R Caprilli

Summary

Affiliation: Institute of Infectious Diseases and Public Health
Country: Italy

Publications

  1. doi request reprint Eating the enemy in Crohn's disease: an old theory revisited
    Renzo Caprilli
    University of Rome La Sapienza, Rome, Italy
    J Crohns Colitis 4:377-83. 2010
  2. doi request reprint Advances in the pathogenesis of inflammatory bowel diseases: Capri 2010
    Renzo Caprilli
    University of Rome, La Sapienza, Rome, Italy
    Expert Rev Clin Immunol 6:527-30. 2010
  3. doi request reprint The dyspeptic macrophage 30 years later: an update in the pathogenesis of Crohn's disease
    R Caprilli
    University of Rome La Sapienza, Via di Novella, 11, 00199 Rome, Italy
    Dig Liver Dis 41:166-8. 2009
  4. doi request reprint Recent advances in the management of Crohn's disease
    R Caprilli
    University of Rome La Sapienza, Rome, Italy
    Dig Liver Dis 40:709-16. 2008
  5. ncbi request reprint Appropriateness of immunosuppressive drugs in inflammatory bowel diseases assessed by RAND method: Italian Group for IBD (IG-IBD) position statement
    R Caprilli
    Promoter Centre, GI Unit, Department of Clinical Science, University of Rome La Sapienza, Viale del Policlinico 155, 00161 Rome, Italy
    Dig Liver Dis 37:407-17. 2005
  6. ncbi request reprint Mucosal features and granulocyte-monocyte-apheresis in steroid-dependent/refractory ulcerative colitis
    V D'Ovidio
    Department of Clinical Sciences, GI Unit, Policlinico Umberto I, University of Rome, La Sapienza, Viale del Policlinico 155, Rome, Italy
    Dig Liver Dis 38:389-94. 2006
  7. ncbi request reprint Seasonal variations in onset of symptoms in Crohn's disease
    A Aratari
    Department of Clinical Sciences, University La Sapienza, Rome, Italy
    Dig Liver Dis 38:319-23. 2006
  8. ncbi request reprint Early versus late surgery for ileo-caecal Crohn's disease
    A Aratari
    Gastroenterology Unit, Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Aliment Pharmacol Ther 26:1303-12. 2007
  9. doi request reprint Colectomy rate in acute severe ulcerative colitis in the infliximab era
    A Aratari
    Gastroenterology Unit, Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Dig Liver Dis 40:821-6. 2008
  10. ncbi request reprint Infliximab in refractory pouchitis complicated by fistulae following ileo-anal pouch for ulcerative colitis
    A Viscido
    GI Unit, Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Aliment Pharmacol Ther 17:1263-71. 2003

