Giuseppe Nappi

Summary

Affiliation: IRCCS C. Mondino
Country: Italy

Publications

  1. pmc Diagnostic and therapeutic errors in trigeminal autonomic cephalalgias and hemicrania continua: a systematic review
    Michele Viana
    Headache Science Center C, Mondino National Institute of Neurology Foundation, IRCCS, Via Mondino 2, Pavia 27100, Italy
    J Headache Pain 14:14. 2013
  2. pmc Medical healthcare use in Parkinson's disease: survey in a cohort of ambulatory patients in Italy
    Marco Cosentino
    Department of Clinical Medicine, Section of Experimental and Clinical Pharmacology, University of Insubria, Varese, Italy
    BMC Health Serv Res 5:26. 2005
  3. ncbi request reprint Tolerability of the triptans: clinical implications
    Giuseppe Nappi
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Foundation, University of Pavia, Italy
    Drug Saf 26:93-107. 2003
  4. pmc Introduction to the new International Classification of Headache Disorders
    Giuseppe Nappi
    Department of Neurology and Otorhinolaryngology, University of Rome La Sapienza, Rome, Italy
    J Headache Pain 6:203-4. 2005
  5. doi request reprint Chronic daily headache
    Giuseppe Nappi
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Italy
    Expert Rev Neurother 8:361-84. 2008
  6. doi request reprint The role of rehabilitation in deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a pilot study
    Cristina Tassorelli
    Department of Neurological Sciences, Interdepartmental Centre of Research on Parkinson s Disease ICRPD, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    Parkinsonism Relat Disord 15:675-81. 2009
  7. doi request reprint Oral nitric-oxide donor glyceryl-trinitrate induces sensitization in spinal cord pain processing in migraineurs: a double-blind, placebo-controlled, cross-over study
    Armando Perrotta
    Headache Science Center, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Eur J Pain 15:482-90. 2011
  8. pmc Effects of anandamide in migraine: data from an animal model
    Rosaria Greco
    Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation, University of Pavia, Via Mondino, 2, 27100 Pavia, Italy
    J Headache Pain 12:177-83. 2011
  9. pmc Focus on therapy: hemicrania continua and new daily persistent headache
    Paolo Rossi
    Headache Clinic INI Grottaferrata, Rome, Italy
    J Headache Pain 11:259-65. 2010
  10. pmc Botulinum toxin type-A in the prophylactic treatment of medication-overuse headache: a multicenter, double-blind, randomized, placebo-controlled, parallel group study
    Giorgio Sandrini
    Headache Science Center, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    J Headache Pain 12:427-33. 2011

Detail Information

Publications84

  1. pmc Diagnostic and therapeutic errors in trigeminal autonomic cephalalgias and hemicrania continua: a systematic review
    Michele Viana
    Headache Science Center C, Mondino National Institute of Neurology Foundation, IRCCS, Via Mondino 2, Pavia 27100, Italy
    J Headache Pain 14:14. 2013
    ..Greater knowledge of and education about these disorders, among both primary care physicians and headache specialists, might contribute to improving the quality of life of TACs and HC patients...
  2. pmc Medical healthcare use in Parkinson's disease: survey in a cohort of ambulatory patients in Italy
    Marco Cosentino
    Department of Clinical Medicine, Section of Experimental and Clinical Pharmacology, University of Insubria, Varese, Italy
    BMC Health Serv Res 5:26. 2005
    ..The present study was devised to describe the type of and reasons for medical healthcare resource use in persons with PD attending a Centre for PD and Movement Disorders, and to examine drug prescriptions issued on such occasions...
  3. ncbi request reprint Tolerability of the triptans: clinical implications
    Giuseppe Nappi
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Foundation, University of Pavia, Italy
    Drug Saf 26:93-107. 2003
    ..There is no evidence of a teratogenic risk of triptans in pregnant women taking these drugs...
  4. pmc Introduction to the new International Classification of Headache Disorders
    Giuseppe Nappi
    Department of Neurology and Otorhinolaryngology, University of Rome La Sapienza, Rome, Italy
    J Headache Pain 6:203-4. 2005
    ..All the headaches are classified into groups and subgroups to provide the level of diagnosis necessary for each user...
  5. doi request reprint Chronic daily headache
    Giuseppe Nappi
    University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Italy
    Expert Rev Neurother 8:361-84. 2008
    ..This article reviews various aspects of CDH: classification issues, pathophysiological hypotheses and therapeutic (pharmacological and nonpharmacological) approaches...
