Gian Luigi Gigli

Summary

Country: Italy

Publications

  1. ncbi request reprint Epidemiology and clinical features of sleep disorders in extrapyramidal disease
    Stefania Brotini
    Department of Neurosciences, Neurology Neurophysiopathology Unit, Sleep Disorders Center, S Maria della Misericordia General Hospital, Piazzale S Maria della Misericordia, 15, 33100 Udine, Italy
    Sleep Med 5:169-79. 2004
  2. ncbi request reprint Restless legs syndrome in end-stage renal disease
    Gian Luigi Gigli
    Neurologia Neurofisiopatologia, Department of Neurosciences, Center for Sleep Medicine, Azienda Ospedaliera S Maria della Misericordia, Piazzale S Maria della Misericordia, 15 33100 Udine, Italy
    Sleep Med 5:309-15. 2004
  3. ncbi request reprint The withdrawal of nutrition and hydration in the vegetative state patient: societal dimension and issues at stake for the medical profession
    Gian Luigi Gigli
    Department of Neurosciences, Ospedale Santa Maria della Misericordia, Udine, Italy
    NeuroRehabilitation 19:315-28. 2004
  4. ncbi request reprint Stroke incidence and 30-day and six-month case fatality rates in Udine, Italy: a population-based prospective study
    Francesco Janes
    Department of Experimental and Clinical Medical Sciences, University of Udine Medical School, Udine, Italy Department of Neurosciences, S Maria della Misericordia University Hospital, Udine, Italy
    Int J Stroke 8:100-5. 2013
  5. doi request reprint Restless legs syndrome in dialysis patients: a comparison between hemodialysis and continuous ambulatory peritoneal dialysis
    Giovanni Merlino
    Department of Neurosciences, Santa Maria della Misericordia University Hospital, Udine, Italy
    Neurol Sci 33:1311-8. 2012
  6. doi request reprint ADMET considerations for restless leg syndrome drug treatments
    Stefano de Biase
    Department of Neurosciences, Santa Maria della Misericordia University Hospital, Udine, Italy
    Expert Opin Drug Metab Toxicol 8:1247-61. 2012
  7. doi request reprint Incidence of transient ischemic attack and early stroke risk: validation of the ABCD2 score in an Italian population-based study
    Iacopo Cancelli
    Department of Neurosciences, S Maria della Misericordia University Hospital, and Department of Experimental and Clinical Medicine, University of Udine Medical School, Piazza Santa Maria della Misericordia, 33100 Udine, Italy
    Stroke 42:2751-7. 2011
  8. doi request reprint Drugs with anticholinergic properties as a risk factor for cognitive impairment in elderly people: a population-based study
    Iacopo Cancelli
    Department of Neurology, S Maria della Misericordia University Hospital, University of Udine Medical School, Udine, Italy
    J Clin Psychopharmacol 28:654-9. 2008
  9. doi request reprint Gabapentin enacarbil in restless legs syndrome
    Giovanni Merlino
    Sleep Disorders Center, Dept of Neurosciences, Santa Maria della Misericordia University Hospital, Udine, Italy
    Drugs Today (Barc) 46:3-11. 2010
  10. ncbi request reprint A case-control study on restless legs syndrome in nondialyzed patients with chronic renal failure
    Giovanni Merlino
    Department of Neurosciences, Sleep Disorders Center, Santa Maria della Misericordia University Hospital, Udine, Italy
    Mov Disord 25:1019-25. 2010

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Epidemiology and clinical features of sleep disorders in extrapyramidal disease
    Stefania Brotini
    Department of Neurosciences, Neurology Neurophysiopathology Unit, Sleep Disorders Center, S Maria della Misericordia General Hospital, Piazzale S Maria della Misericordia, 15, 33100 Udine, Italy
    Sleep Med 5:169-79. 2004
    ..There are no data available at present as to the role of gender in sleep disturbances. Finally, the benefit of sleep on extrapyramidal diseases will be addressed, taking into account that the above causes may modify the effects of sleep...
  2. ncbi request reprint Restless legs syndrome in end-stage renal disease
    Gian Luigi Gigli
    Neurologia Neurofisiopatologia, Department of Neurosciences, Center for Sleep Medicine, Azienda Ospedaliera S Maria della Misericordia, Piazzale S Maria della Misericordia, 15 33100 Udine, Italy
    Sleep Med 5:309-15. 2004
    ..Moreover, some data were collected prior to the recent improvements in dialysis techniques, pharmacological therapies and to the establishment of internationally recognised diagnostic criteria for RLS...
