Raffaele Manni

Summary

Affiliation: IRCCS C. Mondino
Country: Italy

Publications

  1. doi Cognitive dysfunction and REM sleep behavior disorder: key findings in the literature and preliminary longitudinal findings
    Raffaele Manni
    Sleep Medicine Unit, C Mondino National Institute of Neurology Foundation, IRCCS, Pavia, Italy Electronic address
    Int J Psychophysiol 89:213-7. 2013
  2. ncbi Sleep disorders in Parkinson's disease: facts and new perspectives
    R Manni
    Sleep Medicine Unit, I R C C S C Mondino Institute of Neurology, Via Mondino 2, I 27100, Pavia, Italy
    Neurol Sci 28:S1-5. 2007
  3. doi Secondary ''incidental'' REM sleep behavior disorder: do we ever think of it?
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, National Institute of Neurology, IRCCS C Mondino Foundation, Via Mondino 2, 27100 Pavia, Italy
    Sleep Med 12:S50-3. 2011
  4. ncbi Rhythmic movements during sleep: a physiological and pathological profile
    R Manni
    Unit of Sleep Medicine and Epilepsy, Institute of Neurology C Mondino Foundation, Via Mondino 2, I 27100 Pavia, Italy
    Neurol Sci 26:s181-5. 2005
  5. ncbi Interictal, potentially misleading, epileptiform EEG abnormalities in REM sleep behavior disorder
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Sleep 29:934-7. 2006
  6. ncbi REM sleep behavior disorder and epileptic phenomena: clinical aspects of the comorbidity
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, Institute of Neurology, C Mondino Foundation, Pavia, Italy
    Epilepsia 47:78-81. 2006
  7. ncbi Rhythmic movements in idiopathic REM sleep behavior disorder
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, Institute of Neurology, IRCCS C Mondino, Pavia, Italy
    Mov Disord 22:1797-800. 2007
  8. ncbi REM sleep behaviour disorder in elderly subjects with epilepsy: frequency and clinical aspects of the comorbidity
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Epilepsy Res 77:128-33. 2007
  9. doi The FLEP scale in diagnosing nocturnal frontal lobe epilepsy, NREM and REM parasomnias: data from a tertiary sleep and epilepsy unit
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, Institute of Neurology, C Mondino Foundation, Pavia, Italy
    Epilepsia 49:1581-5. 2008
  10. pmc Motor-behavioral episodes in REM sleep behavior disorder and phasic events during REM sleep
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, C Mondino Institute of Neurology Foundation, Pavia, Italy
    Sleep 32:241-5. 2009

Detail Information

Publications46

  1. doi Cognitive dysfunction and REM sleep behavior disorder: key findings in the literature and preliminary longitudinal findings
    Raffaele Manni
    Sleep Medicine Unit, C Mondino National Institute of Neurology Foundation, IRCCS, Pavia, Italy Electronic address
    Int J Psychophysiol 89:213-7. 2013
    ..Large cohort studies with more prolonged follow-ups and greater methodological uniformity are needed to provide more reliable and robust findings. ..
  2. ncbi Sleep disorders in Parkinson's disease: facts and new perspectives
    R Manni
    Sleep Medicine Unit, I R C C S C Mondino Institute of Neurology, Via Mondino 2, I 27100, Pavia, Italy
    Neurol Sci 28:S1-5. 2007
    ..As for treatment of sleep disorders, combined pharmacological and non-pharmacological protocols appear to be particularly suitable in their treatment in PD...
  3. doi Secondary ''incidental'' REM sleep behavior disorder: do we ever think of it?
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, National Institute of Neurology, IRCCS C Mondino Foundation, Via Mondino 2, 27100 Pavia, Italy
    Sleep Med 12:S50-3. 2011
    ....
  4. ncbi Rhythmic movements during sleep: a physiological and pathological profile
    R Manni
    Unit of Sleep Medicine and Epilepsy, Institute of Neurology C Mondino Foundation, Via Mondino 2, I 27100 Pavia, Italy
    Neurol Sci 26:s181-5. 2005
    ....