  6. doi request reprint The role of rehabilitation in deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a pilot study
    Cristina Tassorelli
    Department of Neurological Sciences, Interdepartmental Centre of Research on Parkinson s Disease ICRPD, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    Parkinsonism Relat Disord 15:675-81. 2009
    ..The reported findings suggest that rehabilitation may play an important role in the correction of specific functional impairments caused by or associated with DBS in PD...
  7. doi request reprint Oral nitric-oxide donor glyceryl-trinitrate induces sensitization in spinal cord pain processing in migraineurs: a double-blind, placebo-controlled, cross-over study
    Armando Perrotta
    Headache Science Center, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Eur J Pain 15:482-90. 2011
    ..In migraineurs the susceptibility to develop migraine attack after GTN administration seems to be a specific trait of a subgroup of patients linked to a supersensitivity of the pain system to GTN...
  8. pmc Effects of anandamide in migraine: data from an animal model
    Rosaria Greco
    Headache Science Centre, IRCCS National Neurological Institute C Mondino Foundation, University of Pavia, Via Mondino, 2, 27100 Pavia, Italy
    J Headache Pain 12:177-83. 2011
    ..The study confirms that a dysfunction of the endocannabinoid system may contribute to the development of migraine attacks and that a pharmacological modulation of CB receptors can be useful for the treatment of migraine pain...
  9. pmc Focus on therapy: hemicrania continua and new daily persistent headache
    Paolo Rossi
    Headache Clinic INI Grottaferrata, Rome, Italy
    J Headache Pain 11:259-65. 2010
    ..NDPH is very difficult to treat and it responds poorly only to first-line options used for migraine or tension-type headache...
  10. pmc Botulinum toxin type-A in the prophylactic treatment of medication-overuse headache: a multicenter, double-blind, randomized, placebo-controlled, parallel group study
    Giorgio Sandrini
    Headache Science Center, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Via Mondino 2, 27100 Pavia, Italy
    J Headache Pain 12:427-33. 2011
    ....
  11. ncbi request reprint Neuroprotective effect of nitroglycerin in a rodent model of ischemic stroke: evaluation of Bcl-2 expression
    Rosaria Greco
    IRCCS C Mondino Institute of Neurology Foundation, 27100 Pavia, Italy
    Int Rev Neurobiol 82:423-35. 2007
    ....
  12. ncbi request reprint Effects of nimesulide on nitric oxide-induced hyperalgesia in humans--a neurophysiological study
    Giorgio Sandrini
    Psychophysiology of Pain Laboratory, University Center for Adaptive Disorders and Headache, University of Pavia, Via Palestro 3, 27100 Pavia, Italy
    Eur J Pharmacol 450:259-62. 2002
    ..These data suggest a central effect for nimesulide, possibly related to a reduction of nociceptive activity at spinal level...
  13. doi request reprint IkappaB-alpha expression following transient focal cerebral ischemia is modulated by nitric oxide
    Rosaria Greco
    University of Pavia, Pavia, Italy
    Brain Res 1372:145-51. 2011
    ..These findings suggest that NO of neuronal and inducible origin promotes NF-κB activation via IkB-alpha modulation and mediates ischemic-related damage in the brain following ischemia...
  14. doi request reprint Pisa syndrome in Parkinson's disease: clinical, electromyographic, and radiological characterization
    Cristina Tassorelli
    IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    Mov Disord 27:227-35. 2012
    ..This postural abnormality deserves attention and proper early treatment to prevent comorbidities and pain...
  15. doi request reprint Eletriptan
    Giorgio Sandrini
    IRCCS C Mondino Institute of Neurology Foundation, Department of Neurology, Via Mondino 2, Pavia, Italy
    Expert Opin Drug Metab Toxicol 5:1587-98. 2009
    ..Eletriptan showed the most favorable cost-effectiveness profile when compared with other agents in its class...
  16. doi request reprint Deep brain stimulation and cognitive functions in Parkinson's disease: A three-year controlled study
    Roberta Zangaglia
    IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Mov Disord 24:1621-8. 2009
    ....
  17. ncbi request reprint A role for brain cyclooxygenase-2 and prostaglandin-E2 in migraine: effects of nitroglycerin
    Cristina Tassorelli
    IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Int Rev Neurobiol 82:373-82. 2007
    ..This activity may explain the pronociceptive effect of NTG described in animal and human models of pain. Most importantly, these findings point to mediators and areas that may be relevant for migraine pathogenesis and treatment...
  18. pmc www.cefalea.it: the first five years
    Paolo Rossi
    Headache Clinic, INI Grottaferrata, Via S Anna, snc, I 00046, Rome, Italy
    J Headache Pain 6:264-7. 2005
    ..This article summarises the website's first five years of activity and highlights the Internet's potential to improve headache-related decision-making, behaviour and outcomes...
