M Gacci

Summary

Country: Italy

Publications

  1. ncbi Urinary symptoms, quality of life and sexual function in patients with benign prostatic hypertrophy before and after prostatectomy: a prospective study
    M Gacci
    Department of Urology, University of Florence, V Masaccio No 102, 50132 Florence, Italy
    BJU Int 91:196-200. 2003
  2. doi Vardenafil can improve continence recovery after bilateral nerve sparing prostatectomy: results of a randomized, double blind, placebo-controlled pilot study
    Mauro Gacci
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy
    J Sex Med 7:234-43. 2010
  3. ncbi Management of benign prostatic hyperplasia: role of phosphodiesterase-5 inhibitors
    M Gacci
    Department of Urology, University of Florence, Careggi Hospital, Viale Pieraccini 18, 50139, Florence, Italy
    Drugs Aging 31:425-39. 2014
  4. doi The impact of prior TURP on radical prostatectomy surgical margins: a multicenter analysis
    Mauro Gacci
    Department of Urology, University of Florence, Italy
    Urol Int 91:62-8. 2013
  5. doi External validation of the updated nomogram predicting lymph node invasion in patients with prostate cancer undergoing extended pelvic lymph node dissection
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    Urol Int 90:277-82. 2013
  6. doi Metabolic syndrome and lower urinary tract symptoms: the role of inflammation
    M Gacci
    Department of Urology, Careggi Hospital, University of Florence, Florence, Italy
    Prostate Cancer Prostatic Dis 16:101-6. 2013
  7. pmc Quality of life in women undergoing urinary diversion for bladder cancer: results of a multicenter study among long-term disease-free survivors
    Mauro Gacci
    Urologic Clinic I, University of Florence, AOU Careggi, Florence, Italy
    Health Qual Life Outcomes 11:43. 2013
  8. doi A randomized, placebo-controlled study to assess safety and efficacy of vardenafil 10 mg and tamsulosin 0.4 mg vs. tamsulosin 0.4 mg alone in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    J Sex Med 9:1624-33. 2012
  9. doi A systematic review and meta-analysis on the use of phosphodiesterase 5 inhibitors alone or in combination with α-blockers for lower urinary tract symptoms due to benign prostatic hyperplasia
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    Eur Urol 61:994-1003. 2012
  10. pmc Urinary and sexual outcomes in long-term (5+ years) prostate cancer disease free survivors after radical prostatectomy
    Mauro Gacci
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy
    Health Qual Life Outcomes 7:94. 2009