  5. ncbi Interictal, potentially misleading, epileptiform EEG abnormalities in REM sleep behavior disorder
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Sleep 29:934-7. 2006
    ..To examine the implications of interictal epileptiform abnormalities (IEA) in idiopathic REM-sleep behavior disorder (RBD), particularly the risk of misdiagnosing RBD episodes as epileptic nocturnal seizures...
  6. ncbi REM sleep behavior disorder and epileptic phenomena: clinical aspects of the comorbidity
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, Institute of Neurology, C Mondino Foundation, Pavia, Italy
    Epilepsia 47:78-81. 2006
    ..To document the occurrence of REM sleep behavior disorder (RBD) episodes in patients with epilepsy, and of interictal EEG epileptiform abnormalities (IEA) in patients with idiopathic RBD...
  7. ncbi Rhythmic movements in idiopathic REM sleep behavior disorder
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, Institute of Neurology, IRCCS C Mondino, Pavia, Italy
    Mov Disord 22:1797-800. 2007
    ....
  8. ncbi REM sleep behaviour disorder in elderly subjects with epilepsy: frequency and clinical aspects of the comorbidity
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Epilepsy Res 77:128-33. 2007
    ..To evaluate the clinical aspects of REM sleep behaviour disorder (RBD) occurring in elderly people with epilepsy, and the frequency of this comorbidity...
  9. doi The FLEP scale in diagnosing nocturnal frontal lobe epilepsy, NREM and REM parasomnias: data from a tertiary sleep and epilepsy unit
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, Institute of Neurology, C Mondino Foundation, Pavia, Italy
    Epilepsia 49:1581-5. 2008
    ..To test the usefulness of the FLEP scale in diagnosing nocturnal frontal lobe epilepsy (NFLE), arousal parasomnias, and REM sleep behavior disorder (RBD)...
  10. pmc Motor-behavioral episodes in REM sleep behavior disorder and phasic events during REM sleep
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, C Mondino Institute of Neurology Foundation, Pavia, Italy
    Sleep 32:241-5. 2009
    ..To investigate if sudden-onset motor-behavioral episodes in REM sleep behavior disorder (RBD) are associated with phasic events of REM sleep, and to explore the potential meaning of such an association...
  11. ncbi Complex paroxysmal nocturnal behaviors in Parkinson's disease
    Raffaele Manni
    Sleep Unit, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Mov Disord 25:985-90. 2010
    ....
  12. ncbi Comorbidity between epilepsy and sleep disorders
    Raffaele Manni
    Sleep Medicine and Epilepsy Unit, IRCCS C Mondino National Institute of Neurology Foundation, Via Mondino 2, Pavia, Italy
    Epilepsy Res 90:171-7. 2010
    ..Sleep hygiene measures in epilepsy need to be more comprehensive, taking into account the various pathologies that may underlie disordered sleep in epilepsy patients...
  13. doi Hallucinations and REM sleep behaviour disorder in Parkinson's disease: dream imagery intrusions and other hypotheses
    Raffaele Manni
    Unit of Sleep Medicine, IRCCS C Mondino National Institute of Neurology Foundation, Pavia, Italy
    Conscious Cogn 20:1021-6. 2011
    ..Neuropsychological deficits involving visual perception and attentional processes are thought to play an important role in the pathophysiology of VHs. On this basis, RBD in PD could be viewed as a contributory risk factor for VHs...
  14. ncbi The relationship between focal seizures and sleep: an analysis of the cyclic alternating pattern
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Institute of Neurology Foundation, Via Mondino 2, 27100 Pavia, Italy
    Epilepsy Res 67:73-80. 2005
    ..The aim of this study was to examine the relationship between focal epileptic seizures and sleep through analysis of the cyclic alternating pattern (CAP)...
