department of Clinical Genetics, Erasmus MC Rotterdam, Rotterdam, The Netherlands
    Eur J Hum Genet 14:322-31. 2006
    ..These data have implications both for understanding the molecular mechanisms of PD, and for directing the genetic screening in clinical practice...
  81. ncbi request reprint Cardiovascular dysautonomia as a cause of falls in Parkinson's disease
    Emilia Martignoni
    Unit of Neurorehabilitation and Movement Disorders, IRCCS S Maugeri Foundation, Scientific Institute of Veruno NO and Department of Medical Sciences, University of Piemonte Orientale A Avogadro, Novara, Italy
    Parkinsonism Relat Disord 12:195-204. 2006
    ....