Collaborators

Detail Information

Publications47

  1. ncbi Urinary symptoms, quality of life and sexual function in patients with benign prostatic hypertrophy before and after prostatectomy: a prospective study
    M Gacci
    Department of Urology, University of Florence, V Masaccio No 102, 50132 Florence, Italy
    BJU Int 91:196-200. 2003
    ....
  2. doi Vardenafil can improve continence recovery after bilateral nerve sparing prostatectomy: results of a randomized, double blind, placebo-controlled pilot study
    Mauro Gacci
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy
    J Sex Med 7:234-43. 2010
    ..Several trials in men with ED and lower urinary tract symptoms associated with benign prostatic hyperplasia suggest that PDE5-I could improve both erectile function and urinary symptoms...
  3. ncbi Management of benign prostatic hyperplasia: role of phosphodiesterase-5 inhibitors
    M Gacci
    Department of Urology, University of Florence, Careggi Hospital, Viale Pieraccini 18, 50139, Florence, Italy
    Drugs Aging 31:425-39. 2014
    ..All these compounds differ in pharmacokinetic factors, with influence on drug action, and subsequently in the overall safety and efficacy profile. ..
  4. doi The impact of prior TURP on radical prostatectomy surgical margins: a multicenter analysis
    Mauro Gacci
    Department of Urology, University of Florence, Italy
    Urol Int 91:62-8. 2013
    ..To analyze positive surgical margins (PSM) after radical prostatectomy (RP) in the overall population and in patients previously treated with transurethral resection of the prostate (TURP)...
  5. doi External validation of the updated nomogram predicting lymph node invasion in patients with prostate cancer undergoing extended pelvic lymph node dissection
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    Urol Int 90:277-82. 2013
    ....
  6. doi Metabolic syndrome and lower urinary tract symptoms: the role of inflammation
    M Gacci
    Department of Urology, Careggi Hospital, University of Florence, Florence, Italy
    Prostate Cancer Prostatic Dis 16:101-6. 2013
    ..Aim of study is to examine the correlation among pre-operatory LUTS/BPH severity, MetS features and inflammatory infiltrates in prostatectomy specimens...
  7. pmc Quality of life in women undergoing urinary diversion for bladder cancer: results of a multicenter study among long-term disease-free survivors
    Mauro Gacci
    Urologic Clinic I, University of Florence, AOU Careggi, Florence, Italy
    Health Qual Life Outcomes 11:43. 2013
    ..1 months; range 36-122 months)...
  8. doi A randomized, placebo-controlled study to assess safety and efficacy of vardenafil 10 mg and tamsulosin 0.4 mg vs. tamsulosin 0.4 mg alone in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    J Sex Med 9:1624-33. 2012
    ..Safety and efficacy of tamsulosin and vardenafil are well established: however, there is no report regarding combined therapy with these drugs for lower urinary tract symptoms (LUTSs) secondary to benign prostatic hyperplasia (BPH)...
  9. doi A systematic review and meta-analysis on the use of phosphodiesterase 5 inhibitors alone or in combination with α-blockers for lower urinary tract symptoms due to benign prostatic hyperplasia
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    Eur Urol 61:994-1003. 2012
    ..However, the results are inconsistent...
  10. pmc Urinary and sexual outcomes in long-term (5+ years) prostate cancer disease free survivors after radical prostatectomy
    Mauro Gacci
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy
    Health Qual Life Outcomes 7:94. 2009
    ..After long term disease free follow up (FUp) patients reconsider quality of life (QOL) outcomes. Aim of this study is assess QoL in prostate cancer patients who are disease-free at least 5 years after radical prostatectomy (RP)...
  11. pmc Influence of serum testosterone on urinary continence and sexual activity in patients undergoing radical prostatectomy for clinically localized prostate cancer
    M Gacci
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy
    Prostate Cancer Prostatic Dis 13:168-72. 2010
    ..The correlation between basal T and preoperative erectile function and urinary continence underlines the importance of assessing T before RP...
  12. doi Critical analysis of the relationship between sexual dysfunctions and lower urinary tract symptoms due to benign prostatic hyperplasia
    Mauro Gacci
    Department of Urology, University of Florence, Italy
    Eur Urol 60:809-25. 2011
    ..This review focuses on the relationship among sexual dysfunction (SD), lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH), and related therapies...
  13. doi Factors predicting continence recovery 1 month after radical prostatectomy: results of a multicenter survey
    Mauro Gacci
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy
    Int J Urol 18:700-8. 2011
    ..To assess the factors associated with continence recovery 1 month after radical prostatectomy (RP) and to identify the correlation between these factors...
  14. ncbi Quality of life after radical treatment of prostate cancer: validation of the Italian version of the University of California-Los Angeles Prostate Cancer Index
    M Gacci
    Department of Urology, University of Florence, Florence, Italy
    Urology 66:338-43. 2005
    ..To validate an Italian version of the University of California-Los Angeles Prostate Cancer Index (UCLA-PCI)...
