F Benazzi

Summary

Affiliation: Hecker Psychiatry Research Center
Country: Italy

Publications

  1. ncbi Gender differences in bipolar-II disorder
    Franco Benazzi
    Eur Arch Psychiatry Clin Neurosci 256:67-71. 2006
  2. ncbi Mood patterns and classification in bipolar disorder
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego USA Collaborating Center, Forli, Italy
    Curr Opin Psychiatry 19:1-8. 2006
  3. ncbi Does temperamental instability support a continuity between bipolar II disorder and major depressive disorder?
    F Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Eur Psychiatry 21:274-9. 2006
  4. ncbi A continuity between bipolar II depression and major depressive disorder?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 30:1043-50. 2006
  5. pmc Various forms of depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Dialogues Clin Neurosci 8:151-61. 2006
  6. ncbi The continuum/spectrum concept of mood disorders: is mixed depression the basic link?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Eur Arch Psychiatry Clin Neurosci 256:512-5. 2006
  7. ncbi Is overactivity the core feature of hypomania in bipolar II disorder?
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego, San Diego, CA, USA
    Psychopathology 40:54-60. 2007
  8. ncbi Challenging DSM-IV criteria for hypomania: diagnosing based on number of no-priority symptoms
    Franco Benazzi
    Hecker Psychiatry Research Center at Forli, Forli, Italy
    Eur Psychiatry 22:99-103. 2007
  9. ncbi Is there a continuity between bipolar and depressive disorders?
    Franco Benazzi
    Hecker Psychiatry Research Center, and Department of Psychiatry, National Health Service, Forli, Italy
    Psychother Psychosom 76:70-6. 2007
  10. ncbi Bipolar disorder--focus on bipolar II disorder and mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Lancet 369:935-45. 2007

Detail Information

Publications110 found, 100 shown here

  1. ncbi Gender differences in bipolar-II disorder
    Franco Benazzi
    Eur Arch Psychiatry Clin Neurosci 256:67-71. 2006
    ..Gender differences in bipolar-II disorder (BP-II) are understudied...
  2. ncbi Mood patterns and classification in bipolar disorder
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego USA Collaborating Center, Forli, Italy
    Curr Opin Psychiatry 19:1-8. 2006
    ..The aim of this review is to highlight recent studies that have questioned the current split of mood disorders into the categories of bipolar and depressive disorders...
  3. ncbi Does temperamental instability support a continuity between bipolar II disorder and major depressive disorder?
    F Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Eur Psychiatry 21:274-9. 2006
    ..According to Kraepelin, temperamental instability was the "foundation" of his unitary view of mood disorders...
  4. ncbi A continuity between bipolar II depression and major depressive disorder?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 30:1043-50. 2006
    ..A bi-modal distribution would support a categorical distinction, and no bi-modality would support continuity...
  5. pmc Various forms of depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Dialogues Clin Neurosci 8:151-61. 2006
    ....
  6. ncbi The continuum/spectrum concept of mood disorders: is mixed depression the basic link?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Eur Arch Psychiatry Clin Neurosci 256:512-5. 2006
    ..No bi-modality, and a dose-response relationship, would not support a categorical distinction...
  7. ncbi Is overactivity the core feature of hypomania in bipolar II disorder?
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego, San Diego, CA, USA
    Psychopathology 40:54-60. 2007
    ..The aim of the study was to find out if overactivity was at least as important as mood change for the diagnosis of hypomania...
  8. ncbi Challenging DSM-IV criteria for hypomania: diagnosing based on number of no-priority symptoms
    Franco Benazzi
    Hecker Psychiatry Research Center at Forli, Forli, Italy
    Eur Psychiatry 22:99-103. 2007
    ..DSM-IV definition of hypomania of bipolar-II disorder (BP-II), which includes elevated/irritable mood change as core feature (i.e., it must always be present), is not based on sound evidence...
  9. ncbi Is there a continuity between bipolar and depressive disorders?
    Franco Benazzi
    Hecker Psychiatry Research Center, and Department of Psychiatry, National Health Service, Forli, Italy
    Psychother Psychosom 76:70-6. 2007
    ..Recent studies questioned the current categorical split of mood disorders into bipolar disorders (BP) and depressive disorders (MDD)...