Detail Information

Publications33

  1. doi request reprint Eating the enemy in Crohn's disease: an old theory revisited
    Renzo Caprilli
    University of Rome La Sapienza, Rome, Italy
    J Crohns Colitis 4:377-83. 2010
    ..Thus, the induction of autophagy or administration of preparations that mirrors the secretion of Paneth cells or both may be regarded as new therapeutic avenues for the treatment of Crohn's disease...
  2. doi request reprint Advances in the pathogenesis of inflammatory bowel diseases: Capri 2010
    Renzo Caprilli
    University of Rome, La Sapienza, Rome, Italy
    Expert Rev Clin Immunol 6:527-30. 2010
    ..The structure of the meeting consisted of eight sessions covering selected basic aspects of inflammatory bowel disease, and were designed to be very interactive and more focused on basic science than purely clinical aspects...
  3. doi request reprint The dyspeptic macrophage 30 years later: an update in the pathogenesis of Crohn's disease
    R Caprilli
    University of Rome La Sapienza, Via di Novella, 11, 00199 Rome, Italy
    Dig Liver Dis 41:166-8. 2009
    ..Defective autophagy and dyspeptic macrophages seems therefore indicate the same pathogenetic mechanism. What is really new is the demonstration that this impaired macrophage function is genetically determined...
  4. doi request reprint Recent advances in the management of Crohn's disease
    R Caprilli
    University of Rome La Sapienza, Rome, Italy
    Dig Liver Dis 40:709-16. 2008
    ..Surgery remains a valid resort for refractory patients. Autologous stem cell transplantation represents a new hope as rescue treatment for patients with severe refractory Crohn's disease...
  5. ncbi request reprint Appropriateness of immunosuppressive drugs in inflammatory bowel diseases assessed by RAND method: Italian Group for IBD (IG-IBD) position statement
    R Caprilli
    Promoter Centre, GI Unit, Department of Clinical Science, University of Rome La Sapienza, Viale del Policlinico 155, 00161 Rome, Italy
    Dig Liver Dis 37:407-17. 2005
    ..Despite the explosion of biological therapies, the old immunosuppressants continue to play a pivotal role in the management of inflammatory bowel diseases...
  6. ncbi request reprint Mucosal features and granulocyte-monocyte-apheresis in steroid-dependent/refractory ulcerative colitis
    V D'Ovidio
    Department of Clinical Sciences, GI Unit, Policlinico Umberto I, University of Rome, La Sapienza, Viale del Policlinico 155, Rome, Italy
    Dig Liver Dis 38:389-94. 2006
    ..While several studies have stressed the efficacy of granulocyte-monocyte-apheresis in inducing clinical remission in active ulcerative colitis, few data are available on mucosal features...
  7. ncbi request reprint Seasonal variations in onset of symptoms in Crohn's disease
    A Aratari
    Department of Clinical Sciences, University La Sapienza, Rome, Italy
    Dig Liver Dis 38:319-23. 2006
    ..Seasonal variations in onset of symptoms have been reported in ulcerative colitis but not in Crohn's disease. AIM.: To investigate whether our inflammatory bowel diseases patients presented seasonal variations in onset of symptoms...
  8. ncbi request reprint Early versus late surgery for ileo-caecal Crohn's disease
    A Aratari
    Gastroenterology Unit, Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Aliment Pharmacol Ther 26:1303-12. 2007
    ..Surgery is usually performed for refractory or complicated disease: no studies appear to have been carried out, so far, to evaluate the potential benefits of performing surgery early in the course of the disease...
  9. doi request reprint Colectomy rate in acute severe ulcerative colitis in the infliximab era
    A Aratari
    Gastroenterology Unit, Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Dig Liver Dis 40:821-6. 2008
    ..Recently, infliximab has been shown to be effective as rescue therapy but little is known about long-term benefits...
  10. ncbi request reprint Infliximab in refractory pouchitis complicated by fistulae following ileo-anal pouch for ulcerative colitis
    A Viscido
    GI Unit, Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Aliment Pharmacol Ther 17:1263-71. 2003
    ..To determine the efficacy of infliximab in the treatment of chronic refractory pouchitis complicated by fistulae following ileal pouch-anal anastomosis for ulcerative colitis...
  11. doi request reprint Clinical trial: ulcerative colitis maintenance treatment with 5-ASA: a 1-year, randomized multicentre study comparing MMX with Asacol
    C Prantera
    Department of Gastroenterology, Azienda Osp S Camillo Forlanini, Rome, Italy