  19. ncbi request reprint Botulinum toxin and neuromotor rehabilitation: An integrated approach to idiopathic cervical dystonia
    Cristina Tassorelli
    Neurorehabilitation Unit, C Mondino Institute of Neurology Foundation, Dept of Neurological Sciences, University of Pavia, Italy
    Mov Disord 21:2240-3. 2006
    ..7 vs. -4.85 points) and subjective pain (-13.35 vs. 6.95 points) scores. Association of BTX-A therapy with a specific program of physical therapy may improve ICD treatment outcome...
  20. doi request reprint Is hemicrania continua a single entity or the association of two headache forms? Considerations from a case report
    Marta Allena
    University Centre for the Study of Adaptive Disorders and Headache, University of Pavia and Headache Centre, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Headache 50:877-81. 2010
    ..The analysis of this case raises interesting issues regarding the proper place of HC among the primary headache forms...
  21. ncbi request reprint Relationship between hallucinations, delusions, and rapid eye movement sleep behavior disorder in Parkinson's disease
    Claudio Pacchetti
    Parkinson s Disease and Movement Disorders Unit, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Mov Disord 20:1439-48. 2005
    ..92), disease duration (OR, 2.46), advanced age (OR, 2.34), and severity of motor symptoms (OR, 2.06). These results suggest that RBD is widely associated with psychosis in PD...
  22. doi request reprint Calcium homeostasis is dysregulated in parkinsonian patients with L-DOPA-induced dyskinesias
    Fabio Blandini
    Laboratory of Functional Neurochemistry, Interdepartmental Research Center for Parkinson s Disease, IRCCS Neurological Institute C Mondino, Pavia, Italy
    Clin Neuropharmacol 32:133-9. 2009
    ..This may represent a distinctive trait of patients prone to develop dyskinetic movements...
  23. ncbi request reprint Unilateral lesion of the subthalamic nucleus enhances cortical fos expression associated with focally evoked seizures in the rat
    Fabio Blandini
    Laboratory of Functional Neurochemistry, IRCCS Neurological Institute C Mondino, Via Mondino, 2, 27100 Pavia, Italy
    Brain Res 1101:145-50. 2006
    ..Abolishing the STN control over the basal ganglia output may therefore play a facilitatory role on cortical activation associated with limbic seizures...
  24. ncbi request reprint REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson's disease
    Elena Sinforiani
    Laboratory of Neuropsychology, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Mov Disord 21:462-6. 2006
    ..The hypothesis that RBD in PD can be considered a risk factor not only of the hallucinations but also of more severe and diffuse cognitive abnormalities needs to be strengthened through a longitudinal evaluation...
  25. pmc From drug-induced headache to medication overuse headache. A short epidemiological review, with a focus on Latin American countries
    Marta Allena
    IRCCS Neurological Institute C Mondino Foundation, University Centre for Headache and Adaptive Disorders, Pavia Section, Via Mondino 2, 27100 Pavia, Italy
    J Headache Pain 10:71-6. 2009
    ..Limited amount of data exists on the burden and impact of MOH in Latin American Countries. In this review, we summarise the reliable information from the literature on the epidemiological impact of MOH...
  26. ncbi request reprint Secondary cervical dystonia in iatrogenic hypoparathyroidism associated with extensive brain calcifications
    Francesca Mancini
    Parkinson s Disease and Movement Disorders Unit, C Mondino Institute of Neurology Foundation, Pavia, Italy
    Funct Neurol 21:165-6. 2006
    ..This case may prove to be, after a review of literature, the first report of CD secondary to iatrogenic hypoparathyroidism in a patient with extensive brain calcifications...
  27. ncbi request reprint Time-course of nigrostriatal damage, basal ganglia metabolic changes and behavioural alterations following intrastriatal injection of 6-hydroxydopamine in the rat: new clues from an old model
    Fabio Blandini
    Laboratory of Functional Neurochemistry, IRCCS Neurological Institute C Mondino, Pavia, Italy
    Eur J Neurosci 25:397-405. 2007
    ....
  28. doi request reprint REM behavior disorder, hallucinations and cognitive impairment in Parkinson's disease: a two-year follow up
    Elena Sinforiani
    Interdepartmental Research Centre for Parkinson s Disease CRIMP, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Mov Disord 23:1441-5. 2008
    ....
  29. pmc A CARE: pathway in medication-overuse headache: the experience of the Headache Centre in Pavia
    Grazia Sances
    Headache Unit, IRCCS, Institute of Neurology C Mondino Foundation, Via Mondino 2, I 27100, Pavia, Italy
    J Headache Pain 6:307-9. 2005
    ....
