E Picano

Summary

Affiliation: Institute of Clinical Physiology
Country: Italy

Publications

  1. pmc Transplant of stunned donor hearts rescued by pharmacological stress echocardiography: a "proof of concept" report
    Tonino Bombardini
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Ultrasound 11:27. 2013
  2. pmc The impact of aging and atherosclerotic risk factors on transthoracic coronary flow reserve in subjects with normal coronary angiography
    Maurizio Galderisi
    Division of Cardioangiology, Department of Clinical and Experimental Medicine, Federico II University Hospital, Naples, Italy
    Cardiovasc Ultrasound 10:20. 2012
  3. pmc The true cost of cardiovascular imaging: focusing on downstream, indirect, and environmental costs
    Larissa Braga
    Institute of Clinical Physiology of Pisa, National Council, Via G, Moruzzi, Pisa, Tuscany 1 56124, Italy
    Cardiovasc Ultrasound 11:10. 2013
  4. pmc Cancer and non-cancer brain and eye effects of chronic low-dose ionizing radiation exposure
    Eugenio Picano
    Institute Clinical Physiology of the National Research Council CNR, 56124, Pisa, Italy
    BMC Cancer 12:157. 2012
  5. pmc Abnormal shortened diastolic time length at increasing heart rates in patients with abnormal exercise-induced increase in pulmonary artery pressure
    Tonino Bombardini
    National Research Council, Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Ultrasound 9:36. 2011
  6. pmc The role of cardiovascular magnetic resonance in candidates for Fontan operation: proposal of a new algorithm
    Lamia Ait-Ali
    Institute of Clinical Physiology National Research Council, Ospedale del Cuore G Pasquinucci, Massa, Italy
    J Cardiovasc Magn Reson 13:69. 2011
  7. pmc WEB downloadable software for training in cardiovascular hemodynamics in the (3-D) stress echo lab
    Tonino Bombardini
    Institute of Clinical Physiology, CNR, Pisa, Italy
    Cardiovasc Ultrasound 8:48. 2010
  8. pmc Recruitment of aged donor heart with pharmacological stress echo. A case report
    Giorgio Arpesella
    Department of Surgery and Transplants, Univeresity of Bologna, Italy
    Cardiovasc Ultrasound 4:3. 2006
  9. pmc Post-exercise contractility, diastolic function, and pressure: operator-independent sensor-based intelligent monitoring for heart failure telemedicine
    Tonino Bombardini
    Department of Echocardiography Lab, Institute of Clinical Physiology, National Council of Research, Pisa, Italy
    Cardiovasc Ultrasound 7:21. 2009
  10. pmc Second-opinion stress tele-echocardiography for the Adonhers (Aged donor heart rescue by stress echo) project
    Daniele Franchi
    Department of Echocardiography and Medical Informatics, Institute of Clinical Physiology, National Research Council, Via Moruzzi 1, Pisa 56124, Italy
    Cardiovasc Ultrasound 8:20. 2010

Detail Information

Publications139 found, 100 shown here

  1. pmc Transplant of stunned donor hearts rescued by pharmacological stress echocardiography: a "proof of concept" report
    Tonino Bombardini
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Ultrasound 11:27. 2013
    ..Hearts with regional or global left ventricular dysfunction are excluded from donation, but stress echo might be useful to identify patients with reversible wall motion abnormalities, potentially eligible for donation...
  2. pmc The impact of aging and atherosclerotic risk factors on transthoracic coronary flow reserve in subjects with normal coronary angiography
    Maurizio Galderisi
    Division of Cardioangiology, Department of Clinical and Experimental Medicine, Federico II University Hospital, Naples, Italy
    Cardiovasc Ultrasound 10:20. 2012
    ..CFR is also affected by atherosclerotic risk factors and left ventricular hypertrophy...
  3. pmc The true cost of cardiovascular imaging: focusing on downstream, indirect, and environmental costs
    Larissa Braga
    Institute of Clinical Physiology of Pisa, National Council, Via G, Moruzzi, Pisa, Tuscany 1 56124, Italy
    Cardiovasc Ultrasound 11:10. 2013
    ..Cardiology is the specialty that most will benefit from the outcome as cardiovascular exams represent almost 30% of the total exams acquired annually worldwide...
  4. pmc Cancer and non-cancer brain and eye effects of chronic low-dose ionizing radiation exposure
    Eugenio Picano
    Institute Clinical Physiology of the National Research Council CNR, 56124, Pisa, Italy
    BMC Cancer 12:157. 2012
    ..This assumption has been challenged by recent evidence discussed in the present review...
  5. pmc Abnormal shortened diastolic time length at increasing heart rates in patients with abnormal exercise-induced increase in pulmonary artery pressure
    Tonino Bombardini
    National Research Council, Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Ultrasound 9:36. 2011
    ..The aim of this study was to assess diastolic times at increasing heart rates in normal and in patients with and without abnormal exercise-induced increase in pulmonary artery pressure (PASP)...
  6. pmc The role of cardiovascular magnetic resonance in candidates for Fontan operation: proposal of a new algorithm
    Lamia Ait-Ali
    Institute of Clinical Physiology National Research Council, Ospedale del Cuore G Pasquinucci, Massa, Italy
    J Cardiovasc Magn Reson 13:69. 2011
    ..To propose a new diagnostic algorithm for candidates for Fontan and identify those who can skip cardiac catheterization (CC)...