    Aliment Pharmacol Ther 30:908-18. 2009
    ..5-ASA-MMX (1.2 g/tablet) is a 5-aminosalicylic acid formulation, designed for once-daily dosing in the treatment of ulcerative colitis...
  12. doi request reprint Mesalazine vanishing time from rectal mucosa following its topical administration
    M T Pimpo
    S Pietro Fatebenefratelli Hospita, Rome, Italy
    J Crohns Colitis 4:102-5. 2010
    ..M mucosal concentration rapidly decreases 2 days after a 4g enema, but after three days is still higher than OT alone. These results may provide data which would be useful to plan topical therapy and improve adherence to treatment...
  13. ncbi request reprint Use of a 99mTc labeled anti-TNFalpha monoclonal antibody in Crohn's disease: in vitro and in vivo studies
    G Malviya
    Nuclear Medicine Unit, II Faculty of Medicine, La Sapienza University of Rome, Rome, Italy
    Q J Nucl Med Mol Imaging 51:334-42. 2007
    ..The aim of this study was to detect the presence of TNFalpha within the gut mucosa in patients with active CD by using (99m)Tc-labelled chimeric human/mouse monoclonal antibody anti-TNFalpha (Infliximab, Remicade)...
  14. ncbi request reprint Early or late guided missile in the treatment of Crohn's disease?
    R Caprilli
    Gastroenterology Unit, Department of Clinical Sciences, University of Rome La Sapienza, Policlinico Umberto I, Italy
    Dig Liver Dis 37:973-9. 2005
    ..As yet, early use of biological agents remains to be supported by convincing evidence, nevertheless it may be advocated as first-line therapy for newly diagnosed severe Crohn's disease patients, both adults and children...
  15. ncbi request reprint Long-term prevention of post-operative recurrence in Crohn's disease cannot be affected by mesalazine
    C Papi
    Gastroenterology Unit, S Filippo Neri Hospital, Rome, Italy
    J Crohns Colitis 3:109-14. 2009
    ..Mesalazine, the drug more extensively investigated, has been shown to be effective for preventing recurrence in the short-term; however, the overall benefit is small and no data are available on the long-term effectiveness...
  16. ncbi request reprint Efficacy of conventional immunosuppressive drugs in IBD
    R Caprilli
    GI Unit, Department of Clinical Science, University of Rome La Sapienza, Viale del Policlinico 155, 00161 Rome, Italy
    Dig Liver Dis 36:766-80. 2004
    ..Various factors may account for this change of view. Aim of the present review was to summarise key information currently available regarding the use of immunosuppressive drugs in the treatment of inflammatory bowel disease...
  17. ncbi request reprint Two synchronous adenocarcinomas of the small bowel in a patient with undiagnosed Crohn's disease of the terminal ileum
    P Sammartino
    Dipartimento di Chirurgia P Valdoni, University of Rome La Sapienza, Policlinico Umberto I, Via Lancisi, 2 00185, Rome, Italy
    Int J Colorectal Dis 21:388-91. 2006
    ..We report the rare case of a patient in whom surgery for intestinal occlusion disclosed Crohn's disease of the distal ileum complicated by two adenocarcinomas arising within distinct areas of the inflamed bowel...
  18. ncbi request reprint Two mesalazine regimens in the prevention of the post-operative recurrence of Crohn's disease: a pragmatic, double-blind, randomized controlled trial
    R Caprilli
    GI Unit, Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Aliment Pharmacol Ther 17:517-23. 2003
    ..The role of mesalazine in preventing the clinical recurrence of Crohn's disease after surgery has been shown in a meta-analysis of all published studies. No clear relationship, however, has been shown between dosage and response...
  19. ncbi request reprint Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial
    P Vernia
    Dipartmento Scienze Cliniche, Universita di Roma La Sapienza, Rome, Italy
    Eur J Clin Invest 33:244-8. 2003
    ..The present study aimed at confirming, with adequate statistical power, previous data indicating the usefulness of topical butyrate and 5-ASA in the treatment of this condition...
  20. ncbi request reprint CARD 15 and toll-like receptors: the link with Crohn's disease
    R Caprilli
    Gastroenterology Unit, Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Dig Liver Dis 35:753-7. 2003
  21. pmc An unusual treatment for a colonic polyp
    A Viscido
    GI Unit, Department of Clinical Sciences and Gynaecological Unit, University La Sapienza, Rome, Italy
    Gut 53:1000, 1019. 2004
  22. ncbi request reprint Leukocytapheresis as promising therapy for inflammatory bowel disease
    R Caprilli
    Department of Clinical Sciences, GI Unit, Policlinico Umberto I, University of Rome, La Sapienza, Rome, Italy