  15. ncbi Obstructive sleep apnea in a clinical series of adult epilepsy patients: frequency and features of the comorbidity
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, C Mondino Institute of Neurology, Pavia, Italy
    Epilepsia 44:836-40. 2003
    ..The aim of this study was to evaluate the rate and features of obstructive sleep apnea (OSA) in adult epilepsy patients...
  16. ncbi Rapid eye movement sleep, non-rapid eye movement sleep, dreams, and hallucinations
    Raffaele Manni
    Istituto Neurologico C Mondino Via Mondino 2, 27100 Pavia, Italy
    Curr Psychiatry Rep 7:196-200. 2005
    ..The role of these processes has been most extensively documented in visual hallucinations occurring in the context of delirium tremens and Parkinson's disease...
  17. ncbi REM behavior disorder associated with epileptic seizures
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, Institute of Neurology, IRCCS C Mondino Foundation, Pavia, Italy
    Neurology 64:883-4. 2005
    ..In each patient, RBD preceded the onset of seizures by several years. The authors hypothesize that REM sleep disruption may facilitate seizure occurrence...
  18. ncbi Rhythmic movement disorder and cyclic alternating pattern during sleep: a video-polysomnographic study in a 9-year-old boy
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Mov Disord 19:1186-90. 2004
    ..We examine the complex interactions between arousal mechanisms and rhythmic movements occurring during sleep...
  19. ncbi Dopamine agonists and sleepiness in PD: review of the literature and personal findings
    Raffaele Manni
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Sleep Med 5:189-93. 2004
    ..This study is aimed at evaluating daytime sleepiness in a series of Parkinson's disease (PD) patients chronically treated with dopamine agonists (DAs) alone or in combination with L-Dopa...
  20. ncbi Hypnic headache: PSG evidence of both REM- and NREM-related attacks
    R Manni
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Foundation, Institute of Neurology, Pavia, Italy
    Neurology 62:1411-3. 2004
    ..In no patient were the HH attacks found to show any close temporal relationship with sleep-related breathing abnormalities...
  21. ncbi Coupling of minor motor events and epileptiform discharges with arousal fluctuations in NFLE
    Michele Terzaghi
    Sleep Medicine and Epilepsy Unit, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Epilepsia 49:670-6. 2008
    ....
  22. ncbi Analysis of video-polysomnographic sleep findings in dementia with Lewy bodies
    Michele Terzaghi
    Sleep Unit, C Mondino National Institute of Neurology Foundation, IRCCS, Pavia, Italy
    Mov Disord 28:1416-23. 2013
    ..We found evidence that a sleep disturbance as the presenting symptom might indicate a different phenotype of the disease, characterized by milder cognitive impairment...
  23. pmc Evidence of dissociated arousal states during NREM parasomnia from an intracerebral neurophysiological study
    Michele Terzaghi
    Sleep Medicine and Epilepsy Unit, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Sleep 32:409-12. 2009
    ..We describe the results of a neurophysiological (intracerebral EEG) investigation that captured an episode of confusional arousal...
  24. doi Dissociated local arousal states underlying essential clinical features of non-rapid eye movement arousal parasomnia: an intracerebral stereo-electroencephalographic study
    Michele Terzaghi
    Sleep Medicine and Epilepsy Unit, IRCCS National Neurological Institute C Mondino Foundation, Pavia, Italy
    J Sleep Res 21:502-6. 2012
    ..The clinical features of the confusional arousals in this patient are highly consistent with a dysfunctional coexistence of local cortical arousal and local cortical sleep...
  25. ncbi REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson's disease
    Elena Sinforiani
    Laboratory of Neuropsychology, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Mov Disord 21:462-6. 2006
    ..The hypothesis that RBD in PD can be considered a risk factor not only of the hallucinations but also of more severe and diffuse cognitive abnormalities needs to be strengthened through a longitudinal evaluation...
  26. doi REM and NREM sleep enactment behaviors in Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies
    Pietro Luca Ratti
    Sleep Unit, IRCCS C Mondino National Institute of Neurology Foundation, Pavia, Italy
    Sleep Med 13:926-32. 2012
    ..We investigated the occurrence and neurobiological significance of abnormal SEBs in the context of PD without cognitive decline compared to PDD/DLB patients...
