Nicolino Ruperto

Summary

Affiliation: G. Gaslini Institute
Country: Italy

Publications

  1. ncbi request reprint Cyclosporine A in juvenile idiopathic arthritis. Results of the PRCSG/PRINTO phase IV post marketing surveillance study
    N Ruperto
    IRCCS G Gaslini, Pediatria II Reumatologia, PRINTO, Genova, Italy
    Clin Exp Rheumatol 24:599-605. 2006
  2. ncbi request reprint The Paediatric Rheumatology International Trials Organization (PRINTO)
    N Ruperto
    IRCCS G Gaslini, Pediatria, Reumatologia, PRINTO, Genova, Italy
    Lupus 16:670-6. 2007
  3. ncbi request reprint A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis
    Nicolino Ruperto
    IRCCS, Istituto G Gaslini, Genoa, Italy
    Arthritis Rheum 56:3096-106. 2007
  4. doi request reprint Development and validation of a composite disease activity score for juvenile idiopathic arthritis
    Alessandro Consolaro
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, and the Università degli Studi di Verona, Verona, Italy
    Arthritis Rheum 61:658-66. 2009
  5. doi request reprint Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
    Nicolino Ruperto
    Istituto Giannina Gaslini, Pediatria II, Reumatologia, Paediatric Rheumatology International Trials Organisation PRINTO Coordinating Center, Genoa, Italy
    N Engl J Med 367:2396-406. 2012
  6. pmc Periodic fever syndromes in Eastern and Central European countries: results of a pediatric multinational survey
    Natasa Toplak
    Department of Allergology, Rheumatology and Clinical Immunology, University Children s Hospital, University Medical Centre Ljubljana, Slovenia
    Pediatr Rheumatol Online J 8:29. 2010
  7. ncbi request reprint Preliminary core sets of measures for disease activity and damage assessment in juvenile systemic lupus erythematosus and juvenile dermatomyositis
    Nicolino Ruperto
    IRCCS G Gasalini, Pediatria II, Genova, Italy
    Rheumatology (Oxford) 42:1452-9. 2003
  8. ncbi request reprint The Pediatric Rheumatology International Trials Organization/American College of Rheumatology provisional criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus: prospective validation of the definition of improvement
    Nicolino Ruperto
    Pediatric Rheumatology International Trials Organization, IRCCS G Gaslini, Università di Genova Pediatria II Reumatologia, 5 Largo Gaslini, 16147 Genoa, Italy
    Arthritis Rheum 55:355-63. 2006
  9. pmc A randomized, double-blind, placebo-controlled trial of paracetamol and ketoprofren lysine salt for pain control in children with pharyngotonsillitis cared by family pediatricians
    Nicolino Ruperto
    IRCCS G Gaslini, Pediatria II, Reumatologia, PRINTO, Genoa, Italy
    Ital J Pediatr 37:48. 2011
  10. doi request reprint A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features
    Nicolino Ruperto
    IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 64:557-67. 2012

Detail Information

Publications78

  1. ncbi request reprint Cyclosporine A in juvenile idiopathic arthritis. Results of the PRCSG/PRINTO phase IV post marketing surveillance study
    N Ruperto
    IRCCS G Gaslini, Pediatria II Reumatologia, PRINTO, Genova, Italy
    Clin Exp Rheumatol 24:599-605. 2006
    ..To investigate the clinical use patterns, clinical effect and safety of cyclosporine A (CSA) in juvenile idiopathic arthritis (JIA) in the setting of routine clinical care...
  2. ncbi request reprint The Paediatric Rheumatology International Trials Organization (PRINTO)
    N Ruperto
    IRCCS G Gaslini, Pediatria, Reumatologia, PRINTO, Genova, Italy
    Lupus 16:670-6. 2007
    ..The definition is now proposed for use in JSLE clinical trials, and may help physicians to decide if a child with SLE has responded adequately to therapy...
  3. ncbi request reprint A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis
    Nicolino Ruperto
    IRCCS, Istituto G Gaslini, Genoa, Italy
    Arthritis Rheum 56:3096-106. 2007
    ..To evaluate the safety and efficacy of infliximab in the treatment of juvenile rheumatoid arthritis (JRA)...