  10. ncbi Bipolar disorder--focus on bipolar II disorder and mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Lancet 369:935-45. 2007
    ..Controlled studies are needed to investigate treatment of mixed depression; antidepressants can worsen manic and hypomanic symptoms, and mood stabilising agents might be necessary...
  11. ncbi Delineation of the clinical picture of Dysphoric/Mixed Hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego, USA
    Prog Neuropsychopharmacol Biol Psychiatry 31:944-51. 2007
    ..e. combination of syndromal hypomania and depression) compared to Bipolar I Disorder Mixed State (i.e. combination of syndromal mania and depression)...
  12. ncbi Symptoms of depression as possible markers of bipolar II disorder
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 30:471-7. 2006
    ..The study aim was to find which symptoms of depression could be possible cross-sectional markers of BP-II, in order to reduce underdiagnosing BP-II...
  13. ncbi Irritable-hostile depression: further validation as a bipolar depressive mixed state
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 84:197-207. 2005
    ..A veritable tower of Babel indeed. In the present analyses, our aim was to extend previous research on irritable-hostile depression to more specific parameters of bipolarity and depressive mixed state (DMX)...
  14. ncbi The relationship of major depressive disorder to bipolar disorder: continuous or discontinuous?
    Franco Benazzi
    Curr Psychiatry Rep 7:462-70. 2005
    ....
  15. ncbi Borderline personality-bipolar spectrum relationship
    Franco Benazzi
    Hecker Psychiatry Research Center, a University of California at San Diego, USA
    Prog Neuropsychopharmacol Biol Psychiatry 30:68-74. 2006
    ..e., that BPD is a bipolar spectrum disorder or instead that it is unrelated to bipolar disorders. Study aim was to find which items of BPD were related to BP-II, and which instead had no relationship with BP-II...
  16. ncbi Mixed depression: a clinical marker of bipolar-II disorder
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 29:267-74. 2005
    ..Study aim was to test the predictive power for the diagnosis of BP-II of several dimensional definitions of mixed depression, searching for a clinical marker which could reduce the current underdiagnosis of BP-II...
  17. ncbi Agitated depression in bipolar II disorder
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    World J Biol Psychiatry 6:198-205. 2005
    ..To test diagnostic validity or utility of agitated depression (AD) in bipolar II disorder (BP-II)...
  18. ncbi Suicidal ideation and bipolar-II depression symptoms
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Hum Psychopharmacol 20:27-32. 2005
    ..e. it has concurrent hypomanic symptoms). The study aim was to find major depressive episode (MDE) and intra-MDE hypomanic symptoms associated with suicidal ideation...
  19. ncbi Testing atypical depression definitions
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Int J Methods Psychiatr Res 14:82-91. 2005
    ..Pharmacological studies are required to support any new definition of AD, as the current concept of AD is based on different response to TCA antidepressants versus non-AD...
  20. ncbi Toward better probing for hypomania of bipolar-II disorder by using Angst's checklist
    Franco Benazzi
    E Hecker Outpatient Psychiatry Centre, Ravenna, Italy
    Int J Methods Psychiatr Res 13:1-9. 2004
    ..While DSM-IV always requires mood change for the diagnosis of hypomania, the present findings may suggest that overactivity could have the same priority, as suggested by Angst et al. (2003) and by Akiskal et al. (1977, 2001, 2003)...
  21. ncbi Unipolar depression with racing thoughts: a bipolar spectrum disorder?
    Franco Benazzi
    University of California at San Diego, USA, and Hecker Psychiatry Research Center, Ravenna, Italy
    Psychiatry Clin Neurosci 59:570-5. 2005
    ....
  22. ncbi Bipolar family history of the hypomanic symptoms and dimensions of mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Compr Psychiatry 46:399-404. 2005
    ..These data may be important for the genetics of mixed depression. The study aim was to investigate the BPFH of the hypomanic symptoms of mixed depression...
  23. ncbi Impact of temperamental mood lability on depressive mixed state
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Psychopathology 39:19-24. 2006
    ..The study aim was to find the impact of temperamental mood lability (TML) on DMX...