  27. doi REM behavior disorder, hallucinations and cognitive impairment in Parkinson's disease: a two-year follow up
    Elena Sinforiani
    Interdepartmental Research Centre for Parkinson s Disease CRIMP, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Mov Disord 23:1441-5. 2008
    ....
  28. ncbi Relationship between hallucinations, delusions, and rapid eye movement sleep behavior disorder in Parkinson's disease
    Claudio Pacchetti
    Parkinson s Disease and Movement Disorders Unit, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Mov Disord 20:1439-48. 2005
    ..92), disease duration (OR, 2.46), advanced age (OR, 2.34), and severity of motor symptoms (OR, 2.06). These results suggest that RBD is widely associated with psychosis in PD...
  29. ncbi Cognitive performance in REM sleep behaviour disorder: a possible early marker of neurodegenerative disease?
    Michele Terzaghi
    Sleep Medicine Unit, IRCCS C Mondino Institute of Neurology Foundation, Via Mondino, Pavia, Italy
    Sleep Med 9:343-51. 2008
    ..Researchers are looking for early markers supporting a possible role of RBD as a harbinger of impending neurodegenerative disease...
  30. ncbi Sleep-related minor motor events in nocturnal frontal lobe epilepsy
    Michele Terzaghi
    Sleep Medicine and Epilepsy Unit, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Epilepsia 48:335-41. 2007
    ..Whereas major episodes are considered epileptiform manifestations, it remains unclear whether the MMEs are related to epileptiform discharges (EDs)...
  31. pmc Cognitive performances and mild cognitive impairment in idiopathic rapid eye movement sleep behavior disorder: results of a longitudinal follow-up study
    Michele Terzaghi
    Sleep Medicine Unit, C Mondino National Institute of Neurology Foundation, IRCCS, Pavia, Italy
    Sleep 36:1527-32. 2013
    ..To investigate the capacity of neuropsychological deficits in idiopathic rapid eye movement sleep behavior disorder (iRBD) to predict the development of dementia and/or parkinsonism...
  32. doi Episodic cluster headache: NREM prevalence of nocturnal attacks. Time to look beyond macrostructural analysis?
    Michele Terzaghi
    Unit of Sleep Medicine and Epilepsy, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Headache 50:1050-4. 2010
    ..A high prevalence of nocturnal sleep-related attacks is reported in patients with cluster headache (CH). Episodic CH is considered closely related to rapid eye movement (REM) sleep...
  33. ncbi A questionnaire on sleep and mental disorders in Parkinson's disease (QSMDPD): development and application of a new screening tool
    Claudio Pacchetti
    Parkinson s Disease and Movement Disorders Unit, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Funct Neurol 19:83-99. 2004
    ..This high compliance suggests that the QSMDPD is a promising tool for collecting data on sleep and mental disorders in large samples of PD patients. A short version will be administered as a follow-up tool...
  34. ncbi Memory disturbances and temporal lobe epilepsy simulating Alzheimer's disease: a case report
    Elena Sinforiani
    Alzheimer s Centre, Laboratory of Neuropsychology, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Funct Neurol 18:39-41. 2003
    ..Thus 600 mg/day of carbamazepine was added to donezepil therapy. Antiepileptic treatment completely reversed the cognitive disturbances. Our observation stresses the possibility that unrecognised epilepsy may present as early AD...
  35. doi Migralepsy: a call for a revision of the definition
    Grazia Sances
    Headache Unit, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Epilepsia 50:2487-96. 2009
    ....
  36. ncbi Patients with psychogenic nonepileptic seizures, alone or epilepsy-associated, share a psychological profile distinct from that of epilepsy patients
    Carlo Andrea Galimberti
    Epilepsy Centre, Neurological Institute C Mondino Foundation, Via Palestro 3, 27100 Pavia, Italy
    J Neurol 250:338-46. 2003
    ..However, some differences between ES/PNES and PNES patients were found in the clinical semiology of their PNESs. Our findings could have implications for the diagnosis and for the treatment of patients with PNESs...