  15. doi CXCR3-B expression correlates with tumor necrosis extension in renal cell carcinoma
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    J Urol 181:843-8. 2009
    ....
  16. doi Predictors of quality of life after radical treatment for prostate cancer
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    Urol Int 80:231-6. 2008
    ....
  17. ncbi Long-term delayed extrusion of a penile prosthesis
    Mauro Gacci
    Department of Urology, University of Florence, Italy
    Arch Ital Urol Androl 79:41-2. 2007
    ..A manual removal of the eroded cylinder under local anaesthesia was achieved...
  18. ncbi Visual assessment of uroflowmetry curves: description and interpretation by urodynamists
    Mauro Gacci
    Department of Urology, University of Florence, Via Masaccio 102, 50132, Florence, Italy
    World J Urol 25:333-7. 2007
    ..Flow curves from healthy men or from patients with urethral stricture or benign prostatic obstruction are easily recognizable. Long experience and daily practice may make the difference in the assessment of uroflowmetry curves...
  19. ncbi Intravesical gemcitabine in BCG-refractory T1G3 transitional cell carcinoma of the bladder: a pilot study
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    Urol Int 76:106-11. 2006
    ..The aim of this pilot study is to analyze the safety and short-term efficacy of gemcitabine (GEM) as salvage intravesical therapy in a very selected population of bacille Calmette-Guérin (BCG)-resistant T1G3 patients...
  20. ncbi Renal cell carcinoma metastatic to the breast and breast cancer metastatic to the kidney: two rare solitary metastases
    Mauro Gacci
    Department of Urology, University of Florence, Florence, Italy
    Breast J 11:351-2. 2005
  21. ncbi PSA recurrence after brachytherapy for seed misplacement: a double-blind radiologic and pathologic work-up after salvage prostatectomy
    M Gacci
    Department of Urology, University of Florence, Florence, Italy
    Prostate Cancer Prostatic Dis 11:99-101. 2008
    ..This case is indicative of tumor relapse occurring for seed migration after good initial positioning...
  22. ncbi Giant stone in enterocystoplasty
    M Gacci
    Department of Urology, University of Florence, Italy
    Urol Int 75:181-3. 2005
    ..The case report and an accurate literature review are reported. The incidence, risk factors, pathophysiology and treatment options are analyzed...
  23. ncbi Pre and postoperative quantitative detection of fragments of cytokeratins 8 and 18 (UBC IRMA) as markers of early recurrence of superficial bladder tumor
    Mauro Gacci
    Clinica Urologica, Universita di Firenze
    Arch Ital Urol Androl 78:5-10. 2006
    ..The aim of this study is to evaluate the usefulness of the pre and post operative UBC test to detect early recurrences of a bladder tumor in the first year after the transurethral resection of a bladder tumor...
  24. ncbi Diagnostic imaging work-up for disease relapse after radical treatment for prostate cancer: how to differentiate local from systemic disease? The urologist point of view
    R Schiavina
    Department of Urology, University of Bologna, Bologna, S Orsola Malpighi Hospital, Italy
    Rev Esp Med Nucl Imagen Mol 32:310-3. 2013
    ..Low sensitivity, costs, availability of technologies and confirmation of the results remain the major limitations in most cases...
  25. doi Prognostic role of histological necrosis for nonmetastatic clear cell renal cell carcinoma: correlation with pathological features and molecular markers
    Andrea Minervini
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy
    J Urol 180:1284-9. 2008
    ..Also, we further investigated its pathogenesis by correlating this tumor feature with other pathological characteristics and molecular markers related to the von Hippel Lindau-hypoxia inducible factor pathway and to tumor proliferation...
  26. ncbi Vardenafil improves urodynamic parameters in men with spinal cord injury: results from a single dose, pilot study
    Mauro Gacci
    Urology Unit, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
    J Urol 178:2040-3; discussion 2044. 2007
    ..We assessed urodynamic changes after vardenafil administration in spinal cord injured male patients on oxybutynin treatment...
  27. ncbi Imperative indications for conservative surgery for renal cell carcinoma: 20 years' experience
    M Gacci
    Department of Urology, University of Florence, Viale Pieraccini 18, I-50139 Florence, Italy
    Urol Int 67:203-8. 2001
    ..Tumor diameter and stage, incidental or symptomatic tumor presentation and specific indication for conservative surgery determine the prognosis...
  28. ncbi Intravesical migration of AMS 800 artificial urinary sphincter and stone formation in a patient who underwent radical prostatectomy
    R Bartoletti
    Department of Urology, Universitie of Florence, Italy
    Urol Int 64:167-8. 2000
    ..The remaining sphincter components were also removed. Patients with previous radiotherapy are particularly at risk for sphincter erosion, but intravesical displacement of the reservoir is a very uncommon complication...
  29. doi Vardenafil modulates bladder contractility through cGMP-mediated inhibition of RhoA/Rho kinase signaling pathway in spontaneously hypertensive rats
    Annamaria Morelli
    Department of Clinical Physiopathology, University of Florence, Italy
    J Sex Med 6:1594-608. 2009
    ..Phosphorylation/inactivation of RhoA by cyclic guanosine monophosphate (cGMP)-dependent protein kinase (PKG) activity has been described in vascular smooth muscle...