  24. ncbi Psychometric delineation of the most discriminant symptoms of depressive mixed states
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Psychiatry Res 141:81-8. 2006
    ..Beyond its diagnostic significance, the foregoing signs and symptoms are among the clinical features the FDA lists as presaging "suicidality" on antidepressant monotherapy...
  25. ncbi Does age at onset support a dimensional relationship between Bipolar II disorder and major depressive disorder?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    World J Biol Psychiatry 8:105-11. 2007
    ..The bi-modality and dose-response approaches, versus classic diagnostic validators, seem to support a dimensional relationship between BP-II and MDD...
  26. ncbi Impulsivity in bipolar-II disorder: trait, state, or both?
    Franco Benazzi
    University of California at San Diego, CA, USA
    Eur Psychiatry 22:472-8. 2007
    ..In bipolar-II (BP-II) disorder impulsivity (defined as excessive risky activities by DSM-IV-TR) is one of the symptoms of hypomania. It is unclear if impulsivity is also a trait in BP-II...
  27. ncbi Testing new diagnostic criteria for hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Ann Clin Psychiatry 19:99-104. 2007
    ..Angst has suggested new criteria for hypomania, giving priority to overactivity. Study aim was to test the validity of Angst's diagnostic criteria for hypomania...
  28. ncbi A tetrachoric factor analysis validation of mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:186-92. 2008
    ..However, its diagnostic validity and bipolar nature are still not firmly supported. A bipolar nature could have significant treatment impacts...
  29. doi Cyclothymic temperament: the impact of age
    Franco Benazzi
    University of California at San Diego, San Diego, Calif, USA
    Psychopathology 42:165-9. 2009
    ..Testing the impact of age on CT items, as has been done in many mood disorders, could further define its features. The aim of the study was to test the relationship between age and CT items...
  30. ncbi The modified SCID Hypomania Module (SCID-Hba): a detailed systematic phenomenologic probing
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    J Affect Disord 117:131-6. 2009
    ..Our interview follows DSM-IV criteria (apart from the minimum duration, 2 days versus DSM-IV 4 days), i.e. mood change must always been present, but our probing detects more hypomanic episodes than the SCID...
  31. doi What is hypomania? Tetrachoric factor analysis and kernel estimation of DSM-IV hypomanic symptoms
    Franco Benazzi
    J Clin Psychiatry 70:1514-21. 2009
    ..The DSM-IV definition of hypomania, which relies on clinical consensus and historical tradition, includes several "nonspecific" symptoms. The aim of this study was to identify the core symptoms of DSM-IV hypomania...
  32. ncbi A relationship between bipolar II disorder and borderline personality disorder?
    Franco Benazzi
    University of California at San Diego, United States
    Prog Neuropsychopharmacol Biol Psychiatry 32:1022-9. 2008
    ..The relationship between DSM-IV-TR borderline personality disorder (BPD) and bipolar disorders, especially bipolar II disorder (BP-II), is still unclear. Many recent reviews on this topic have come to opposite or different conclusions...
  33. ncbi Defining mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:932-9. 2008
    ..However, it is still unclear if its definition should be based on specific manic symptoms or on a number/score of manic symptoms. Different definitions may have different diagnostic utility, such as treatment impacts...
  34. doi Olanzapine/fluoxetine combination for the treatment of mixed depression in bipolar I disorder: a post hoc analysis
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    J Clin Psychiatry 70:1424-31. 2009
    ....
  35. ncbi How best to identify a bipolar-related subtype among major depressive patients without spontaneous hypomania: superiority of age at onset criterion over recurrence and polarity?
    Franco Benazzi
    Hecker Psychiatry Research Center, Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 107:77-88. 2008
    ..History of high depressive recurrence (without history of mania/hypomania) has been proposed as a mood subtype close to bipolar disorders. Herein we test whether this is the best approach to this question...
  36. doi Classifying mood disorders by age-at-onset instead of polarity
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 33:86-93. 2009
    ..A reshaping of the classification of mood disorders thus seems required. Age-at-onset and recurrence have been suggested to be more clinically and genetically useful in the phenotyping of mood disorders...
