Affiliation: IRCCS Neuromed
Moyanova S, De Fusco A, Santolini I, Celli R, Bucci D, Mastroiacovo F, et al
. Abnormal Hippocampal Melatoninergic System: A Potential Link between Absence Epilepsy and Depression-Like Behavior in WAG/Rij Rats?. Int J Mol Sci. 2018;19: pubmed publisher
Truini A, Piroso S, Pasquale E, Notartomaso S, Di Stefano G, Lattanzi R, et al
. N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans. Mol Pain. 2015;11:14 pubmed publisher
..These data lay the groundwork for investigating the therapeutic potential of NAC in patients with chronic pain. ..
Romanelli P, Fardone E, Bucci D, Battaglia G, BrÃ¤uer Krisch E, Requardt H, et al
. Microradiosurgical cortical transections generated by synchrotron radiation. Phys Med. 2015;31:642-6 pubmed publisher
Busceti C, Di Pietro P, Riozzi B, Traficante A, Biagioni F, NisticÃ² R, et al
. 5-HT(2C) serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice. Pharmacol Res. 2015;99:258-68 pubmed publisher
..Drugs that block 5-HT2C receptors might protect the hippocampus against the detrimental effect of environmental stressors. ..
Battaglia G, Bruno V. Metabotropic glutamate receptor involvement in the pathophysiology of amyotrophic lateral sclerosis: new potential drug targets for therapeutic applications. Curr Opin Pharmacol. 2018;38:65-71 pubmed publisher
Battaglia G, Riozzi B, Bucci D, Di Menna L, Molinaro G, Pallottino S, et al
. Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis. Neurobiol Dis. 2015;74:126-36 pubmed publisher
..LY379268 had no significant effect on the mortality rate of SODG93A. These findings encourage the development of selective mGlu3 receptor agonists/enhancers as neuroprotective agents in ALS. ..
Cannella M, Motolese M, Bucci D, Molinaro G, Gradini R, Bruno V, et al
. Changes in the expression of genes encoding for mGlu4 and mGlu5 receptors and other regulators of the indirect pathway in acute mouse models of drug-induced parkinsonism. Neuropharmacology. 2015;95:50-8 pubmed publisher