Lisa Gianesello

Summary

Affiliation: Istituto Oncologico Veneto
Location: Padova, Italy

Publications

  1. ncbi Insulin-like factor 3 gene mutations in testicular dysgenesis syndrome: clinical and functional characterization
    A Ferlin
    Department of Histology, Microbiology and Medical Biotechnologies, Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Mol Hum Reprod 12:401-6. 2006
  2. pmc Profiling insulin like factor 3 (INSL3) signaling in human osteoblasts
    Alberto Ferlin
    Section of Clinical Pathology, Department of Histology, Microbiology and Medical Biotechnologies, University of Padova, Padova, Italy
    PLoS ONE 6:e29733. 2011
  3. doi Effect of relaxin on human sperm functions
    Alberto Ferlin
    University of Padova, Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Center for Male Gamete Cryopreservation, Padova, Italy
    J Androl 33:474-82. 2012
  4. ncbi Androgens modulate osteocalcin release by human visceral adipose tissue
    Carlo Foresta
    Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete CryopreservationEndocrine Metabolic Laboratory A S, Internal Medicine 3, University of PadovaEURAC Institute of Mountain Emergency Medicine G S, Bozen BolzanoDepartment of Oncological and Surgical Sciences, Clinical Surgery II A B, University Hospital of PadovaDepartment of Laboratory Medicine M P, University Hospital of Padova, Padova, Italy
    Clin Endocrinol (Oxf) 75:64-9. 2011
  5. doi Evidence for osteocalcin production by adipose tissue and its role in human metabolism
    Carlo Foresta
    Department of Histology, Internal Medicine 3, University of Padova, Italy
    J Clin Endocrinol Metab 95:3502-6. 2010
  6. doi Relaxin stimulates osteoclast differentiation and activation
    Alberto Ferlin
    Section of Clinical Pathology and Center for Male Gamete Cryopreservation, Department of Histology, Microbiology and Medical Biotechnologies, University of Padova, Via Gabelli 63, 35121 Padova, Italy
    Bone 46:504-13. 2010
  7. doi Role of relaxin in human osteoclastogenesis
    Arianna Facciolli
    Department of Histology, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Ann N Y Acad Sci 1160:221-5. 2009
  8. doi INSL3 plays a role in the balance between bone formation and resorption
    Anastasia Pepe
    Department of Histology, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Ann N Y Acad Sci 1160:219-20. 2009
  9. doi New roles for INSL3 in adults
    Alberto Ferlin
    Department of Histology, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Ann N Y Acad Sci 1160:215-8. 2009
  10. doi RXFP1 is expressed on the sperm acrosome, and relaxin stimulates the acrosomal reaction of human spermatozoa
    Lisa Gianesello
    Department of Histology, Section of Clinical Pathology, Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Ann N Y Acad Sci 1160:192-3. 2009