  7. pmc WEB downloadable software for training in cardiovascular hemodynamics in the (3-D) stress echo lab
    Tonino Bombardini
    Institute of Clinical Physiology, CNR, Pisa, Italy
    Cardiovasc Ultrasound 8:48. 2010
    ..The informatics infrastructure is available on the web, linking to http://cctrainer.ifc.cnr.it...
  8. pmc Recruitment of aged donor heart with pharmacological stress echo. A case report
    Giorgio Arpesella
    Department of Surgery and Transplants, Univeresity of Bologna, Italy
    Cardiovasc Ultrasound 4:3. 2006
    ..A simpler way to screen aged potential donor hearts for initial cardiomyopathy and functionally significant coronary artery disease should be stress echocardiography...
  9. pmc Post-exercise contractility, diastolic function, and pressure: operator-independent sensor-based intelligent monitoring for heart failure telemedicine
    Tonino Bombardini
    Department of Echocardiography Lab, Institute of Clinical Physiology, National Council of Research, Pisa, Italy
    Cardiovasc Ultrasound 7:21. 2009
    ..Recently, a cutaneous force-frequency relation recording system has been validated based on heart sound amplitude and timing variations at increasing heart rates...
  10. pmc Second-opinion stress tele-echocardiography for the Adonhers (Aged donor heart rescue by stress echo) project
    Daniele Franchi
    Department of Echocardiography and Medical Informatics, Institute of Clinical Physiology, National Research Council, Via Moruzzi 1, Pisa 56124, Italy
    Cardiovasc Ultrasound 8:20. 2010
    ..This study aimed to verify feasibility of a "second opinion" of digitally transferred images of stress echo results to minimize technical variability in selection of aged donor hearts for heart transplant...
  11. pmc Arterial pressure changes monitoring with a new precordial noninvasive sensor
    Tonino Bombardini
    Department of Echocardiography Lab, Fondazione Gabriele Monasterio, Italian National Research Council, Pisa, Italy
    Cardiovasc Ultrasound 6:41. 2008
    ..The aim of this study was to assess the relationship between second heart sound amplitude variations at increasing heart rates and hemodynamic changes...
  12. pmc Cardiac functional stress imaging: a sequential approach with stress echo and cardiovascular magnetic resonance
    Rosa Sicari
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Ultrasound 5:47. 2007
    ..CMR might ideally complement SE in well-selected cases with unfeasible and/or ambiguous and/or submaximal results...
  13. pmc Cardiac reflections and natural vibrations: force-frequency relation recording system in the stress echo lab
    Tonino Bombardini
    Department of Echocardiography Echo Lab, IFC, CNR, Pisa, Italy
    Cardiovasc Ultrasound 5:42. 2007
    ..Ideally, the noninvasive, imaging independent, objective assessment of FFR would greatly enhance its practical appeal...
  14. pmc Diastolic time - frequency relation in the stress echo lab: filling timing and flow at different heart rates
    Tonino Bombardini
    Department of Echocardiography, Institute of Clinical Physiology, National Council of Research, Pisa, Italy
    Cardiovasc Ultrasound 6:15. 2008
    ..A cutaneous force-frequency relation recording system based on first heart sound amplitude vibrations has been recently validated. Second heart sound can be simultaneously recorded in order to quantify both systole and diastole duration...
  15. pmc Efficacy of beta-blocker therapy in symptomatic athletes with exercise-induced intra-ventricular gradients
    Carlos Cotrim
    Cardiology Department, Garcia de Orta Hospital, Almada, Portugal
    Cardiovasc Ultrasound 8:38. 2010
    ..The purpose of the present study was to assess the effect of chronic oral β blocker therapy on the occurrence of exercise-induced IVG and mitral valve SAM, in symptomatic athletes...
  16. pmc The impact of carotid plaque presence and morphology on mortality outcome in cardiological patients
    Christina Petersen
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Ultrasound 4:16. 2006
    ..We evaluate both the importance of echographically assessed carotid artery plaque geometry and morphology as predictors of death in hospitalised cardiological patients...
  17. pmc Complications during pharmacological stress echocardiography: a video-case series
    Albert Varga
    2nd Department of Medicine, University of Sciences, Szeged, Hungary
    Cardiovasc Ultrasound 3:25. 2005
    ....
  18. pmc Anniversary editorial: one year of cardiovascular ultrasound
    Eugenio Picano
    Cardiovasc Ultrasound 2:3. 2004
  19. pmc Presumptive myocarditis with ST-Elevation myocardial infarction presentation in young males as a new syndrome. Clinical significance and long term follow up
    Marcello Costantini
    Struttura Complessa di Cardiologia, Ospedale Santa Caterina Novella, Galatina, Italy
    Cardiovasc Ultrasound 9:1. 2011
    ..We describe a case series of presumptive myocarditis with ST segment elevation on admission ECG...