  37. ncbi Testing predictors of bipolar-II disorder with a 2-day minimum duration of hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Psychiatry Res 153:153-62. 2007
    ..As PPV is related to disease prevalence, findings need to be replicated in different settings...
  38. ncbi Bipolar II disorder : epidemiology, diagnosis and management
    Franco Benazzi
    Hecker Psychiatry Research Center, a University of California at San Diego USA Collaborating Center at Forli, Italy
    CNS Drugs 21:727-40. 2007
    ..Lamotrigine has shown some efficacy in delaying depression recurrences, but there have also been several negative unpublished studies of the drug in this indication...
  39. ncbi Mixed depression and the dimensional view of mood disorders
    Franco Benazzi
    Hecker Psychiatry Research Center and Department of Psychiatry, National Health Service, Forli, Italy
    Psychopathology 40:431-9. 2007
    ..The study aim was to test a dimensional approach to mood disorders by looking for a progressive grading of age at onset and bipolar family history loading between bipolar II disorder (BP-II) and major depressive disorder (MDD)...
  40. ncbi Reviewing the diagnostic validity and utility of mixed depression (depressive mixed states)
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego, San Diego, CA, USA
    Eur Psychiatry 23:40-8. 2008
    ..To review the diagnostic validity and utility of mixed depression, i.e. co-occurrence of depression and manic/hypomanic symptoms...
  41. ncbi A prediction rule for diagnosing hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli IT, a University of California at San Diego Collaborating Center, San Diego, USA
    Prog Neuropsychopharmacol Biol Psychiatry 33:317-22. 2009
    ..Missing the diagnosis of past hypomania, and thus of bipolar II disorder, is common. Study aim was to find a 'prediction rule' for facilitating the diagnosis of past hypomania...
  42. ncbi Agitated "unipolar" depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy
    Hagop S Akiskal
    Department of Psychiatry and International Mood Center, University of California, La Jolla, CA, USA
    J Affect Disord 85:245-58. 2005
    ..S., Mallya, G., 1987. Criteria for the "soft" bipolar spectrum: treatment implications. Psychopharmacol Bull. 23, 68-73]...
  43. ncbi Gender differences in bipolar II and unipolar depressed outpatients: a 557-case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Ann Clin Psychiatry 11:55-9. 1999
    ..Age at onset was significantly lower in bipolar II females than in unipolar females. This difference was not related to the higher prevalence of atypical features in bipolar II females...
  44. ncbi Bipolar II depression with melancholic features
    F Benazzi
    Department of Psychiatry, National Health Service AUSL, Forli, Italy
    Ann Clin Psychiatry 12:29-33. 2000
    ..The prevalence of melancholic features in bipolar II depression in private practice was higher than previously reported in academic centers...
  45. ncbi Late-life chronic depression: a 399-case study in private practice
    F Benazzi
    Department of Psychiatry, National Health Service, Public Hospital Morgagni, Forli, Italy
    Int J Geriatr Psychiatry 15:1-6. 2000
    ..A major feature of the study was the inclusion of a large number of bipolar II patients, usually not included in previous studies...
  46. ncbi Optimizing the detection of bipolar II disorder in outpatient private practice: toward a systematization of clinical diagnostic wisdom
    Hagop S Akiskal
    International Mood Center, University of California, San Diego, USA
    J Clin Psychiatry 66:914-21. 2005
    ....
  47. ncbi Prevalence and clinical features of atypical depression in depressed outpatients: a 467-case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Psychiatry Res 86:259-65. 1999
    ..Findings suggest that there are important clinical differences between atypical and non-atypical depression in private practice outpatients...
  48. ncbi Late-life atypical major depressive episode: a 358-case study in outpatients
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Am J Geriatr Psychiatry 8:117-22. 2000
    ....
  49. ncbi Major depressive disorder with anger: a bipolar spectrum disorder?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California, San Diego, Calif, USA
    Psychother Psychosom 72:300-6. 2003
    ..The aim of the study was to assess whether major depressive disorder (MDD) with anger could be included in the bipolar spectrum, by comparing it to MDD without anger and to bipolar II disorder...