  37. doi Sleep paralysis in narcolepsy: more than just a motor dissociative phenomenon?
    Michele Terzaghi
    Unit of Sleep Medicine and Epilepsy, National Institute of Neurology IRCCS C Mondino Foundation, Via Mondino 2, 27100 Pavia, Italy
    Neurol Sci 33:169-72. 2012
    ....
  38. ncbi Hallucinations and sleep-wake cycle in Alzheimer's disease: a questionnaire-based study in 218 patients
    E Sinforiani
    UVA Lab of Neuropsychology, IRCCS C Mondino, Via Mondino 2, I 27100 Pavia, Italy
    Neurol Sci 28:96-9. 2007
    ....
  39. ncbi Evaluation of sleepiness in epilepsy
    R Manni
    Neurologic Institute IRCCS C Mondino, Via Palestro, 3, 27100, Pavia, Italy
    Clin Neurophysiol 111:S111-4. 2000
    ....
  40. ncbi Hallucinations and sleep-wake cycle in PD: a 24-hour continuous polysomnographic study
    R Manni
    Unit of Sleep Medicine, IRCCS C Mondino Institute of Neurology, Pavia, Italy
    Neurology 59:1979-81. 2002
    ..The data reinforce the hypothesis that neural mechanisms implicated in generating sleep and, in particular, in dream imagery play a role in the occurrence of visual hallucinations in PD...
  41. ncbi Sleep disorders and acute nocturnal delirium in the elderly: a comorbidity not to be overlooked
    Michele Terzaghi
    Sleep Medicine and Epilepsy Unit, C Mondino National Neurological Institute, IRCCS, Pavia, Italy Electronic address
    Eur J Intern Med 25:350-5. 2014
    ..Correct diagnosis and optimal treatment of sleep disorders and disrupted sleep can have a significant impact in the elderly, improving sleep quality and reducing the occurrence of abnormal sleep-related behaviours. ..
  42. ncbi Hypersomnia in the Prader Willi syndrome: clinical-electrophysiological features and underlying factors
    R Manni
    Centre of Sleep Medicine, IRCCS Institute of Neurology C. Mondino, Via Palestro 3, 27100, Pavia, Italy
    Clin Neurophysiol 112:800-5. 2001
    ..The potential interacting role of other factors such as subjects age, sex and genetic pattern is suggested and deserve further investigation...
  43. doi Hypnic headache
    Raffaele Manni
    Sleep Medicine and Epilepsy Unit, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
    Handb Clin Neurol 97:469-72. 2010
    ..The co-occurrence of other types of primary headache in the same period or in different periods of life has been reported in about 40% of HH patients...
  44. ncbi Sleep attacks in Parkinson's disease: a clinical and polysomnographic study
    C Pacchetti
    Unit of Parkinson s Disease and Movement Disorders, Institute of Neurology, IRCCS C Mondino Foundation, Pavia, Italy
    Neurol Sci 24:195-6. 2003
    ..The results showed that SAs can be clearly documented through polysomnographic monitoring and really, but rarely, occur in PD. SAs seem to represent the extreme of the continuum of daytime sleepiness observed in PD patients...
  45. ncbi Temporomandibular disorders and sleep disorders: which relationship?
    V Collesano
    Section of Prosthetic Dentistry, Faculty of Medicine and Surgery, University of Pavia, Pavia, Italy
    Minerva Stomatol 53:661-8. 2004
    ....
  46. pmc Multicenter case-control study on restless legs syndrome in multiple sclerosis: the REMS study
    Mauro Manconi
    Sleep Disorders Center, Scientific Institute and Ospedale San Raffaele, Via Stamira d Ancona 20, 20127 Milan, Italy
    Sleep 31:944-52. 2008
    ..To verify the existence of a symptomatic form of restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and to identify possible associated risk factors...