  4. doi request reprint Development and validation of a composite disease activity score for juvenile idiopathic arthritis
    Alessandro Consolaro
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, and the Università degli Studi di Verona, Verona, Italy
    Arthritis Rheum 61:658-66. 2009
    ..To develop and validate a composite disease activity score for juvenile idiopathic arthritis (JIA), the Juvenile Arthritis Disease Activity Score (JADAS)...
  5. doi request reprint Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
    Nicolino Ruperto
    Istituto Giannina Gaslini, Pediatria II, Reumatologia, Paediatric Rheumatology International Trials Organisation PRINTO Coordinating Center, Genoa, Italy
    N Engl J Med 367:2396-406. 2012
    ..Interleukin-1 is pivotal in the pathogenesis of systemic juvenile idiopathic arthritis (JIA). We assessed the efficacy and safety of canakinumab, a selective, fully human, anti-interleukin-1β monoclonal antibody, in two trials...
  6. pmc Periodic fever syndromes in Eastern and Central European countries: results of a pediatric multinational survey
    Natasa Toplak
    Department of Allergology, Rheumatology and Clinical Immunology, University Children s Hospital, University Medical Centre Ljubljana, Slovenia
    Pediatr Rheumatol Online J 8:29. 2010
    ..abstract:..
  7. ncbi request reprint Preliminary core sets of measures for disease activity and damage assessment in juvenile systemic lupus erythematosus and juvenile dermatomyositis
    Nicolino Ruperto
    IRCCS G Gasalini, Pediatria II, Genova, Italy
    Rheumatology (Oxford) 42:1452-9. 2003
    ..To identify preliminary core sets of outcome variables for disease activity and damage assessment in juvenile systemic lupus erythematosus (JSLE) and juvenile dermatomyositis (JDM)...
  8. ncbi request reprint The Pediatric Rheumatology International Trials Organization/American College of Rheumatology provisional criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus: prospective validation of the definition of improvement
    Nicolino Ruperto
    Pediatric Rheumatology International Trials Organization, IRCCS G Gaslini, Università di Genova Pediatria II Reumatologia, 5 Largo Gaslini, 16147 Genoa, Italy
    Arthritis Rheum 55:355-63. 2006
    ....
  9. pmc A randomized, double-blind, placebo-controlled trial of paracetamol and ketoprofren lysine salt for pain control in children with pharyngotonsillitis cared by family pediatricians
    Nicolino Ruperto
    IRCCS G Gaslini, Pediatria II, Reumatologia, PRINTO, Genoa, Italy
    Ital J Pediatr 37:48. 2011
    ..To evaluate the analgesic effect and tolerability of paracetamol syrup compared to placebo and ketoprofen lysine salt in children with pharyngotonsillitis cared by family pediatricians...
  10. doi request reprint A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features
    Nicolino Ruperto
    IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 64:557-67. 2012
    ..To assess dosing, preliminary safety, and efficacy of canakinumab, a fully human anti-interleukin-1β (anti-IL-1β) antibody, in children with systemic juvenile idiopathic arthritis (JIA) and active systemic features...
  11. doi request reprint The provisional Paediatric Rheumatology International Trials Organisation/American College of Rheumatology/European League Against Rheumatism Disease activity core set for the evaluation of response to therapy in juvenile dermatomyositis: a prospective va
    Nicolino Ruperto
    IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 59:4-13. 2008
    ..To validate a core set of outcome measures for the evaluation of response to treatment in patients with juvenile dermatomyositis (DM)...
  12. doi request reprint Criteria to define response to therapy in paediatric rheumatic diseases
    Nicolino Ruperto
    IRCCS G Gaslini, Pediatria II, Reumatologia, Pædiatric Rheumatology International Trials Organisation PRINTO, Genoa, Italy
    Eur J Clin Pharmacol 67:125-31. 2011
    ....
  13. doi request reprint Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial
    Nicolino Ruperto
    IRCCS G Gaslini, PRINTO, Genoa, Italy
    Lancet 372:383-91. 2008
    ..We aimed to assess the safety and efficacy of abatacept, a selective T-cell costimulation modulator, in children with juvenile idiopathic arthritis who had failed previous treatments...