  3. ncbi request reprint The withdrawal of nutrition and hydration in the vegetative state patient: societal dimension and issues at stake for the medical profession
    Gian Luigi Gigli
    Department of Neurosciences, Ospedale Santa Maria della Misericordia, Udine, Italy
    NeuroRehabilitation 19:315-28. 2004
    ..In the second part, the authors outline the changes that this attitude can provoke in the integrity and the juridical status of the medical and nursing professions, and its potential impact on the society at large...
  4. ncbi request reprint Stroke incidence and 30-day and six-month case fatality rates in Udine, Italy: a population-based prospective study
    Francesco Janes
    Department of Experimental and Clinical Medical Sciences, University of Udine Medical School, Udine, Italy Department of Neurosciences, S Maria della Misericordia University Hospital, Udine, Italy
    Int J Stroke 8:100-5. 2013
    ..Stroke incidence in high-income countries is reported to decrease, and new data on stroke incidence and outcome are needed to design stroke services and to ameliorate stroke management...
  5. doi request reprint Restless legs syndrome in dialysis patients: a comparison between hemodialysis and continuous ambulatory peritoneal dialysis
    Giovanni Merlino
    Department of Neurosciences, Santa Maria della Misericordia University Hospital, Udine, Italy
    Neurol Sci 33:1311-8. 2012
    ..Dialysis schedule was associated with RLS in HD patients, while female sex was related to RLS in CAPD patients. Awareness concerning RLS identification and treatment in HD and CAPD patients is recommended...
  6. doi request reprint ADMET considerations for restless leg syndrome drug treatments
    Stefano de Biase
    Department of Neurosciences, Santa Maria della Misericordia University Hospital, Udine, Italy
    Expert Opin Drug Metab Toxicol 8:1247-61. 2012
    ..In patients affected by severe RLS, a pharmacological treatment is mandatory...
  7. doi request reprint Incidence of transient ischemic attack and early stroke risk: validation of the ABCD2 score in an Italian population-based study
    Iacopo Cancelli
    Department of Neurosciences, S Maria della Misericordia University Hospital, and Department of Experimental and Clinical Medicine, University of Udine Medical School, Piazza Santa Maria della Misericordia, 33100 Udine, Italy
    Stroke 42:2751-7. 2011
    ..However, population-based studies are still needed. We aimed to provide data on TIA incidence and to evaluate the ABCD2 predictive ability for early recurrent stroke in a population-based study...
  8. doi request reprint Drugs with anticholinergic properties as a risk factor for cognitive impairment in elderly people: a population-based study
    Iacopo Cancelli
    Department of Neurology, S Maria della Misericordia University Hospital, University of Udine Medical School, Udine, Italy
    J Clin Psychopharmacol 28:654-9. 2008
    ..30; 95% confidence interval, 1.19-4.45). Our data suggest that ACH drug intake should be regarded a potentially modifiable risk factor for cognitive impairment in the elderly...
  9. doi request reprint Gabapentin enacarbil in restless legs syndrome
    Giovanni Merlino
    Sleep Disorders Center, Dept of Neurosciences, Santa Maria della Misericordia University Hospital, Udine, Italy
    Drugs Today (Barc) 46:3-11. 2010
    ..Further studies are required to confirm the long term efficacy and safety of gabapentin enacarbil on the symptoms of RLS...
  10. ncbi request reprint A case-control study on restless legs syndrome in nondialyzed patients with chronic renal failure
    Giovanni Merlino
    Department of Neurosciences, Sleep Disorders Center, Santa Maria della Misericordia University Hospital, Udine, Italy
    Mov Disord 25:1019-25. 2010
    ..Nephrologists should investigate and treat RLS in their nondialyzed patients with CRF. In particular, physicians should carefully investigate women and patients with iron deficiency in the presence of RLS symptoms...
  11. doi request reprint Clinical experience with pramipexole in the treatment of restless legs syndrome
    Giovanni Merlino
    Santa Maria della Misericordia University Hospital, Sleep Disorder Center, Neurology and Clinical Neurophysiology, Udine, Italy
    Expert Opin Drug Metab Toxicol 4:225-35. 2008
    ..Augmentation, the most common side effect of levodopa, is less prevalent after treatment with pramipexole. In addition, the recurrence of unpleasant symptoms due to pramipexole is uncommon...
  12. ncbi request reprint Gabapentin enacarbil, a gabapentin prodrug for the treatment of the neurological symptoms associated with disorders such as restless legs syndrome
    Giovanni Merlino
    Sleep Disorder Center, Santa Maria della Misericordia University Hospital, Piazzale S Maria della Misericordia, Udine, Italy
    Curr Opin Investig Drugs 10:91-102. 2009
    ..The author concludes that additional studies are required in order to better assess the efficacy and safety of gabapentin enacarbil on RLS...