  50. ncbi A downscaled practical measure of mood lability as a screening tool for bipolar II
    Franco Benazzi
    Outpatient Psychiatry Center Ravenna and Forli, Italy and the Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 84:225-32. 2005
    ..Accordingly, the aim of the present analyses was to test if a practical measure of mood lability was unique to BPII, in comparison with major depressive disorder (MDD)...
  51. ncbi Clinical differences between bipolar II depression and unipolar major depressive disorder: lack of an effect of age
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 75:191-5. 2003
    ..Age difference may be a confounding factor. Study aims were to describe the clinical and family history features of bipolar II versus unipolar depression, and to control for the possible confounding effect of age on clinical features...
  52. ncbi Exploring aspects of DSM-IV interpersonal sensitivity in bipolar II
    F Benazzi
    Department of Psychiatry, National Health Service AUSL, P Solieri 4, 47100 Forli, Italy
    J Affect Disord 60:43-6. 2000
    ..The aim of the study was to find the prevalence of interpersonal rejection sensitivity (IRS) (a personality trait in DSM-IV) in bipolar II and unipolar depression...
  53. ncbi Atypical depression: a variant of bipolar II or a bridge between unipolar and bipolar II?
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, V A Hospital, 3350 La Jolla Village Dr 116 A, La Jolla, San Diego, CA 92161, USA
    J Affect Disord 84:209-17. 2005
    ..Accordingly, we undertook a full scale validation of such a link in a large clinical sample of BP-II and unipolar (UP) major depressive disorder (MDD)...
  54. ncbi Age at onset of bipolar II depressive mixed state
    F Benazzi
    Department of Psychiatry, National Health Service A USL, P Solieri 4, 47100, Forli, Italy
    Psychiatry Res 103:229-35. 2001
    ..DMS2 was more likely in bipolar II with a younger age at onset. Different bipolar II ages at onset did not have an effect on DMS2 clinical correlates...
  55. pmc Is atypical depression a moderate severity depression? A 536-case study
    F Benazzi
    Department of Psychiatry, Morgagni Public Hospital, Forli, Italy
    J Psychiatry Neurosci 24:244-7. 1999
    ..To determine if atypical depression is less common among outpatients with severe depression than among those with nonsevere depression...
  56. ncbi Major depressive episodes with hypomanic symptoms are common among depressed outpatients
    F Benazzi
    Department of Psychiatry, , , Italy
    Compr Psychiatry 42:139-43. 2001
    ..0% of bipolar II subjects. These findings have important treatment implications, as antidepressants may worsen the symptoms of depressive mixed states, and mood stabilizers can be useful...
  57. pmc Early- versus late-onset bipolar II disorder
    F Benazzi
    Department of Psychiatry, Morgagni Public Hospital, Forli, Italy
    J Psychiatry Neurosci 25:53-7. 2000
    ..To compare the clinical features and the outcome between patients with early- and late-onset bipolar II disorder...
  58. ncbi The DSM-IV and ICD-10 categories of recurrent [major] depressive and bipolar II disorders: evidence that they lie on a dimensional spectrum
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, VA Psychiatry Service, 116A, 3350 La Jolla Village Drive, 92161, USA
    J Affect Disord 92:45-54. 2006
    ..We used the ongoing Ravenna-San Diego Collaboration database to examine this question with respect to major depressive disorder (MDD) and bipolar II (BP-II)...
  59. ncbi Agitated depression: unipolar? Bipolar? Or both?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California, San Diego, USA
    Ann Clin Psychiatry 14:97-104. 2002
    ..Further studies on this topic are needed...
  60. doi Is a family history of bipolar disorder a risk factor for migraine among affectively ill patients?
    Steven C Dilsaver
    Comprehensive Doctors Medical Group, Arcadia, Calif, USA
    Psychopathology 42:119-23. 2009
    ..The aim was to determine whether having a family history of bipolar disorder (BPD) or unipolar major depressive disorder (MDD) is associated with an increased likelihood of having migraine headaches...
  61. ncbi Does the FDA proposed list of possible correlates of suicidality associated with antidepressants apply to an adult private practice population?