  14. ncbi request reprint Consensus procedures and their role in pediatric rheumatology
    Nicolino Ruperto
    IRCCS G Gaslini, Pediatria II PRINTO, University of Genoa, Largo Gaslini, 5, 16147 Genova, Italy
    Curr Rheumatol Rep 10:142-6. 2008
    ....
  15. doi request reprint Abatacept improves health-related quality of life, pain, sleep quality, and daily participation in subjects with juvenile idiopathic arthritis
    Nicolino Ruperto
    Universita di Genova, Genoa, Italy
    Arthritis Care Res (Hoboken) 62:1542-51. 2010
    ..To assess health-related quality of life (HRQOL) in abatacept-treated children/adolescents with juvenile idiopathic arthritis (JIA)...
  16. doi request reprint Network in pediatric rheumatology: the example of the Pediatric Rheumatology International Trials Organization
    Nicolino Ruperto
    IRCCS Istituto G Gaslini, Pediatria II, Reumatologia, Genoa, Italy
    World J Pediatr 4:186-91. 2008
    ..The research aimed at studying new therapeutic approaches is difficult because of logistic, methodological and ethical problems...
  17. pmc The Paediatric Rheumatology International Trials Organisation provisional criteria for the evaluation of response to therapy in juvenile dermatomyositis
    Nicolino Ruperto
    Paediatric Rheumatology International Trials Organisation, Genoa, Italy
    Arthritis Care Res (Hoboken) 62:1533-41. 2010
    ..To develop a provisional definition for the evaluation of response to therapy in juvenile dermatomyositis (DM) based on the Paediatric Rheumatology International Trials Organisation juvenile DM core set of variables...
  18. doi request reprint EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part I: Overall methodology and clinical characterisation
    Nicolino Ruperto
    Paediatric Rheumatology INternational Trials Organisation PRINTO, IRCCS G Gaslini, Universita di Genova, Pediatria II Reumatologia, EULAR Centre of Excellence in Rheumatology 2008 2013, Largo Gaslini, 5, Genova 16147, Italy
    Ann Rheum Dis 69:790-7. 2010
    ....
  19. pmc Long-term efficacy and safety of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis: findings from an open-label treatment extension
    Nicolino Ruperto
    IRCCS Istituto G Gaslini, Pediatria II PRINTO, Largo Gaslini 5, EULAR Centre of Excellence in Rheumatology 2008 13, Genoa, Italy
    Ann Rheum Dis 69:718-22. 2010
    ..To assess the long-term efficacy and safety of infliximab plus methotrexate in juvenile rheumatoid arthritis (JRA)...
  20. ncbi request reprint A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate
    Nicolino Ruperto
    IRCCS G Gaslini, University of Genoa, Genoa, Italy
    Arthritis Rheum 50:2191-201. 2004
    ..5 mg/m(2)/week)...
  21. ncbi request reprint International research networks in pediatric rheumatology: the PRINTO perspective
    Nicolino Ruperto
    IRCCS G Gaslini, Universita di Genova, Pediatria II Reumatologia, Genova, Italy
    Curr Opin Rheumatol 16:566-70. 2004
    ..The purpose of this review is to highlight the problems and possible solutions for the conduct of international collaborative research for pediatric rheumatic diseases...
  22. ncbi request reprint The Pediatric Rheumatology International Trials Organization criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus: prospective validation of the disease activity core set
    Nicolino Ruperto
    Pediatric Rheumatology International Trials Organization PRINTO, IRCCS G Gaslini, Universita di Genova, Pediatria II Reumatologia, Largo Gaslini, Genoa, Italy
    Arthritis Rheum 52:2854-64. 2005
    ..To validate and promulgate a core set of outcome measures for the evaluation of response to treatment in patients with juvenile systemic lupus erythematosus (SLE)...
  23. ncbi request reprint A randomized, double-blind clinical trial of two doses of meloxicam compared with naproxen in children with juvenile idiopathic arthritis: short- and long-term efficacy and safety results
    Nicolino Ruperto
    IRCCS G Gaslini, Pediatria II, Reumatologia, Genoa, Italy
    Arthritis Rheum 52:563-72. 2005
    ....