  30. ncbi Pathophysiology of reno-ureteral colic
    F Travaglini
    Department of Urology, University of Florence, Florence, Italy
    Urol Int 72:20-3. 2004
    ..We focused our review on the pathophysiological aspects of reno-ureteral colic and, briefly, on its treatment...
  31. doi Acute vardenafil administration improves bladder oxygenation in spontaneously hypertensive rats
    Annamaria Morelli
    Department of Clinical Physiopathology, University of Florence, Florence, Italy
    J Sex Med 7:107-20. 2010
    ..In human bladder, phosphodiesterase type 5 (PDE5) is present not only in the muscular wall but also in the vascular beds, suggesting a role for PDE5 inhibitors in favoring bladder blood flow and tissue oxygenation...
  32. ncbi Characterization and functional role of androgen-dependent PDE5 activity in the bladder
    Sandra Filippi
    Andrology Unit, Department of Clinical Physiopathology, University of Florence, Viale G Pieraccini 6, 50139 Florence, Italy
    Endocrinology 148:1019-29. 2007
    ....
  33. doi Characterization of phosphodiesterase type 5 expression and functional activity in the human male lower urinary tract
    Benedetta Fibbi
    Andrology and Sexual Medicine Unit, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    J Sex Med 7:59-69. 2010
    ..PDE5 is highly expressed in rat and human bladder, where it regulates cyclic guanosine monophosphate (cGMP) degradation, muscle tone, and proliferation...
  34. doi Opposite effects of tamoxifen on metabolic syndrome-induced bladder and prostate alterations: a role for GPR30/GPER?
    P Comeglio
    Sexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy
    Prostate 74:10-28. 2014
    ..In addition to ERs, GPR30/GPER is able to mediate several estrogenic non-genomic actions...
  35. ncbi Intravesical gemcitabine therapy for superficial transitional cell carcinoma: results of a Phase II prospective multicenter study
    Riccardo Bartoletti
    Department of Urology, University of Florence, Florence, Italy
    Urology 66:726-31. 2005
    ..To determine the tolerability and efficacy after 1 year of weekly intravesical gemcitabine therapy in patients with intermediate-risk and high-risk superficial transitional cell carcinoma...
  36. doi Elective segmental ureterectomy for transitional cell carcinoma of the ureter: long-term follow-up in a series of 73 patients
    Alchiede Simonato
    Department of Urology L Giuliani, University of Genoa, Genoa, Italy
    BJU Int 110:E744-9. 2012
    ..We report our series on 73 patients treated with Kidney Sparing Surgery for UUT TCC. Good results have been achieved in terms of oncological outcome comparing this conservative approach to the radical nephrourectomy...
  37. doi The relationship of testosterone to prostate-specific antigen in men with sexual dysfunction
    Giovanni Corona
    Andrology Unit, Department of Clinical Physiopathology, University of Florence, Florence, Italy
    J Sex Med 7:284-92. 2010
    ..Concern about a testosterone (T)-induced prostate-specific antigen (PSA) increase is often perceived as one of the main limitations in treating hypogonadism even when it is symptomatic, such as in subjects with sexual dysfunction (SD)...
  38. ncbi The dilemma of localizing disease relapse after radical treatment for prostate cancer: which is the value of the actual imaging techniques?
    R Schiavina
    Department of Urology, University of Bologna, Bologna, S Orsola Malpighi Hospital, Italy
    Curr Radiopharm 6:92-5. 2013
    ..The aim of the present paper is to evaluate the management of patients with BCR after radical treatment of PCa from the urologist point of view. ..
  39. ncbi High CXCL10 expression in rejected kidneys and predictive role of pretransplant serum CXCL10 for acute rejection and chronic allograft nephropathy
    Elena Lazzeri
    Center for Research, Transfer and High Education MCINDENT, Florence, Italy
    Transplantation 79:1215-20. 2005
    ..Several experimental models have shown that CXCL10 is required for initiation and development of graft failure caused by both acute and chronic rejection...
  40. ncbi Late relapse in testicular germ cell tumors
    Beatrice Detti
    Institute of Radiotherapy, University of Florence, Florence, Italy
    Tumori 93:428-31. 2007
    ..Analysis of patients with late relapse of testicular germ cell tumors (GCTs) with reports on clinicopathological features and outcomes...
  41. doi Management of Stage II testicular seminoma over a period of 40 years
    Beatrice Detti
    Department of Clinical Pathophysiology, Radiotherapy Unit, University of Florence, Florence, Italy
    Urol Oncol 27:534-8. 2009
    ..To review the treatment, toxicity, and outcomes in patients with Stage II seminoma after orchidectomy...
  42. ncbi The association between varicocele, premature ejaculation and prostatitis symptoms: possible mechanisms
    Francesco Lotti
    Andrology Unit, Department of Clinical Physiopathology, University of Florence, Florence 50139, Italy
    J Sex Med 6:2878-87. 2009
    ..No study has ever systematically evaluated the impact of varicocele on sexual function...
  43. ncbi Localized prostate cancer treated with intensity-modulated radiotherapy
    Lorenzo Livi
    Radiotherapy Department, Florence University, Italy
    Tumori 92:197-201. 2006
    ..The aim of this analysis was to describe the acute and when possible late toxicity and the feasibility on using intensity-modulated radiotherapy into our routine work...