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, CA, USA
    J Affect Disord 94:105-10. 2006
    ..In this report we examine the relevance of the "FDA list" for adults...
  62. ncbi Bipolar II depression in late life: prevalence and clinical features in 525 depressed outpatients
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, 47100 Forli, Italy
    J Affect Disord 66:13-8. 2001
    ....
  63. ncbi Characteristics of bipolar II patients with interpersonal rejection sensitivity
    F Benazzi
    Department of Psychiatry, National Health Service A USL, Forli, Italy
    Psychiatry Clin Neurosci 54:499-501. 2000
    ....
  64. ncbi Delineating bipolar II mixed states in the Ravenna-San Diego collaborative study: the relative prevalence and diagnostic significance of hypomanic features during major depressive episodes
    F Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 67:115-22. 2001
    ....
  65. ncbi Chronic depression subtypes: a 257 case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Depress Anxiety 10:81-4. 1999
    ..Chronic depression subtypes had significantly longer duration of illness, less comorbidity, and more recurrences than nonchronic depression. These findings do not support the DSM-IV subtyping of chronic depression...
  66. ncbi Psychotic late-life depression: a 376-case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Int Psychogeriatr 11:325-32. 1999
    ..Findings were related to psychosis or to age, and not to specific features of psychotic late-life depression. These results support a unitary view of psychotic depression...
  67. ncbi Bipolar versus unipolar psychotic outpatient depression
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    J Affect Disord 55:63-6. 1999
    ..The relationship between bipolar and unipolar psychotic depression has not been well studied. Therefore, the aim of the present study was to compare bipolar with unipolar psychotic outpatient depression...
  68. ncbi The Montgomery Asberg Depression Rating Scale in bipolar II and unipolar out-patients: a 405-patient case study
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    Psychiatry Clin Neurosci 53:429-31. 1999
    ..Comparisons among atypical and non-atypical bipolar II and unipolar patients showed that only MADRS items of 'reduced sleep' and 'reduced appetite' were significantly different between atypical and non-atypical patients...
  69. ncbi Factor analysis of the Montgomery Asberg Depression Rating Scale in 251 bipolar II and 306 unipolar depressed outpatients
    F Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 25:1369-76. 2001
    ..Different factor structure (between bipolar II and unipolar depression) supports previous findings that response to antidepressants and biology may be different in bipolar II and unipolar depression...
  70. ncbi Which could be a clinically useful definition of depressive mixed state?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California in San Diego USA Collaborating Center, San Diego, CA, USA
    Prog Neuropsychopharmacol Biol Psychiatry 26:1105-11. 2002
    ..Study aim was to find if the best clinically useful definition of DMX was one based on a minimum number of hypomanic symptoms, or instead one based on the combination of specific hypomanic symptoms...
  71. ncbi Depressive mixed state: dimensional versus categorical definitions
    Franco Benazzi
    Outpatient Psychiatry Center, Via Pozzetto 17, 48015 Castiglione di Cervia RA, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 27:129-34. 2003
    ..It is still unclear how to best define DMX. The study's aim was to test a categorical versus a dimensional definition of DMX...
  72. ncbi Is there a link between atypical and early-onset "unipolar" depression and bipolar II disorder?
    Franco Benazzi
    Outpatient Psychiatry Center, a University of California San Diego Collaborating Center, Ravenna and Forli, and Department of Psychiatry, National Health Service of Forlì, Italy
    Compr Psychiatry 44:102-9. 2003
    ..These results support a link of atypical and early-onset "unipolar" depression with bipolar II disorder, and support Pages and Dunner's suggestion to combine bipolar II and recurrent unipolar into a single group...
  73. ncbi Challenging the unipolar-bipolar division: does mixed depression bridge the gap?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 31:97-103. 2007
    ..A correlation between intradepressive hypomanic symptoms and depressive symptoms could support such a continuum, but other explanations of a correlation are possible...
  74. ncbi Agitated depression: a valid depression subtype?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 28:1279-85. 2004
    ..It is not classified in DSM-IV and ICD-10 classification of mental and behavioural disorder (ICD-10). Some data support its subtyping. This study aims to test the subtyping of AD...