  24. pmc PRINTO/PRES international website for families of children with rheumatic diseases: www.pediatric-rheumatology.printo.it
    N Ruperto
    Paediatric Rheumatology INternational Trials Organisation PRINTO, IRCCS G Gaslini, Pediatria II Reumatologia, Largo Gaslini, 5, 16147 Genova, Italy
    Ann Rheum Dis 64:1101-6. 2005
    ..To prepare a website for families and health professionals containing up to date information about paediatric rheumatic diseases (PRD)...
  25. ncbi request reprint Agreement between multi-dimensional and renal-specific response criteria in patients with juvenile systemic lupus erythematosus and renal disease
    Nicolino Ruperto
    IRCCS G Gaslini, Pediatria II, Reumatologia, Paediatric Rheumatology INternational Trials Organisation PRINTO, Genova, Italy
    Clin Exp Rheumatol 28:424-33. 2010
    ..To evaluate change over time and level of agreement of renal-specific and multi-dimensional measures in juvenile systemic lupus erythematosus (SLE) with renal disease...
  26. ncbi request reprint Long-term safety and efficacy of abatacept in children with juvenile idiopathic arthritis
    Nicolino Ruperto
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 62:1792-802. 2010
    ..Here, we report results from the long-term extension (LTE) phase of that study...
  27. ncbi request reprint Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: the Pediatric Rheumatology International Trials Organization multinational quality of life cohort study
    Sheila Oliveira
    IRCCS G Gaslini, Pediatria II, Reumatologia, Pediatric Rheumatology International Trials Organization, Genoa, Italy
    Arthritis Rheum 57:35-43. 2007
    ..To investigate the proxy-reported health-related quality of life (HRQOL) and its determinants in patients with juvenile idiopathic arthritis (JIA)...
  28. doi request reprint Development and testing of reduced joint counts in juvenile idiopathic arthritis
    Anna Bazso
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Largo G Gaslini 5, 16147 Genova, Italy
    J Rheumatol 36:183-90. 2009
    ..To develop and test reduced joint counts in children with juvenile idiopathic arthritis (JIA)...
  29. doi request reprint Development and initial validation of composite parent- and child-centered disease assessment indices for juvenile idiopathic arthritis
    Alessandro Consolaro
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Care Res (Hoboken) 63:1262-70. 2011
    ....
  30. ncbi request reprint Health-related quality of life in juvenile-onset systemic lupus erythematosus and its relationship to disease activity and damage
    Nicolino Ruperto
    Universita di Genova, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 51:458-64. 2004
    ..To assess the health-related quality of life (HRQL) of patients with juvenile-onset systemic lupus erythematosus (JSLE) and its relationship with disease activity and accumulated damage...
  31. doi request reprint Health-related quality of life of patients with juvenile dermatomyositis: results from the Pediatric Rheumatology International Trials Organisation multinational quality of life cohort study
    Maria Teresa Apaz
    Paediatric Rheumatology International Trials Organisation, Genoa, Italy
    Arthritis Rheum 61:509-17. 2009
    ..To investigate the health-related quality of life (HRQOL) change over time, as measured by the Child Health Questionnaire (CHQ), and its determinants in patients with active juvenile dermatomyositis (DM)...
  32. ncbi request reprint Comparison of clinical features and drug therapies among European and Latin American patients with juvenile dermatomyositis
    Dinara Guseinova
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    Clin Exp Rheumatol 29:117-24. 2011
    ..To compare the demographic features, presenting manifestations, diagnostic investigations, disease course, and drug therapies of children with juvenile dermatomyositis (JDM) followed in Europe and Latin America...
  33. ncbi request reprint Development and validation of a new short and simple measure of physical function for juvenile idiopathic arthritis
    Giovanni Filocamo
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 57:913-20. 2007
    ..To develop and validate a new short and simple measure of physical function in children with juvenile idiopathic arthritis (JIA)...
  34. ncbi request reprint Physicians' and parents' ratings of inactive disease are frequently discordant in juvenile idiopathic arthritis
    Alessandro Consolaro
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    J Rheumatol 34:1773-6. 2007
    ..To investigate discrepancies between physicians' and parents' ratings of inactive disease in children with juvenile idiopathic arthritis (JIA) and the determinants of the discrepancy...
  35. doi request reprint Assessing current outcomes of juvenile idiopathic arthritis: a cross-sectional study in a tertiary center sample
    Nicoletta Solari
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 59:1571-9. 2008
    ....
