Giulia Guarguaglini

Summary

Country: Italy

Publications

  1. ncbi The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles
    Giulia Guarguaglini
    Department of Cell Biology, Max Planck Institute for Biochemistry, D 82152, Martinsried, Germany
    Mol Biol Cell 16:1095-107. 2005
  2. ncbi Importin beta is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells
    Marilena Ciciarello
    Institute of Molecular Biology and Pathology, Section of Genetics, CNR Consiglio Nazionale delle Ricerche, Via degli Apuli 4, Rome 00185, Italy
    J Cell Sci 117:6511-22. 2004
  3. ncbi Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects
    Kiku e K Tachibana
    Medical Research Council Cancer Cell Unit, Hutchison MRC Research Centre, Hills Road, Cambridge CB2 2XZ, UK
    EMBO Rep 6:1052-7. 2005
  4. ncbi A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association
    Maria De Luca
    Institute of Molecular Biology and Pathology, CNR, University of Rome La Sapienza, Rome, Italy
    Cell Cycle 5:296-303. 2006
  5. ncbi Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells
    Liliana Torosantucci
    IBPM Institute of Molecular Biology and Pathology, National Research Council, c o University of Rome La Sapienza, 00185 Rome, Italy
    Mol Biol Cell 19:1873-82. 2008

Collaborators

  • E A Nigg
  • Stefan Duensing
  • Maria De Luca
  • Patrizia Lavia
  • Liliana Torosantucci
  • Kiku e K Tachibana
  • Marilena Ciciarello
  • Francesca Degrassi
  • Michael A Gonzalez
  • Ronald A Laskey
  • Kiku-E K Tachibana
  • Catherine Thibier
  • Rosamaria Mangiacasale
  • Enzo Marchetti
  • Barbara Di Fiore

Detail Information

Publications5

  1. ncbi The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles
    Giulia Guarguaglini
    Department of Cell Biology, Max Planck Institute for Biochemistry, D 82152, Martinsried, Germany
    Mol Biol Cell 16:1095-107. 2005
    ..We show that Cep170 labeling can be used to discriminate bona fide centriole overduplication from centriole amplification that results from aborted cell division...
  2. ncbi Importin beta is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells
    Marilena Ciciarello
    Institute of Molecular Biology and Pathology, Section of Genetics, CNR Consiglio Nazionale delle Ricerche, Via degli Apuli 4, Rome 00185, Italy
    J Cell Sci 117:6511-22. 2004
    ..Targeting of TPX2/importin-beta complexes to poles is a key aspect in Ran-dependent control of the mitotic apparatus in mammalian cells...
  3. ncbi Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects
    Kiku e K Tachibana
    Medical Research Council Cancer Cell Unit, Hutchison MRC Research Centre, Hills Road, Cambridge CB2 2XZ, UK
    EMBO Rep 6:1052-7. 2005
    ..These results show that the consequences of geminin loss exceed its immediate role in DNA replication and extend to promoting chromosome mis-segregation in mitosis...
  4. ncbi A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association
    Maria De Luca
    Institute of Molecular Biology and Pathology, CNR, University of Rome La Sapienza, Rome, Italy
    Cell Cycle 5:296-303. 2006
    ..Based on these results therefore a hierarchical functional relation between Plk1 and the Aurora-A/TPX2 pathway emerges...
  5. ncbi Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells
    Liliana Torosantucci
    IBPM Institute of Molecular Biology and Pathology, National Research Council, c o University of Rome La Sapienza, 00185 Rome, Italy
    Mol Biol Cell 19:1873-82. 2008
    ..The complex of RanGTP, the export receptor Crm1, and nuclear export signal-bearing proteins regulates microtubule nucleation at kinetochores...