  75. ncbi Toward a clinical delineation of dysphoric hypomania - operational and conceptual dilemmas
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, La Jolla, 92161, USA
    Bipolar Disord 7:456-64. 2005
    ..Analogous to the DSM-IV approach in the diagnosis of manic mixed state, in this exploratory study we operationalized DH as coexisting full syndromal hypomanic and major depressive states...
  76. ncbi Prevalence of bipolar II disorder in outpatient depression: a 203-case study in private practice
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    J Affect Disord 43:163-6. 1997
    ....
  77. ncbi Prevalence and clinical correlates of residual depressive symptoms in bipolar II disorder
    F Benazzi
    Department of Psychiatry, National Health Service AUSL, Forli, Italy
    Psychother Psychosom 70:232-8. 2001
    ..The study aims were to assess the prevalence and clinical correlates of persistent residual depressive symptoms in bipolar II disorder...
  78. ncbi The clinical picture of bipolar II outpatient depression in private practice
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, National Health Service, Forli, Italy
    Psychopathology 34:81-4. 2001
    ..The presence of DSM-IV atypical features predicted bipolar II diagnosis with 63% probability...
  79. ncbi Female vs. male outpatient depression: a 448-case study in private practice
    F Benazzi
    Department of Psychiatry, National Health Service AUSL, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 24:475-81. 2000
    ..3. Private practice outpatient female depression (chronic, psychotic, or recurrent) was not more severe than male depression...
  80. ncbi Highly recurrent unipolar may be related to bipolar II
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Compr Psychiatry 43:263-8. 2002
    ..Pages and Dunner (1997) view that recurrent unipolar and bipolar II could be part of a single mood disorder, and Goodwin and Jamison (1990) view that recurrence is the key feature of mood disorders are partly supported by the findings...
  81. ncbi Psychopathologic correlates of suicidal ideation in major depressive outpatients: is it all due to unrecognized (bipolar) depressive mixed states?
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, Calif 92161, USA
    Psychopathology 38:273-80. 2005
    ..Recent transatlantic concern about suicidality in patients receiving antidepressants prompted us to examine the psychopathologic correlates of suicidal ideation occurring in clinically depressed patients...
  82. ncbi Refining the evaluation of bipolar II: beyond the strict SCID-CV guidelines for hypomania
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 73:33-8. 2003
    ..Our objective was to further refine the strict SCID-CV guidelines for hypomania in depressed outpatients...
  83. ncbi Inter-episode mood lability in mood disorders: residual symptom or natural course of illness?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna and the Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Clin Neurosci 58:480-6. 2004
    ....
  84. ncbi Family history validation of the bipolar nature of depressive mixed states
    Hagop S Akiskal
    VA Medical Center, University of California at San Diego, VA Psychiatry Service 116 A, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
    J Affect Disord 73:113-22. 2003
    ..Our aims were to find the sensitivity and specificity of DMX for the diagnosis of bipolar II disorder, and validate it against familial bipolarity...
  85. ncbi Family history validation of a definition of mixed depression
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Compr Psychiatry 46:159-66. 2005
    ..The study aim was to test different definitions of mixed depression, defined as a depression with concurrent hypomanic symptoms...
  86. ncbi Bipolar II depressive mixed state: finding a useful definition
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Compr Psychiatry 44:21-7. 2003
    ..A cross-sectional marker like DMX3 may increase the probability of making the correct diagnosis of bipolar II, and therefore may be a useful definition of DMX...
  87. ncbi Depression with racing thoughts
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Res 120:273-82. 2003
    ..Depression with racing thoughts was very common in depressed outpatients, and was associated with suicidal ideation. Possible differential effects of antidepressants vs. mood stabilizers and antipsychotics are discussed...
  88. ncbi Is depressive mixed state a transition between depression and hypomania?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Eur Arch Psychiatry Clin Neurosci 254:69-75. 2004
    ..Study aim was to find if DMX in bipolar II disorder was often a transition period between depression and hypomania, as suggested by Kraepelin...