  36. doi request reprint Validation of the Childhood Health Assessment Questionnaire in active juvenile systemic lupus erythematosus
    Silvia Meiorin
    IRCCS G Gaslini, Pediatria II, Reumatologia and Paediatric Rheumatology International Trials Organisation, Universita di Genova, Largo Gaslini 5, Genoa, Italy
    Arthritis Rheum 59:1112-9. 2008
    ..To validate the Childhood Health Assessment Questionnaire (C-HAQ) as a measure of disability in patients with active juvenile systemic lupus erythematosus (SLE)...
  37. doi request reprint The PRINTO criteria for clinically inactive disease in juvenile dermatomyositis
    Dragana Lazarevic
    Pediatria II, Reumatologia, Istituto Giannina Gaslini, Genova, Italy
    Ann Rheum Dis 72:686-93. 2013
    ..To develop data-driven criteria for clinically inactive disease on and off therapy for juvenile dermatomyositis (JDM)...
  38. doi request reprint Remission, minimal disease activity, and acceptable symptom state in juvenile idiopathic arthritis: defining criteria based on the juvenile arthritis disease activity score
    Alessandro Consolaro
    Istituto G Gaslini, Genoa, Italy
    Arthritis Rheum 64:2366-74. 2012
    ..To determine cutoff values for defining remission, minimal disease activity, and parent and child acceptable symptom state in juvenile idiopathic arthritis (JIA) using the Juvenile Arthritis Disease Activity Score (JADAS)...
  39. ncbi request reprint Development and validation of a clinical index for assessment of long-term damage in juvenile idiopathic arthritis
    Stefania Viola
    Universita di Genova, IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 52:2092-102. 2005
    ..To develop and validate a clinical measure of articular and extraarticular damage in patients with juvenile idiopathic arthritis (JIA)...
  40. doi request reprint Evaluation of 21-numbered circle and 10-centimeter horizontal line visual analog scales for physician and parent subjective ratings in juvenile idiopathic arthritis
    Giovanni Filocamo
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    J Rheumatol 37:1534-41. 2010
    ..To evaluate the measurement properties of 21-numbered circle visual analog scales (VAS) and traditional 10-cm horizontal line VAS for physician and parent subjective ratings in children with juvenile idiopathic arthritis (JIA)...
  41. doi request reprint Factors associated with achievement of inactive disease in children with juvenile idiopathic arthritis treated with etanercept
    Nicoletta Solari
    Istituto Giannina Gaslini and Università degli Studi di Genova, Genoa, Italy
    J Rheumatol 40:192-200. 2013
    ..To evaluate the rate of inactive disease in children with juvenile idiopathic arthritis (JIA) treated with etanercept, and to identify clinical characteristics associated with attainment of inactive disease...
  42. doi request reprint Parent and child acceptable symptom state in juvenile idiopathic arthritis
    Giovanni Filocamo
    Pediatria II, Istituto G Gaslini, Largo G Gaslini 5, 16147 Genoa, Italy
    J Rheumatol 39:856-63. 2012
    ..To explore the parent and child acceptable symptom state in juvenile arthritis (JA-PASS and JA-CASS, respectively) and estimate the JA-PASS and JA-CASS cutoff values for outcome measures...
  43. doi request reprint Development and preliminary validation of a paediatric-targeted MRI scoring system for the assessment of disease activity and damage in juvenile idiopathic arthritis
    Clara Malattia
    Correspondence to Dr Clara Malattia, Pediatria II, IRCCS G Gaslini, Largo G Gaslini 5, 16147 Genova, Italy
    Ann Rheum Dis 70:440-6. 2011
    ..To compare the paediatric MRI score with the adult-designed. Outcome Measures in Rheumatology Clinical Trials-Rheumatoid Arthritis MRI Score (RAMRIS), whose suitability for assessing growing joints was tested...
  44. doi request reprint Long-term outcome and prognostic factors of juvenile dermatomyositis: a multinational, multicenter study of 490 patients
    Angelo Ravelli
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini and Università degli Studi di Genoa, Genoa, Italy
    Arthritis Care Res (Hoboken) 62:63-72. 2010
    ..To investigate the long-term outcome and prognostic factors of juvenile dermatomyositis (DM) through a multinational, multicenter study...