  13. doi request reprint Association of body rolling, leg rolling, and rhythmic feet movements in a young adult: A video-polysomnographic study performed before and after one night of clonazepam
    Giovanni Merlino
    Sleep Disorder Center, Neurology and Clinical Neurophysiology, Santa Maria della Misericordia University Hospital, Udine, Italy
    Mov Disord 23:602-7. 2008
    ..We discuss the characteristics of the RMD and the response to the first administration of pharmacological treatment, observed in our patient...
  14. pmc Association of restless legs syndrome in type 2 diabetes: a case-control study
    Giovanni Merlino
    Sleep Disorder Center Neurology and Clinical Neurophysiology, Santa Maria della Misericordia University Hospital, Udine, Italy
    Sleep 30:866-71. 2007
    ....
  15. ncbi request reprint Investigational approaches to therapies for restless legs syndrome
    Stefano de Biase
    University of Udine Medical School, Department of Experimental and Clinical Medical Sciences, Neurology Unit, Udine, Italy
    Expert Opin Investig Drugs 23:847-56. 2014
    ..In patients affected by severe RLS, pharmacological treatment is mandatory...
  16. ncbi request reprint Sleep disturbances in dialysis patients
    Giovanni Merlino
    Sleep Disorder Center, Neurology and Clinical Neurophysiology, Santa Maria della Misericordia University Hospital, Piazza Santa Maria della Misericordia, Udine, Italy
    J Nephrol 21:S66-70. 2008
    ..However, literature and personal data suggest that undertreatment is common, calling to higher awareness of sleep disturbances among nephrologists...
  17. doi request reprint Changes of cortical excitability after dopaminergic treatment in restless legs syndrome
    Anna Scalise
    Department of Neurosciences, S Maria della Misericordia University Hospital, Udine, Italy
    Sleep Med 11:75-81. 2010
    ..The purpose of our study was to compare practice-dependent plasticity in RLS patients before and after a month of dopaminergic treatment...
  18. doi request reprint Drugs with anticholinergic properties: cognitive and neuropsychiatric side-effects in elderly patients
    Iacopo Cancelli
    Department of Neurology, Santa Maria della Misericordia University Hospital, Udine, Italy
    Neurol Sci 30:87-92. 2009
    ..The threat of developing cognitive impairment, psychosis and delirium will be particularly analyzed...
  19. ncbi request reprint Lacosamide for the treatment of epilepsy
    Stefano de Biase
    University of Udine Medical School, Department of Experimental and Clinical Medical Sciences, Neurology Unit, Piazza Santa Maria della Misercordia, 15 33100 Udine, Italy
    Expert Opin Drug Metab Toxicol 10:459-68. 2014
    ..In addition, the results of ongoing trials will help to confirm if LCM could be used as a monotherapy regimen in the treatment of partial-onset seizures and generalized tonic-clonic seizures. ..
  20. ncbi request reprint The acute effect of a low dosage of pramipexole on severe idiopathic restless legs syndrome: an open-label trial
    Giovanni Merlino
    Sleep Disorder Centre, Department of Neurology, Santa Maria della Misericordia University Hospital, Udine, Italy
    Neuropsychobiology 54:195-200. 2006
    ..No data regarding the acute effect of low doses of pramipexole have been reported...
  21. doi request reprint Neurophysiology of juvenile myoclonic epilepsy
    Anna Serafini
    Center of Sleep Medicine, Neurology Unit, University Hospital S Maria della Misericordia, Udine, Italy
    Epilepsy Behav 28:S30-9. 2013
    ..In this review, we present the EEG characteristics of JME with particular emphasis on the pathophysiology of MJ and on the role of sleep deprivation on interictal and ictal changes...
  22. doi request reprint Should the definition of "sleep hygiene" be antedated of a century? A historical note based on an old book by Paolo Mantegazza, rediscovered. To place in a new historical context the development of the concept of sleep hygiene
    Gian Luigi Gigli
    Center of Sleep Medicine, Department of Neurosciences, Santa Maria della Misericordia University Hospital, Udine, Italy
    Neurol Sci 34:755-60. 2013
    ..Hauri keeps the merit of giving more solid scientific roots to the concept of sleep hygiene and of inserting it in the frame of modern sleep medicine...