Collaborators

Detail Information

Publications13

  1. ncbi Insulin-like factor 3 gene mutations in testicular dysgenesis syndrome: clinical and functional characterization
    A Ferlin
    Department of Histology, Microbiology and Medical Biotechnologies, Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Mol Hum Reprod 12:401-6. 2006
    ..Although a role for mutations of INSL3 and LGR8 genes in cryptorchidism is reasonable, additional studies are needed to establish an association between the disruption of INSL3 pathway and higher risk of infertility or testicular cancer...
  2. pmc Profiling insulin like factor 3 (INSL3) signaling in human osteoblasts
    Alberto Ferlin
    Section of Clinical Pathology, Department of Histology, Microbiology and Medical Biotechnologies, University of Padova, Padova, Italy
    PLoS ONE 6:e29733. 2011
    ..The aim of this study was to elucidate the INSL3/RXFP2 signaling pathways and targets in human osteoblasts...
  3. doi Effect of relaxin on human sperm functions
    Alberto Ferlin
    University of Padova, Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Center for Male Gamete Cryopreservation, Padova, Italy
    J Androl 33:474-82. 2012
    ..Taken together, these data demonstrate that relaxin influences positively many sperm functions linked to fertilizing ability, and it preserves sperm functionality, with possible practical value in assisted reproduction techniques...
  4. ncbi Androgens modulate osteocalcin release by human visceral adipose tissue
    Carlo Foresta
    Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete CryopreservationEndocrine Metabolic Laboratory A S, Internal Medicine 3, University of PadovaEURAC Institute of Mountain Emergency Medicine G S, Bozen BolzanoDepartment of Oncological and Surgical Sciences, Clinical Surgery II A B, University Hospital of PadovaDepartment of Laboratory Medicine M P, University Hospital of Padova, Padova, Italy
    Clin Endocrinol (Oxf) 75:64-9. 2011
    ..DesiGN, PATIENTS, SETTING: Omental AT (OAT) for in vitro study and blood samples from 91 male patients of Padova University Hospital were used...
  5. doi Evidence for osteocalcin production by adipose tissue and its role in human metabolism
    Carlo Foresta
    Department of Histology, Internal Medicine 3, University of Padova, Italy
    J Clin Endocrinol Metab 95:3502-6. 2010
    ..The adipose tissue (AT), which is an endocrine organ, is linked to several metabolic abnormalities. Undercarboxylated osteocalcin (ucOCN) regulates insulin and adiponectin secretion...
  6. doi Relaxin stimulates osteoclast differentiation and activation
    Alberto Ferlin
    Section of Clinical Pathology and Center for Male Gamete Cryopreservation, Department of Histology, Microbiology and Medical Biotechnologies, University of Padova, Via Gabelli 63, 35121 Padova, Italy
    Bone 46:504-13. 2010
    ....
  7. doi Role of relaxin in human osteoclastogenesis
    Arianna Facciolli
    Department of Histology, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Ann N Y Acad Sci 1160:221-5. 2009
    ..This study shows, for the first time, that relaxin has an effect on bone metabolism, facilitating the differentiation of osteoclasts. A possible role for relaxin in osteolytic bone metastasis is also proposed...
  8. doi INSL3 plays a role in the balance between bone formation and resorption
    Anastasia Pepe
    Department of Histology, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Ann N Y Acad Sci 1160:219-20. 2009
    ..Stimulation of human primary osteoblasts with INSL3 at serial concentrations (1 pM, 1 nM, and 1 microM) induced a dose-dependent increase in osteoblast proliferation and expression of specific osteoblast genes...
  9. doi New roles for INSL3 in adults
    Alberto Ferlin
    Department of Histology, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Ann N Y Acad Sci 1160:215-8. 2009
    ..This study identified for the first time a role for INSL3 in adults, demonstrating a modulating effect on bone metabolism and linking RXFP2 gene mutations with human osteoporosis...
  10. doi RXFP1 is expressed on the sperm acrosome, and relaxin stimulates the acrosomal reaction of human spermatozoa
    Lisa Gianesello
    Department of Histology, Section of Clinical Pathology, Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    Ann N Y Acad Sci 1160:192-3. 2009
    ..These data suggest a physiological role on sperm for relaxin produced by the prostate and/or the female genital tract...
  11. pmc Mutations in the insulin-like factor 3 receptor are associated with osteoporosis
    Alberto Ferlin
    Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Male Gamete Cryopreservation, University of Padova, Padova, Italy
    J Bone Miner Res 23:683-93. 2008
    ..The aim of this study was to verify whether reduced INSL3 activity could cause or contribute to some signs of hypogonadism, such as reduced BMD, currently attributed to testosterone deficiency...
  12. ncbi T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane
    Natalia V Bogatcheva
    Dept of Ob Gyn, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Am J Physiol Endocrinol Metab 292:E138-44. 2007
    ..The structural alterations of both LRRs and LDLa of the ligand-binding part of LGR8 cause the inability of receptor to express on the cell surface membrane and might be responsible for the abnormal testicular phenotype in patients...
  13. ncbi Effects of type 5-phosphodiesterase inhibition on energy metabolism and mitochondrial biogenesis in human adipose tissue ex vivo
    L De Toni
    Department of Histology, Microbiology and Medical Biotechnologies, Section of Clinical Pathology and Centre for Human Reproduction Pathology, University of Padua, Via Gabelli 63, 35121 Padua, Italy
    J Endocrinol Invest 34:738-41. 2011
    ..AT harbors the whole molecular signaling pathway of NO, together with type 5-phosphodiesterase (PDE- 5), the main cGMP catabolising enzyme...