  30. ncbi request reprint Comparative analysis of the neuronal activation and cardiovascular effects of nitroglycerin, sodium nitroprusside and L-arginine
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, IRCCS Institute of Neurology C Mondino Foundation and University Centre for the Study of Adaptive Disorders and Headache UCADH, Pavia, Italy
    Brain Res 1051:17-24. 2005
    ..Of the NO-related drugs tested in this study, only nitroglycerin confirmed its ability to activate brainstem areas implicated in nociception...
  31. doi request reprint Transplantation of undifferentiated human mesenchymal stem cells protects against 6-hydroxydopamine neurotoxicity in the rat
    Fabio Blandini
    Interdepartmental Research Center for Parkinson s Disease, IRCCS Neurological Institute C Mondino, Pavia, Italy
    Cell Transplant 19:203-17. 2010
    ..The mechanisms underlying this effect remain to be clarified, although it is likely that the acquisition of a glial phenotype by grafted hMSCs may lead to the release of prosurvival cytokines within the lesioned striatum...
  32. pmc Cerebrovascular diseases at the C. Mondino National Institute of Neurology: from Ottorino Rossi to the present day
    Giuseppe Micieli
    IRCCS C Mondino National Institute of Neurology Foundation, Pavia, Italy
    Funct Neurol 26:87-95. 2011
    ....
  33. ncbi request reprint Selective stimulation of striatal dopamine receptors of the D1- or D2-class causes opposite changes of fos expression in the rat cerebral cortex
    Fabio Blandini
    Laboratory of Functional Neurochemistry, IRCCS C Mondino, Pavia, Italy
    Eur J Neurosci 17:763-70. 2003
    ..Our results confirm that striatal D1 dopamine receptors play a central role in the modulation of cortical activity, thus providing additional information on the functional interaction between basal ganglia circuitry and cerebral cortex...
  34. ncbi request reprint Nitroglycerin induces hyperalgesia in rats--a time-course study
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Eur J Pharmacol 464:159-62. 2003
    ..Nitroglycerin induced a significant reduction in the latency of the tail flick 2 and 4 h after its administration. Similarly, formalin-induced pain-related behaviour increased significantly 2 and 4 h after nitroglycerin administration...
  35. ncbi request reprint Cholinesterase inhibitors in Alzheimer's disease: efficacy in a non-selected population
    Elena Sinforiani
    Alzheimer s Disease Assessment Unit and Laboratory of Neuropsychology, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Funct Neurol 18:233-7. 2003
    ..Thereafter, a global cognitive and functional decline was reported, more marked in basic daily activities. No factors (age, sex, disease duration, family history for AD, cognitive impairment at baseline) emerged as predictors of outcome...
  36. ncbi request reprint Double-blind, placebo-controlled study to evaluate the efficacy and safety of botulinum toxin type A in the treatment of drooling in parkinsonism
    Francesca Mancini
    Parkinson s Disease and Movement Disorders Unit, C Mondino Institute of Neurology, IRCCS, Pavia, Italy
    Mov Disord 18:685-8. 2003
    ..No side effects were observed in either group. BTX injection into parotids and submandibular glands, under ultrasonographic guidance, is an effective and safe treatment for drooling in parkinsonism...
  37. ncbi request reprint A questionnaire on sleep and mental disorders in Parkinson's disease (QSMDPD): development and application of a new screening tool
    Claudio Pacchetti
    Parkinson s Disease and Movement Disorders Unit, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Funct Neurol 19:83-99. 2004
    ..This high compliance suggests that the QSMDPD is a promising tool for collecting data on sleep and mental disorders in large samples of PD patients. A short version will be administered as a follow-up tool...
  38. ncbi request reprint Long-term evaluation of the effect of quetiapine on hallucinations, delusions and motor function in advanced Parkinson disease
    Francesca Mancini
    Parkinson s Disease and Movement Disorders Unit, C Mondino Neurological Institute, IRCCS, Pavia, Italy
    Clin Neuropharmacol 27:33-7. 2004
    ....
  39. ncbi request reprint Report of ten years' activity in an Alzheimer's disease assessment unit
    Elena Sinforiani
    Alzheimer s Disease Assessment Unit Laboratory of Neuropsychology, IRCCS C Mondino, Institute of Neurology, Via Mondino 2, 27100 Pavia, Italy
    Aging Clin Exp Res 21:365-8. 2009
    ..After ten years' treatment with cholinesterase inhibitors (AcheI) in Alzheimer's disease (AD), we report here the activity of the Alzheimer's Disease Assessment Unit of IRCCS C. Mondino, Pavia, Italy...