  20. ncbi request reprint Stress echocardiography for the diagnosis of coronary artery disease
    Eugenio Picano
    Istituto di Fisiologia Clinica, CNR, Pisa, Italy
    Indian Heart J 55:223-7. 2003
  21. ncbi request reprint Stress echocardiography
    Eugenio Picano
    Institute of Clinical Physiology, Pisa, CNR, Italy
    Expert Rev Cardiovasc Ther 2:77-88. 2004
    ..In spite of its dependence upon operator's training, it is the best possible choice to achieve the still elusive target of sustainable cardiac imaging in the field of noninvasive diagnosis of coronary artery disease...
  22. ncbi request reprint Stress echocardiography: a historical perspective
    Eugenio Picano
    Institute of Clinical Physiology, Consiglio Nazionale delle Ricerche, Pisa, Italy
    Am J Med 114:126-30. 2003
    ..Because the information provided by stress echocardiography and stress radionuclide perfusion imaging are similar, the choice of test should be made in the context of the environmental, biological, and economic effects of that choice...
  23. pmc Sustainability of medical imaging
    Eugenio Picano
    Consiglio Nazionale delle Ricerche, Institute of Clinical Physiology, Via Moruzzi 1, 56124 Pisa, Italy
    BMJ 328:578-80. 2004
  24. doi request reprint Innate inflammation in myocardial perfusion and its implication for heart failure
    Eugenio Picano
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Ann N Y Acad Sci 1207:107-15. 2010
    ....
  25. pmc The risks of inappropriateness in cardiac imaging
    Eugenio Picano
    Institute of Clinical Physiology, CNR, Pisa, Italy
    Int J Environ Res Public Health 6:1649-64. 2009
    ..Ulysses is tired of useless examinations, exorbitant costs. unaffordable even by the richest society, and unacceptable risks...
  26. ncbi request reprint [Sustainability of medical imaging in cardiology]
    Eugenio Picano
    Responsabile Laboratorio Ecocardiografia dell Istituto di Fisiologia Clinica, CNR, Pisa
    Recenti Prog Med 97:652-62. 2006
    ....
  27. ncbi request reprint Peripheral vascular endothelial function testing for the diagnosis of coronary artery disease
    Zoltan Jambrik
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Am Heart J 148:684-9. 2004
    ..The purpose of the current study was to assess whether endothelium-dependent FMD of the brachial artery, by ultrasound imaging, predicts the presence of angiographically assessed coronary artery disease (CAD)...
  28. pmc Informed consent and communication of risk from radiological and nuclear medicine examinations: how to escape from a communication inferno
    Eugenio Picano
    Institute of Clinical Physiology, National Research Council, Via Moruzzi, 1 56 100, Pisa, Italy
    BMJ 329:849-51. 2004
  29. pmc The diagnostic accuracy of pharmacological stress echocardiography for the assessment of coronary artery disease: a meta-analysis
    Eugenio Picano
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Ultrasound 6:30. 2008
    ..Who is right?..
  30. ncbi request reprint [Risk-benefit balance in cardiovascular imaging: the radiation issue]
    Eugenio Picano
    Istituto di Fisiologia Clinica del CNR, Fondazione Gabriele Monasterio, Pisa
    G Ital Cardiol (Rome) 9:808-14. 2008
    ..By contrast, it is fully acceptable in appropriately selected groups as a filter to more invasive, risky and costly procedures...
  31. ncbi request reprint Noninvasive pacemaker stress echocardiography for diagnosis of coronary artery disease: a multicenter study
    Eugenio Picano
    Institute of Clinical Physiology, Pisa, Italy
    J Am Coll Cardiol 40:1305-10. 2002
    ....
  32. ncbi request reprint Sustainability in the cardiac cath lab
    Eugenio Picano
    CNR, Institute of Clinical Physiology, Via Moruzzi, 1, Pisa 56124, Italy
    Int J Cardiovasc Imaging 23:143-7. 2007
    ..It is recommended by professional guidelines and reinforced by the European law that the responsibility of all physicians is to minimize the radiation injury hazard to their patients, to their professional staff and to themselves...
  33. ncbi request reprint Ultrasound lung comets: a clinically useful sign of extravascular lung water
    Eugenio Picano
    CNR, Institute of Clinical Physiology, Pisa, Italy
    J Am Soc Echocardiogr 19:356-63. 2006
    ..In conclusion, ULCs represent a useful, practical, and appealingly simple way to image directly extravascular lung water...
  34. pmc The American College of Radiology white paper on radiation dose in medicine:deep impact on the practice of cardiovascular imaging
    Eugenio Picano
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Ultrasound 5:37. 2007
    ..Were they be enacted, these simple recommendations would determine a revolution in the contemporary way of teaching, learning and practising cardiology...
  35. ncbi request reprint [Why to publish a scientific paper--or the skill and philosophy of scientific communication]
    Eugenio Picano
    Istituto di Fisiologia Clinica del CNR, Pisa
    Ital Heart J Suppl 6:388-9. 2005
  36. ncbi request reprint Stress echocardiography
    E Picano
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Curr Pharm Des 11:2137-49. 2005
    ....
  37. pmc The radiation issue in cardiology: the time for action is now
    Eugenio Picano
    Institute of Clinical Physiology, CNR, Pisa, Italy
    Cardiovasc Ultrasound 9:35. 2011
    ..A good cardiologist cannot be afraid of life-saving radiation, but must be afraid of radiation unawareness and negligence...