  89. ncbi Atypical bipolar II depression compared with atypical unipolar depression and nonatypical bipolar II depression
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni Forlì, Italy
    Psychopathology 33:100-2. 2000
    ..As different ages at onset may identify distinct subtypes of depression, this finding might suggest that atypical bipolar II depression may be distinct from both atypical unipolar depression and nonatypical bipolar II depression...
  90. ncbi Depressive mixed state: testing different definitions
    F Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Clin Neurosci 55:647-52. 2001
    ..Findings have important clinical and treatment implications because antidepressants may worsen DMX, and the presence of DMX may induce clinicians to assess systematically and carefully the history of past hypomania...
  91. ncbi Antidepressant-associated hypomania in outpatient depression: a 203-case study in private practice
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, Forli, Italy
    J Affect Disord 46:73-7. 1997
    ..Both unipolar and bipolar switchers had instead early age at onset and frequent atypical features, suggesting that these factors might increase the risk of switching in unipolar depression...
  92. ncbi Early-onset versus late-onset bipolar II chronic depression
    F Benazzi
    Department of Psychiatry, National Health Service A USL, Foril, Italy
    Depress Anxiety 13:45-9. 2001
    ..Results support the subtyping of bipolar II chronic depression in EO and LO on the basis of different clinical features...
  93. ncbi Sensitivity and specificity of clinical markers for the diagnosis of bipolar II disorder
    F Benazzi
    Department of Psychiatry, National Health Service, , Italy
    Compr Psychiatry 42:461-5. 2001
    ..The low reliability of bipolar II diagnosis based on history of hypomania may be improved by two cross-sectional clinical markers...
  94. ncbi Early-onset versus late-onset atypical depression: unipolar and bipolar II
    F Benazzi
    Department of Psychiatry, Public Hospital Morgagni, National Health Service, 47100, Forli, Italy
    J Affect Disord 61:95-9. 2000
    ..To find differences between early- and late-onset atypical depression (AD)...
  95. ncbi Course and outcome of bipolar II disorder: a retrospective study
    F Benazzi
    Department of Psychiatry, National Health Service, AUSL, Forli, Italy
    Psychiatry Clin Neurosci 55:67-70. 2001
    ..Results support subtyping of Bipolar II in a small good-outcome group, and a large moderate-poor-outcome group...
  96. ncbi Atypical depression with hypomanic symptoms
    F Benazzi
    Department of Psychiatry, National Health Service A USL, P Solieri 4, 47100 Forli, Italy
    J Affect Disord 65:179-83. 2001
    ..The aims of this study were to find the prevalence and clinical features of DMS in atypical depression...
  97. ncbi Female depression before and after menopause
    F Benazzi
    Department of Psychiatry, National Health Service A USL, Forli, Italy
    Psychother Psychosom 69:280-3. 2000
    ..Aim of the study was to compare female depression with onset before menopause with female depression with onset after menopause, to find out if endocrinological changes had an impact on depression...
  98. ncbi Possible bipolar nature of irritability in major depressive disorder
    Franco Benazzi
    J Clin Psychiatry 66:1072; author reply 1073. 2005
  99. ncbi Atypical depressive syndromes in varying definitions
    Jules Angst
    Zurich University Psychiatric Hospital, Lenggstrasse 31, PO Box 1931, 8032 Zurich, Switzerland
    Eur Arch Psychiatry Clin Neurosci 256:44-54. 2006
    ..Using prospective data from a community sample, this paper identifies criteria (and correlates) for an AD syndrome that maximizes the association with female sex and bipolar-II...
  100. ncbi Differential patterns of lifetime multiple anxiety disorder comorbidity between Latino adults with bipolar I and major depressive disorders
    Steven C Dilsaver
    Comprehensive Doctors Medical Group Inc, Arcadia, California and the Rio Grande City Community Mental Health Mental Retardation Clinic, Rio Grande City, Texas, USA
    Bull Menninger Clin 72:130-48. 2008
    ....
  101. ncbi Should mood reactivity be included in the DSM-IV atypical features specifier?
    Franco Benazzi
    Eur Arch Psychiatry Clin Neurosci 252:135-40. 2002
    ..The study aim was to test whether mood reactivity should be included in DSM-IV atypical features specifier...