  40. doi request reprint Temporal profile of vascular changes induced by systemic nitroglycerin in the meningeal and cortical districts
    Rosaria Greco
    IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    Cephalalgia 31:190-8. 2011
    ..Systemic nitroglycerin (NTG), a NO donor, is a well-accepted experimental model of migraine. In this study we have examined the effects of NTG on the meningeal and cortical blood flow in rats...
  41. ncbi request reprint Prostaglandins, glutamate and nitric oxide synthase mediate nitroglycerin-induced hyperalgesia in the formalin test
    Cristina Tassorelli
    Laboratory of Pathophysiology of Integrative Autonomic Systems, University Center for the Study of Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Eur J Pharmacol 534:103-7. 2006
    ..The present findings point to the role of prostaglandins, NO synthesis and glutamate activity in the induction of nitroglycerin-induced hyperalgesia...
  42. ncbi request reprint Uncommon primary headaches
    Giorgio Sandrini
    University Center for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Curr Opin Neurol 19:299-304. 2006
    ..The recent classification offers an interesting opportunity to evaluate the clinical role and to discuss the mechanisms of some of the more relevant uncommon primary headaches...
  43. doi request reprint Episodic cluster headache: NREM prevalence of nocturnal attacks. Time to look beyond macrostructural analysis?
    Michele Terzaghi
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Headache 50:1050-4. 2010
    ..A high prevalence of nocturnal sleep-related attacks is reported in patients with cluster headache (CH). Episodic CH is considered closely related to rapid eye movement (REM) sleep...
  44. pmc Almotriptan in the treatment of migraine
    Giorgio Sandrini
    University Centre for Adaptive, Disorders and Headache, IRCCS, C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
    Neuropsychiatr Dis Treat 3:799-809. 2007
    ..On the basis of these findings, almotriptan may be considered a therapeutic option for the acute treatment of migraine attacks...
  45. doi request reprint Use of complementary and alternative medicine by patients with cluster headache: results of a multi-centre headache clinic survey
    Paolo Rossi
    Headache Centre, INI Grottaferrata, Rome, Italy
    Complement Ther Med 16:220-7. 2008
    ..To evaluate the rates, pattern, satisfaction with, and presence of predictors of complementary and alternative medicine (CAM) use in a clinical population of patients with cluster headache (CH)...
  46. ncbi request reprint Different effects of tibolone and low-dose EPT in the management of postmenopausal women with primary headaches
    Rossella E Nappi
    Research Center for Reproductive Medicine, University of Pavia, Pavia, Italy
    Menopause 13:818-25. 2006
    ....
  47. pmc Advice alone versus structured detoxification programmes for complicated medication overuse headache (MOH): a prospective, randomized, open-label trial
    Paolo Rossi
    Headache Clinic, INI Grottaferrata, Via S, Anna s, N, C, 00046, Grottaferrata, Rome, Italy
    J Headache Pain 14:10. 2013
    ....
  48. ncbi request reprint Eletriptan: a review and new perspectives
    Giorgio Sandrini
    University of Pavia, University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Expert Rev Neurother 6:1413-21. 2006
    ..Eletriptan showed the most favorable cost-effectiveness profile when compared with other agents in its class...
  49. doi request reprint Medication-overuse headache and personality: a controlled study by means of the MMPI-2
    Grazia Sances
    Headache Unit, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Headache 50:198-209. 2010
    ....
  50. ncbi request reprint Effects of diffuse noxious inhibitory controls on temporal summation of the RIII reflex in humans
    Mariano Serrao
    Department of Neurology and Otolaryngology, University of Rome La Sapienza, Italy
    Pain 112:353-60. 2004
    ....
  51. doi request reprint The potential protective effect of tramiprosate (homotaurine) against Alzheimer's disease: a review
    Carlo Caltagirone
    University of Roma Tor Vergata, and Scientific Director, IRCSS Santa Lucia Foundation, Rome, Italy
    Aging Clin Exp Res 24:580-7. 2012
    ..In this review, we will examine the pre-clinical and clinical evidence supporting the potential role of homotaurine as a promising candidate for both primary and secondary prevention of AD...
  52. ncbi request reprint Dysphagia in multiple sclerosis: from pathogenesis to diagnosis
    Cristina Tassorelli
    Department of Neurological Sciences, University of Pavia, Via Mondino 2, 27100, Pavia, Italy
    Neurol Sci 29:S360-3. 2008
    ..An integrated approach is proposed to define the severity of dysphagia and to devise the most appropriate therapeutic/rehabilitative methodology...