  38. ncbi request reprint Stress echocardiography
    E Picano
    Institute of Clinical Physiology, CNR, Pisa, Italy
    Minerva Cardioangiol 53:195-210. 2005
    ....
  39. ncbi request reprint Prognostic value of pharmacological stress echocardiography in patients with known or suspected coronary artery disease: a prospective, large-scale, multicenter, head-to-head comparison between dipyridamole and dobutamine test. Echo-Persantine Internation
    A Pingitore
    CNR Institute of Clinical Physiology, Pisa, Italy
    J Am Coll Cardiol 34:1769-77. 1999
    ..The study compared the prognostic value of dipyridamole and dobutamine stress echocardiography in patients with known or suspected coronary artery disease...
  40. ncbi request reprint Prognostic value of myocardial viability in medically treated patients with global left ventricular dysfunction early after an acute uncomplicated myocardial infarction: a dobutamine stress echocardiographic study
    E Picano
    From the CNR Institute of Clinical Physiology, Pisa, Italy
    Circulation 98:1078-84. 1998
    ..The aim of this study was to assess the impact on survival of echocardiographically detected viability in medically treated patients with global left ventricular dysfunction evaluated after acute uncomplicated myocardial infarction...
  41. ncbi request reprint Comparison of combination of dipyridamole and dobutamine during echocardiography with thallium scintigraphy with thallium scintigraphy to improve viability detection
    R Sicari
    CNR Institute of Clinical Physiology, Pisa, Italy
    Am J Cardiol 83:6-10. 1999
    ..The specificity of all forms of pharmacologic stress echo is better than thallium-201...
  42. ncbi request reprint The flow-function relationship in patients with chronic coronary artery disease and reduced regional function: a Doppler transesophageal and bidimensional transthoracic echocardiography study
    M Baroni
    CNR Institute of Clinical Physiology, Pisa, Italy
    Int J Card Imaging 15:271-8. 1999
    ..Aim of this study was to determine the flow-function relationship during coronary vasodilatory stress in patients with coronary artery disease and baseline dysfunction...
  43. ncbi request reprint Dipyridamole stress echocardiography
    E Picano
    National Research Council, Institute of Clinical Physiology, Pisa, Italy
    Cardiol Clin 17:481-99, viii. 1999
    ..Multicenter, randomized, prospective, international studies on cost-effectiveness directly comparing a noninvasive strategy centered on stress echo versus an invasive strategy centered on coronary angiography are currently ongoing...
  44. ncbi request reprint Effects of chronic long-term therapy with calcium antagonists on cytogenetic damage in humans
    M G Andreassi
    CNR Institute of Clinical Physiology, Pisa, Italy
    J Hypertens 17:843-6. 1999
    ....
  45. ncbi request reprint The prognostic value of myocardial viability recognized by low dose dipyridamole echocardiography in patients with chronic ischaemic left ventricular dysfunction
    R Sicari
    CNR Institute of Clinical Physiology, Pisa, Italy
    Eur Heart J 22:837-44. 2001
    ..7% vs 86.2, P=ns). CONCLUSION: In severe left ventricular ischaemic dysfunction, myocardial viability, as assessed by low dose dipyridamole echo, is associated with improved survival in revascularized patients...
  46. ncbi request reprint The comparable diagnostic accuracies of dobutamine-stress and dipyridamole-stress echocardiographies: a meta-analysis
    E Picano
    CNR Institute of Clinical Physiology, Pisa, Italy
    Coron Artery Dis 11:151-9. 2000
    ..Dobutamine-stress and dipyridamole-stress echocardiographies are widely used for pharmacological stress echocardiography, with wide geographical variations...
  47. ncbi request reprint Antioxidant effect of oral dipyridamole during cerebral hypoperfusion with human carotid endarterectomy
    C Kusmic
    Institute of Clinical Physiology, CNR, Pisa, Italy
    J Cardiovasc Pharmacol 36:141-5. 2000
    ..u.; clamp, 352+/-9 a.u.; p < 0.01 vs. rest; declamp, 343+/-6 a.u.; p < 0.05 vs. rest). Cerebral oxidative stress associated with human carotid endarterectomy can be attenuated by pretreatment with oral dipyridamole...
  48. ncbi request reprint Glucose-insulin-potassium treatment in combination with dipyridamole inhibits ischaemia-reperfusion-induced damage
    S Bertuglia
    CNR Institute of Clinical Physiology, Medical School, University of Pisa, Pisa, Italy
    Diabetologia 44:2165-70. 2001
    ..We therefore investigated the microcirculatory changes following I/R after glucose-insulin-potassium or in association with glucose-insulin-potassium dipyridamole in hamster cheek pouch...
  49. ncbi request reprint Safety, feasibility, and diagnostic accuracy of accelerated high-dose dipyridamole stress echocardiography
    R Dal Porto
    Institute of Clinical Physiology, Pisa, Italy
    Am J Cardiol 87:520-4. 2001
    ..This protocol is especially appealing for its excellent diagnostic accuracy coupled with the short imaging time and no need for drug cocktails...