  45. ncbi request reprint A new short and simple health-related quality of life measurement for paediatric rheumatic diseases: initial validation in juvenile idiopathic arthritis
    Giovanni Filocamo
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    Rheumatology (Oxford) 49:1272-80. 2010
    ..To develop and validate a new short and simple measure of health-related quality of life (HRQL) in children with juvenile idiopathic arthritis (JIA)...
  46. ncbi request reprint Frequency of radiographic damage and progression in individual joints in children with juvenile idiopathic arthritis
    Gabriella Giancane
    Istituto Giannina Gaslini, Genova, Italy
    Arthritis Care Res (Hoboken) 66:27-33. 2014
    ....
  47. doi request reprint Therapeutic approaches in the treatment of juvenile dermatomyositis in patients with recent-onset disease and in those experiencing disease flare: an international multicenter PRINTO study
    Rachana Hasija
    IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 63:3142-52. 2011
    ..To evaluate response to therapy over a 24-month period in a large prospective international cohort of patients with juvenile dermatomyositis (DM)...
  48. doi request reprint A new approach to clinical care of juvenile idiopathic arthritis: the Juvenile Arthritis Multidimensional Assessment Report
    Giovanni Filocamo
    Pediatria II, Istituto G Gaslini, Largo G Gaslini 5, Genoa, Italy
    J Rheumatol 38:938-53. 2011
    ..To develop and test a new multidimensional questionnaire for assessment of children with juvenile idiopathic arthritis (JIA) in standard clinical care...
  49. doi request reprint An international consensus survey of diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis
    Sergio Davì
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    J Rheumatol 38:764-8. 2011
    ..To identify candidate diagnostic criteria for macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (sJIA) using international consensus formation through a Delphi questionnaire survey...
  50. ncbi request reprint Use of the Sharp and Larsen scoring methods in the assessment of radiographic progression in juvenile idiopathic arthritis
    Federica Rossi
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 55:717-23. 2006
    ..To investigate the applicability of the Sharp and Larsen scoring methods for radiographic damage in juvenile idiopathic arthritis (JIA)...
  51. ncbi request reprint Defining criteria for high disease activity in juvenile idiopathic arthritis based on the Juvenile Arthritis Disease Activity Score
    Alessandro Consolaro
    Istituto Giannina Gaslini, Genova, Italy
    Ann Rheum Dis 73:1380-3. 2014
    ..To determine cutoff values for defining the state of high disease activity (HDA) in juvenile idiopathic arthritis (JIA) using the Juvenile Arthritis Disease Activity Score (JADAS)...
  52. pmc Agreement between physicians and parents in rating functional ability of children with juvenile idiopathic arthritis
    Elena Palmisani
    Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G, Gaslini, Genova, Italy
    Pediatr Rheumatol Online J 5:23. 2007
    ..To investigate concordance between physicians and parents in rating the degree of functional ability of children with juvenile idiopathic arthritis (JIA)...
  53. ncbi request reprint Predictors of poor response to methotrexate in polyarticular-course juvenile idiopathic arthritis: analysis of the PRINTO methotrexate trial
    Iris Vilca
    IRCCS G Gaslini, Pediatria II, Reumatologia, PRINTO, Genova, Italy
    Ann Rheum Dis 69:1479-83. 2010
    ..To determine whether baseline demographic, clinical, articular and laboratory variables predict methotrexate (MTX) poor response in polyarticular-course juvenile idiopathic arthritis...
  54. doi request reprint Macrophage activation syndrome in juvenile systemic lupus erythematosus: a multinational multicenter study of thirty-eight patients
    Alessandro Parodi
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 60:3388-99. 2009
    ..To describe the clinical and laboratory features of macrophage activation syndrome as a complication of juvenile systemic lupus erythematosus (SLE)...
  55. ncbi request reprint Performance of Birmingham Vasculitis Activity Score and disease extent index in childhood vasculitides
    Erkan Demirkaya
    IRCCS G Gaslini, Pediatria II, Reumatologia, PRINTO, Genova, Italy
    Clin Exp Rheumatol 30:S162-8. 2012
    ..To evaluate the performance of the Birmingham Vasculitis Activity Score (BVAS) v3 and the Disease Extent Index (DEI) for the assessment of disease activity in 4 primary childhood (c-) systemic vasculitides...