  53. ncbi request reprint Report of eight new cases of hypnic headache and mini-review of the literature
    Natascia Ghiotto
    Headache Treatment and Diagnosis Centre, University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Funct Neurol 17:211-9. 2002
    ..9% of the cases and unilateral attacks in 36%. Hypnic headache will be included in the fourth chapter (Other Primary Headaches) of the revised edition of the above-mentioned classification (IHC 2nd Edition)...
  54. ncbi request reprint Planning availability in stroke rehabilitation units
    Stefano Paolucci
    IRCCS S Lucia Foundation, Rome, Italy
    Funct Neurol 18:191-4. 2003
    ..Health policies and programming will have to take into account the need for more beds in both types of stroke unit...
  55. pmc Patients with headache and functional dyspepsia present meal-induced hypersensitivity of the stomach
    Ennio Pucci
    University Centre for Adaptive Disorders and Headache UCADH, University of Pavia, IRCCS C Mondino, Via Mondino 2, I 27100 Pavia, Italy
    J Headache Pain 6:223-6. 2005
    ..DTh after meal was lower in dyspeptic headache patients than in HV and dyspeptic without headache patients. Patients with migraine and functional dyspepsia may be characterised by meal-induced hypersensitivity of the stomach...
  56. ncbi request reprint Electrophysiological evidence for trigeminal neuron sensitization in patients with migraine
    Giorgio Sandrini
    Laboratory of Pain Psychophysiology, Department of Neurological Sciences, University Center for Adaptive Disorders and Headache, University of Pavia, Via Palestro 3, 27100 Pavia, Italy
    Neurosci Lett 317:135-8. 2002
    ..These findings suggest that sensorimotor mechanisms and/or pain control systems at the trigeminal level are impaired in migraine. The bilateral location of these abnormalities seems to point to a centrally located dysfunction...
  57. ncbi request reprint Systemic administration of an mGluR5 antagonist, but not unilateral subthalamic lesion, counteracts l-DOPA-induced dyskinesias in a rodent model of Parkinson's disease
    Giovanna Levandis
    Laboratory of Functional Neurochemistry, Interdepartmental Research Center for Parkinsons s Disease CRIMP, IRCCS C Mondino, Pavia, Italy
    Neurobiol Dis 29:161-8. 2008
    ..Our data confirm the role of glutamatergic neurotransmission in the pathogenesis of dyskinesias and the potential of mGluR5 antagonists in the treatment of l-DOPA-induced dyskinesias...
  58. ncbi request reprint Central components of the analgesic/antihyperalgesic effect of nimesulide: studies in animal models of pain and hyperalgesia
    Cristina Tassorelli
    Laboratories of Integrative Autonomic Systems and Neurophysiology of Pain, IRCCS Institute of Neurology C Mondino Foundation, University Center for Adaptive Disorders and Headache, Pavia, Italy
    Drugs 63:9-22. 2003
    ....
  59. ncbi request reprint Activation of the transcription factor NF-kappaB in the nucleus trigeminalis caudalis in an animal model of migraine
    Rosaria Greco
    Laboratory of Pathophysiology of Integrative Autonomic Systems, IRCCS Neurological Institute C Mondino Foundation and University Centre for the Study of Adaptive Disorder and Headache UCADH, Via Palestro 3, 27100 Pavia, Italy
    Neurotoxicology 26:795-800. 2005
    ..Furthermore, these findings pave the way to new bio-molecular and pharmacological avenues for the development of innovative migraine therapies...
  60. ncbi request reprint Prolonged blockade of NMDA or mGluR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease
    Marie Therese Armentero
    Laboratory of Functional Neurochemistry, IRCCS Neurological Institute C Mondino, Via Mondino, 2, 27100 Pavia, Italy
    Neurobiol Dis 22:1-9. 2006
    ..Specific modulation of STN hyperactivity obtained with mGluR5 blockade may, therefore, open interesting perspectives for the use of this class of compounds in the treatment of Parkinson's disease...
  61. ncbi request reprint Peripheral inflammation and neuroprotection: systemic pretreatment with complete Freund's adjuvant reduces 6-hydroxydopamine toxicity in a rodent model of Parkinson's disease
    Marie Therese Armentero
    Laboratory of Functional Neurochemistry, Neurological Institute C Mondino, Via Mondino, 2 27100 Pavia, Italy
    Neurobiol Dis 24:492-505. 2006
    ..Our results show that prior delivery of a peripheral, pro-inflammatory stimulus induces neuroprotection, in a rodent model of Parkinson's disease, possibly through the modulation of cytokine production at the nigrostriatal level...