  50. ncbi request reprint Clinical and functional determinants of coronary flow reserve in non-ischemic dilated cardiomyopathy: an echocardiographic study
    Patricia Santagata
    CNR, Institute of Clinical Physiology, Via Moruzzi 1, 56124 Pisa, Italy
    Int J Cardiol 105:46-52. 2005
    ..The clinical functional class is the strongest predictor of CFR reduction in these patients, with lowest flow reserve found in more advanced NYHA class...
  51. ncbi request reprint Prognostic value of pharmacologic stress echocardiography in patients with idiopathic dilated cardiomyopathy: a prospective, head-to-head comparison between dipyridamole and dobutamine test
    Lorenza Pratali
    National Council of Research, Institute of Clinical Physiology, Pisa, Italy
    J Card Fail 13:836-42. 2007
    ..The purpose of the present study was to assess the relative prognostic value of dobutamine versus dipyridamole stress echocardiography for the prediction of all-cause death in patients with idiopathic DCM...
  52. doi request reprint Radioprotection (un)awareness in cardiologists, and how to improve it
    C Carpeggiani
    CNR, Institute of Clinical Physiology, Via Moruzzi, 1, 56124 Pisa, Italy
    Int J Cardiovasc Imaging 28:1369-74. 2012
    ..Awareness of radiological doses and risks, albeit essential for risk-benefit assessment of radiological testing, is suboptimal among cardiologists, but can dramatically improve with a limited teaching effort through targeted training...
  53. ncbi request reprint Pharmacologic stress echocardiography in the assessment of coronary artery disease
    E Picano
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Curr Opin Cardiol 14:464-70. 1999
    ....
  54. ncbi request reprint Diagnosis of myocardial ischemia in hypertensive patients
    E Picano
    Istituto di Fisiologia Clinica, CNR, Pisa, Italy
    J Hypertens 19:1177-83. 2001
    ....
  55. ncbi request reprint Perioperative prognostic value of dipyridamole echocardiography in vascular surgery: A large-scale multicenter study in 509 patients. EPIC (Echo Persantine International Cooperative) Study Group
    R Sicari
    CNR Institute of Clinical Physiology, Pisa, Italy
    Circulation 100:II269-74. 1999
    ..The aim of the current study was to evaluate the value of dipyridamole echocardiography test (up to 0.84 mg/kg over 10 minutes) in predicting cardiac events in a large-scale, multicenter, prospective, observational study design...
  56. ncbi request reprint Chronic oral dipyridamole as a 'novel' antianginal drug: the collateral hypothesis
    E Picano
    CNR Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Res 33:666-70. 1997
    ..Prospective, properly designed trials are needed to assess convincingly the efficacy of a drug used for 40 years and yet possibly prematurely discarded as an effective antianginal treatment...
  57. ncbi request reprint New technologies in stress echocardiography
    E Picano
    Institute of Clinical Physiology, CNR, Pisa, Italy
    Rev Port Cardiol 20:I27-32. 2001
    ..However, cardiologists have to be aware that due the pro-technology bias of modern medicine, we, as physicians, are encouraged to trust, to use (and to buy) technologies far before their clinical incremental value has been shown...
  58. ncbi request reprint The antioxidant drug dipyridamole spares the vitamin E and thiols in red blood cells after oxidative stress
    C Kusmic
    Institute of Clinical Physiology, CNR, Via Savi, 8 56126, Pisa, Italy
    Cardiovasc Res 47:510-4. 2000
    ....
  59. ncbi request reprint Reproductive effects of low-to-moderate medical radiation exposure
    G Latini
    CNR, Institute of Clinical Physiology, Italy
    Curr Med Chem 19:6171-7. 2012
    ..h., reproductive hormone balance, sperm quality, sperm DNA damage) might be more fruitful in future research focused in the low-to-moderate dose range (< 1000 mSv) of greatest interest for diagnostic and professional exposures...
  60. ncbi request reprint Prognostic significance of the dobutamine echocardiography test in idiopathic dilated cardiomyopathy
    L Pratali
    C.N.R. Institute of Clinical Physiology, Pisa, Italy
    Am J Cardiol 88:1374-8. 2001
    ..6% vs 69.4%, p = 0.00033). Thus, in patients with IDC, an extensive contractile reserve identified by high-dose dobutamine stress echocardiography is associated with a better survival...
  61. ncbi request reprint Blunted increase in plasma adenosine levels following dipyridamole stress in dilated cardiomyopathy patients
    F Laghi-Pasini
    Institute of Clinical Physiology of Consiglio Nazionale delle Ricerche, Pisa, Italy
    J Intern Med 254:591-6. 2003
    ....
  62. ncbi request reprint Regional concordance and discordance between rest thallium 201 and sestamibi imaging for assessing tissue viability: comparison with postrevascularization functional recovery
    P Marzullo
    National Research Council Institute of Clinical Physiology, Pisa, Italy
    J Nucl Cardiol 2:309-16. 1995
    ..Whether the combined analysis of rest 201Tl and sestamibi uptake provides additional information regarding myocardial viability in patients with coronary artery disease is still to be investigated...
  63. ncbi request reprint The alternative "ischemic" cascade in coronary microvascular disease
    E Picano
    Istituto di Fisiologia Clinica del CNR, Pisa
    Cardiologia 44:791-5. 1999
    ..quot;Anatomic lies" on the ECG may be overturned into "physiologic truths" when coronary flow reserve or systemic endothelial function is considered...