  23. doi request reprint Sleep-related movement disorders
    Giovanni Merlino
    Department of Neurosciences, Santa Maria della Misericordia University Hospital, Udine, Italy
    Neurol Sci 33:491-513. 2012
    ..Patients reporting poor sleep due to these abnormal movements should undergo non-pharmacological or pharmacological treatments...
  24. doi request reprint Drugs with anticholinergic properties: a potential risk factor for psychosis onset in Alzheimer's disease?
    Iacopo Cancelli
    Santa Maria della Misericordia University Hospital, Department of Neurology, Udine, Italy
    Expert Opin Drug Saf 8:549-57. 2009
    ..This review focuses on biological and clinical data which suggest that anti-cholinergic drugs should be regarded as a potential risk factor for psychosis in Alzheimer's disease...
  25. doi request reprint Sleep before and after temporal lobe epilepsy surgery
    Anna Serafini
    Epilepsy Unit, Hopital Gui de Chauliac, Montpellier, France
    Seizure 21:260-5. 2012
    ....
  26. ncbi request reprint Nerve fibre layer analysis with GDx with a variable corneal compensator in patients with multiple sclerosis
    Giovanni Della Mea
    Department of Ophthalmology, S Maria della Misericordia Hospital, Udine, Italy
    Ophthalmologica 221:186-9. 2007
    ..To evaluate the ability of GDx with variable corneal compensator (VCC) compared to visual-evoked potentials (VEPs) and standard automated perimetry (SAP) in the detection of early optic nerve damage in patients with multiple sclerosis (MS)...
  27. ncbi request reprint The accuracy of discharge diagnosis coding for Amyotrophic Lateral Sclerosis in a large teaching hospital
    Federica Edith Pisa
    Institute of Hygiene and Epidemiology, DPMSC, Azienda Ospedaliero Universitaria di Udine, Via Colugna 40, 33100, Udine, Italy
    Eur J Epidemiol 24:635-40. 2009
    ....
  28. ncbi request reprint Increasing cortical excitability: a possible explanation for the proconvulsant role of sleep deprivation
    Anna Scalise
    Department of Neurosciences, S Maria della Misericordia Hospital, Udine, Italy
    Sleep 29:1595-8. 2006
    ..In order to evaluate the effects of SD on cortical excitability, we studied the effects of sleep loss on healthy subjects by transcranial magnetic stimulation (TMS)...
  29. ncbi request reprint Absence of postexercise and delayed facilitation of motor cortex excitability in restless legs syndrome: evidence of altered cortical plasticity?
    Anna Scalise
    Department of Neurosciences, S Maria della Misericordia Hospital, Udine, Italy
    Sleep 29:770-5. 2006
    ..Previous studies have suggested alterations in motor cortex function in RLS. We aimed to compare motor cortex plasticity in subjects with RLS versus healthy controls...
  30. ncbi request reprint Motor cortex excitability in restless legs syndrome
    Anna Scalise
    Department of Neurosciences, S Maria della Misericordia Hospital, Piazzale S Maria della Misericordia 15, Udine, Italy
    Sleep Med 5:393-6. 2004
    ..In this study we used TMS to define motor cortical excitability in RLS subjects...
  31. ncbi request reprint Sleep disorders in patients with end-stage renal disease undergoing dialysis therapy
    Giovanni Merlino
    Sleep Disorder Center, Neurology Unit, S Maria della Misericordia Hospital and Udine University Hospital, 33100 Udine, Italy
    Nephrol Dial Transplant 21:184-90. 2006
    ..The aim of this study was to investigate the prevalence of sleep disorders in a large population of uraemic patients recruited from 20 different dialytic centres in Triveneto...
  32. pmc Multicenter case-control study on restless legs syndrome in multiple sclerosis: the REMS study
    Mauro Manconi
    Sleep Disorders Center, Scientific Institute and Ospedale San Raffaele, Via Stamira d Ancona 20, 20127 Milan, Italy
    Sleep 31:944-52. 2008
    ..To verify the existence of a symptomatic form of restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and to identify possible associated risk factors...
  33. ncbi request reprint Foreword
    Gian Luigi Gigli
    NeuroRehabilitation 19:271-2. 2004
  34. ncbi request reprint Specific impairments of rule induction in different frontal lobe subgroups
    Carlo Reverberi
    International School for Advanced Studies, Trieste, Italy
    Neuropsychologia 43:460-72. 2005
    ....
  35. ncbi request reprint Considerations on the scientific and ethical problems related to vegetative state
    Gian Luigi Gigli
    Med Etika Bioet 11:20-1. 2004
  36. ncbi request reprint Statement on euthanasia in children
    Gian Luigi Gigli
    Med Etika Bioet 11:22. 2004