  56. ncbi request reprint Adapted versions of the Sharp/van der Heijde score are reliable and valid for assessment of radiographic progression in juvenile idiopathic arthritis
    Angelo Ravelli
    Università degli Studi di Genoa, and IRCCS, Istituto G Gaslini, Genoa, Italy
    Arthritis Rheum 56:3087-95. 2007
    ..To develop adapted versions of the Sharp/van der Heijde radiographic scoring system for use in juvenile idiopathic arthritis (JIA), and to investigate their validity in JIA patients with polyarticular disease...
  57. ncbi request reprint A proposal for a pediatric version of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index based on the analysis of 1,015 patients with juvenile-onset systemic lupus erythematosus
    Raul Gutiérrez-Suárez
    IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 54:2989-96. 2006
    ....
  58. doi request reprint Antinuclear antibody-positive patients should be grouped as a separate category in the classification of juvenile idiopathic arthritis
    Angelo Ravelli
    IRCCS G Gaslini and Università degli Studi di Genova, Genoa, Italy
    Arthritis Rheum 63:267-75. 2011
    ....
  59. doi request reprint Networking in paediatrics: the example of the Paediatric Rheumatology International Trials Organisation (PRINTO)
    Nicolino Ruperto
    Pediatria II, Reumatologia, University of Genoa, EULAR Centre of Excellence in Rheumatology 2008 13, IRCCS G Gaslini, Largo G Gaslini 5, Genoa, Italy
    Arch Dis Child 96:596-601. 2011
    ..The PRINTO and PRCSG networks can be seen as a model for international co-operation in other paediatric subspecialties...
  60. ncbi request reprint Whole-body MRI in the assessment of disease activity in juvenile dermatomyositis
    Clara Malattia
    Pediatria II, Istituto Giannina Gaslini, Genova, Italy
    Ann Rheum Dis 73:1083-90. 2014
    ..To compare whole-body MRI (WB-MRI) with clinical examination in the assessment of disease activity in juvenile dermatomyositis (JDM)...
  61. doi request reprint A11: Assessment of Radiographic Progression in Patients With Polyarticular-Course Juvenile Idiopathic Arthritis Treated With Tocilizumab: 2-Year Data From CHERISH
    Angelo Ravelli
    PRINTO, Genoa, Italy
    Arthritis Rheumatol 66:S17-8. 2014
    ..This analysis investigated the progression of radiographic joint damage in patients with pcJIA treated with TCZ for up to 104 weeks in CHERISH...
  62. doi request reprint A66: Assessment of Radiographic Progression in Patients With Systemic Juvenile Idiopathic Arthritis Treated With Tocilizumab: 2-Year Results From the TENDER Trial
    Clara Malattia
    PRINTO, Genoa, Italy
    Arthritis Rheumatol 66:S96-7. 2014
    ..The aim of this study was to investigate the progression of radiographic joint damage in patients with sJIA treated with TCZ for up to 2 years in TENDER...
  63. doi request reprint Impact of the European paediatric legislation in paediatric rheumatology: past, present and future
    Nicolino Ruperto
    Pediatria II e Reumatologia, Istituto G Gaslini Genova, Genova, Italy
    Ann Rheum Dis 72:1893-6. 2013
    ..Future changes might increase the possibility of conducting trials with similar approaches in other paediatric rheumatological conditions and provide evidence-based treatments for children affected by rheumatic diseases. ..
  64. ncbi request reprint Clinical assessment in juvenile dermatomyositis
    Angelo Ravelli
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Universita di Genova, Dipartimento di Pediatria, Italy
    Autoimmunity 39:197-203. 2006
    ....
  65. ncbi request reprint Level of agreement between children, parents, and physicians in rating pain intensity in juvenile idiopathic arthritis
    Pablo Garcia-Munitis
    Unita Operativa Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Universita di Genova, Largo G Gaslini 5, 16147 Genoa, Italy
    Arthritis Rheum 55:177-83. 2006
    ..To investigate the level of agreement between patients, mothers, fathers, and physicians in rating pain intensity in juvenile idiopathic arthritis (JIA), and to identify factors explaining discrepancies between raters...
