- Thyroid hormone deiodinases D1, D2, and D3 are expressed in human endothelial dermal microvascular line: effects of thyroid hormonesLaura Sabatino
Institute of Clinical Physiology, National Research Council CNR, Via Moruzzi 1, 56124, Pisa, Italy
Mol Cell Biochem 399:87-94. 2015..These findings might be of significant clinical relevance, given the important regulatory role of the endothelium as first barrier to the bloodstream. ..
- Development of a new multiplex quantitative real-time PCR assay for the detection of the mtDNA(4977) deletion in coronary artery disease patients: a link with telomere shorteningLaura Sabatino
Institute of Clinical Physiology, National Research Council C N R, 56124 Pisa, Italy
Environ Mol Mutagen 54:299-307. 2013..02 and P = 0.006, respectively). In conclusion, the present study suggests that mtDNA(4977) deletion and telomere shortening may represent additional and synergic major risk factors for the pathogenesis of CAD and its complications...
- Telomere shortening and ionizing radiation: a possible role in vascular dysfunction?Laura Sabatino
Institute of Clinical Physiology, National Research Council C N R, Pisa, Italy
Int J Radiat Biol 88:830-9. 2012..There is also evidence supporting the crucial role of telomeres in the formation of chromosome and chromatid aberrations induced by ionizing radiation...