  62. ncbi request reprint Interaction between Apolipoprotein epsilon 4 and traumatic brain injury in patients with Alzheimer's disease and Mild Cognitive Impairment
    Marco Mauri
    Section of Neurology, Department of Clinical Medicine, Universita dell Insubria, Varese, Italy
    Funct Neurol 21:223-8. 2006
    ..Our data do not suggest that the presence of these two factors influences the clinical presentation or the course of the disease...
  63. ncbi request reprint Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease
    Taku Furuno
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Auerbachstr 112, 70376 Stuttgart, Germany
    Pharmacogenetics 12:529-34. 2002
    ..In conclusion, MDR1 and other drug transporters represent plausible candidates as Parkinson's disease risk genes. Larger studies are required to confirm this role in the etiology of Parkinson's disease...
  64. ncbi request reprint Drug prescribing patterns in Parkinson's disease: a pharmacoepidemiological survey in a cohort of ambulatory patients
    Olivia Leoni
    Center for Research in Clinical and Applied Pharmacology, Laboratory of Pharmacology, University of Insubria and University of Pavia, Varese, Italy
    Pharmacoepidemiol Drug Saf 11:149-57. 2002
    ..Since in IPD there is little information about drug use, this study investigated drug prescribing and indications in IPD patients...
  65. ncbi request reprint Dopaminergic modulation of apoptosis in human peripheral blood mononuclear cells: possible relevance for Parkinson's disease
    Cristina Colombo
    Laboratory of Pharmacology, Faculty of Medicine, University of Insubria, Varese, Italy
    Ann N Y Acad Sci 1010:679-82. 2003
    ..Human PBMCs may thus represent a simple and readily accessible model to study DA-related mechanisms relevant for neurodegenerative disease...
  66. ncbi request reprint Evaluation of thermal water in patients with functional dyspepsia and irritable bowel syndrome accompanying constipation
    Giovanni Gasbarrini
    Department of Internal Medicine, Catholic University of Rome, Italy
    World J Gastroenterol 12:2556-62. 2006
    ..To evaluate the efficacy of water supplementation treatment in patients with functional dyspepsia or irritable bowel syndrome (IBS) accompanying predominant constipation...
  67. ncbi request reprint Neuroendocrine response to the serotonin agonist M-chlorophenylpiperazine in women with menstrual status migrainosus
    Rossella E Nappi
    Department of Obstetric and Gynecology, IRCCS San Matteo, Pavia, Italy
    Neuroendocrinology 78:52-60. 2003
    ....
  68. ncbi request reprint Multicentre Italian family-based association study on tyrosine hydroxylase, catechol-O-methyl transferase and Wolfram syndrome 1 polymorphisms in mood disorders
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, San Raffaele Institute, Milan, Italy
    Psychiatr Genet 13:121-6. 2003
    ..The aim of the present study was to investigate tyrosine hydroxylase, catechol-O-methyl transferase and Wolfram syndrome 1 genes in mood disorders using a family-based association approach...
  69. ncbi request reprint Early and long-term outcome of rehabilitation in stroke patients: the role of patient characteristics, time of initiation, and duration of interventions
    Massimo Musicco
    Institute of Biomedical Technologies, National Research Council, Milan, Italy
    Arch Phys Med Rehabil 84:551-8. 2003
    ..To determine whether and how patient characteristics and the time of initiation and duration of rehabilitation influence early and long-term patient outcome after cerebrovascular accident...
  70. ncbi request reprint Neuronal networks in emotions
    PierFranco Spano
    Funct Neurol 17:111-2. 2002
  71. ncbi request reprint Dopamine receptor agonists mediate neuroprotection in malonate-induced striatal lesion in the rat
    Marie Therese Armentero
    Laboratory of Functional Neurochemistry, IRCCS, C Mondino, Pavia, Italy
    Exp Neurol 178:301-5. 2002
    ..Our data suggest that malonate-induced striatal toxicity can be attenuated by systemic administration of dopamine agonists, with D(1) and D(2) agonists showing different profiles of efficacy...
  72. ncbi request reprint Reproductive life milestones in women with Parkinson's disease
    Emilia Martignoni
    Parkinson s Disease and Movement Disorders Unit, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Funct Neurol 18:211-7. 2003
    ..Our data indicate poor adaptation of neuronal pathways to the hormonal fluctuations of reproductive life in women with PD, supporting the existence of a qualitative relationship between PD and reproductive events...