    Dig Liver Dis 39:435-7. 2007
  23. ncbi request reprint Abdominal tuberculosis with pancreatic involvement: a case report
    F Panzuto
    Digestive and Liver Disease Unit, II School of Medicine, Sant Andrea Hospital, University La Sapienza, Rome, Italy
    Dig Liver Dis 35:283-7. 2003
    ..Tissue culture was positive for Mycobacterium tuberculosis. Once specific medical treatment was started, the pancreatic damage completely resolved...
  24. ncbi request reprint Review article: biological agents in the treatment of Crohn's disease
    R Caprilli
    Gastroenterology Unit, Department of Clinical Sciences, University of Rome La Sapienza, Italy
    Aliment Pharmacol Ther 16:1579-90. 2002
    ..The aim of this review is to provide the clinician with an insight into the randomized controlled trials published in the literature on the use of biological agents in the treatment of Crohn's disease...
  25. ncbi request reprint Effect of predominant methanogenic flora on the outcome of lactose breath test in irritable bowel syndrome patients
    P Vernia
    Cattedra di Gastroenterologia 1, Dipartimento Scienze Cliniche, Universita di Roma La Sapienza, Rome, Italy
    Eur J Clin Nutr 57:1116-9. 2003
    ..The present study was designed to evaluate the effect of predominant fasting methane CH(4) or H(2) production on the outcome of lactose HBT, in a large, homogeneous series of adult patients with irritable bowel syndrome (IBS)...
  26. ncbi request reprint MRI evaluation of Crohn's disease of the small and large bowel with the use of negative superparamagnetic oral contrast agents
    F Maccioni
    Department of Radiology, University of Rome La Sapienza, Policlinico Umberto I, Viale Regina Elena 324, 00161, Rome, Italy
    Abdom Imaging 27:384-93. 2002
  27. ncbi request reprint Long-term oral plus topical mesalazine in frequently relapsing ulcerative colitis
    G Frieri
    Gastroenterology, University of L Aquila, L Aquila, Italy
    Dig Liver Dis 37:92-6. 2005
    ..In cross-sectional studies, it was demonstrated that the therapeutic effect of mesalazine is closely related to its mucosal concentration...
  28. ncbi request reprint Management of refractory fistulizing pouchitis with infliximab
    A Viscido
    Department of Clinical Sciences, University La Sapienza Rome Italy
    Eur Rev Med Pharmacol Sci 8:239-46. 2004
    ..This study provides the long-term follow-up data on the efficacy of infliximab in the treatment of chronic refractory pouchitis complicated by fistulae following ileo-pouch anal anastomosis (IPAA) for ulcerative colitis (UC)...
  29. ncbi request reprint Infliximab and quality of life in steroid-dependent Crohn's disease
    V D'Ovidio
    Dig Liver Dis 36:557-8. 2004
  30. doi request reprint Prevention of colonic fibrosis by Boswellia and Scutellaria extracts in rats with colitis induced by 2,4,5-trinitrobenzene sulphonic acid
    G Latella
    Dipartimento di Medicina Interna e Sanita Pubblica, University of L Aquila, L Aquila, Italy
    Eur J Clin Invest 38:410-20. 2008
    ..The aim of this study was to evaluate the efficacy of a combined therapy of anti-inflammatory Boswellia and antifibrotic Scutellaria extracts on the development of colonic fibrosis in rats...
  31. pmc European evidence based consensus on the diagnosis and management of Crohn's disease: special situations
    R Caprilli
    John Radcliffe Hospital, Oxford OX3 9DU, UK
    Gut 55:i36-58. 2006
    ..The second section on current management addresses treatment of active disease, maintenance of medically induced remission, and surgery of Crohn's disease...
  32. ncbi request reprint The association of MYO9B gene in Italian patients with inflammatory bowel diseases
    A Latiano
    UU OO Gastroenterologia, Endoscopia Digestiva e Lab di Ricerca, Ospedale I R C C S Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
    Aliment Pharmacol Ther 27:241-8. 2008
    ..Variants of myosin IXB (MYO9B) gene, encoding for a motor protein implicated in epithelial permeability, have been recently associated with inflammatory bowel disease...
  33. ncbi request reprint Clinical features in familial cases of Crohn's disease and ulcerative colitis in Italy: a GISC study. Italian Study Group for the Disease of Colon and Rectum
    V Annese
    Divisione di Gastroenterologia, Ospedale CSS-IRCCS, San Giovanni Rotondo, Italy
    Am J Gastroenterol 96:2939-45. 2001
    ..CONCLUSIONS: Our study shows a high rate of concordance for diagnosis and clinical features in UC and, especially, CD families. The disease occurred 15-20 yr earlier than in previous generations without features of increased severity...