  64. ncbi request reprint Effect of coronary bypass and cardiac valve surgery on systemic endothelial function
    M Morelos
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Am J Cardiol 87:364-6, A10. 2001
    ....
  65. ncbi request reprint Aortic valve sclerosis is associated with systemic endothelial dysfunction
    Elisa Poggianti
    Echocardiography Laboratory, Institute of Clinical Physiology, CNR, Pisa, Italy
    J Am Coll Cardiol 41:136-41. 2003
    ..We sought to examine the association between aortic valve sclerosis (AVS) and systemic endothelial manifestations of the atherosclerotic process...
  66. ncbi request reprint Force-frequency relationship in the echocardiography laboratory: a noninvasive assessment of Bowditch treppe?
    Tonino Bombardini
    Institute of Clinical Physiology, Via Moruzzi I, 56124 Pisa, Italy
    J Am Soc Echocardiogr 16:646-55. 2003
    ..Estimation of contractility of the left ventricle is an important, and as yet elusive, goal with noninvasive techniques...
  67. ncbi request reprint Noninvasive assessment of left ventricular contractility by pacemaker stress echocardiography
    Tonino Bombardini
    CNR, Institute of Clinical Physiology, Via Moruzzi 1, 56124 Pisa, Italy
    Eur J Heart Fail 7:173-81. 2005
    ..An increased heart rate progressively increases the force of ventricular contraction (Bowditch treppe or staircase phenomenon)...
  68. ncbi request reprint Exercise-electrocardiography and/or pharmacological stress echocardiography for non-invasive risk stratification early after uncomplicated myocardial infarction. A prospective international large scale multicentre study
    R Sicari
    CNR Institute of Clinical Physiology, Pisa, Italy
    Eur Heart J 23:1030-7. 2002
    ....
  69. doi request reprint Excimer laser in acute myocardial infarction: single centre experience on 66 patients
    V Ambrosini
    CNR, Institute of Clinical Physiology, Pisa, Italy Clinica Cardiologica Montevergine, Mercogliano, Italy
    Int J Cardiol 127:98-102. 2008
    ..Pulsed-wave ultraviolet excimer laser light at 308 nm can vaporise thrombus, suppress platelet aggregation, and, unlike other thrombectomy devices, ablates the underlying plaque...
  70. ncbi request reprint Safety of ergot stress echocardiography for non-invasive detection of coronary vasospasm
    A Palinkas
    Institute of Clinical Physiology, Consiglio Nazionale Ricerche, Pisa, Italy
    Coron Artery Dis 12:649-54. 2001
    ..The safety of ergonovine/ergometrine stress testing for coronary vasospasm when performed outside the cardiac catheterization laboratory (cath lab) has been questioned vigorously...
  71. ncbi request reprint Early detection of acute lung injury uncoupled to hypoxemia in pigs using ultrasound lung comets
    Luna Gargani
    Institute of Clinical Physiology, National Research Council, Pisa, Italy
    Crit Care Med 35:2769-74. 2007
    ....
  72. ncbi request reprint Acute chromosomal DNA damage in human lymphocytes after radiation exposure in invasive cardiovascular procedures
    Maria Grazia Andreassi
    CNR Institute of Clinical Physiology, G Pasquinucci Hospital, Via Aurelia Sud Montepepe, 54100 Massa, Italy
    Eur Heart J 28:2195-9. 2007
    ..We evaluated whether radiation exposure during interventional cardiovascular procedures can induce damage to deoxyribonucleic acid (DNA)...
  73. ncbi request reprint Prognostic value of extravascular lung water assessed with ultrasound lung comets by chest sonography in patients with dyspnea and/or chest pain
    Francesca Frassi
    Consiglio Nazionale delle Ricerche, Institute of Clinical Physiology, Pisa, Italy
    J Card Fail 13:830-5. 2007
    ..The objective was to assess the prognostic value of ULCs in patients with dyspnea and/or chest pain syndrome at hospital admission...
  74. doi request reprint Ultrasound lung comets in systemic sclerosis: a chest sonography hallmark of pulmonary interstitial fibrosis
    Luna Gargani
    Institute of Clinical Physiology, National Research Council, Via G Moruzzi, 1, 56124, Pisa, Italy
    Rheumatology (Oxford) 48:1382-7. 2009
    ....
  75. doi request reprint Additive prognostic value of coronary flow reserve in patients with chest pain syndrome and normal or near-normal coronary arteries
    Rosa Sicari
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Am J Cardiol 103:626-31. 2009
    ....
  76. doi request reprint Transthoracic sensor for noninvasive assessment of left ventricular contractility: validation in a minipig model of chronic heart failure
    Vincenzo Gemignani
    National Research Council, Institute of Clinical Physiology, Pisa, Italy
    Pacing Clin Electrophysiol 33:795-803. 2010
    ..Comparative assessment was performed both at rest and following dobutamine infusion...
  77. doi request reprint A new simple method to estimate pulmonary regurgitation by echocardiography in operated fallot: comparison with magnetic resonance imaging and performance test evaluation
    Pierluigi Festa
    Pediatric Cardiology, Ospedale del Cuore, CNR Reg Toscana Fondazione Gabriele Monasterio, Massa Pisa, Italy
    J Am Soc Echocardiogr 23:496-503. 2010
    ..The aim of this study was to assess a novel transthoracic echocardiographic method to estimate the severity of pulmonary regurgitation (PR) in patients with surgically repaired tetralogy of Fallot...