  73. ncbi request reprint Neuroprotection: promise and pitfalls in anti-inflammatory treatment of Alzheimer's disease
    Maurizio Memo
    Funct Neurol 17:175-6. 2002
  74. ncbi request reprint 5-hydroxytryptamine1B receptor and triptan response in migraine, lack of association with common polymorphisms
    Daniela Velati
    DiSCAFF and DFB Center, Via Bovio, 6, 28100 Novara, Italy
    Eur J Pharmacol 580:43-7. 2008
    ..Our data therefore do not support the involvement of 5-HT(1B) single nucleotide polymorphisms in mediating the inter-individual variability to triptans...
  75. ncbi request reprint Magnetic resonance spectroscopy in Parkinson's disease and parkinsonian syndromes
    Mario Rango
    Department of Neurology, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, Milan, Italy
    Funct Neurol 22:75-9. 2007
    ..MRS is useful for diagnostic purposes, helping to differentiate Parkinson's disease from other parkinsonian syndromes. Even more usefully, MRS can be used for non invasive in vivo human research...
  76. doi request reprint Pain as a nonmotor symptom of Parkinson disease: evidence from a case-control study
    Giovanni Defazio
    Department of Neurology and Psychiatry, University of Bari, Piazza Giulio Cesare 11, I 70124 Bari, Italy
    Arch Neurol 65:1191-4. 2008
    ..To determine whether pain is more frequent among people with Parkinson disease (PD) than among age-matched controls...
  77. ncbi request reprint Cardiovascular dysautonomia as a cause of falls in Parkinson's disease
    Emilia Martignoni
    Unit of Neurorehabilitation and Movement Disorders, IRCCS S Maugeri Foundation, Scientific Institute of Veruno NO and Department of Medical Sciences, University of Piemonte Orientale A Avogadro, Novara, Italy
    Parkinsonism Relat Disord 12:195-204. 2006
    ....
  78. ncbi request reprint Ictal and interictal hypoactivation of the occipital cortex in migraine with aura. A neuroimaging and electrophysiological study
    Placido Bramanti
    Centro Studi Neurolesi, University of Messina, Italy
    Funct Neurol 20:169-71. 2005
    ..Furthermore, the electrophysiological data obtained demonstrated altered activity due to the patient's disease...
  79. pmc Neurophysiological approach to central pain modulation in primary headaches
    Paolo Rossi
    Headache Clinic, INI Grottaferrata, Via S Anna snc, I 00046, Grottaferrata Rome, Italy
    J Headache Pain 6:191-4. 2005
    ..In addition, patients' data will be presented that highlights the utility of such methods for primary headache's pathophysiology and clinical monitoring...
  80. ncbi request reprint Oxidative stress and pro-apoptotic conditions in a rodent model of Wilson's disease
    Alberta Samuele
    Laboratory of Functional Neurochemistry, Neurological Institute C Mondino, Via Mondino, 2 27100 Pavia, Italy
    Biochim Biophys Acta 1741:325-30. 2005
    ..Hence, we assume that enhanced oxidative stress may play a central role in the cell degeneration in WD, at the main sites of copper deposition, with discrete pro-apoptotic conditions developing in distal areas...
  81. ncbi request reprint Migraine with and without aura: electrophysiological and functional neuroimaging evidence
    Placido Bramanti
    Centro Studi Neurolesi, University of Messina, Italy
    Funct Neurol 20:29-32. 2005
    ..The results of this preliminary study need to be confirmed in a a large sample of subjects...
  82. ncbi request reprint Estradiol reduces cytochrome c translocation and minimizes hippocampal damage caused by transient global ischemia in rat
    Giacinto Bagetta
    Department of Pharmacobiology, University of Calabria, Via Pietro Bucci, 87036 Arcavacata di Rende CS, Italy
    Neurosci Lett 368:87-91. 2004
    ....
  83. ncbi request reprint Enhanced anandamide degradation is associated with neuronal apoptosis induced by the HIV-1 coat glycoprotein gp120 in the rat neocortex
    Mauro Maccarrone
    Department of Biomedical Sciences, University of Teramo, Piazza A Moro 45, I 64100 Teramo, Italy
    J Neurochem 89:1293-300. 2004
    ..Taken together, these results suggest that gp120, by activating FAAH, decreases endogenous levels of AEA, and the latter effect seems instrumental in the execution of delayed neuronal apoptosis in the brain neocortex of rats...
  84. ncbi request reprint Family-based association study of 5-HTTLPR, TPH, MAO-A, and DRD4 polymorphisms in mood disorders
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, San Raffaele Institute, Milan, Italy
    Am J Med Genet 114:361-9. 2002
    ..Our study did not support the involvement of 5-HTTLPR, TPH, MAO-A, or DRD4 polymorphisms in mood disorders...