  66. ncbi request reprint Outcome in juvenile onset systemic lupus erythematosus
    Angelo Ravelli
    Dipartimento di Pediatria, Universita di Genova, Unita Operativa Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Italy
    Curr Opin Rheumatol 17:568-73. 2005
    ..This review summarizes the recent advances in the investigation on survival, accumulated damage, and health-related quality of life in patients with juvenile-onset systemic lupus erythematosus...
  67. ncbi request reprint Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
    Angelo Ravelli
    Department of Pediatrics, Division of Pediatrics II, University of Genoa, Istituto G Gaslini, Largo G Gaslini 5, 16147 Genoa, Italy
    J Pediatr 146:598-604. 2005
    ..To develop diagnostic guidelines for macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (S-JIA)...
  68. ncbi request reprint Assessment of damage in juvenile-onset systemic lupus erythematosus: a multicenter cohort study
    Angelo Ravelli
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 49:501-7. 2003
    ..To investigate the prevalence of cumulative organ damage in patients with juvenile-onset systemic lupus erythematosus (SLE) and its association with demographic and clinical variables, medication use, and quality of life...
  69. ncbi request reprint Emerging drugs to treat juvenile idiopathic arthritis
    Nicolino Ruperto
    IRCCS Istituto G Gaslini Pediatria II, Reumatologia, Genova, Italy
    Expert Opin Emerg Drugs 16:493-505. 2011
    ..Some of the new drugs that are under investigation for RA could also be suitable in the future for improving the treatment of JIA...
  70. ncbi request reprint Adalimumab with or without methotrexate in juvenile rheumatoid arthritis
    Daniel J Lovell
    Cincinnati Children s Hospital Medical Center, Division of Rheumatology, Location E, Rm 2 129, MLC 4010, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    N Engl J Med 359:810-20. 2008
    ..We evaluated the efficacy and safety of adalimumab, a fully human monoclonal anti-TNF antibody, in children with polyarticular-course juvenile rheumatoid arthritis...
  71. doi request reprint Development and validation of a preliminary definition of minimal disease activity in patients with juvenile idiopathic arthritis
    Silvia Magni-Manzoni
    Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S Matteo, Pavia, Italy
    Arthritis Rheum 59:1120-7. 2008
    ..To develop and validate a definition of minimal disease activity (MDA) in patients with juvenile idiopathic arthritis (JIA)...
  72. ncbi request reprint Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis
    Carol A Wallace
    Children s Hospital and Regional Medical Center, Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington 98105, USA
    J Rheumatol 31:2290-4. 2004
    ..To develop preliminary criteria for inactive disease and clinical remission for select categories of juvenile idiopathic arthritis (JIA), and to decide what such clinical states should predict in terms of probability of disease recurrence...
  73. ncbi request reprint Is minimal clinically important difference relevant for the interpretation of clinical trials in pediatric rheumatic diseases?
    Nicolino Ruperto
    J Rheumatol 34:463-5. 2007
  74. ncbi request reprint The Pediatric Rheumatology European Society/American College of Rheumatology/European League against Rheumatism provisional classification criteria for juvenile systemic sclerosis
    Francesco Zulian
    Dipartimento di Pediatria, University of Padua, Padua, Italy
    Arthritis Rheum 57:203-12. 2007
    ..To develop criteria for the classification of systemic sclerosis (SSc) in children (juvenile SSc)...
  75. ncbi request reprint Reply to letter by Isenberg and Gordon commenting on the Pediatric Rheumatology International Trials Organization criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus
    Nicolino Ruperto
    Arthritis Rheum 54:3723-4. 2006
  76. doi request reprint Performing trials in children with rheumatic diseases: comment on the editorial by Lehman
    Nicolino Ruperto
    Arthritis Rheum 58:1201-2; author reply 1203. 2008
  77. ncbi request reprint Positive family history of psoriasis does not affect the clinical expression and course of juvenile idiopathic arthritis patients with oligoarthritis
    Elena Tsitsami
    IRCCS Policlinico S Matteo, Universita di Pavia, Pavia, Italy
    Arthritis Rheum 49:488-93. 2003
    ..We investigated whether psoriasis in a first or second degree relative influences the clinical expression and course of JIA patients with oligoarthritis...
  78. ncbi request reprint International consensus guidelines for trials of therapies in the idiopathic inflammatory myopathies
    Chester V Oddis
    University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 52:2607-15. 2005