  78. doi request reprint The prognostic value of Doppler echocardiographic-derived coronary flow reserve is not affected by concomitant antiischemic therapy at the time of testing
    Rosa Sicari
    National Council of Research, Institute of Clinical Physiology, Pisa, Italy
    Am Heart J 156:573-9. 2008
    ..The aim of the study was to determine whether antianginal medications affect the prognostic value of Doppler echocardiographic-derived CFR in patients with known or suspected coronary artery disease undergoing DET...
  79. doi request reprint Frequent subclinical high-altitude pulmonary edema detected by chest sonography as ultrasound lung comets in recreational climbers
    Lorenza Pratali
    Institute of Clinical Physiology, CNR, Pisa, Italy
    Crit Care Med 38:1818-23. 2010
    ..The aim of this study was to evaluate, by chest sonography, the incidence of interstitial pulmonary edema in recreational high-altitude climbers...
  80. ncbi request reprint Head to head comparison between perfusion and function during accelerated high-dose dipyridamole magnetic resonance stress for the detection of coronary artery disease
    Alessandro Pingitore
    Clinical Physiology Institute, Consiglio Nazionale delle Ricerche, Pisa, Italy
    Am J Cardiol 101:8-14. 2008
    ....
  81. doi request reprint Genetic polymorphisms in XRCC1, OGG1, APE1 and XRCC3 DNA repair genes, ionizing radiation exposure and chromosomal DNA damage in interventional cardiologists
    Maria Grazia Andreassi
    CNR Institute of Clinical Physiology, National Research Council, Pisa, Italy
    Mutat Res 666:57-63. 2009
    ..3, p=0.02). XRCC3 241Met alleles, particularly in combination with multiple risk alleles of DNA repair genes, contribute to chromosomal DNA damage levels in interventional cardiologists...
  82. ncbi request reprint Cardiac imaging: the biological effects of diagnostic cardiac ultrasound
    Maria Grazia Andreassi
    CNR Institute of Clinical Physiology, Pisa, Italy
    Prog Biophys Mol Biol 93:399-410. 2007
    ....
  83. ncbi request reprint The additive prognostic value of restrictive pattern and dipyridamole-induced contractile reserve in idiopathic dilated cardiomyopathy
    Lorenza Pratali
    Institute of Clinical Physiology, CNR, Via G Moruzzi no 1, Pisa 56124, Italy
    Eur J Heart Fail 7:844-51. 2005
    ..Diastolic dysfunction and lack of contractile reserve are unfavorable prognostic predictors in patients with dilated cardiomyopathy (DCM)...
  84. ncbi request reprint Prognostic value of pharmacological stress echocardiography is affected by concomitant antiischemic therapy at the time of testing
    Rosa Sicari
    CNR Institute of Clinical Physiology, Via G Moruzzi, 1, 561200 Pisa, Italy
    Circulation 109:2428-31. 2004
    ..The aim of this study was to determine whether antianginal medications affect the prognostic value of pharmacological stress echocardiography...
  85. ncbi request reprint Long-term survival of patients with chest pain syndrome and angiographically normal or near-normal coronary arteries: the additional prognostic value of dipyridamole echocardiography test (DET)
    Rosa Sicari
    CNR, Institute of Clinical Physiology, Via G Moruzzi 1, 56123 Pisa, Italy
    Eur Heart J 26:2136-41. 2005
    ..Patients with normal coronary arteries have a heterogeneous prognosis. Aim of this study was to assess whether dipyridamole stress echocardiography positivity identifies a prognostically less benign subset...
  86. ncbi request reprint In vitro modulation of intracellular oxidative stress of endothelial cells by diagnostic cardiac ultrasound
    Giuseppina Basta
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Cardiovasc Res 58:156-61. 2003
    ..Free radical production in the extracellular medium is the likely mediator of ultrasound effect...
  87. ncbi request reprint Pharmacologic stress echocardiography predicts total mortality early after acute myocardial infarction
    Rosa Sicari
    Institute of Clinical Physiology, CNR, Via Giuseppi Moruzzi 1, 56123 Pisa, Italy
    J Am Soc Echocardiogr 17:114-20. 2004
    ..The aim of this multicenter, prospective, observational study was to assess the value of inducible ischemia in a large population of survivors of a first uncomplicated myocardial infarction (MI)...
  88. ncbi request reprint AMPD1 (C34T) polymorphism and clinical outcomes in patients undergoing myocardial revascularization
    Maria Grazia Andreassi
    Institute of Clinical Physiology, Pisa, Italy
    Int J Cardiol 101:191-5. 2005
    ..C34T variant of adenosine monophosphate deaminase 1 (AMPD1) gene has been associated with a prolonged survival in heart failure and coronary artery disease, hypothetically linked to an enhanced production of adenosine...
  89. ncbi request reprint Somatic DNA damage in interventional cardiologists: a case-control study
    Maria Grazia Andreassi
    Institute of Clinical Physiology CNR, Pisa, Italy
    FASEB J 19:998-9. 2005
    ....
  90. ncbi request reprint Diabetes and chronic nitrate therapy as co-determinants of somatic DNA damage in patients with coronary artery disease
    Maria Grazia Andreassi
    CNR Institute of Clinical Physiology, Pisa, Italy
    J Mol Med (Berl) 83:279-86. 2005
    ..DNA damage might represent an additional pathogenetic dimension and a possible therapeutic target in the still challenging management of coronary artery disease concerning diabetics...
  91. ncbi request reprint Principle of responsibility in medical imaging
    Anna Suhova
    Scuola Superiore Sant Anna, Universita degli Studi, Pisa, Italy
    Ann Ist Super Sanita 39:205-12. 2003
    ....
  92. ncbi request reprint Prognostic value of myocardial viability recognized by low-dose dobutamine echocardiography in chronic ischemic left ventricular dysfunction
    Rosa Sicari
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Am J Cardiol 92:1263-6. 2003
    ..1% vs 62%, p <0.0078). Thus, in severe LV ischemic dysfunction, myocardial viability by low-dose dobutamine echocardiography is associated with improved survival in revascularized patients...
  93. ncbi request reprint Stress echo results predict mortality: a large-scale multicenter prospective international study
    Rosa Sicari
    National Council of Research, Institute of Clinical Physiology, Via G Moruzzi 1, 56125 Pisa, Italy
    J Am Coll Cardiol 41:589-95. 2003
    ....
  94. ncbi request reprint Cardiac catheterization and long-term chromosomal damage in children with congenital heart disease
    Maria Grazia Andreassi
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Eur Heart J 27:2703-8. 2006
    ..Chromosomal aberrations test (CA) and micronucleus assay (MN) in peripheral blood lymphocytes are biomarkers of chromosomal damage and intermediate endpoints in carcinogenesis...
  95. ncbi request reprint Long-term prognostic value of dipyridamole echocardiography in vascular surgery: a large-scale multicenter study
    Rosa Sicari
    Institute of Clinical Physiology, Via G Moruzzi, Pisa
    Coron Artery Dis 13:49-55. 2002
    ..The aim of the present study was to assess the value of a preoperative dipyridamole echocardiography test (up to 0.84 mg/kg over 10 min) in predicting late cardiac events in survivors of major non-cardiac vascular surgery...
  96. doi request reprint The association of micronucleus frequency with obesity, diabetes and cardiovascular disease
    Maria Grazia Andreassi
    GENETICS RESEARCH UNIT, Institute of Clinical Physiology, Italian National Research Council, Via Moruzzi 1, 56126 Pisa, Italy
    Mutagenesis 26:77-83. 2011
    ..Large population-based cohorts are needed in order to compare the MN frequencies as well as to better define whether MN is a biomarker or a mediator of cardiometabolic diseases...
  97. ncbi request reprint Stress-induced changes in subendocardial tissue texture in hypertrophic cardiomyopathy: an echocardiographic videodensitometric study
    A Pingitore
    Institute of Clinical Physiology, CNR, Pisa, Italy
    Int J Cardiovasc Imaging 17:245-52. 2001
    ..Stress-induced subendocardial underperfusion has been demonstrated in patients with hypertrophic cardiomyopathy (HCM)...
  98. ncbi request reprint Ultrasound lung comets for the differential diagnosis of acute cardiogenic dyspnoea: a comparison with natriuretic peptides
    L Gargani
    Institute of Clinical Physiology, National Research Council, Pisa, Italy
    Eur J Heart Fail 10:70-7. 2008
    ..Natriuretic peptides have been shown to be useful in this setting. Ultrasound lung comets (ULCs) are a simple, echographic method which can be used to assess pulmonary congestion...
  99. ncbi request reprint Effects of diagnostic cardiac ultrasound on oxygen free radical production and microvascular perfusion during ischemia reperfusion
    S Bertuglia
    CNR Institute of Clinical Physiology, Faculty of Medicine, University of Pisa, Pisa, Italy
    Ultrasound Med Biol 30:549-57. 2004
    ..Moreover, US enhanced wall shear stress and reduced oxidative stress during postischemic reperfusion; thus, increasing capillary perfusion...
  100. ncbi request reprint Head-to-head comparison of dipyridamole echocardiography and stress perfusion scintigraphy for the detection of coronary artery disease: a meta-analysis. Comparison between stress echo and scintigraphy
    Muhammad B Imran
    CNR, Institute of Clinical Physiology, Pisa, Italy
    Int J Cardiovasc Imaging 19:23-8. 2003
    ..This meta-analysis was performed to assess and compare the diagnostic accuracy of dipyridamole echocardiography test (DET) vs. stress perfusion scintigraphy (SPS) for the diagnosis of coronary artery disease (CAD)...
  101. doi request reprint Cancer risk from professional exposure in staff working in cardiac catheterization laboratory: insights from the National Research Council's Biological Effects of Ionizing Radiation VII Report
    Lucia Venneri
    CNR, Institute of Clinical Physiology and Fondazione Gabriele Monasterio, Pisa, Italy
    Am Heart J 157:118-24. 2009
    ..The aim of the present study was to evaluate the order of magnitude of cancer risk caused by professional radiation exposure in modern invasive cardiology practice...